DE69029726D1 - Festphasendiagnose von medizinischen konditionen - Google Patents

Festphasendiagnose von medizinischen konditionen

Info

Publication number
DE69029726D1
DE69029726D1 DE69029726T DE69029726T DE69029726D1 DE 69029726 D1 DE69029726 D1 DE 69029726D1 DE 69029726 T DE69029726 T DE 69029726T DE 69029726 T DE69029726 T DE 69029726T DE 69029726 D1 DE69029726 D1 DE 69029726D1
Authority
DE
Germany
Prior art keywords
dna
label
solid support
primer pair
pair
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69029726T
Other languages
English (en)
Other versions
DE69029726T2 (de
Inventor
Mathias Uhlen
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
CEMU Bioteknik AB
Original Assignee
CEMU Bioteknik AB
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB898906642A external-priority patent/GB8906642D0/en
Priority claimed from GB898906641A external-priority patent/GB8906641D0/en
Application filed by CEMU Bioteknik AB filed Critical CEMU Bioteknik AB
Publication of DE69029726D1 publication Critical patent/DE69029726D1/de
Application granted granted Critical
Publication of DE69029726T2 publication Critical patent/DE69029726T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • F—MECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F16—ENGINEERING ELEMENTS AND UNITS; GENERAL MEASURES FOR PRODUCING AND MAINTAINING EFFECTIVE FUNCTIONING OF MACHINES OR INSTALLATIONS; THERMAL INSULATION IN GENERAL
    • F16C—SHAFTS; FLEXIBLE SHAFTS; ELEMENTS OR CRANKSHAFT MECHANISMS; ROTARY BODIES OTHER THAN GEARING ELEMENTS; BEARINGS
    • F16C33/00—Parts of bearings; Special methods for making bearings or parts thereof
    • F16C33/02—Parts of sliding-contact bearings
    • F16C33/04—Brasses; Bushes; Linings
    • F16C33/20—Sliding surface consisting mainly of plastics
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6844—Nucleic acid amplification reactions
    • C12Q1/6846—Common amplification features

Landscapes

  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Health & Medical Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Mechanical Engineering (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Ultra Sonic Daignosis Equipment (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Materials For Medical Uses (AREA)
  • Laminated Bodies (AREA)
  • Sliding-Contact Bearings (AREA)
DE69029726T 1989-03-22 1990-03-15 Festphasendiagnose von medizinischen konditionen Expired - Fee Related DE69029726T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB898906642A GB8906642D0 (en) 1989-03-22 1989-03-22 Amplification of target dna
GB898906641A GB8906641D0 (en) 1989-03-22 1989-03-22 Solid phase diagnosis of medical conditions
PCT/EP1990/000454 WO1990011369A1 (en) 1989-03-22 1990-03-15 Solid phase diagnosis of medical conditions

Publications (2)

Publication Number Publication Date
DE69029726D1 true DE69029726D1 (de) 1997-02-27
DE69029726T2 DE69029726T2 (de) 1997-09-04

Family

ID=26295125

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69029726T Expired - Fee Related DE69029726T2 (de) 1989-03-22 1990-03-15 Festphasendiagnose von medizinischen konditionen

Country Status (8)

Country Link
EP (1) EP0464067B1 (de)
JP (1) JP3152656B2 (de)
KR (1) KR920700360A (de)
AT (1) ATE147791T1 (de)
AU (1) AU646220B2 (de)
CA (1) CA2050681A1 (de)
DE (1) DE69029726T2 (de)
WO (1) WO1990011369A1 (de)

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WO1993004199A2 (en) * 1991-08-20 1993-03-04 Scientific Generics Limited Methods of detecting or quantitating nucleic acids and of producing labelled immobilised nucleic acids
AU660690B2 (en) * 1991-08-27 1995-07-06 Orchid Biosciences Europe Limited Method of characterisation
US5853989A (en) * 1991-08-27 1998-12-29 Zeneca Limited Method of characterisation of genomic DNA
EP0672173B1 (de) * 1991-11-01 2002-08-28 Diatech Pty. Ltd. Feststoff-phase erweiterungsverfahren
AU667846B2 (en) * 1991-11-01 1996-04-18 Diatech Pty Ltd Solid phase amplification process
IT1252295B (it) * 1991-11-15 1995-06-08 Schiapparelli Diagnostici Ismu Metodo per rivelare acidi nucleici e relativo kit diagnostico
GB9127415D0 (en) * 1991-12-24 1992-02-19 Swordfish Int Ltd Solid support bound detection and diagnostic system
GB9210176D0 (en) * 1992-05-12 1992-06-24 Cemu Bioteknik Ab Chemical method
DE4301693A1 (de) * 1993-01-22 1994-07-28 Cytech Biomedical Inc Verfahren zur Amplifikation und Verfahren zum Nachweis von Polynucleotidsequenzen an fester Phase
CA2158642A1 (en) * 1993-03-19 1994-09-29 Hubert Koster Dna sequencing by mass spectrometry via exonuclease degradation
EP0754240B1 (de) * 1994-02-07 2003-08-20 Beckman Coulter, Inc. Ligase/polymerase-vermittelte analyse genetischer elemente von einzelnukleotid-polymorphismen und ihre verwendung in der genetischen analyse
GB9408607D0 (en) * 1994-04-29 1994-06-22 Dynal As Assay
US6090592A (en) * 1994-08-03 2000-07-18 Mosaic Technologies, Inc. Method for performing amplification of nucleic acid on supports
US5641658A (en) * 1994-08-03 1997-06-24 Mosaic Technologies, Inc. Method for performing amplification of nucleic acid with two primers bound to a single solid support
GB9422814D0 (en) * 1994-11-11 1995-01-04 Medinnova Sf Chemical method
DE19526431A1 (de) * 1995-07-21 1997-01-23 Boehringer Mannheim Gmbh Verfahren und Reagenz zur spezifischen Bestimmung von mRNA
GB2308188A (en) * 1995-12-14 1997-06-18 Tepnel Medical Ltd Assaying immobilised nucleic acid by primer extension
US5962271A (en) * 1996-01-03 1999-10-05 Cloutech Laboratories, Inc. Methods and compositions for generating full-length cDNA having arbitrary nucleotide sequence at the 3'-end
GB9604267D0 (en) * 1996-02-29 1996-05-01 Royal Infirmary Of Edinburgh N Mutation assay
IT1284635B1 (it) * 1996-04-24 1998-05-21 Clonit Spa Metodo per la rivelazione di acidi nucleici amplificati e kit per il suo uso.
DE19616750A1 (de) * 1996-04-26 1997-11-06 Newlab Diagnostic Systems Gmbh Verfahren zum Nachweis von Mikroorganismen in Gemischen
GB9624165D0 (en) 1996-11-19 1997-01-08 Amdex A S Use of nucleic acids bound to carrier macromolecules
US7138511B1 (en) 1997-01-28 2006-11-21 The Regents Of The University Of California Nucleic acids, kits and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
US6475724B1 (en) 1997-01-28 2002-11-05 The Regents Of The University Of California Nucleic acids, kits, and methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
US6171788B1 (en) 1997-01-28 2001-01-09 The Regents Of The University Of California Methods for the diagnosis, prognosis and treatment of glaucoma and related disorders
AU6846698A (en) 1997-04-01 1998-10-22 Glaxo Group Limited Method of nucleic acid amplification
US6143496A (en) 1997-04-17 2000-11-07 Cytonix Corporation Method of sampling, amplifying and quantifying segment of nucleic acid, polymerase chain reaction assembly having nanoliter-sized sample chambers, and method of filling assembly
US5945284A (en) * 1997-05-27 1999-08-31 The Perkin-Elmer Corporation Length determination of nucleic acid repeat sequences by discontinuous primer extension
US5919626A (en) * 1997-06-06 1999-07-06 Orchid Bio Computer, Inc. Attachment of unmodified nucleic acids to silanized solid phase surfaces
US5916776A (en) * 1997-08-27 1999-06-29 Sarnoff Corporation Amplification method for a polynucleotide
WO2001029248A2 (en) * 1999-10-19 2001-04-26 Bionex, Inc. Method for amplifying and detecting nucleic acid
US6642000B1 (en) * 1999-11-12 2003-11-04 University Of Chicago PCR amplification on microarrays of gel immobilized oligonucleotides
JP2001147230A (ja) 1999-11-19 2001-05-29 Hitachi Software Eng Co Ltd バイオチップ読取装置及び標識試薬
