DE69910186D1 - Pharmazeutische zusammensetzung von topiramate - Google Patents
Pharmazeutische zusammensetzung von topiramateInfo
- Publication number
- DE69910186D1 DE69910186D1 DE69910186T DE69910186T DE69910186D1 DE 69910186 D1 DE69910186 D1 DE 69910186D1 DE 69910186 T DE69910186 T DE 69910186T DE 69910186 T DE69910186 T DE 69910186T DE 69910186 D1 DE69910186 D1 DE 69910186D1
- Authority
- DE
- Germany
- Prior art keywords
- topiramate
- pharmaceutical composition
- pharmaceutical
- composition
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Revoked
Links
- KJADKKWYZYXHBB-XBWDGYHZSA-N Topiramic acid Chemical group C1O[C@@]2(COS(N)(=O)=O)OC(C)(C)O[C@H]2[C@@H]2OC(C)(C)O[C@@H]21 KJADKKWYZYXHBB-XBWDGYHZSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 229960004394 topiramate Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/284—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone
- A61K9/2846—Poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Neurosurgery (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Molecular Biology (AREA)
- Pain & Pain Management (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US7677098P | 1998-03-04 | 1998-03-04 | |
US76770P | 1998-03-04 | ||
PCT/US1999/004449 WO1999044581A2 (en) | 1998-03-04 | 1999-03-01 | Pharmaceutical composition of topiramate |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69910186D1 true DE69910186D1 (de) | 2003-09-11 |
DE69910186T2 DE69910186T2 (de) | 2004-07-29 |
Family
ID=22134079
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69910186T Revoked DE69910186T2 (de) | 1998-03-04 | 1999-03-01 | Pharmazeutische zusammensetzung von topiramate |
Country Status (32)
Country | Link |
---|---|
US (4) | US6696091B2 (de) |
EP (1) | EP1066027B1 (de) |
JP (1) | JP2003530295A (de) |
KR (1) | KR20010041592A (de) |
CN (1) | CN100364501C (de) |
AR (3) | AR017984A1 (de) |
AT (1) | ATE246490T1 (de) |
AU (1) | AU763643B2 (de) |
BG (1) | BG64885B1 (de) |
BR (1) | BR9908488A (de) |
CA (1) | CA2322644C (de) |
DE (1) | DE69910186T2 (de) |
DK (1) | DK1066027T3 (de) |
EA (1) | EA200000814A1 (de) |
EE (1) | EE04175B1 (de) |
ES (1) | ES2204109T3 (de) |
HK (1) | HK1032009A1 (de) |
HR (1) | HRP20000563B1 (de) |
HU (1) | HUP0301192A3 (de) |
ID (1) | ID26982A (de) |
IL (2) | IL138032A0 (de) |
MY (1) | MY125821A (de) |
NO (1) | NO20004311L (de) |
NZ (1) | NZ506532A (de) |
PL (1) | PL194559B1 (de) |
PT (1) | PT1066027E (de) |
SK (1) | SK285440B6 (de) |
TR (1) | TR200002541T2 (de) |
TW (1) | TW590778B (de) |
UA (1) | UA65607C2 (de) |
WO (1) | WO1999044581A2 (de) |
ZA (1) | ZA991716B (de) |
Families Citing this family (72)
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US6099865A (en) * | 1998-07-08 | 2000-08-08 | Fmc Corporation | Croscarmellose taste masking |
EP1158950B1 (de) | 1999-02-17 | 2006-01-25 | Ortho-Mcneil Pharmaceutical, Inc. | Antikonvulsive derivate zur behandlung von essentiellem tremor |
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EP2305226B1 (de) * | 1999-06-14 | 2015-05-06 | Vivus, Inc. | Kombinationstherapie zur Behandlung von Schlafapnoe bei Fettleibigkeit |
EP1157682A1 (de) * | 2000-05-25 | 2001-11-28 | Cilag AG | Blisterpackung für Topiramattabletten |
DE60118206T2 (de) * | 2000-07-07 | 2006-12-14 | Ortho-Mcneil Pharmaceutical, Inc. | Antikonvulsive derivate zur behandlung und vorbeugung der entwicklung von typ ii diabetes und syndrom x |
DK1333887T3 (da) | 2000-10-30 | 2006-11-13 | Ortho Mcneil Pharm Inc | Kombinationsbehandling omfattende antidiabetiske og antikonvulsive midler |
US7771749B2 (en) | 2001-07-11 | 2010-08-10 | Monsanto Technology Llc | Lignin-based microparticles for the controlled release of agricultural actives |
US8765167B2 (en) | 2001-10-12 | 2014-07-01 | Monosol Rx, Llc | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
US20190328679A1 (en) | 2001-10-12 | 2019-10-31 | Aquestive Therapeutics, Inc. | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
US7357891B2 (en) | 2001-10-12 | 2008-04-15 | Monosol Rx, Llc | Process for making an ingestible film |
US8603514B2 (en) | 2002-04-11 | 2013-12-10 | Monosol Rx, Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
US8900497B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for making a film having a substantially uniform distribution of components |
US8900498B2 (en) | 2001-10-12 | 2014-12-02 | Monosol Rx, Llc | Process for manufacturing a resulting multi-layer pharmaceutical film |
US10285910B2 (en) | 2001-10-12 | 2019-05-14 | Aquestive Therapeutics, Inc. | Sublingual and buccal film compositions |
US20110033542A1 (en) | 2009-08-07 | 2011-02-10 | Monosol Rx, Llc | Sublingual and buccal film compositions |
US20070281003A1 (en) | 2001-10-12 | 2007-12-06 | Fuisz Richard C | Polymer-Based Films and Drug Delivery Systems Made Therefrom |
US11207805B2 (en) | 2001-10-12 | 2021-12-28 | Aquestive Therapeutics, Inc. | Process for manufacturing a resulting pharmaceutical film |
US20050175690A1 (en) * | 2003-12-29 | 2005-08-11 | David Edgren | Novel drug compositions and dosage forms |
MXPA05001184A (es) * | 2002-07-29 | 2005-09-12 | Johnson & Johnson | Formulaciones y formas de dosificacion para administracion controlada de topiramato. |
US20050232995A1 (en) | 2002-07-29 | 2005-10-20 | Yam Nyomi V | Methods and dosage forms for controlled delivery of paliperidone and risperidone |
KR20050096915A (ko) * | 2002-12-13 | 2005-10-06 | 시락 아게 | 안정한 토피라메이트 제제 |
JP4469846B2 (ja) * | 2003-01-31 | 2010-06-02 | エラン ファーマ インターナショナル,リミティド | ナノ粒子状トピラメート製剤 |
ITMI20031096A1 (it) * | 2003-05-30 | 2004-11-30 | Eurand Spa | Microcapsule per coacervazione contenenti farmaco incorporato nel polimero di rivestimento |
US6949518B1 (en) | 2003-06-25 | 2005-09-27 | Pao-Hsien Chu | Methods for treating macular degeneration with topiramate |
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-
1999
- 1999-01-03 UA UA2000085074A patent/UA65607C2/uk unknown
- 1999-03-01 SK SK1306-2000A patent/SK285440B6/sk not_active IP Right Cessation
- 1999-03-01 ES ES99908594T patent/ES2204109T3/es not_active Expired - Lifetime
- 1999-03-01 PL PL99343894A patent/PL194559B1/pl unknown
- 1999-03-01 US US09/259,718 patent/US6696091B2/en not_active Expired - Lifetime
- 1999-03-01 DK DK99908594T patent/DK1066027T3/da active
- 1999-03-01 CN CNB998035890A patent/CN100364501C/zh not_active Expired - Lifetime
- 1999-03-01 ID IDW20001690A patent/ID26982A/id unknown
- 1999-03-01 WO PCT/US1999/004449 patent/WO1999044581A2/en active IP Right Grant
- 1999-03-01 AU AU27989/99A patent/AU763643B2/en not_active Expired
- 1999-03-01 PT PT99908594T patent/PT1066027E/pt unknown
- 1999-03-01 BR BR9908488-0A patent/BR9908488A/pt not_active Application Discontinuation
- 1999-03-01 TR TR2000/02541T patent/TR200002541T2/xx unknown
- 1999-03-01 IL IL13803299A patent/IL138032A0/xx active IP Right Grant
- 1999-03-01 MY MYPI99000735A patent/MY125821A/en unknown
- 1999-03-01 KR KR1020007009784A patent/KR20010041592A/ko not_active Application Discontinuation
- 1999-03-01 NZ NZ506532A patent/NZ506532A/en not_active IP Right Cessation
- 1999-03-01 AT AT99908594T patent/ATE246490T1/de active
- 1999-03-01 JP JP2000534184A patent/JP2003530295A/ja active Pending
- 1999-03-01 DE DE69910186T patent/DE69910186T2/de not_active Revoked
- 1999-03-01 EE EEP200000503A patent/EE04175B1/xx unknown
- 1999-03-01 EP EP99908594A patent/EP1066027B1/de not_active Revoked
- 1999-03-01 CA CA002322644A patent/CA2322644C/en not_active Expired - Lifetime
- 1999-03-01 EA EA200000814A patent/EA200000814A1/ru unknown
- 1999-03-01 HU HU0301192A patent/HUP0301192A3/hu unknown
- 1999-03-03 ZA ZA9901716A patent/ZA991716B/xx unknown
- 1999-03-03 AR ARP990100895A patent/AR017984A1/es not_active Application Discontinuation
- 1999-03-26 TW TW088103263A patent/TW590778B/zh not_active IP Right Cessation
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2000
- 2000-08-23 IL IL138032A patent/IL138032A/en not_active IP Right Cessation
- 2000-08-29 BG BG104727A patent/BG64885B1/bg unknown
- 2000-08-30 NO NO20004311A patent/NO20004311L/no unknown
- 2000-08-30 HR HR20000563A patent/HRP20000563B1/xx not_active IP Right Cessation
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2001
- 2001-04-18 HK HK01102738A patent/HK1032009A1/xx not_active IP Right Cessation
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2003
- 2003-12-30 US US10/748,764 patent/US7125560B2/en not_active Expired - Lifetime
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2005
- 2005-03-31 AR ARP050101282A patent/AR048457A2/es not_active Application Discontinuation
- 2005-03-31 AR ARP050101281A patent/AR048456A2/es not_active Application Discontinuation
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2006
- 2006-08-25 US US11/467,298 patent/US20060286163A1/en not_active Abandoned
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2007
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Representative=s name: BOEHMERT & BOEHMERT, 28209 BREMEN |
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8331 | Complete revocation |