IT1246383B - Metodo per il mascheramento del sapore di farmaci - Google Patents
Metodo per il mascheramento del sapore di farmaciInfo
- Publication number
- IT1246383B IT1246383B IT02005590A IT2005590A IT1246383B IT 1246383 B IT1246383 B IT 1246383B IT 02005590 A IT02005590 A IT 02005590A IT 2005590 A IT2005590 A IT 2005590A IT 1246383 B IT1246383 B IT 1246383B
- Authority
- IT
- Italy
- Prior art keywords
- pct
- taste
- drugs
- sec
- masking
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Priority Applications (19)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT02005590A IT1246383B (it) | 1990-04-17 | 1990-04-17 | Metodo per il mascheramento del sapore di farmaci |
KR1019910701886A KR0164863B1 (ko) | 1990-04-17 | 1991-04-09 | 약제학적 제형 |
SU915010753A RU2085190C1 (ru) | 1990-04-17 | 1991-04-09 | Твердая лекарственная форма для орального введения фармацевтически активных веществ, имеющих неблагоприятные органолептические свойства |
PCT/EP1991/000689 WO1991016043A1 (en) | 1990-04-17 | 1991-04-09 | Pharmaceutical formulations |
CA002058946A CA2058946C (en) | 1990-04-17 | 1991-04-09 | Formulations for the oral administration of drugs with masked taste |
ES91907609T ES2048594T3 (es) | 1990-04-17 | 1991-04-09 | Formulaciones farmaceuticas. |
DE91907609T DE69100991T2 (de) | 1990-04-17 | 1991-04-09 | Pharmazeutische formulierungen. |
AU76812/91A AU635133B2 (en) | 1990-04-17 | 1991-04-09 | Pharmaceutical formulations |
AT91907609T ATE99927T1 (de) | 1990-04-17 | 1991-04-09 | Pharmazeutische formulierungen. |
EP91907609A EP0477333B1 (en) | 1990-04-17 | 1991-04-09 | Pharmaceutical formulations |
JP50687791A JP3193041B2 (ja) | 1990-04-17 | 1991-04-09 | 医薬製剤 |
DK91907609.1T DK0477333T3 (da) | 1990-04-17 | 1991-04-09 | Farmaceutiske præparater |
US07/776,329 US5409711A (en) | 1990-04-17 | 1991-04-09 | Pharmaceutical formulations |
PT97369A PT97369B (pt) | 1990-04-17 | 1991-04-15 | Processo para a preparacao de formulacoes farmaceutica na qual o sabor do medicamento e disfarcado por meio de revestimento do medicamento com uma membrana polimerica |
NZ237824A NZ237824A (en) | 1990-04-17 | 1991-04-15 | Formulation for oral administration comprising a core of active ingredient coated by a polymer soluble at ph greater than 5 and containing an acidic compound to prevent dissolution of the coating in the mouth |
ZA912793A ZA912793B (en) | 1990-04-17 | 1991-04-15 | Pharmaceutical formulations |
IE127291A IE64274B1 (en) | 1990-04-17 | 1991-04-16 | Pharmaceutical formulations |
HK12495A HK12495A (en) | 1990-04-17 | 1995-01-26 | Pharmaceutical formulations |
SA99191025A SA99191025A (ar) | 1990-04-17 | 1999-02-01 | تراكيب صيدلية |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
IT02005590A IT1246383B (it) | 1990-04-17 | 1990-04-17 | Metodo per il mascheramento del sapore di farmaci |
Publications (3)
Publication Number | Publication Date |
---|---|
IT9020055A0 IT9020055A0 (it) | 1990-04-17 |
IT9020055A1 IT9020055A1 (it) | 1991-10-17 |
IT1246383B true IT1246383B (it) | 1994-11-18 |
Family
ID=11163454
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT02005590A IT1246383B (it) | 1990-04-17 | 1990-04-17 | Metodo per il mascheramento del sapore di farmaci |
Country Status (19)
Country | Link |
---|---|
US (1) | US5409711A (it) |
EP (1) | EP0477333B1 (it) |
JP (1) | JP3193041B2 (it) |
KR (1) | KR0164863B1 (it) |
AT (1) | ATE99927T1 (it) |
AU (1) | AU635133B2 (it) |
CA (1) | CA2058946C (it) |
DE (1) | DE69100991T2 (it) |
DK (1) | DK0477333T3 (it) |
ES (1) | ES2048594T3 (it) |
HK (1) | HK12495A (it) |
IE (1) | IE64274B1 (it) |
IT (1) | IT1246383B (it) |
NZ (1) | NZ237824A (it) |
PT (1) | PT97369B (it) |
RU (1) | RU2085190C1 (it) |
SA (1) | SA99191025A (it) |
WO (1) | WO1991016043A1 (it) |
ZA (1) | ZA912793B (it) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111388444A (zh) * | 2020-03-18 | 2020-07-10 | 北京鑫开元医药科技有限公司 | 一种罗红霉素颗粒及其制备方法 |
Families Citing this family (77)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2704146B1 (fr) * | 1993-04-19 | 1995-07-13 | Cripdom | Microcapsules d'acide acétylsalicylique à libération contrôlée. |
AUPN969796A0 (en) * | 1996-05-07 | 1996-05-30 | F.H. Faulding & Co. Limited | Taste masked liquid suspensions |
US8071128B2 (en) | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
DE19648576C2 (de) * | 1996-11-23 | 1999-08-12 | Lohmann Therapie Syst Lts | Lutschtablette zur modifizierten Freisetzung von Wirkstoffen im Gastrointestinaltrakt |
FR2766089B1 (fr) * | 1997-07-21 | 2000-06-02 | Prographarm Lab | Comprime multiparticulaire perfectionne a delitement rapide |
BR9705470A (pt) * | 1997-11-12 | 1999-07-06 | Ind Quimica E Farmaceutica Sch | Processo para a preparação de uma composição farmaceutica oral composição farmaceutica oral e kit compreendendo uma composição farmacêutica |
NZ333474A (en) * | 1998-01-02 | 1999-06-29 | Mcneil Ppc Inc | A chewable tablet containing ibuprofen, fumaric acid and a non hydrocolloid binder e.g. a wax or a fat |
UA65607C2 (uk) * | 1998-03-04 | 2004-04-15 | Орто-Макнейл Фармацевтикал, Інк. | Фармацевтична композиція (варіанти) та спосіб її приготування |
JP3143433B2 (ja) * | 1998-07-07 | 2001-03-07 | 三基商事株式会社 | マスキング組成物 |
FR2781152B1 (fr) * | 1998-07-20 | 2001-07-06 | Permatec Tech Ag | Utilisation d'un polymere de type acrylique en tant qu'agent de desagregation |
DE19835823A1 (de) * | 1998-08-10 | 1999-10-07 | Lindopharm Gmbh | Pharmazeutische Zusammensetzung, Verfahren zu ihrer Herstellung und ihre Verwendung sowie aus ihr hergestellte wässerige Suspension |
FR2793690B1 (fr) * | 1999-03-30 | 2003-01-03 | Cll Pharma | Formulations pharmaceutiques en macrolides seuls ou associes a d'autres principes actifs et leur utilisation en therapeutique |
BR0009557A (pt) | 1999-04-06 | 2002-05-28 | Ethypharm Lab Prod Ethiques | Suspensão farmacêutica para beber de ibuprofeno |
IN191239B (it) | 1999-06-11 | 2003-10-11 | Ranbaxy Lab Ltd | |
CN1288730A (zh) * | 1999-09-07 | 2001-03-28 | 麦克内尔-Ppc股份有限公司 | 轻泻组合物 |
JP3718398B2 (ja) * | 2000-01-11 | 2005-11-24 | 信越化学工業株式会社 | フィルムコーティング剤及び経口固形製剤 |
US6508954B1 (en) * | 2000-01-18 | 2003-01-21 | Albemarle Corporation | 1,3-dibromo-5,5-dimethylhydantoin of enhanced properties |
US20050049420A1 (en) * | 2000-01-18 | 2005-03-03 | Elnagar Hassan Y. | Process for producing N-halogenated organic compounds |
US7999118B2 (en) * | 2000-01-18 | 2011-08-16 | Albemarle Corporation | Process for producing N-halogenated hydantoins |
CA2401571A1 (en) * | 2000-02-29 | 2001-09-07 | Ilya Avrutov | Processes for preparing clarithromycin and clarithromycin intermediate, essentially oxime-free clarithromycin, and pharmaceutical composition comprising the same |
US20030099715A1 (en) * | 2000-03-28 | 2003-05-29 | Schwarz Franz Xaver | Granulated particles with masked taste |
US6551617B1 (en) | 2000-04-20 | 2003-04-22 | Bristol-Myers Squibb Company | Taste masking coating composition |
DE60128215T2 (de) | 2000-04-20 | 2008-01-10 | Novartis Ag | Beschichtungszusammensetzung zur geschmacksmaskierung |
US7223421B2 (en) * | 2000-06-30 | 2007-05-29 | Mcneil-Ppc, Inc. | Teste masked pharmaceutical particles |
DE60115465T2 (de) | 2000-08-29 | 2006-08-03 | Nobex Corp. | Immunoregulierende verbindungen, deren derivate und ihre verwendung |
CA2359812C (en) * | 2000-11-20 | 2004-02-10 | The Procter & Gamble Company | Pharmaceutical dosage form with multiple coatings for reduced impact of coating fractures |
US20020119196A1 (en) * | 2000-12-21 | 2002-08-29 | Narendra Parikh | Texture masked particles containing an active ingredient |
AU4061702A (en) * | 2001-05-15 | 2003-04-03 | Mcneil-Ppc, Inc. | Dip coating compositions containing starch or dextrin |
US20030070584A1 (en) * | 2001-05-15 | 2003-04-17 | Cynthia Gulian | Dip coating compositions containing cellulose ethers |
US20030077365A1 (en) * | 2001-06-28 | 2003-04-24 | Howarth Jonathan N. | Environmentally-friendly microbiological and microbiocidal control in aqueous systems |
US6919364B2 (en) * | 2001-06-28 | 2005-07-19 | Solution Biosciences, Inc. | Microbiological control in animal processing |
US6986910B2 (en) * | 2001-06-28 | 2006-01-17 | Albemarle Corporation | Microbiological control in poultry processing |
US8048924B2 (en) | 2001-08-29 | 2011-11-01 | Biocon Limited | Methods and compositions employing 4-aminophenylacetic acid compounds |
GB0123400D0 (en) | 2001-09-28 | 2001-11-21 | Novartis Ag | Organic compounds |
US8309118B2 (en) * | 2001-09-28 | 2012-11-13 | Mcneil-Ppc, Inc. | Film forming compositions containing sucralose |
US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
FR2830447B1 (fr) * | 2001-10-09 | 2004-04-16 | Flamel Tech Sa | Forme galenique orale microparticulaire pour la liberation retardee et controlee de principes actifs pharmaceutiques |
US8101209B2 (en) * | 2001-10-09 | 2012-01-24 | Flamel Technologies | Microparticulate oral galenical form for the delayed and controlled release of pharmaceutical active principles |
JP4709486B2 (ja) * | 2001-10-09 | 2011-06-22 | アルベマール・コーポレーシヨン | 産業用水システム中のバイオフィルムの抑制 |
US20030118329A1 (en) * | 2001-12-21 | 2003-06-26 | Pere Obrador | Video indexing using high resolution still images |
JP4619658B2 (ja) * | 2002-03-12 | 2011-01-26 | 富山化学工業株式会社 | 快い味の経口懸濁液および方法 |
WO2003084518A2 (fr) | 2002-04-09 | 2003-10-16 | Flamel Technologies | Suspension orale de microcapsules de principes actifs |
CA2480824A1 (fr) * | 2002-04-09 | 2003-10-16 | Flamel Technologies | Formulation pharmaceutique orale sous forme de suspension aqueuse de microcapsules permettant la liberation modifiee d'amoxicilline |
US6958161B2 (en) * | 2002-04-12 | 2005-10-25 | F H Faulding & Co Limited | Modified release coated drug preparation |
US7429619B2 (en) * | 2002-08-02 | 2008-09-30 | Mcneil Consumer Healthcare | Polyacrylic film forming compositions |
AU2003272601B2 (en) * | 2002-09-20 | 2009-05-07 | Alpharma Pharmaceuticals, Llc | Sustained-release opioid formulations and methods of use |
US20060073216A1 (en) * | 2002-12-26 | 2006-04-06 | Solution Biosciences, Inc. | Compositions and methods for control of bovine mastitis |
US8367111B2 (en) * | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
US20040265446A1 (en) * | 2003-06-24 | 2004-12-30 | Mcnaughton James L. | Microbiocidal control in the processing of poultry |
US7901276B2 (en) | 2003-06-24 | 2011-03-08 | Albemarle Corporation | Microbiocidal control in the processing of meat-producing four-legged animals |
US20040265445A1 (en) * | 2003-06-24 | 2004-12-30 | Liimatta Eric W. | Microbiocidal control in the processing of poultry |
US7632521B2 (en) * | 2003-07-15 | 2009-12-15 | Eurand, Inc. | Controlled release potassium chloride tablets |
US7417037B2 (en) * | 2004-01-20 | 2008-08-26 | The Board Of Regents Of The University Of Oklahoma | Compositions and methods of treatment for inflammatory diseases |
DK1773767T3 (en) | 2004-07-07 | 2016-03-21 | Biocon Ltd | Synthesis of azo bound in immune regulatory relations |
US8747895B2 (en) * | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
GB2419094A (en) | 2004-10-12 | 2006-04-19 | Sandoz Ag | Pharmaceutical composition of unpleasnt tasing active substances |
US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
US20060105039A1 (en) | 2004-10-21 | 2006-05-18 | Jin-Wang Lai | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
US20060105038A1 (en) * | 2004-11-12 | 2006-05-18 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions prepared by coacervation |
US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
JP2007031407A (ja) | 2005-07-29 | 2007-02-08 | Shin Etsu Chem Co Ltd | 低置換度セルロースエーテル含有コーティング用組成物及び不快な味が隠蔽されたフィルムコーティング製剤 |
TWI407913B (zh) * | 2005-12-01 | 2013-09-11 | Albemarle Corp | 加工處理四腳屠宰動物及/或衍生自四腳屠宰動物之生肉品之方法 |
US20070190141A1 (en) * | 2006-02-16 | 2007-08-16 | Aaron Dely | Extended release opiate composition |
WO2008051759A1 (en) | 2006-10-20 | 2008-05-02 | Mcneil-Ppc, Inc. | Acetaminophen / ibuprofen combinations |
AU2007308986A1 (en) * | 2006-10-25 | 2008-05-02 | Mcneil-Ppc, Inc. | Ibuprofen composition |
CN101380474B (zh) * | 2007-09-06 | 2012-07-25 | 北京大学 | 用于口服制剂的pH敏感性固体药物组合物及制备方法 |
KR101704156B1 (ko) * | 2008-11-25 | 2017-02-07 | 미쓰비시 타나베 파마 코퍼레이션 | 구강 내 속붕괴성정을 제조하기 위한 혼합물 |
CA2782285A1 (en) | 2009-12-02 | 2011-06-09 | Luigi Mapelli | Fexofenadine microcapsules and compositions containing them |
WO2011085181A1 (en) * | 2010-01-08 | 2011-07-14 | Eurand, Inc. | Taste masked topiramate composition and an orally disintegrating tablet comprising the same |
EP2719377B1 (en) * | 2011-06-10 | 2018-04-18 | Nipro Corporation | Method for producing orodispersible tablets |
WO2014047001A1 (en) | 2012-09-18 | 2014-03-27 | Mcneil-Ppc, Inc. | Low melting propionic acid derivative particles for use in oral dosage forms |
AU2013318360A1 (en) | 2012-09-18 | 2015-03-26 | Mcneil-Ppc, Inc. | Sustained release oral dosage forms comprising low melting propionic acid derivative particles |
US9820894B2 (en) | 2013-03-22 | 2017-11-21 | The Procter & Gamble Company | Disposable absorbent articles |
EP3288556A4 (en) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
HUE063849T2 (hu) * | 2015-12-28 | 2024-02-28 | Ssp Co Ltd Japan | Tömörített gyógyszerészeti készítmény |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
US10828208B2 (en) | 2016-11-21 | 2020-11-10 | The Procte & Gamble Company | Low-bulk, close-fitting, high-capacity disposable absorbent pant |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2470599A1 (fr) * | 1979-12-07 | 1981-06-12 | Panoz Donald | Perfectionnements apportes aux procedes de preparation de formes galeniques a action retard et a liberation programmee et formes galeniques de medicaments ainsi obtenus |
JPS5858145A (ja) * | 1981-10-05 | 1983-04-06 | Tanabe Seiyaku Co Ltd | 速放性マイクロカプセル |
FR2514261B1 (fr) * | 1981-10-08 | 1986-08-22 | Aec Chim Organ Biolog | Nouvelle composition pour l'enrobage des aliments et des medicaments et granules ainsi enrobes |
US4894240A (en) * | 1983-12-22 | 1990-01-16 | Elan Corporation Plc | Controlled absorption diltiazem formulation for once-daily administration |
DE3440288A1 (de) * | 1984-11-05 | 1986-05-07 | Gergely, Gerhard, Dr.-Ing., Wien | Pharmazeutische zubereitung mit einem gehalt an mindestens einer schleimhautreizenden substanz oder dergleichen, insbesondere profen, sowie verfahren zu ihrer herstellung |
-
1990
- 1990-04-17 IT IT02005590A patent/IT1246383B/it active IP Right Grant
-
1991
- 1991-04-09 AU AU76812/91A patent/AU635133B2/en not_active Expired
- 1991-04-09 KR KR1019910701886A patent/KR0164863B1/ko not_active IP Right Cessation
- 1991-04-09 ES ES91907609T patent/ES2048594T3/es not_active Expired - Lifetime
- 1991-04-09 JP JP50687791A patent/JP3193041B2/ja not_active Expired - Lifetime
- 1991-04-09 CA CA002058946A patent/CA2058946C/en not_active Expired - Fee Related
- 1991-04-09 WO PCT/EP1991/000689 patent/WO1991016043A1/en active IP Right Grant
- 1991-04-09 AT AT91907609T patent/ATE99927T1/de not_active IP Right Cessation
- 1991-04-09 RU SU915010753A patent/RU2085190C1/ru not_active IP Right Cessation
- 1991-04-09 DE DE91907609T patent/DE69100991T2/de not_active Expired - Lifetime
- 1991-04-09 US US07/776,329 patent/US5409711A/en not_active Expired - Lifetime
- 1991-04-09 EP EP91907609A patent/EP0477333B1/en not_active Expired - Lifetime
- 1991-04-09 DK DK91907609.1T patent/DK0477333T3/da active
- 1991-04-15 NZ NZ237824A patent/NZ237824A/en unknown
- 1991-04-15 PT PT97369A patent/PT97369B/pt not_active IP Right Cessation
- 1991-04-15 ZA ZA912793A patent/ZA912793B/xx unknown
- 1991-04-16 IE IE127291A patent/IE64274B1/en not_active IP Right Cessation
-
1995
- 1995-01-26 HK HK12495A patent/HK12495A/xx not_active IP Right Cessation
-
1999
- 1999-02-01 SA SA99191025A patent/SA99191025A/ar unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN111388444A (zh) * | 2020-03-18 | 2020-07-10 | 北京鑫开元医药科技有限公司 | 一种罗红霉素颗粒及其制备方法 |
Also Published As
Publication number | Publication date |
---|---|
JP3193041B2 (ja) | 2001-07-30 |
WO1991016043A1 (en) | 1991-10-31 |
DE69100991D1 (de) | 1994-02-24 |
NZ237824A (en) | 1992-03-26 |
ATE99927T1 (de) | 1994-01-15 |
ES2048594T3 (es) | 1994-03-16 |
IE64274B1 (en) | 1995-07-26 |
US5409711A (en) | 1995-04-25 |
KR0164863B1 (ko) | 1999-01-15 |
DE69100991T2 (de) | 1994-05-05 |
AU7681291A (en) | 1991-11-11 |
EP0477333B1 (en) | 1994-01-12 |
RU2085190C1 (ru) | 1997-07-27 |
IT9020055A0 (it) | 1990-04-17 |
AU635133B2 (en) | 1993-03-11 |
JPH05500674A (ja) | 1993-02-12 |
PT97369A (pt) | 1991-12-31 |
KR920702618A (ko) | 1992-10-06 |
IT9020055A1 (it) | 1991-10-17 |
DK0477333T3 (da) | 1994-03-14 |
HK12495A (en) | 1995-02-03 |
IE911272A1 (en) | 1991-10-23 |
EP0477333A1 (en) | 1992-04-01 |
CA2058946C (en) | 2001-11-20 |
SA99191025A (ar) | 2005-12-03 |
PT97369B (pt) | 1998-08-31 |
ZA912793B (en) | 1992-12-30 |
CA2058946A1 (en) | 1991-10-18 |
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