DE69506426D1 - Vorrichtung zur iontophorestischen verabreichung versehen mit verbesserter sicherheit und vermeidung von missbräuchlichem potential - Google Patents
Vorrichtung zur iontophorestischen verabreichung versehen mit verbesserter sicherheit und vermeidung von missbräuchlichem potentialInfo
- Publication number
- DE69506426D1 DE69506426D1 DE69506426T DE69506426T DE69506426D1 DE 69506426 D1 DE69506426 D1 DE 69506426D1 DE 69506426 T DE69506426 T DE 69506426T DE 69506426 T DE69506426 T DE 69506426T DE 69506426 D1 DE69506426 D1 DE 69506426D1
- Authority
- DE
- Germany
- Prior art keywords
- disabling
- permanent
- current
- electrodes
- permanently
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0432—Anode and cathode
- A61N1/0436—Material of the electrode
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/20—Applying electric currents by contact electrodes continuous direct currents
- A61N1/30—Apparatus for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body, or cataphoresis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/18—Applying electric currents by contact electrodes
- A61N1/32—Applying electric currents by contact electrodes alternating or intermittent currents
- A61N1/325—Applying electric currents by contact electrodes alternating or intermittent currents for iontophoresis, i.e. transfer of media in ionic state by an electromotoric force into the body
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0412—Specially adapted for transcutaneous electroporation, e.g. including drug reservoirs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61N—ELECTROTHERAPY; MAGNETOTHERAPY; RADIATION THERAPY; ULTRASOUND THERAPY
- A61N1/00—Electrotherapy; Circuits therefor
- A61N1/02—Details
- A61N1/04—Electrodes
- A61N1/0404—Electrodes for external use
- A61N1/0408—Use-related aspects
- A61N1/0428—Specially adapted for iontophoresis, e.g. AC, DC or including drug reservoirs
- A61N1/0448—Drug reservoir
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Electrotherapy Devices (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Electrical Discharge Machining, Electrochemical Machining, And Combined Machining (AREA)
- Spinning Or Twisting Of Yarns (AREA)
- Elimination Of Static Electricity (AREA)
- Casings For Electric Apparatus (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US08/312,336 US7027859B1 (en) | 1994-09-26 | 1994-09-26 | Electrotransport delivery device having improved safety and reduced abuse potential |
PCT/US1995/012003 WO1996009850A2 (en) | 1994-09-26 | 1995-09-21 | Electrotransport delivery device having improved safety and reduced abuse potential |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69506426D1 true DE69506426D1 (de) | 1999-01-14 |
DE69506426T2 DE69506426T2 (de) | 1999-05-27 |
Family
ID=23210983
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69506426T Expired - Lifetime DE69506426T2 (de) | 1994-09-26 | 1995-09-21 | Vorrichtung zur iontophorestischen verabreichung versehen mit verbesserter sicherheit und vermeidung von missbräuchlichem potential |
Country Status (11)
Country | Link |
---|---|
US (3) | US7027859B1 (de) |
EP (1) | EP0781152B1 (de) |
JP (2) | JP4165659B2 (de) |
KR (1) | KR100372205B1 (de) |
AT (1) | ATE173942T1 (de) |
AU (1) | AU3594095A (de) |
CA (1) | CA2195657C (de) |
DE (1) | DE69506426T2 (de) |
DK (1) | DK0781152T3 (de) |
ES (1) | ES2125660T3 (de) |
WO (1) | WO1996009850A2 (de) |
Families Citing this family (66)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE69509782T2 (de) * | 1994-09-30 | 1999-11-11 | Becton Dickinson And Co., Franklin Lakes | Vorrichtung zur iontophoretischen verabreichung von medikamenten mit verbesserter steuereinrichtung und kissenelektrode |
