DE60323138D1 - Kombinationsarzneimittel aus r,r-formoterol und ciclesonide - Google Patents
Kombinationsarzneimittel aus r,r-formoterol und ciclesonideInfo
- Publication number
- DE60323138D1 DE60323138D1 DE60323138T DE60323138T DE60323138D1 DE 60323138 D1 DE60323138 D1 DE 60323138D1 DE 60323138 T DE60323138 T DE 60323138T DE 60323138 T DE60323138 T DE 60323138T DE 60323138 D1 DE60323138 D1 DE 60323138D1
- Authority
- DE
- Germany
- Prior art keywords
- ciclesonide
- formoterol
- combination medicament
- combination
- salt
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- LUKZNWIVRBCLON-GXOBDPJESA-N Ciclesonide Chemical compound C1([C@H]2O[C@@]3([C@H](O2)C[C@@H]2[C@@]3(C[C@H](O)[C@@H]3[C@@]4(C)C=CC(=O)C=C4CC[C@H]32)C)C(=O)COC(=O)C(C)C)CCCCC1 LUKZNWIVRBCLON-GXOBDPJESA-N 0.000 title abstract 2
- 229960003728 ciclesonide Drugs 0.000 title abstract 2
- 239000003814 drug Substances 0.000 title 1
- 229960002848 formoterol Drugs 0.000 title 1
- 150000003839 salts Chemical class 0.000 abstract 2
- BPZSYCZIITTYBL-YJYMSZOUSA-N R-Formoterol Chemical compound C1=CC(OC)=CC=C1C[C@@H](C)NC[C@H](O)C1=CC=C(O)C(NC=O)=C1 BPZSYCZIITTYBL-YJYMSZOUSA-N 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
Landscapes
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Pulmonology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Glass Compositions (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP02027797 | 2002-12-12 | ||
DE10306213 | 2003-02-13 | ||
PCT/EP2003/014045 WO2004052374A1 (en) | 2002-12-12 | 2003-12-11 | Combination medicament |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60323138D1 true DE60323138D1 (de) | 2008-10-02 |
Family
ID=32509778
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60323138T Expired - Lifetime DE60323138D1 (de) | 2002-12-12 | 2003-12-11 | Kombinationsarzneimittel aus r,r-formoterol und ciclesonide |
Country Status (15)
Country | Link |
---|---|
US (2) | US7879833B2 (de) |
EP (1) | EP1572217B1 (de) |
JP (1) | JP4755495B2 (de) |
AT (1) | ATE405275T1 (de) |
AU (1) | AU2003293833B2 (de) |
CA (1) | CA2508692C (de) |
DE (1) | DE60323138D1 (de) |
DK (1) | DK1572217T3 (de) |
ES (1) | ES2312844T3 (de) |
HR (1) | HRP20050611B1 (de) |
IS (1) | IS2597B (de) |
PL (1) | PL375819A1 (de) |
PT (1) | PT1572217E (de) |
RS (1) | RS51707B (de) |
WO (1) | WO2004052374A1 (de) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8025896B2 (en) | 2001-07-16 | 2011-09-27 | Depuy Products, Inc. | Porous extracellular matrix scaffold and method |
GB0312148D0 (en) | 2003-05-28 | 2003-07-02 | Aventis Pharma Ltd | Stabilized pharmaceutical products |
CA2528479A1 (en) | 2003-06-13 | 2004-12-23 | Altana Pharma Ag | Formoterol and ciclesonide combination |
GB0315889D0 (en) | 2003-07-08 | 2003-08-13 | Aventis Pharma Ltd | Stable pharmaceutical products |
CA2538419C (en) | 2003-09-16 | 2012-07-03 | Altana Pharma Ag | Use of ciclesonide for the treatment of respiratory diseases |
EP1796679A1 (de) * | 2004-09-10 | 2007-06-20 | Altana Pharma AG | Ciclesonid- und syk-hemmerverbindung und verfahren zu ihrer verwendung |
WO2011093814A2 (en) * | 2010-01-29 | 2011-08-04 | Mahmut Bilgic | A pharmaceutical combination comprising formoterol and ciclesonide |
BR112013008974A2 (pt) * | 2010-10-12 | 2023-12-19 | Cipla Ltd | Composição farmacêutica, processo para fabricar uma composição farmacêutica e uso de uma composição farmacêutica |
Family Cites Families (79)
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DE3166396D1 (en) * | 1980-02-27 | 1984-11-08 | Tate & Lyle Plc | Crystalline glucose and process for its production |
US4816445A (en) * | 1984-06-21 | 1989-03-28 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Crystalline alpha-maltose |
JP2518646B2 (ja) * | 1987-05-29 | 1996-07-24 | 株式会社 林原生物化学研究所 | マルト−ス粉末の製造方法 |
US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
DE407028T1 (de) | 1989-05-31 | 1994-03-17 | Fisons Plc | Medikament und Inhalationsvorrichtung dafür. |
IL95590A (en) | 1989-09-08 | 1996-06-18 | Glaxo Group Ltd | Medicinal preparations containing Salmetrol and Pluticasone Propionate |
JP3042866B2 (ja) | 1989-09-08 | 2000-05-22 | グラクソ・グループ・リミテッド | 呼吸疾患治療薬 |
SE8903914D0 (sv) | 1989-11-22 | 1989-11-22 | Draco Ab | Oral composition for the treatment of inflammatory bowel diseases |
US6536427B2 (en) * | 1990-03-02 | 2003-03-25 | Glaxo Group Limited | Inhalation device |
US5178866A (en) * | 1990-03-23 | 1993-01-12 | Alza Corporation | Dosage form for delivering drug to the intestine |
EP0540670B1 (de) * | 1990-07-26 | 1996-03-20 | Monsanto Company | Verfahren zur herstellung vernetzter polyamine |
GR1001529B (el) | 1990-09-07 | 1994-03-31 | Elmuquimica Farm Sl | Μέ?οδος για την λήψη νέων 21-εστέρων της 16-17-ακετάλης της πρ να-1,4-διενο-3,20-διόνης. |
US5434304A (en) * | 1990-09-26 | 1995-07-18 | Aktiebolaget Astra | Process for preparing formoterol and related compounds |
AU650953B2 (en) | 1991-03-21 | 1994-07-07 | Novartis Ag | Inhaler |
US5795564A (en) * | 1991-04-05 | 1998-08-18 | Sepracor, Inc. | Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol |
US6866839B2 (en) * | 1991-04-05 | 2005-03-15 | Sepracor Inc. | Methods and compositions for treating pulmonary disorders using optically pure (R,R)-formoterol |
PT656207E (pt) * | 1991-06-10 | 2001-11-30 | Schering Corp | Formulacoes de aerossois sem clorofluorocarbonetos |
IT1250691B (it) * | 1991-07-22 | 1995-04-21 | Giancarlo Santus | Composizioni terapeutiche per somministrazione intranasale comprendenti ketorolac. |
ATE213946T1 (de) | 1991-12-18 | 2002-03-15 | Formoterol und budesonide enthaltende zusammensetzung | |
GB9213874D0 (en) | 1992-06-30 | 1992-08-12 | Fisons Plc | Process to novel medicament form |
GB9306703D0 (en) | 1993-03-31 | 1993-05-26 | Fisons Plc | Inhalation device |
NZ265054A (en) | 1993-04-02 | 1997-08-22 | Byk Gulden Lomberg Chem Fab | 16-hydroxy prednisolone cyclohexanecarboxaldehyde acetal derivatives |
IL111194A (en) | 1993-10-08 | 1998-02-08 | Fisons Plc | Process for the production of drug patramulations |
DE19541689A1 (de) * | 1994-11-14 | 1996-05-15 | Byk Gulden Lomberg Chem Fab | Kombinationsarzneimittel |
US5811388A (en) * | 1995-06-07 | 1998-09-22 | Cibus Pharmaceutical, Inc. | Delivery of drugs to the lower GI tract |
US6136839A (en) * | 1995-06-12 | 2000-10-24 | G. D. Searle & Co. | Treatment of inflammation and inflammation-related disorders with a combination of a cyclooxygenase-2 inhibitor and a 5-lipoxygenase inhibitor |
WO1997011705A1 (en) * | 1995-09-26 | 1997-04-03 | Takeda Chemical Industries, Ltd. | Phosphorylamides, their preparation and use |
DE19635498A1 (de) | 1996-09-03 | 1998-03-26 | Byk Gulden Lomberg Chem Fab | Verfahren zur Epimerenanreicherung |
SE9603725D0 (sv) | 1996-10-11 | 1996-10-11 | Astra Ab | New teatment |
US6380222B2 (en) * | 1996-10-11 | 2002-04-30 | Astrazeneca Ab | Use of an H+, K+-atpase inhibitor in the treatment of nasal polyps |
FR2754712B1 (fr) * | 1996-10-17 | 1999-09-03 | Merck Sharp Dohme Chibret Lab | Compositions ophtalmiques |
ES2178015T3 (es) | 1996-11-11 | 2002-12-16 | Sepracor Inc | Procedimiento de preparacion de isomeros de formoterol opticamente puros. |
US6040344A (en) | 1996-11-11 | 2000-03-21 | Sepracor Inc. | Formoterol process |
US6613795B2 (en) * | 1996-11-11 | 2003-09-02 | Christian Noe | Enantiomerically pure basic arylcycloalkylhydroxycarboxylic esters, processes for their preparation and their use in medicaments |
SE9700135D0 (sv) * | 1997-01-20 | 1997-01-20 | Astra Ab | New formulation |
US20020111495A1 (en) * | 1997-04-04 | 2002-08-15 | Pfizer Inc. | Nicotinamide acids, amides, and their mimetics active as inhibitors of PDE4 isozymes |
US6120752A (en) | 1997-05-21 | 2000-09-19 | 3M Innovative Properties Company | Medicinal aerosol products containing formulations of ciclesonide and related steroids |
GB2329939A (en) * | 1997-06-26 | 1999-04-07 | Glaxo Group Ltd | Self-lubricating valve stem for aerosol containers |
US6470894B2 (en) | 1997-09-19 | 2002-10-29 | Thione International, Inc. | Glutathione, green tea, grape seed extract to neutralize tobacco free radicals |
ATE215820T1 (de) | 1997-10-08 | 2002-04-15 | Sepracor Inc | Dosierungsform zur verabreichung von aerosolen |
SE9704186D0 (sv) | 1997-11-14 | 1997-11-14 | Astra Ab | New composition of matter |
DE69839735D1 (de) * | 1997-12-15 | 2008-08-28 | Astellas Pharma Inc | Pyrimidin-5-carboxamid-derivate |
SE9801368D0 (sv) | 1998-04-20 | 1998-04-20 | Astra Ab | New use |
TWI243687B (en) * | 1998-04-21 | 2005-11-21 | Teijin Ltd | Pharmaceutical composition for application to mucosa |
US6241969B1 (en) * | 1998-06-26 | 2001-06-05 | Elan Corporation Plc | Aqueous compositions containing corticosteroids for nasal and pulmonary delivery |
ATE283033T1 (de) * | 1998-07-24 | 2004-12-15 | Jago Res Ag | Medizinische aerosolformulierungen |
EP1102579B1 (de) * | 1998-08-04 | 2003-03-19 | Jago Research Ag | Medizinische aerosolformulierungen |
PL193616B1 (pl) | 1998-09-23 | 2007-02-28 | Altana Pharma Ag | Tetrahydropirydoetery |
PT1283036E (pt) * | 1998-11-13 | 2008-03-06 | Jagotec Ag | Inalador de pó seco de dose múltipla com um reservatório de pó |
US6352152B1 (en) | 1998-12-18 | 2002-03-05 | Smithkline Beecham Corporation | Method and package for storing a pressurized container containing a drug |
US6124268A (en) * | 1999-02-17 | 2000-09-26 | Natreon Inc. | Natural antioxidant compositions, method for obtaining same and cosmetic, pharmaceutical and nutritional formulations thereof |
JP2001048807A (ja) | 1999-08-04 | 2001-02-20 | Wakamoto Pharmaceut Co Ltd | 難溶性薬物を水に溶解してなる製剤 |
DE19947234A1 (de) | 1999-09-30 | 2001-04-05 | Asta Medica Ag | Neue Kombination von Loteprednol und Antihistaminika |
AR026073A1 (es) | 1999-10-20 | 2002-12-26 | Nycomed Gmbh | Composicion farmaceutica acuosa que contiene ciclesonida |
AR026072A1 (es) * | 1999-10-20 | 2002-12-26 | Nycomed Gmbh | Composicion farmaceutica que contiene ciclesonida para aplicacion a la mucosa |
GB0002336D0 (en) | 2000-02-01 | 2000-03-22 | Glaxo Group Ltd | Medicaments |
GB0009607D0 (en) | 2000-04-18 | 2000-06-07 | Glaxo Group Ltd | Medical compositions |
GB0012261D0 (en) | 2000-05-19 | 2000-07-12 | Astrazeneca Ab | Novel process |
GB0015043D0 (en) | 2000-06-21 | 2000-08-09 | Glaxo Group Ltd | Medicament dispenser |
FI20002177A0 (fi) | 2000-10-02 | 2000-10-02 | Orion Yhtymae Oyj | Uusi yhdistelmä astman hoitoon |
DE10062712A1 (de) * | 2000-12-15 | 2002-06-20 | Boehringer Ingelheim Pharma | Neue Arzneimittelkompositionen auf der Basis von Anticholinergika und Corticosteroiden |
US20020183292A1 (en) * | 2000-10-31 | 2002-12-05 | Michel Pairet | Pharmaceutical compositions based on anticholinergics and corticosteroids |
WO2002038155A1 (en) * | 2000-11-07 | 2002-05-16 | Merck & Co., Inc. | Method of treatment with a combination of a pde4 inhibitor and a leukotriene antagonist |
IL156308A0 (en) * | 2000-12-22 | 2004-01-04 | Glaxo Group Ltd | Metered dose inhaler for salmeterol xinafoate |
ES2291452T3 (es) * | 2001-02-06 | 2008-03-01 | Innovata Biomed Limited | Formulacion bimodal de polvo seco para inhalacion. |
US20030055026A1 (en) * | 2001-04-17 | 2003-03-20 | Dey L.P. | Formoterol/steroid bronchodilating compositions and methods of use thereof |
WO2003006310A1 (fr) | 2001-07-13 | 2003-01-23 | Tfe Techniques Et Fabrications Electroniques | Dispositif destine a indiquer acoustiquement a un plongeur equipe d'un scaphandre la pression de gaz de respiration dans le reservoir et/ou la pression hydrostatique |
CA2464250C (en) * | 2001-10-24 | 2008-08-05 | Frank-Christophe Lintz | Kit for the preparation of a pharmaceutical composition |
EP1453743B1 (de) * | 2001-11-17 | 2008-07-23 | Aventis Pharma Limited | Pharmazeutisches produkt und verfahren mit adsorber |
CA2467652A1 (en) * | 2001-11-19 | 2003-05-30 | Altana Pharma Ag | Reversible proton pump inhibitors for the treatment of airway disorders |
GB0207899D0 (en) * | 2002-04-05 | 2002-05-15 | 3M Innovative Properties Co | Formoterol and cielesonide aerosol formulations |
ITMI20020808A1 (it) * | 2002-04-17 | 2003-10-17 | Chiesi Farma Spa | Procedimento per la preparazione di una sospensione sterile di particelle di beclometasone dipropionato da somministrare per inalazione |
BRPI0312377A8 (pt) * | 2002-07-02 | 2015-12-15 | Altana Pharma Ag | Suspensão aquosa estéril contendo ciclesonida |
PL373433A1 (en) * | 2002-08-30 | 2005-08-22 | Altana Pharma Ag | The use of the combination of ciclesonide and antihistamines for the treatment of allergic rhinitis |
CA2525943A1 (en) | 2003-05-22 | 2004-12-02 | Altana Pharma Ag | Salmeterol and ciclesonide combination |
GB0312148D0 (en) | 2003-05-28 | 2003-07-02 | Aventis Pharma Ltd | Stabilized pharmaceutical products |
CA2528479A1 (en) | 2003-06-13 | 2004-12-23 | Altana Pharma Ag | Formoterol and ciclesonide combination |
GB0315889D0 (en) | 2003-07-08 | 2003-08-13 | Aventis Pharma Ltd | Stable pharmaceutical products |
CA2538419C (en) * | 2003-09-16 | 2012-07-03 | Altana Pharma Ag | Use of ciclesonide for the treatment of respiratory diseases |
-
2003
- 2003-12-11 AT AT03789217T patent/ATE405275T1/de active
- 2003-12-11 PL PL03375819A patent/PL375819A1/xx not_active Application Discontinuation
- 2003-12-11 CA CA2508692A patent/CA2508692C/en not_active Expired - Fee Related
- 2003-12-11 WO PCT/EP2003/014045 patent/WO2004052374A1/en active IP Right Grant
- 2003-12-11 PT PT03789217T patent/PT1572217E/pt unknown
- 2003-12-11 AU AU2003293833A patent/AU2003293833B2/en not_active Expired
- 2003-12-11 US US10/537,356 patent/US7879833B2/en active Active
- 2003-12-11 JP JP2005502319A patent/JP4755495B2/ja not_active Expired - Lifetime
- 2003-12-11 DE DE60323138T patent/DE60323138D1/de not_active Expired - Lifetime
- 2003-12-11 DK DK03789217T patent/DK1572217T3/da active
- 2003-12-11 RS YU20050429A patent/RS51707B/sr unknown
- 2003-12-11 ES ES03789217T patent/ES2312844T3/es not_active Expired - Lifetime
- 2003-12-11 EP EP03789217A patent/EP1572217B1/de not_active Expired - Lifetime
-
2005
- 2005-06-23 IS IS7910A patent/IS2597B/is unknown
- 2005-07-01 HR HRP20050611AA patent/HRP20050611B1/hr not_active IP Right Cessation
-
2010
- 2010-12-20 US US12/973,350 patent/US8258124B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
EP1572217A1 (de) | 2005-09-14 |
IS7910A (is) | 2005-06-23 |
JP2006514686A (ja) | 2006-05-11 |
CA2508692A1 (en) | 2004-06-24 |
HRP20050611B1 (hr) | 2013-12-20 |
HRP20050611A2 (en) | 2006-09-30 |
DK1572217T3 (da) | 2008-12-15 |
ES2312844T3 (es) | 2009-03-01 |
PT1572217E (pt) | 2008-11-28 |
PL375819A1 (en) | 2005-12-12 |
US20060025392A1 (en) | 2006-02-02 |
US7879833B2 (en) | 2011-02-01 |
US8258124B2 (en) | 2012-09-04 |
IS2597B (is) | 2010-03-15 |
EP1572217B1 (de) | 2008-08-20 |
RS20050429A (en) | 2007-12-31 |
CA2508692C (en) | 2012-04-03 |
ATE405275T1 (de) | 2008-09-15 |
US20110086827A1 (en) | 2011-04-14 |
JP4755495B2 (ja) | 2011-08-24 |
AU2003293833B2 (en) | 2009-10-01 |
RS51707B (sr) | 2011-10-31 |
AU2003293833A1 (en) | 2004-06-30 |
WO2004052374A1 (en) | 2004-06-24 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |