DE69232252D1 - Herstellung und Verwendung von aktivierten Carbamaten - Google Patents

Herstellung und Verwendung von aktivierten Carbamaten

Info

Publication number
DE69232252D1
DE69232252D1 DE69232252T DE69232252T DE69232252D1 DE 69232252 D1 DE69232252 D1 DE 69232252D1 DE 69232252 T DE69232252 T DE 69232252T DE 69232252 T DE69232252 T DE 69232252T DE 69232252 D1 DE69232252 D1 DE 69232252D1
Authority
DE
Germany
Prior art keywords
production
activated carbamates
carbamates
activated
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69232252T
Other languages
English (en)
Other versions
DE69232252T2 (de
Inventor
Steven Cohen
Dennis Michaud
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Waters Investments Ltd
Original Assignee
Waters Investments Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Waters Investments Ltd filed Critical Waters Investments Ltd
Application granted granted Critical
Publication of DE69232252D1 publication Critical patent/DE69232252D1/de
Publication of DE69232252T2 publication Critical patent/DE69232252T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/531Production of immunochemical test materials
    • G01N33/532Production of labelled immunochemicals
    • G01N33/533Production of labelled immunochemicals with fluorescent label
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • G01N33/6803General methods of protein analysis not limited to specific proteins or families of proteins
    • G01N33/6818Sequencing of polypeptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Cell Biology (AREA)
  • Pathology (AREA)
  • General Physics & Mathematics (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Food Science & Technology (AREA)
  • Medicinal Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Bioinformatics & Computational Biology (AREA)
  • Biophysics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pyrrole Compounds (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
DE69232252T 1991-09-19 1992-09-18 Herstellung und Verwendung von aktivierten Carbamaten Expired - Lifetime DE69232252T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/762,579 US5296599A (en) 1991-09-19 1991-09-19 Activated carbamates compounds

Publications (2)

Publication Number Publication Date
DE69232252D1 true DE69232252D1 (de) 2002-01-17
DE69232252T2 DE69232252T2 (de) 2002-07-18

Family

ID=25065471

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69232252T Expired - Lifetime DE69232252T2 (de) 1991-09-19 1992-09-18 Herstellung und Verwendung von aktivierten Carbamaten

Country Status (4)

Country Link
US (1) US5296599A (de)
EP (1) EP0533200B1 (de)
JP (1) JP3128353B2 (de)
DE (1) DE69232252T2 (de)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5352803A (en) * 1992-03-30 1994-10-04 Abbott Laboratories 5(6)-methyl substituted fluorescein derivatives
WO1993020442A1 (en) * 1992-03-30 1993-10-14 Abbott Laboratories Reagents and methods for the detection and quantification of thyroxine in fluid samples
US6426190B1 (en) * 1995-04-20 2002-07-30 Carnegie Mellon University Difference detection methods using matched multiple dyes
US6127134A (en) * 1995-04-20 2000-10-03 Carnegie Mellon University Difference gel electrophoresis using matched multiple dyes
FR2788518B1 (fr) 1999-01-14 2001-03-02 Centre Nat Rech Scient Nouveaux carbamates actives stables, leur procede de preparation et leur utilisation pour la preparation d'urees
US6468761B2 (en) 2000-01-07 2002-10-22 Caliper Technologies, Corp. Microfluidic in-line labeling method for continuous-flow protease inhibition analysis
GB0113435D0 (en) * 2001-06-04 2001-07-25 Amersham Pharm Biotech Uk Ltd Acridone derivatives as labels for fluorescence detection of target materials
EP1475632B1 (de) * 2002-02-14 2013-05-22 Ajinomoto Co., Inc. Verfahren zur analyse einer aminofunktionellen verbindung und analytisches reagens
EP1750126B1 (de) * 2004-05-26 2015-09-16 Ajinomoto Co., Inc. Verfahren und vorrichtung zur analyse einer aminofunktionalen verbindung
FR2889700B1 (fr) * 2005-08-11 2012-11-23 Synthinnove Lab Marqueurs, leur procede de fabrication et leurs applications
JP5548363B2 (ja) * 2005-10-28 2014-07-16 アルマック サイエンシーズ (スコットランド) リミテッド 新規な蛍光染料およびその使用
US20080033167A1 (en) 2005-12-29 2008-02-07 Gilles Guichard Compositions and methods for synthesizing heterocyclic therapeutic compounds
CN101440062B (zh) * 2007-11-23 2011-09-28 齐齐哈尔大学 N-酰基-8-氨基喹啉衍生物的合成及其作为荧光分子探针的应用
WO2009070233A1 (en) * 2007-11-26 2009-06-04 Waters Technologies Corporation Internal standards and methods for use in quantitatively measuring analytes in a sample
EP2252584B1 (de) 2008-02-04 2016-12-07 Prozyme, Inc. Verbindungen und verfahren zur schnellen markierung von n-glykanen
GB201004372D0 (en) * 2010-03-16 2010-04-28 Almac Sciences Scotland Ltd Compounds for purification
US10436790B2 (en) 2011-09-28 2019-10-08 Waters Technologies Corporation Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals
US10416166B2 (en) 2011-09-28 2019-09-17 Waters Technologies Corporation Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals
US11352325B2 (en) 2011-09-28 2022-06-07 Waters Technologies Corporation Rapid fluorescence tagging of glycans and other biomolecules with enhanced MS signals
EP2990401A1 (de) 2014-08-13 2016-03-02 Waters Technologies Corporation Schnelle fluoreszenzmarkierung von glykanen und anderen biomolekülen mit verbesserten ms-signalen
JP7055634B2 (ja) 2014-10-30 2022-04-18 ウオーターズ・テクノロジーズ・コーポレイシヨン 標識化グリコシルアミンの迅速調製およびそれを生成するグリコシル化生体分子の分析方法
CN111796039B (zh) 2014-11-13 2023-03-17 沃特世科技公司 快速标记的n-聚糖的液相色谱校准方法
US9857339B2 (en) 2015-01-06 2018-01-02 Waters Technologies Corporation Automated sampling and reaction system for high pressure liquid chromatography and other types of detection
EP3786619B1 (de) 2015-05-29 2022-06-22 Agilent Technologies, Inc. Verbindungen zur markierung von aminhaltigen verbindungen und deren verwendung
CN109154604B (zh) 2016-04-24 2023-07-21 沃特世科技公司 用于对用两亲强碱性部分改性的聚糖进行分析的带电表面反相色谱材料方法
US11061023B2 (en) 2016-06-21 2021-07-13 Waters Technologies Corporation Fluorescence tagging of glycans and other biomolecules through reductive amination for enhanced MS signals
US11035832B2 (en) 2016-06-21 2021-06-15 Waters Technologies Corporation Methods of electrospray ionization of glycans modified with amphipathic, strongly basic moieties
CN109690297A (zh) 2016-07-01 2019-04-26 沃特世科技公司 使用分子量截留过滤和过滤器上去糖基化从复杂基质快速制备标记的葡基胺的方法
EP3519832B1 (de) 2016-10-03 2024-04-03 Waters Technologies Corporation Markierte glycanaminosäurekomplexe für die lc-ms-analyse und verfahren zur herstellung davon
EP3628652A1 (de) 2018-09-28 2020-04-01 Eberhard Karls Universität Tübingen Verfahren zur stereoisomerisierung von chiralen verbindungen
CN113045491A (zh) * 2019-12-26 2021-06-29 罗欣药业(上海)有限公司 一种仑伐替尼及中间体的制备方法
CN114755319A (zh) * 2022-03-08 2022-07-15 上海市第六人民医院 一种快速定量唾液中氨基酸及其衍生物的方法和试剂盒

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL93432A (en) * 1989-02-24 1994-02-27 Johnson Mathey Inc Hydrazines and hydrazides, their conjugates with macromolecules, and such conjugates labeled with metallic ions

Also Published As

Publication number Publication date
EP0533200B1 (de) 2001-12-05
EP0533200A1 (de) 1993-03-24
US5296599A (en) 1994-03-22
JPH05222033A (ja) 1993-08-31
JP3128353B2 (ja) 2001-01-29
DE69232252T2 (de) 2002-07-18

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