DE69003213D1 - Imidazol-Derivate als Histamin-H3-Agonisten. - Google Patents
Imidazol-Derivate als Histamin-H3-Agonisten.Info
- Publication number
- DE69003213D1 DE69003213D1 DE90307998T DE69003213T DE69003213D1 DE 69003213 D1 DE69003213 D1 DE 69003213D1 DE 90307998 T DE90307998 T DE 90307998T DE 69003213 T DE69003213 T DE 69003213T DE 69003213 D1 DE69003213 D1 DE 69003213D1
- Authority
- DE
- Germany
- Prior art keywords
- histamine
- agonists
- imidazole derivatives
- imidazole
- derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- 229940124806 histamine H3 agonist Drugs 0.000 title 1
- 150000002460 imidazoles Chemical class 0.000 title 1
- 229940079865 intestinal antiinfectives imidazole derivative Drugs 0.000 title 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/415—1,2-Diazoles
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB898916947A GB8916947D0 (en) | 1989-07-25 | 1989-07-25 | Medicaments |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69003213D1 true DE69003213D1 (de) | 1993-10-14 |
DE69003213T2 DE69003213T2 (de) | 1994-01-05 |
Family
ID=10660573
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE90307998T Expired - Fee Related DE69003213T2 (de) | 1989-07-25 | 1990-07-20 | Imidazol-Derivate als Histamin-H3-Agonisten. |
Country Status (5)
Country | Link |
---|---|
US (1) | US5047418A (de) |
EP (1) | EP0420396B1 (de) |
JP (1) | JPH0358924A (de) |
DE (1) | DE69003213T2 (de) |
GB (1) | GB8916947D0 (de) |
Families Citing this family (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5321039A (en) * | 1990-04-13 | 1994-06-14 | Societe Civile Bioprojet | Method of inducing a histamine agonist action on H2 receptors |
FR2660862B1 (fr) * | 1990-04-13 | 1994-09-23 | Bioprojet Soc Civ | Application therapeutique de derives de l'histamine, nouveau derive de l'histamine et utilisation de ces derives pour la preparation de medicaments. |
NL9100365A (nl) * | 1991-02-27 | 1992-09-16 | Seed Capital Investments | Imidazoolderivaten met agonistische of antagonistische activiteit op de histamine h3-receptor. |
GB9115740D0 (en) * | 1991-07-20 | 1991-09-04 | Smithkline Beecham Plc | Medicaments |
SI9300616A (en) * | 1992-11-27 | 1994-06-30 | Wellcome Found | Enzyme inhibitors |
WO1995014007A1 (en) * | 1993-11-15 | 1995-05-26 | Schering Corporation | Phenyl-alkyl imidazoles as h3-receptor antagonists |
US6133291A (en) * | 1998-10-16 | 2000-10-17 | Schering Corporation | N-(imidazolylalkyl)substituted cyclic amines as histamine-H3 agonists or antagonists |
US6211182B1 (en) | 1999-03-08 | 2001-04-03 | Schering Corporation | Imidazole compounds substituted with a six or seven membered heterocyclic ring containing two nitrogen atoms |
DE60135471D1 (de) | 2000-09-20 | 2008-10-02 | Schering Corp | H3 agonisten oder antagonisten |
MXPA03002447A (es) | 2000-09-20 | 2003-07-21 | Schering Corp | Imidazoles sustituidos como agonistas o antagonistas duales h1 y h3 de histamina. |
MXPA03002448A (es) | 2000-09-20 | 2003-06-19 | Schering Corp | Eimidazoles sustituidos como agonistas o antagonistas duales h1 y h3 de histamina. |
JP2004514709A (ja) | 2000-09-20 | 2004-05-20 | シェーリング コーポレイション | ヒスタミンh1およびh3の二重アゴニストまたは二重アンタゴニストとしての置換イミダゾール |
EP1408965A2 (de) | 2001-02-08 | 2004-04-21 | Schering Corporation | Verwendung von h3/m2 antagonisten mit a bipiperidin struktur zur behandlung von wahrnehmungs defizit störung |
JPWO2007032536A1 (ja) * | 2005-09-15 | 2009-03-19 | 萬有製薬株式会社 | 脂質・糖代謝性疾患の治療剤としてのヒスタミンh3アゴニスト |
CN103288742A (zh) * | 2013-06-04 | 2013-09-11 | 四川百利药业有限责任公司 | 一种高纯度英加韦林原料的制备方法 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3891764A (en) * | 1969-10-29 | 1975-06-24 | Smith Kline French Lab | Method of inhibiting histamine activity with amidine derivatives |
US3759944A (en) * | 1970-10-14 | 1973-09-18 | Smith Kline French Lab | Isothioureas and their derivatives |
US3954982A (en) * | 1972-04-20 | 1976-05-04 | Smith Kline & French Laboratories Limited | Pharmaceutical compositions and method of inhibiting H-1 and H-2 histamine receptors |
GB1399283A (en) * | 1972-04-20 | 1975-07-02 | Smith Kline French Lab | Pharmaceutical compositions |
US4000302A (en) * | 1972-04-20 | 1976-12-28 | Smith Kline & French Laboratories Limited | Pharmaceutical compositions and methods of inhibiting H-1 and H-2 histamine receptors |
-
1989
- 1989-07-25 GB GB898916947A patent/GB8916947D0/en active Pending
-
1990
- 1990-07-20 EP EP90307998A patent/EP0420396B1/de not_active Expired - Lifetime
- 1990-07-20 US US07/556,921 patent/US5047418A/en not_active Expired - Fee Related
- 1990-07-20 DE DE90307998T patent/DE69003213T2/de not_active Expired - Fee Related
- 1990-07-24 JP JP2197584A patent/JPH0358924A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
EP0420396A2 (de) | 1991-04-03 |
GB8916947D0 (en) | 1989-09-13 |
EP0420396A3 (en) | 1991-10-16 |
US5047418A (en) | 1991-09-10 |
DE69003213T2 (de) | 1994-01-05 |
JPH0358924A (ja) | 1991-03-14 |
EP0420396B1 (de) | 1993-09-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |