DE69425804T2 - Phosphonsäurediesterderivate - Google Patents
PhosphonsäurediesterderivateInfo
- Publication number
- DE69425804T2 DE69425804T2 DE69425804T DE69425804T DE69425804T2 DE 69425804 T2 DE69425804 T2 DE 69425804T2 DE 69425804 T DE69425804 T DE 69425804T DE 69425804 T DE69425804 T DE 69425804T DE 69425804 T2 DE69425804 T2 DE 69425804T2
- Authority
- DE
- Germany
- Prior art keywords
- lower alkyl
- represent
- phenyl
- independently hydrogen
- phosphonic acid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having three nitrogen atoms as the only ring hetero atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6558—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system
- C07F9/65583—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing at least two different or differently substituted hetero rings neither condensed among themselves nor condensed with a common carbocyclic ring or ring system each of the hetero rings containing nitrogen as ring hetero atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic System
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/645—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having two nitrogen atoms as the only ring hetero atoms
- C07F9/6509—Six-membered rings
- C07F9/6512—Six-membered rings having the nitrogen atoms in positions 1 and 3
- C07F9/65128—Six-membered rings having the nitrogen atoms in positions 1 and 3 condensed with carbocyclic rings or carbocyclic ring systems
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP14652893 | 1993-06-17 | ||
| PCT/JP1994/000883 WO1995000524A1 (fr) | 1993-06-17 | 1994-05-31 | Derive de diester phosphonique |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69425804D1 DE69425804D1 (en) | 2000-10-12 |
| DE69425804T2 true DE69425804T2 (de) | 2001-02-08 |
Family
ID=15409687
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69425804T Expired - Fee Related DE69425804T2 (de) | 1993-06-17 | 1994-05-31 | Phosphonsäurediesterderivate |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US5624918A (de) |
| EP (1) | EP0655456B1 (de) |
| KR (1) | KR100297623B1 (de) |
| CN (1) | CN1048018C (de) |
| AT (1) | ATE196145T1 (de) |
| AU (1) | AU664337B2 (de) |
| CA (1) | CA2142597C (de) |
| DE (1) | DE69425804T2 (de) |
| TW (1) | TW278078B (de) |
| WO (1) | WO1995000524A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2184891C (en) * | 1994-03-08 | 2000-09-26 | Yasuhisa Kuroki | Phosphonic diester derivative |
| JP3533542B2 (ja) * | 1994-03-08 | 2004-05-31 | 株式会社大塚製薬工場 | ホスホン酸ジエステル誘導体 |
| US6292113B1 (en) | 1997-03-25 | 2001-09-18 | Primax Electronics Ltd. | Finger operated module for generating encoding signals |
| US6157369A (en) | 1997-10-14 | 2000-12-05 | Logitech, Inc. | Optical-mechanical roller with ratchet |
| DE19756388A1 (de) * | 1997-12-18 | 1999-06-24 | Hoechst Marion Roussel De Gmbh | Substituierte 2-Aryl-4-amino-chinazoline |
| US6184226B1 (en) * | 1998-08-28 | 2001-02-06 | Scios Inc. | Quinazoline derivatives as inhibitors of P-38 α |
| US6326949B1 (en) | 1999-03-11 | 2001-12-04 | Logitech Europe S.A. | Wheel support guide for vertical wheel support movement |
| WO2001083456A1 (fr) * | 2000-04-27 | 2001-11-08 | Yamanouchi Pharmaceutical Co., Ltd. | Derives d'heteroaryle condenses |
| US6608053B2 (en) | 2000-04-27 | 2003-08-19 | Yamanouchi Pharmaceutical Co., Ltd. | Fused heteroaryl derivatives |
| WO2003000188A2 (en) * | 2001-06-21 | 2003-01-03 | Ariad Pharmaceuticals, Inc. | Novel quinazolines and uses thereof |
| US20040192583A1 (en) * | 2002-12-19 | 2004-09-30 | Satyanarayana Medicherla | Treatment of obesity and associated conditions with TGF-beta inhibitors |
| US7713983B2 (en) | 2003-03-03 | 2010-05-11 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of ion channels |
| CL2004000409A1 (es) | 2003-03-03 | 2005-01-07 | Vertex Pharma | Compuestos derivados de 2-(cilo sustituido)-1-(amino u oxi sustituido)-quinazolina, inhibidores de canales ionicos de sodio y calcio dependientes de voltaje; composicion farmaceutica; y uso del compuesto en el tratamiento de dolor agudo, cronico, neu |
| ZA200507979B (en) * | 2003-03-03 | 2007-03-28 | Vertex Pharma Inc | Quinazolines useful as modulators of ion channels |
| US7928107B2 (en) | 2004-09-02 | 2011-04-19 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of ion channels |
| US8283354B2 (en) | 2004-09-02 | 2012-10-09 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of ion channels |
| PL2473487T3 (pl) * | 2009-09-03 | 2017-07-31 | Bristol-Myers Squibb Company | Chinazoliny jako inhibitory kanałów jonowych potasowych |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS543589A (en) * | 1977-06-09 | 1979-01-11 | Omron Tateisi Electronics Co | Coating defect detecting apparatus of sheet form objects |
| AU523040B2 (en) * | 1978-05-15 | 1982-07-08 | Kanebo Limited | Calcium -antagonistic composition |
| US4434162A (en) * | 1981-02-17 | 1984-02-28 | Kanebo, Ltd. | Phosphonic acid ester, pharmaceutical compositions containing the same and method of using the same |
| JPH0651625B2 (ja) * | 1986-12-29 | 1994-07-06 | 株式会社大塚製薬工場 | 高脂質血症治療剤 |
| US4822780A (en) * | 1987-07-08 | 1989-04-18 | Otsuka Pharmaceutical Factory, Inc. | Carboxamide compounds |
| AU606808B2 (en) * | 1988-06-29 | 1991-02-14 | Otsuka Pharmaceutical Factory, Inc. | Arylcarboxamide substituted by alkylphosphonates, process for preparing the same and a pharmaceutical composition containing the same |
| CA2002864C (en) * | 1988-11-29 | 1999-11-16 | Eddy J. E. Freyne | (1h-azol-1-ylmethyl) substituted quinoline, quinazoline or quinoxaline derivatives |
| JP2584336B2 (ja) * | 1989-05-30 | 1997-02-26 | 株式会社大塚製薬工場 | カルボン酸アミド誘導体 |
| JP2549950B2 (ja) * | 1991-01-24 | 1996-10-30 | 株式会社大塚製薬工場 | イミダゾ［１，２−ａ］ピリジン誘導体、その製造方法及びその中間体としてのα−ハロケトン誘導体 |
| JP2696150B2 (ja) * | 1991-02-05 | 1998-01-14 | 株式会社大塚製薬工場 | キノリン誘導体 |
-
1994
- 1994-05-31 AT AT94917137T patent/ATE196145T1/de not_active IP Right Cessation
- 1994-05-31 KR KR1019950700619A patent/KR100297623B1/ko not_active IP Right Cessation
- 1994-05-31 US US08/387,907 patent/US5624918A/en not_active Expired - Lifetime
- 1994-05-31 WO PCT/JP1994/000883 patent/WO1995000524A1/ja active IP Right Grant
- 1994-05-31 CN CN94190513A patent/CN1048018C/zh not_active Expired - Fee Related
- 1994-05-31 DE DE69425804T patent/DE69425804T2/de not_active Expired - Fee Related
- 1994-05-31 AU AU68558/94A patent/AU664337B2/en not_active Ceased
- 1994-05-31 EP EP94917137A patent/EP0655456B1/de not_active Expired - Lifetime
- 1994-05-31 CA CA002142597A patent/CA2142597C/en not_active Expired - Fee Related
- 1994-06-16 TW TW083105440A patent/TW278078B/zh active
Also Published As
| Publication number | Publication date |
|---|---|
| ATE196145T1 (de) | 2000-09-15 |
| CA2142597C (en) | 2004-01-13 |
| EP0655456A4 (de) | 1996-03-27 |
| KR950702997A (ko) | 1995-08-23 |
| EP0655456B1 (de) | 2000-09-06 |
| CA2142597A1 (en) | 1995-01-05 |
| CN1112365A (zh) | 1995-11-22 |
| AU664337B2 (en) | 1995-11-09 |
| WO1995000524A1 (fr) | 1995-01-05 |
| EP0655456A1 (de) | 1995-05-31 |
| AU6855894A (en) | 1995-01-17 |
| CN1048018C (zh) | 2000-01-05 |
| TW278078B (de) | 1996-06-11 |
| KR100297623B1 (ko) | 2001-11-14 |
| US5624918A (en) | 1997-04-29 |
| DE69425804D1 (en) | 2000-10-12 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE69425804T2 (de) | Phosphonsäurediesterderivate | |
| NO954564D0 (no) | N-acylsulfaminsyre-estere (eller-tioestere), N-acylsulfonamider og N-sulfonyl-karbaminsyre-estere (eller-tioestere) som hypercholesterolemiske midler | |
| IS6257A (is) | Frumuviðloðunartálmar | |
| DK0976748T3 (da) | Pyrrolidinderivater med phospholispase A2-hæmmende aktivitet | |
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| DE69415436D1 (de) | Phosphonsäure diester-derivate | |
| DK0916651T3 (da) | Phenylalkylcarboxylsyrederivater | |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |