DE69612835T2 - Tricyclische verbindungen - Google Patents
Tricyclische verbindungenInfo
- Publication number
- DE69612835T2 DE69612835T2 DE69612835T DE69612835T DE69612835T2 DE 69612835 T2 DE69612835 T2 DE 69612835T2 DE 69612835 T DE69612835 T DE 69612835T DE 69612835 T DE69612835 T DE 69612835T DE 69612835 T2 DE69612835 T2 DE 69612835T2
- Authority
- DE
- Germany
- Prior art keywords
- tricyclic
- connections
- hydrogen
- ch2o
- chem
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
- C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
- C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
- C07C235/16—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
- C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
- C07D221/04—Ortho- or peri-condensed ring systems
- C07D221/06—Ring systems of three rings
- C07D221/16—Ring systems of three rings containing carbocyclic rings other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D307/93—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems condensed with a ring other than six-membered
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D313/00—Heterocyclic compounds containing rings of more than six members having one oxygen atom as the only ring hetero atom
- C07D313/02—Seven-membered rings
- C07D313/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D313/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D313/12—[b,e]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D333/78—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems condensed with rings other than six-membered or with ring systems containing such rings
- C07D333/80—Seven-membered rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D337/00—Heterocyclic compounds containing rings of more than six members having one sulfur atom as the only ring hetero atom
- C07D337/02—Seven-membered rings
- C07D337/06—Seven-membered rings condensed with carbocyclic rings or ring systems
- C07D337/10—Seven-membered rings condensed with carbocyclic rings or ring systems condensed with two six-membered rings
- C07D337/12—[b,e]-condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/02—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains two hetero rings
- C07D493/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/16—Benz[e]indenes; Hydrogenated benz[e]indenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/06—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members
- C07C2603/10—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings
- C07C2603/12—Ortho- or ortho- and peri-condensed systems containing three rings containing at least one ring with less than six ring members containing five-membered rings only one five-membered ring
- C07C2603/18—Fluorenes; Hydrogenated fluorenes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2603/00—Systems containing at least three condensed rings
- C07C2603/02—Ortho- or ortho- and peri-condensed systems
- C07C2603/04—Ortho- or ortho- and peri-condensed systems containing three rings
- C07C2603/30—Ortho- or ortho- and peri-condensed systems containing three rings containing seven-membered rings
- C07C2603/32—Dibenzocycloheptenes; Hydrogenated dibenzocycloheptenes
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Led Devices (AREA)
- Surgical Instruments (AREA)
- Eye Examination Apparatus (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP26723295 | 1995-10-16 | ||
JP32429895 | 1995-12-13 | ||
PCT/JP1996/002997 WO1997014672A1 (fr) | 1995-10-16 | 1996-10-16 | Composes tricycliques |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69612835D1 DE69612835D1 (de) | 2001-06-21 |
DE69612835T2 true DE69612835T2 (de) | 2001-10-04 |
Family
ID=26547771
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69612835T Expired - Fee Related DE69612835T2 (de) | 1995-10-16 | 1996-10-16 | Tricyclische verbindungen |
Country Status (12)
Country | Link |
---|---|
US (1) | US5726325A (de) |
EP (1) | EP0798288B1 (de) |
JP (1) | JP3847786B2 (de) |
CN (1) | CN1168133A (de) |
AT (1) | ATE201195T1 (de) |
AU (1) | AU700386B2 (de) |
DE (1) | DE69612835T2 (de) |
ES (1) | ES2159047T3 (de) |
HU (1) | HUP9801356A3 (de) |
NO (1) | NO972726L (de) |
NZ (1) | NZ320580A (de) |
WO (1) | WO1997014672A1 (de) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5840749A (en) * | 1989-08-25 | 1998-11-24 | Hoechst Marion Roussel, Inc. | N-hydroxy-dibenz b,e!oxepinalkylamines, N-hydroxy-dibenz b,e!oxepinalkanoic acid amides and related heterocyclic analogues |
AU6471896A (en) * | 1995-07-24 | 1997-02-18 | Takeda Chemical Industries Ltd. | Production of optically active benzothiepin salts |
ATE339409T1 (de) | 1997-04-15 | 2006-10-15 | Kyowa Hakko Kogyo Kk | Trizyklische verbindungen |
DE60036758T2 (de) | 1999-08-04 | 2008-07-24 | Sumitomo Chemical Co., Ltd. | Verfahren zur Herstellung von optisch aktiver 3,3,3-Trifluor-2-hydroxy-2-methylpropionsäure und deren Salze |
KR20040007477A (ko) | 2001-03-30 | 2004-01-24 | 교와 핫꼬 고교 가부시끼가이샤 | 전립선 비대증과 연관된 방광 과민증 치료제 |
MXPA03008725A (es) * | 2001-03-30 | 2004-04-05 | Kyowa Hakko Kogyo Kk | Medicamentos para hiperactividad vesicular. |
EP1384481A1 (de) * | 2001-03-30 | 2004-01-28 | Kyowa Hakko Kogyo Co., Ltd. | Mittel zur behandlung von vesikaler hyperästhesie |
WO2003041704A1 (fr) * | 2001-11-13 | 2003-05-22 | Kyowa Hakko Kogyo Co., Ltd. | Agent preventif ou remede destine au prurit |
TW200400816A (en) * | 2002-06-26 | 2004-01-16 | Lilly Co Eli | Tricyclic steroid hormone nuclear receptor modulators |
US20060205756A1 (en) * | 2003-03-31 | 2006-09-14 | Kyowa Hakko Kogyo Co., Ltd. | Antitussives |
AR044870A1 (es) * | 2003-06-27 | 2005-10-05 | Kyowa Hakko Kogyo Kk | Compuesto azufrado triciclico y su uso como agente terapeutico para la vejiga hiperactiva |
WO2005007154A1 (ja) * | 2003-07-16 | 2005-01-27 | Kyowa Hakko Kogyo Co., Ltd. | 疼痛の予防及び/または治療剤 |
JPWO2005011674A1 (ja) * | 2003-08-05 | 2006-09-14 | 協和醗酵工業株式会社 | 気管支喘息の予防及び/または治療剤 |
FR2872159B1 (fr) * | 2004-06-28 | 2007-10-05 | Merck Sante Soc Par Actions Si | Nouveaux derives acides carboxyliques phenyliques et leur utilisation dans le traitement du diabete |
TW200606133A (en) * | 2004-06-30 | 2006-02-16 | Sankyo Co | Substituted benzene compounds |
DE102005022020A1 (de) * | 2005-05-12 | 2006-11-23 | Merckle Gmbh | Dibenzocycloheptanverbindungen und pharmazeutische Mittel, welche diese Verbindungen enthalten |
JP4119478B1 (ja) * | 2005-06-23 | 2008-07-16 | メルク エンド カムパニー インコーポレーテッド | チロシンキナーゼインヒビター |
AU2006306517A1 (en) * | 2005-10-21 | 2007-05-03 | Merck Sharp & Dohme Corp. | Tyrosine kinase inhibitors |
WO2007050383A2 (en) * | 2005-10-21 | 2007-05-03 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
WO2007050380A2 (en) * | 2005-10-21 | 2007-05-03 | Merck & Co., Inc. | Tyrosine kinase inhibitors |
TW200813021A (en) * | 2006-07-10 | 2008-03-16 | Merck & Co Inc | Tyrosine kinase inhibitors |
TW200827367A (en) | 2006-10-26 | 2008-07-01 | Kyowa Hakko Kogyo Kk | A therapeutic agent for irritable bowel syndrome |
WO2019084452A1 (en) * | 2017-10-27 | 2019-05-02 | Transfusion Health, Llc | COMPOSITIONS AND METHODS FOR PRODUCING EXPANDED HEMATOPOIETIC STEM CELLS USING FLUORENE DERIVATIVES |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3458578A (en) * | 1965-03-22 | 1969-07-29 | Sandoz Ag | Aminodibenzocycloalkenones |
US4477465A (en) * | 1983-03-10 | 1984-10-16 | Hoechst-Roussel Pharmaceuticals Inc. | Substituted 4,10-dihydro-10-oxothieno benzoxepins |
JPS6310784A (ja) * | 1986-03-03 | 1988-01-18 | Kyowa Hakko Kogyo Co Ltd | 抗アレルギー剤 |
GB9214120D0 (en) * | 1991-07-25 | 1992-08-12 | Ici Plc | Therapeutic amides |
-
1996
- 1996-10-16 CN CN96191517A patent/CN1168133A/zh active Pending
- 1996-10-16 AT AT96935342T patent/ATE201195T1/de active
- 1996-10-16 WO PCT/JP1996/002997 patent/WO1997014672A1/ja not_active Application Discontinuation
- 1996-10-16 US US08/849,399 patent/US5726325A/en not_active Expired - Fee Related
- 1996-10-16 HU HU9801356A patent/HUP9801356A3/hu unknown
- 1996-10-16 NZ NZ320580A patent/NZ320580A/xx unknown
- 1996-10-16 DE DE69612835T patent/DE69612835T2/de not_active Expired - Fee Related
- 1996-10-16 EP EP96935342A patent/EP0798288B1/de not_active Expired - Lifetime
- 1996-10-16 ES ES96935342T patent/ES2159047T3/es not_active Expired - Lifetime
- 1996-10-16 AU AU73326/96A patent/AU700386B2/en not_active Ceased
- 1996-10-16 JP JP51568797A patent/JP3847786B2/ja not_active Expired - Fee Related
-
1997
- 1997-06-13 NO NO972726A patent/NO972726L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
AU7332696A (en) | 1997-05-07 |
EP0798288B1 (de) | 2001-05-16 |
DE69612835D1 (de) | 2001-06-21 |
NO972726L (no) | 1997-08-05 |
HUP9801356A2 (hu) | 1998-10-28 |
CN1168133A (zh) | 1997-12-17 |
NO972726D0 (no) | 1997-06-13 |
AU700386B2 (en) | 1999-01-07 |
EP0798288A4 (de) | 1999-06-16 |
MX9704411A (es) | 1998-07-31 |
JP3847786B2 (ja) | 2006-11-22 |
NZ320580A (en) | 1998-12-23 |
WO1997014672A1 (fr) | 1997-04-24 |
EP0798288A1 (de) | 1997-10-01 |
HUP9801356A3 (en) | 2000-07-28 |
ES2159047T3 (es) | 2001-09-16 |
US5726325A (en) | 1998-03-10 |
ATE201195T1 (de) | 2001-06-15 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8339 | Ceased/non-payment of the annual fee |