US20030031675A1 (en) 2000-06-06 2003-02-13 Mikesell Glen E. B7-related nucleic acids and polypeptides useful for immunomodulation
DE50012114D1 (de) * 2000-09-05 2006-04-13 Zeltz Patrick Verfahren zur spezifischen Bestimmung von DNA-Sequenzen mittels paralleler Amplifikation
EP1354064A2 (de) 2000-12-01 2003-10-22 Visigen Biotechnologies, Inc. Enzymatische nukleinsäuresynthese: zusammensetzungen und verfahren, um die zuverlässigkeit des monomereinbaus zu erhöhen
AR031640A1 (es) 2000-12-08 2003-09-24 Applied Research Systems Amplificacion isotermica de acidos nucleicos en un soporte solido
EP1950305A1 (de) 2001-05-09 2008-07-30 Monsanto Technology, LLC Tyr-A-Gene und ihre Verwendung
JP2003189869A (ja) * 2001-12-27 2003-07-08 Nisshinbo Ind Inc 被検体中に含まれる生物種を判定する方法およびそれに用いるキット
CN100343389C (zh) * 2002-11-07 2007-10-17 松原洋一 基因突变检出法
US7329490B2 (en) 2003-09-15 2008-02-12 Bristol-Myers Squibb Company Methods for diagnosing schizophrenia by detecting a polymorphism in the KalphaM1 gene
DE102005029810B4 (de) * 2005-06-27 2008-11-13 Siemens Ag Verfahren zum Nachweis von Nukleotidsequenzen, Verwendung des Verfahrens und Testbesteck
JP5155660B2 (ja) * 2005-08-19 2013-03-06 住友ベークライト株式会社 ｃＤＮＡおよびＲＮＡ鎖の製造方法
WO2008093098A2 (en) 2007-02-02 2008-08-07 Illumina Cambridge Limited Methods for indexing samples and sequencing multiple nucleotide templates
KR101376359B1 (ko) 2007-08-01 2014-03-27 다나-파버 캔서 인스티튜트 인크. 표적 서열 강화
WO2009067569A2 (en) 2007-11-20 2009-05-28 E.I. Du Pont De Nemours And Company Plants with altered root architecture, related constructs and methods involving genes encoding leucine rich repeat kinase (llrk) polypeptides and homologs thereof
US8728764B2 (en) 2008-10-02 2014-05-20 Illumina Cambridge Limited Nucleic acid sample enrichment for sequencing applications
US8182994B2 (en) 2009-09-15 2012-05-22 Illumina Cambridge Limited Centroid markers for image analysis of high denisty clusters in complex polynucleotide sequencing
WO2011097215A2 (en) 2010-02-02 2011-08-11 E.I. Du Pont De Nemours And Company Plants with altered root architecture, related constructs and methods involving genes encoding lectin protein kinase (lpk) polypeptides and homologs thereof
CA2792433C (en) 2010-03-08 2016-10-11 Gerassimos Makrigiorgos Full cold-pcr enrichment with reference blocking sequence
CA2830361C (en) 2011-03-31 2021-03-16 Dana-Farber Cancer Institute, Inc. Methods and compositions to enable multiplex cold-pcr
US9133490B2 (en) 2012-05-16 2015-09-15 Transgenomic, Inc. Step-up method for COLD-PCR enrichment
WO2015013166A1 (en) 2013-07-24 2015-01-29 Dana-Farber Cancer Institute, Inc. Methods and compositions to enable enrichment of minor dna alleles by limiting denaturation time in pcr or simply enable enrichment of minor dna alleles by limiting denaturation time in pcr
EP3197269A1 (de) 2014-09-26 2017-08-02 Purecircle Usa Inc. Einzelnukleotidpolymorphismus-marker für stevia
DE102015003951A1 (de) 2015-03-26 2016-09-29 Tokushin Denki Co., Ltd. Rohrschwingungs-Kontrollsystem
JP2018133998A (ja) * 2015-07-03 2018-08-30 株式会社カネカ 標的核酸の検出法
WO2018111835A1 (en) 2016-12-12 2018-06-21 Dana-Farber Cancer Institute, Inc. Compositions and methods for molecular barcoding of dna molecules prior to mutation enrichment and/or mutation detection
WO2018170436A1 (en) 2017-03-16 2018-09-20 Jacobs Farm Del Cabo Basil with high tolerance to downy mildew
US11174511B2 (en) 2017-07-24 2021-11-16 Dana-Farber Cancer Institute, Inc. Methods and compositions for selecting and amplifying DNA targets in a single reaction mixture

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CA1272443A (en) * 1985-02-22 1990-08-07 Nanibhushan Dattagupta Solution-phase dual hybridization assay for detecting polynucleotide sequences
GB8507706D0 (en) * 1985-03-25 1985-05-01 Genetics Int Inc Magnetic nucleic acid sequences

Also Published As

Publication number Publication date
EP0464067A1 (de) 1992-01-08
ATE147791T1 (de) 1997-02-15
AU5272890A (en) 1990-10-22
WO1990011369A1 (en) 1990-10-04
EP0464067B1 (de) 1997-01-15
JP3152656B2 (ja) 2001-04-03
KR920700360A (ko) 1992-02-19
JPH04505999A (ja) 1992-10-22
AU646220B2 (en) 1994-02-17
CA2050681A1 (en) 1990-09-23
DE69029726T2 (de) 1997-09-04

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee