DE69616651D1 - Antiidiotypische Antikörper die eine Immunantwort gegen den Rezeptor für epidermalen Wachstumsfaktor induzieren - Google Patents

Antiidiotypische Antikörper die eine Immunantwort gegen den Rezeptor für epidermalen Wachstumsfaktor induzieren

Info

Publication number
DE69616651D1
DE69616651D1 DE69616651T DE69616651T DE69616651D1 DE 69616651 D1 DE69616651 D1 DE 69616651D1 DE 69616651 T DE69616651 T DE 69616651T DE 69616651 T DE69616651 T DE 69616651T DE 69616651 D1 DE69616651 D1 DE 69616651D1
Authority
DE
Germany
Prior art keywords
induce
growth factor
immune response
epidermal growth
response against
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69616651T
Other languages
English (en)
Inventor
Ana Carceller
Elisabet Rosell
Alicia Gomez
Jaume Adan
Jaume Piulats
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck Patent GmbH
Original Assignee
Merck Patent GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck Patent GmbH filed Critical Merck Patent GmbH
Application granted granted Critical
Publication of DE69616651D1 publication Critical patent/DE69616651D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2863—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for growth factors, growth regulators
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/42—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins
    • C07K16/4208—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig
    • C07K16/4241—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig
    • C07K16/4258—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against immunoglobulins against an idiotypic determinant on Ig against anti-human or anti-animal Ig against anti-receptor Ig
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/505—Medicinal preparations containing antigens or antibodies comprising antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
DE69616651T 1995-05-26 1996-05-14 Antiidiotypische Antikörper die eine Immunantwort gegen den Rezeptor für epidermalen Wachstumsfaktor induzieren Expired - Lifetime DE69616651D1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP95107967 1995-05-26

Publications (1)

Publication Number Publication Date
DE69616651D1 true DE69616651D1 (de) 2001-12-13

Family

ID=8219291

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69616651T Expired - Lifetime DE69616651D1 (de) 1995-05-26 1996-05-14 Antiidiotypische Antikörper die eine Immunantwort gegen den Rezeptor für epidermalen Wachstumsfaktor induzieren

Country Status (15)

Country Link
US (1) US5969107A (de)
JP (1) JPH08325299A (de)
KR (1) KR960040375A (de)
CN (1) CN1142505A (de)
AT (1) ATE208403T1 (de)
AU (1) AU710159B2 (de)
CA (1) CA2177328A1 (de)
CZ (1) CZ289357B6 (de)
DE (1) DE69616651D1 (de)
HU (1) HUP9601392A3 (de)
MX (1) MX9601930A (de)
NO (1) NO962125L (de)
PL (1) PL314414A1 (de)
SK (1) SK67496A3 (de)
ZA (1) ZA964207B (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6924359B1 (en) * 1999-07-01 2005-08-02 Yale University Neovascular-targeted immunoconjugates
EP1358318B8 (de) * 2001-02-07 2006-11-15 Wilex AG Hybridomzelllinie g250 und deren verwendung zur herstellung monoklonaler antikörper
AU2003241398A1 (en) * 2002-05-06 2003-11-17 Washington University Methods of treatment of glaucoma and other conditions mediated by nos-2 expression via inhibition of the egfr pathway
AU2004259398A1 (en) 2003-06-27 2005-02-03 Amgen Fremont Inc. Antibodies directed to the deletion mutants of epidermal growth factor receptor and uses thereof
WO2008077171A1 (en) * 2006-12-22 2008-07-03 Novelix Therapeutics Gmbh Treatment of diabetes by at least one epidermal growth factor receptor specific antibody or a derivative thereof
US20130059793A1 (en) * 2010-02-08 2013-03-07 Board Of Regents, The University Of Texas System Egf receptor mimicking peptides
ES2865068T3 (es) 2011-01-14 2021-10-14 Univ California Anticuerpos terapéuticos contra la proteína ROR-1 y métodos para usarlos
CN109306010B (zh) * 2017-07-26 2022-07-19 石家庄以岭药业股份有限公司 表皮生长因子受体抗体及其用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE45285T1 (de) * 1983-11-07 1989-08-15 Wistar Inst Durch antiidiotype antikoerper induzierte immune antwort zu tumoren und viren.
US4699880A (en) * 1984-09-25 1987-10-13 Immunomedics, Inc. Method of producing monoclonal anti-idiotype antibody
US4918164A (en) * 1987-09-10 1990-04-17 Oncogen Tumor immunotherapy using anti-idiotypic antibodies
US5459061A (en) * 1990-01-26 1995-10-17 W. Alton Jones Cell Science Center, Inc. Hybridomas producing monoclonal antibodies which specifically bind to continuous epitope on the human EGF receptor and compete with EGF for binding to the EGF receptor
CZ282603B6 (cs) * 1991-03-06 1997-08-13 Merck Patent Gesellschaft Mit Beschränkter Haftun G Humanizované a chimerické monoklonální protilátky
US5344760A (en) * 1991-06-03 1994-09-06 Ciba Corning Diagnostics Corp. Method of cancer detection
ES2144440T3 (es) * 1992-08-18 2000-06-16 Centro Inmunologia Molecular Anticuerpos monoclonales que reconocen el receptor del factor de crecimiento epidermico, celulas y metodos para su produccion y compuestos que los contienen.

Also Published As

Publication number Publication date
ATE208403T1 (de) 2001-11-15
CA2177328A1 (en) 1996-11-27
SK67496A3 (en) 1996-12-04
CN1142505A (zh) 1997-02-12
HUP9601392A3 (en) 2000-08-28
AU710159B2 (en) 1999-09-16
CZ152596A3 (en) 1996-12-11
NO962125D0 (no) 1996-05-24
JPH08325299A (ja) 1996-12-10
ZA964207B (en) 1996-12-04
US5969107A (en) 1999-10-19
AU5242296A (en) 1996-12-05
CZ289357B6 (cs) 2002-01-16
PL314414A1 (en) 1996-12-09
NO962125L (no) 1996-11-27
HU9601392D0 (en) 1996-07-29
KR960040375A (ko) 1996-12-17
HUP9601392A2 (en) 1997-03-28
MX9601930A (es) 1997-01-31

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Legal Events

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