US6881208B1 (en) * | 1995-06-05 | 2005-04-19 | Joseph B. Phipps | Method and device for transdermal electrotransport delivery of fentanyl and sufentanil |
US6029083A (en) * | 1997-04-04 | 2000-02-22 | Becton, Dickinson And Company | Circuit and method for automatically turning off an iontophoresis system |
US6208891B1 (en) * | 1997-04-04 | 2001-03-27 | Drug Delivery Technologies, Inc. | Disabling circuit for an iontophoretic system |
IL123290A (en) * | 1998-02-13 | 2001-12-23 | Hadasit Med Res Service | Iontophoretic device |
US6385488B1 (en) * | 1999-05-20 | 2002-05-07 | Vyteris, Inc. | Circuits for increasing the reliability of an iontophoretic system |
AU2000275456A1 (en) * | 2000-10-05 | 2002-04-15 | Spes Patents Limited | Apparatus for applying electronic treatment |
DE10141650C1 (de) | 2001-08-24 | 2002-11-28 | Lohmann Therapie Syst Lts | Transdermales Therapeutisches System mit Fentanyl bzw. verwandten Substanzen |
US7142909B2 (en) * | 2002-04-11 | 2006-11-28 | Second Sight Medical Products, Inc. | Biocompatible bonding method and electronics package suitable for implantation |
US7031769B2 (en) * | 2003-02-21 | 2006-04-18 | Birch Point Medical, Inc. | Dosage control electrode for iontophoresis device |
PE20051093A1 (es) * | 2004-01-30 | 2006-01-16 | Schering Corp | Polimorfos cristalinos de un ligando receptor de cxc quimiocina |
EP1960035A4 (de) * | 2005-11-30 | 2010-01-06 | Xavant Technology Pty Ltd | Medizinische vorrichtung |
US20080009782A1 (en) * | 2006-06-28 | 2008-01-10 | Alza Corporation | Methods and Devices for Transdermal Electrotransport Delivery of Lofentanil and Carfentanil |
US9119582B2 (en) | 2006-06-30 | 2015-09-01 | Abbott Diabetes Care, Inc. | Integrated analyte sensor and infusion device and methods therefor |
EP2043733A1 (de) * | 2007-06-26 | 2009-04-08 | Alza Corporation | Verfahren und vorrichtungen zur transdermalen elektrotransport-verabreichung von lofentanil und carfentanil |
US9345836B2 (en) | 2007-10-02 | 2016-05-24 | Medimop Medical Projects Ltd. | Disengagement resistant telescoping assembly and unidirectional method of assembly for such |
US9656019B2 (en) | 2007-10-02 | 2017-05-23 | Medimop Medical Projects Ltd. | Apparatuses for securing components of a drug delivery system during transport and methods of using same |
US7967795B1 (en) | 2010-01-19 | 2011-06-28 | Lamodel Ltd. | Cartridge interface assembly with driving plunger |
US10420880B2 (en) | 2007-10-02 | 2019-09-24 | West Pharma. Services IL, Ltd. | Key for securing components of a drug delivery system during assembly and/or transport and methods of using same |
US20090093793A1 (en) | 2007-10-02 | 2009-04-09 | Yossi Gross | External drug pump |
US9393369B2 (en) | 2008-09-15 | 2016-07-19 | Medimop Medical Projects Ltd. | Stabilized pen injector |
US8157769B2 (en) | 2009-09-15 | 2012-04-17 | Medimop Medical Projects Ltd. | Cartridge insertion assembly for drug delivery system |
US10071198B2 (en) | 2012-11-02 | 2018-09-11 | West Pharma. Servicees IL, Ltd. | Adhesive structure for medical device |
US10071196B2 (en) | 2012-05-15 | 2018-09-11 | West Pharma. Services IL, Ltd. | Method for selectively powering a battery-operated drug-delivery device and device therefor |
US8348898B2 (en) | 2010-01-19 | 2013-01-08 | Medimop Medical Projects Ltd. | Automatic needle for drug pump |
WO2011141907A1 (en) | 2010-05-10 | 2011-11-17 | Medimop Medical Projects Ltd. | Low volume accurate injector |
US9881521B2 (en) * | 2011-01-17 | 2018-01-30 | Prestan Products Llc | Manikin sensing pads and liners in an AED training system |
DE102011011910A1 (de) * | 2011-02-21 | 2012-08-23 | Giesecke & Devrient Gmbh | Inbetriebnahme eines portablen Datenträgers |
USD702834S1 (en) | 2011-03-22 | 2014-04-15 | Medimop Medical Projects Ltd. | Cartridge for use in injection device |
US8428709B1 (en) | 2012-06-11 | 2013-04-23 | Incline Therapeutics, Inc. | Current control for electrotransport drug delivery |
US8301238B2 (en) | 2011-03-31 | 2012-10-30 | Incline Therapeutics, Inc. | Two-part electrotransport device |
US8781571B2 (en) | 2011-03-31 | 2014-07-15 | Incline Therapeutics, Inc. | Switch validation circuit and method |
US9731121B2 (en) | 2011-03-31 | 2017-08-15 | Incline Therapeutics, Inc. | Switch validation circuit and method |
US8428708B1 (en) | 2012-05-21 | 2013-04-23 | Incline Therapeutics, Inc. | Self-test for analgesic product |
EP2809375B1 (de) | 2012-01-31 | 2021-08-11 | Medimop Medical Projects Ltd. | Zeitabhängige wirkstofffreisetzungsvorrichtung |
US10668213B2 (en) | 2012-03-26 | 2020-06-02 | West Pharma. Services IL, Ltd. | Motion activated mechanisms for a drug delivery device |
US9072827B2 (en) | 2012-03-26 | 2015-07-07 | Medimop Medical Projects Ltd. | Fail safe point protector for needle safety flap |
US9463280B2 (en) | 2012-03-26 | 2016-10-11 | Medimop Medical Projects Ltd. | Motion activated septum puncturing drug delivery device |
US9421323B2 (en) | 2013-01-03 | 2016-08-23 | Medimop Medical Projects Ltd. | Door and doorstop for portable one use drug delivery apparatus |
US9011164B2 (en) | 2013-04-30 | 2015-04-21 | Medimop Medical Projects Ltd. | Clip contact for easy installation of printed circuit board PCB |
US9889256B2 (en) | 2013-05-03 | 2018-02-13 | Medimop Medical Projects Ltd. | Sensing a status of an infuser based on sensing motor control and power input |
FR3015300B1 (fr) | 2013-12-20 | 2018-03-02 | L'oreal | Dispositif d'iontophorese a reservoir |
FR3015299B1 (fr) * | 2013-12-20 | 2017-10-06 | Oreal | Dispositif d'iontophorese a gestion independante de courant |
WO2016065190A1 (en) | 2014-10-23 | 2016-04-28 | Abbott Diabetes Care Inc. | Electrodes having at least one sensing structure and methods for making and using the same |
US9795534B2 (en) | 2015-03-04 | 2017-10-24 | Medimop Medical Projects Ltd. | Compliant coupling assembly for cartridge coupling of a drug delivery device |
US10251813B2 (en) | 2015-03-04 | 2019-04-09 | West Pharma. Services IL, Ltd. | Flexibly mounted cartridge alignment collar for drug delivery device |
US9744297B2 (en) | 2015-04-10 | 2017-08-29 | Medimop Medical Projects Ltd. | Needle cannula position as an input to operational control of an injection device |
US10293120B2 (en) | 2015-04-10 | 2019-05-21 | West Pharma. Services IL, Ltd. | Redundant injection device status indication |
AU2016202751B2 (en) * | 2015-04-30 | 2019-11-07 | Richard Malter | Iontophoresis device and method of treatment |
US10149943B2 (en) | 2015-05-29 | 2018-12-11 | West Pharma. Services IL, Ltd. | Linear rotation stabilizer for a telescoping syringe stopper driverdriving assembly |
EP3302652B1 (de) | 2015-06-04 | 2023-09-06 | Medimop Medical Projects Ltd. | Kartuscheneinführung für arzneimittelabgavevorrichtung |
KR101628299B1 (ko) * | 2015-09-09 | 2016-06-08 | (주)와이브레인 | 전극 패드 |
US10576207B2 (en) | 2015-10-09 | 2020-03-03 | West Pharma. Services IL, Ltd. | Angled syringe patch injector |
US9987432B2 (en) | 2015-09-22 | 2018-06-05 | West Pharma. Services IL, Ltd. | Rotation resistant friction adapter for plunger driver of drug delivery device |
JP7044708B2 (ja) | 2015-10-09 | 2022-03-30 | ウェスト ファーマ サービシーズ イスラエル リミテッド | カスタマイズシリンジの充填方法 |
CN108366630B (zh) * | 2016-01-08 | 2022-11-01 | 菲利普莫里斯生产公司 | 用于包括禁用构件的气溶胶生成***的部件 |
JP6885960B2 (ja) | 2016-01-21 | 2021-06-16 | ウェスト ファーマ サービシーズ イスラエル リミテッド | 視覚的インジケータを有する薬剤デリバリデバイス |
EP3405229A1 (de) | 2016-01-21 | 2018-11-28 | West Pharma. Services Il, Ltd. | Nadeleinführ- und retraktionsmechanismus |
JP6513297B2 (ja) | 2016-01-21 | 2019-05-22 | ウェスト ファーマ サービシーズ イスラエル リミテッド | 自動注射器、受け入れフレーム及び自動注射器におけるカートリッジの接続方法 |
WO2017161076A1 (en) | 2016-03-16 | 2017-09-21 | Medimop Medical Projects Ltd. | Staged telescopic screw assembly having different visual indicators |
EP3463526A1 (de) | 2016-06-02 | 2019-04-10 | West Pharma. Services Il, Ltd. | Nadelrückzug mit drei positionen |
CN113577438B (zh) | 2016-08-01 | 2023-05-23 | 西医药服务以色列有限公司 | 部分门关闭防止弹簧 |
US11338090B2 (en) | 2016-08-01 | 2022-05-24 | West Pharma. Services IL, Ltd. | Anti-rotation cartridge pin |
US11819666B2 (en) | 2017-05-30 | 2023-11-21 | West Pharma. Services IL, Ltd. | Modular drive train for wearable injector |
US11857767B2 (en) | 2017-12-22 | 2024-01-02 | West Pharma. Services IL, Ltd. | Injector usable with different dimension cartridges |
US11139256B2 (en) * | 2019-08-21 | 2021-10-05 | Micron Technology, Inc. | Tamper-resistant integrated circuits, and related methods |
Family Cites Families (37)
Publication number | Priority date | Publication date | Assignee | Title |
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US3493657A (en) | 1961-03-14 | 1970-02-03 | Mozes Juda Lewenstein | Therapeutic compositions of n-allyl-14-hydroxy - dihydronormorphinane and morphine |
US3773955A (en) | 1970-08-03 | 1973-11-20 | Bristol Myers Co | Analgetic compositions |
US4141359A (en) | 1976-08-16 | 1979-02-27 | University Of Utah | Epidermal iontophoresis device |
JPS54109279A (en) * | 1978-02-15 | 1979-08-27 | Masao Oku | Electric medicine injector |
US4457933A (en) | 1980-01-24 | 1984-07-03 | Bristol-Myers Company | Prevention of analgesic abuse |
JPS5810066A (ja) | 1981-07-10 | 1983-01-20 | 株式会社アドバンス | イオントフオレ−ゼ用プラスタ−構造体 |
JPS58183044A (ja) | 1982-04-21 | 1983-10-26 | Q P Corp | 高速割卵機における殻付卵の受渡し方法およびその装置 |
US4731926A (en) | 1985-02-19 | 1988-03-22 | Drug Delivery Systems Inc. | Method of manufacturing disposable and/or replenishable transdermal drug applicators |
US5167617A (en) | 1983-08-18 | 1992-12-01 | Drug Delivery Systems Inc. | Disposable electralytic transdermal drug applicator |
US5135479A (en) | 1983-08-18 | 1992-08-04 | Drug Delivery Systems, Inc. | Programmable control and mounting system for transdermal drug applicator |
US5224928A (en) | 1983-08-18 | 1993-07-06 | Drug Delivery Systems Inc. | Mounting system for transdermal drug applicator |
US4588580B2 (en) | 1984-07-23 | 1999-02-16 | Alaz Corp | Transdermal administration of fentanyl and device therefor |
US5135477A (en) | 1984-10-29 | 1992-08-04 | Medtronic, Inc. | Iontophoretic drug delivery |
MX169673B (es) * | 1985-06-10 | 1993-07-19 | Drug Delivery Systems Inc | Control programable y sistema de montaje para un aplicador de medicamento trans-dermico |
JPH0657259B2 (ja) | 1986-04-21 | 1994-08-03 | 松下電工株式会社 | 低周波美容器 |
US4822334A (en) * | 1986-12-04 | 1989-04-18 | Robert Tapper | Electrical dosimetry control system |
US4942883A (en) | 1987-09-29 | 1990-07-24 | Newman Martin H | Drug delivery device |
US5169382A (en) | 1988-10-03 | 1992-12-08 | Alza Corporation | Membrane for electrotransport transdermal drug delivery |
US5006108A (en) | 1988-11-16 | 1991-04-09 | Noven Pharmaceuticals, Inc. | Apparatus for iontophoretic drug delivery |
JP2822215B2 (ja) * | 1989-07-17 | 1998-11-11 | 林原 健 | 頭皮を通電刺激するための装置 |
JPH03173317A (ja) | 1989-11-30 | 1991-07-26 | Nippondenso Co Ltd | 太陽光利用電源装置 |
IT1244030B (it) | 1989-12-21 | 1994-06-28 | Elan Corp Plc | Dispostitivo in due parti per la somministrazione controllata di un ingrediente |
US5047007A (en) | 1989-12-22 | 1991-09-10 | Medtronic, Inc. | Method and apparatus for pulsed iontophoretic drug delivery |
US5213568A (en) * | 1990-03-30 | 1993-05-25 | Medtronic Inc. | Activity controlled electrotransport drug delivery device |
US5207752A (en) | 1990-03-30 | 1993-05-04 | Alza Corporation | Iontophoretic drug delivery system with two-stage delivery profile |
JP2801083B2 (ja) * | 1990-04-30 | 1998-09-21 | アルザ・コーポレーション | イオン導入による薬物投与デバイスと方法 |
US5147297A (en) | 1990-05-07 | 1992-09-15 | Alza Corporation | Iontophoretic delivery device |
US5037381A (en) * | 1990-07-27 | 1991-08-06 | Bock C Randolph | Electrically assisted transdermal transport device and method for renewing the device |
US5160316A (en) * | 1990-09-10 | 1992-11-03 | Henley Julian L | Iontophoretic drug delivery apparatus |
US5224927A (en) | 1990-11-01 | 1993-07-06 | Robert Tapper | Iontophoretic treatment system |
US5254081A (en) | 1991-02-01 | 1993-10-19 | Empi, Inc. | Multiple site drug iontophoresis electronic device and method |
US5203768A (en) | 1991-07-24 | 1993-04-20 | Alza Corporation | Transdermal delivery device |
US5246417A (en) * | 1991-12-11 | 1993-09-21 | Alza Corporation | Indicator for iontophoresis system |
US5246418A (en) | 1991-12-17 | 1993-09-21 | Becton Dickinson And Company | Iontophresis system having features for reducing skin irritation |
FR2687321B1 (fr) * | 1992-02-14 | 1999-04-16 | Elf Aquitaine | Dispositif d'ionophorese pour l'administration transcutanee d'une quantite totale donnee d'un principe actif a un sujet. |
JPH0623060A (ja) * | 1992-07-07 | 1994-02-01 | Citizen Watch Co Ltd | 電子薬物投与器 |
US5306235A (en) | 1992-09-30 | 1994-04-26 | Becton Dickinson And Company | Failsafe iontophoresis drug delivery system |
-
1994
- 1994-09-26 US US08/312,336 patent/US7027859B1/en not_active Expired - Lifetime
-
1995
- 1995-09-21 ES ES95933180T patent/ES2125660T3/es not_active Expired - Lifetime
- 1995-09-21 AU AU35940/95A patent/AU3594095A/en not_active Abandoned
- 1995-09-21 JP JP51187996A patent/JP4165659B2/ja not_active Expired - Fee Related
- 1995-09-21 DE DE69506426T patent/DE69506426T2/de not_active Expired - Lifetime
- 1995-09-21 AT AT95933180T patent/ATE173942T1/de not_active IP Right Cessation
- 1995-09-21 KR KR1019970701946A patent/KR100372205B1/ko not_active IP Right Cessation
- 1995-09-21 DK DK95933180T patent/DK0781152T3/da active
- 1995-09-21 WO PCT/US1995/012003 patent/WO1996009850A2/en active IP Right Grant
- 1995-09-21 CA CA002195657A patent/CA2195657C/en not_active Expired - Fee Related
- 1995-09-21 EP EP95933180A patent/EP0781152B1/de not_active Expired - Lifetime
-
2006
- 2006-01-18 US US11/334,001 patent/US7660627B2/en not_active Expired - Fee Related
-
2008
- 2008-05-07 JP JP2008121143A patent/JP4322304B2/ja not_active Expired - Fee Related
-
2009
- 2009-11-30 US US12/627,230 patent/US20100076368A1/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
US20060116662A1 (en) | 2006-06-01 |
KR970706037A (ko) | 1997-11-03 |
EP0781152B1 (de) | 1998-12-02 |
JP4322304B2 (ja) | 2009-08-26 |
EP0781152A2 (de) | 1997-07-02 |
WO1996009850A2 (en) | 1996-04-04 |
JP2008220985A (ja) | 2008-09-25 |
WO1996009850A3 (en) | 1996-05-30 |
DE69506426T2 (de) | 1999-05-27 |
US7027859B1 (en) | 2006-04-11 |
AU3594095A (en) | 1996-04-19 |
ATE173942T1 (de) | 1998-12-15 |
US7660627B2 (en) | 2010-02-09 |
ES2125660T3 (es) | 1999-03-01 |
US20100076368A1 (en) | 2010-03-25 |
CA2195657C (en) | 2009-12-22 |
DK0781152T3 (da) | 1999-08-16 |
KR100372205B1 (ko) | 2003-04-10 |
CA2195657A1 (en) | 1996-04-04 |
JPH10506553A (ja) | 1998-06-30 |
JP4165659B2 (ja) | 2008-10-15 |
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