DE69637534D1 - Verfahren zur herstellung einer undifferenzierten zell - Google Patents

Verfahren zur herstellung einer undifferenzierten zell

Info

Publication number
DE69637534D1
DE69637534D1 DE69637534T DE69637534T DE69637534D1 DE 69637534 D1 DE69637534 D1 DE 69637534D1 DE 69637534 T DE69637534 T DE 69637534T DE 69637534 T DE69637534 T DE 69637534T DE 69637534 D1 DE69637534 D1 DE 69637534D1
Authority
DE
Germany
Prior art keywords
undifferenced
cell
producing
undifferenced cell
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69637534T
Other languages
English (en)
Inventor
Ilham Mohamed Abuljadayel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Tristem Trading Cyprus Ltd
Original Assignee
Tristem Trading Cyprus Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Tristem Trading Cyprus Ltd filed Critical Tristem Trading Cyprus Ltd
Application granted granted Critical
Publication of DE69637534D1 publication Critical patent/DE69637534D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0634—Cells from the blood or the immune system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/06—Anti-neoplasic drugs, anti-retroviral drugs, e.g. azacytidine, cyclophosphamide
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/50—Cell markers; Cell surface determinants
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/11—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from blood or immune system cells

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biomedical Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Cell Biology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69637534T 1995-02-02 1996-01-31 Verfahren zur herstellung einer undifferenzierten zell Expired - Lifetime DE69637534D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GBGB9502022.8A GB9502022D0 (en) 1995-02-02 1995-02-02 A method for preparing lymphohaematopoietic progenitor cells
PCT/GB1996/000208 WO1996023870A1 (en) 1995-02-02 1996-01-31 A method of preparing an undifferentiated cell

Publications (1)

Publication Number Publication Date
DE69637534D1 true DE69637534D1 (de) 2008-07-03

Family

ID=10768971

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69637534T Expired - Lifetime DE69637534D1 (de) 1995-02-02 1996-01-31 Verfahren zur herstellung einer undifferenzierten zell

Country Status (23)

Country Link
US (3) US6090625A (de)
EP (1) EP0807166B1 (de)
JP (4) JPH10513053A (de)
KR (1) KR100630591B1 (de)
CN (1) CN1289660C (de)
AP (1) AP693A (de)
AT (1) ATE396253T1 (de)
AU (1) AU4545196A (de)
BR (1) BR9606866A (de)
CA (1) CA2211147C (de)
CY (1) CY2206B1 (de)
DE (1) DE69637534D1 (de)
DK (1) DK0807166T3 (de)
ES (1) ES2308774T3 (de)
GB (1) GB9502022D0 (de)
HK (1) HK1017710A1 (de)
IL (2) IL139244A (de)
NZ (1) NZ300650A (de)
PT (1) PT807166E (de)
RU (2) RU2177996C2 (de)
SI (1) SI0807166T1 (de)
WO (1) WO1996023870A1 (de)
ZA (1) ZA96727B (de)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9502022D0 (en) * 1995-02-02 1995-03-22 Abuljadayel Ilham M S A method for preparing lymphohaematopoietic progenitor cells
US9068164B1 (en) 1995-02-02 2015-06-30 Tristem Trading (Cyprus) Limited Method of preparing an undifferentiated cell
US10638734B2 (en) 2004-01-05 2020-05-05 Abt Holding Company Multipotent adult stem cells, sources thereof, methods of obtaining and maintaining same, methods of differentiation thereof, methods of use thereof and cells derived thereof
US8252280B1 (en) 1999-08-05 2012-08-28 Regents Of The University Of Minnesota MAPC generation of muscle
US7015037B1 (en) * 1999-08-05 2006-03-21 Regents Of The University Of Minnesota Multiponent adult stem cells and methods for isolation
US8075881B2 (en) 1999-08-05 2011-12-13 Regents Of The University Of Minnesota Use of multipotent adult stem cells in treatment of myocardial infarction and congestive heart failure
US8609412B2 (en) 1999-08-05 2013-12-17 Regents Of The University Of Minnesota Mapc generation of lung tissue
EP1226233B1 (de) 1999-08-05 2011-06-29 ABT Holding Company Multipotente erwachsene stammzellen und verfahren zu deren isolierung
US7927587B2 (en) * 1999-08-05 2011-04-19 Regents Of The University Of Minnesota MAPC administration for the treatment of lysosomal storage disorders
CN101538551A (zh) * 2000-05-10 2009-09-23 特里施泰姆贸易(塞浦路斯)有限公司 一种设备
NL1017973C2 (nl) * 2000-05-10 2002-11-08 Tristem Trading Cyprus Ltd Inrichting.
EP1491093B1 (de) * 2001-02-14 2013-07-31 ABT Holding Company Multipotente adulte Stammzellen, ausgangsmaterial dafür, verfahren zu ihrer Gewinnung und Erhaltung, Differenzierungsmethoden dafür, verfahren zu ihrer Verwendung, sowie von ihnen stammende Zellen
DE10144326B4 (de) * 2001-09-10 2005-09-22 Siemens Ag Verfahren und System zur Überwachung eines Reifenluftdrucks
TWI288779B (en) * 2002-03-28 2007-10-21 Blasticon Biotech Forschung Dedifferentiated, programmable stem cells of monocytic origin, and their production and use
DE10231655A1 (de) * 2002-07-12 2004-02-26 Blasticon Biotechnologische Forschung Gmbh Transplantat-Akzeptanz induzierende Zellen monozytären Ursprungs, sowie deren Herstellung und Verwendung
US20060228798A1 (en) 2002-11-27 2006-10-12 Catherine Verfaillie Homologous recombination in multipotent adult progenitor cells
KR20060040671A (ko) * 2003-07-11 2006-05-10 블라스티콘 바이오테크놀로지셰 포르슝 게엠베하 단구성 기원의 자기 유래 자가 관용성 유도 세포 및약제학적 제제에 있어서의 이의 용도
CA2533124C (en) * 2003-08-12 2014-01-28 Tigenix N.V. Use of cxcl6 chemokine in the prevention or repair of cartilage defects
JP2007513188A (ja) 2003-12-04 2007-05-24 リージェンツ オブ ザ ユニバーシティ オブ ミネソタ リソソーム蓄積症の処置のための組成物および方法
WO2006047743A2 (en) 2004-10-26 2006-05-04 Regents Of The University Of Minnesota Swine multipotent adult progenitor cells
US20090104159A1 (en) * 2005-02-10 2009-04-23 Felipe Prosper Vascular/Lymphatic Endothelial Cells
AU2005331534B2 (en) * 2005-05-05 2011-12-08 Regents Of The University Of Minnesota Use of MAPC or progeny therefrom to populate lymphohematopoietic tissues
US20080317740A1 (en) * 2005-05-05 2008-12-25 Bruce Blazar Use of Nk Cell Inhibition to Facilitate Persistence of Engrafted Mhc-I-Negative Cells
US20080194024A1 (en) * 2005-07-29 2008-08-14 Mays Robert W Culture of Non-Embryonic Cells at High Cell Density
WO2007047509A2 (en) 2005-10-14 2007-04-26 Regents Of The University Of Minnesota Differentiation of non-embryonic stem cells to cells having a pancreatic phenotype
CA2670497A1 (en) 2006-11-24 2008-05-29 Regents Of The University Of Minnesota Endodermal progenitor cells
WO2009092092A1 (en) 2008-01-18 2009-07-23 Regents Of The University Of Minnesota Stem cell aggregates and methods for making and using
WO2010049752A1 (en) 2008-10-31 2010-05-06 Katholieke Universiteit Leuven Optimized methods for differentiation of cells into cells with hepatocyte and hepatocyte progenitor phenotypes, cells produced by the methods, and methods for using the cells
CA2952805C (en) 2009-06-05 2021-06-01 Cellular Dynamics International, Inc. Reprogramming t cells and hematopoietic cells
BR112012001329B1 (pt) * 2009-07-21 2021-04-13 Abt Holding Company Uso de células progenitoras adultas multipotentes (mapcs), e, métodos para obter células progenitoras adultas multipotentes (mapcs) com uma potência desejada e para aumentar a potência de células progenitoras adultas multipotentes (mapcs)
WO2011011477A1 (en) * 2009-07-21 2011-01-27 Abt Holding Company Use of stem cells to reduce leukocyte extravasation
WO2011034073A1 (ja) * 2009-09-15 2011-03-24 国立大学法人東京大学 分化細胞の新規製造法
CN102647989A (zh) * 2009-10-19 2012-08-22 特里施泰姆贸易(塞浦路斯)有限公司 采用重编程序的成熟成体细胞的治疗
US20110206647A1 (en) * 2010-02-25 2011-08-25 Abt Holding Company Modulation of Angiogenesis
WO2011106476A1 (en) * 2010-02-25 2011-09-01 Abt Holding Company Modulation of microglia activation
US8774488B2 (en) 2010-03-11 2014-07-08 Cellscape Corporation Method and device for identification of nucleated red blood cells from a maternal blood sample
SG10201913920PA (en) 2010-05-12 2020-03-30 Abt Holding Co Modulation of splenocytes in cell therapy
WO2011158125A2 (en) 2010-06-17 2011-12-22 Katholieke Universiteit Leuven Methods for differentiating cells into hepatic stellate cells and hepatic sinusoidal endothelial cells, cells produced by the methods, and methods for using the cells
AU2011293440B2 (en) 2010-08-24 2016-05-05 Katholieke Universiteit Leuven Non-static suspension culture of cell aggregates
SG11201407768QA (en) * 2012-04-24 2015-01-29 Brigham & Womens Hospital Generating pluripotent cells de novo
RU2497947C1 (ru) * 2012-08-15 2013-11-10 Государственное бюджетное образовательное учреждение высшего профессионального образования "Сибирский государственный медицинский университет" Министерства зравоохранения и социального развития Российской Федерации (ГБОУ ВПО СибГМУ Минздравсоцразвития России) Способ модификации моноцитов периферической крови для повышения их паракринной активности при аутологической трансплантации
SG11201508403XA (en) 2013-04-12 2015-11-27 Saverio Lafrancesca Improving organs for transplantation
NZ745530A (en) 2016-01-21 2023-03-31 Abt Holding Co Stem cells for wound healing
JP2017008049A (ja) * 2016-07-04 2017-01-12 トライステム・トレイディング・（キプロス）・リミテッドＴｒｉＳｔｅｍ Ｔｒａｄｉｎｇ （Ｃｙｐｒｕｓ） Ｌｉｍｉｔｅｄ 再プログラム化成熟成体細胞を用いる治療
US20220125852A1 (en) * 2020-10-27 2022-04-28 Therapeutic Solutions International, Inc. Protection and regeneration of neurological function by using stem cells

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5004681B1 (en) * 1987-11-12 2000-04-11 Biocyte Corp Preservation of fetal and neonatal hematopoietic stem and progenitor cells of the blood
US5061620A (en) * 1990-03-30 1991-10-29 Systemix, Inc. Human hematopoietic stem cell
US6194376B1 (en) * 1991-03-11 2001-02-27 Creative Biomolecules, Inc. Method for modulating inflammatory response comprising administering morphogen
US5199942A (en) * 1991-06-07 1993-04-06 Immunex Corporation Method for improving autologous transplantation
CA2121370C (en) * 1991-11-22 2003-03-18 David H. Sachs Specific tolerance in transplantation
AU4402193A (en) * 1992-06-08 1994-01-04 Becton Dickinson & Company Human primitive stem cells
DE4240635C2 (de) * 1992-12-03 1997-07-10 Lothar Prof Dr Kanz Vermehrung hämatopoetischer Vorläuferzellen ex vivo sowieZusammensetzungen hämatopoetischer Wachstumsfaktoren
US5654186A (en) * 1993-02-26 1997-08-05 The Picower Institute For Medical Research Blood-borne mesenchymal cells
US5843780A (en) * 1995-01-20 1998-12-01 Wisconsin Alumni Research Foundation Primate embryonic stem cells
GB9502022D0 (en) * 1995-02-02 1995-03-22 Abuljadayel Ilham M S A method for preparing lymphohaematopoietic progenitor cells
US5877299A (en) * 1995-06-16 1999-03-02 Stemcell Technologies Inc. Methods for preparing enriched human hematopoietic cell preparations
US5843633A (en) * 1996-04-26 1998-12-01 Amcell Corporation Characterization of a human hematopoietic progenitor cell antigen
US6227202B1 (en) * 1996-09-03 2001-05-08 Maulana Azad Medical College Method of organogenesis and tissue regeneration/repair using surgical techniques
US6468794B1 (en) * 1999-02-12 2002-10-22 Stemcells, Inc. Enriched central nervous system stem cell and progenitor cell populations, and methods for identifying, isolating and enriching for such populations
TWI288779B (en) * 2002-03-28 2007-10-21 Blasticon Biotech Forschung Dedifferentiated, programmable stem cells of monocytic origin, and their production and use

Also Published As

Publication number Publication date
MX9705919A (es) 1997-10-31
PT807166E (pt) 2008-08-27
KR100630591B1 (ko) 2007-04-11
JP2007259868A (ja) 2007-10-11
ATE396253T1 (de) 2008-06-15
BR9606866A (pt) 1997-12-23
IL139244A (en) 2006-10-05
SI0807166T1 (sl) 2008-12-31
AP693A (en) 1998-11-11
ZA96727B (en) 1996-08-16
AU4545196A (en) 1996-08-21
RU2177996C2 (ru) 2002-01-10
AP9701031A0 (en) 1997-07-31
CY2206B1 (en) 2002-11-08
CA2211147A1 (en) 1996-08-08
CN1289660C (zh) 2006-12-13
RU2215539C2 (ru) 2003-11-10
CN1180374A (zh) 1998-04-29
EP0807166B1 (de) 2008-05-21
US20020076812A1 (en) 2002-06-20
ES2308774T3 (es) 2008-12-01
JP2012040011A (ja) 2012-03-01
EP0807166A1 (de) 1997-11-19
JP2009148266A (ja) 2009-07-09
US20110143431A1 (en) 2011-06-16
GB9502022D0 (en) 1995-03-22
JPH10513053A (ja) 1998-12-15
US6090625A (en) 2000-07-18
DK0807166T3 (da) 2008-09-22
NZ300650A (en) 1999-04-29
HK1017710A1 (en) 1999-11-26
CA2211147C (en) 2012-01-17
IL116994A (en) 2001-01-11
WO1996023870A1 (en) 1996-08-08
KR19980701949A (ko) 1998-06-25

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