DE68924761T2 - Neue coenzym unabhängige l-sorbosone dehydrogenase. - Google Patents

Neue coenzym unabhängige l-sorbosone dehydrogenase.

Info

Publication number
DE68924761T2
DE68924761T2 DE68924761T DE68924761T DE68924761T2 DE 68924761 T2 DE68924761 T2 DE 68924761T2 DE 68924761 T DE68924761 T DE 68924761T DE 68924761 T DE68924761 T DE 68924761T DE 68924761 T2 DE68924761 T2 DE 68924761T2
Authority
DE
Germany
Prior art keywords
pct
sorbosone
sec
date
sorbosone dehydrogenase
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE68924761T
Other languages
English (en)
Other versions
DE68924761D1 (de
Inventor
Akiko Fujiwara
Tatsuo Hoshino
Masako Dai Ohfuna Park Shinjoh
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of DE68924761D1 publication Critical patent/DE68924761D1/de
Application granted granted Critical
Publication of DE68924761T2 publication Critical patent/DE68924761T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/74—Vectors or expression systems specially adapted for prokaryotic hosts other than E. coli, e.g. Lactobacillus, Micromonospora
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/40—Preparation of oxygen-containing organic compounds containing a carboxyl group including Peroxycarboxylic acids
    • C12P7/58—Aldonic, ketoaldonic or saccharic acids
    • C12P7/60—2-Ketogulonic acid

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE68924761T 1988-01-14 1989-01-09 Neue coenzym unabhängige l-sorbosone dehydrogenase. Expired - Fee Related DE68924761T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP88100419 1988-01-14
PCT/EP1989/000010 WO1989006688A2 (en) 1988-01-14 1989-01-09 Novel enzyme

Publications (2)

Publication Number Publication Date
DE68924761D1 DE68924761D1 (de) 1995-12-14
DE68924761T2 true DE68924761T2 (de) 1996-04-04

Family

ID=8198642

Family Applications (1)

Application Number Title Priority Date Filing Date
DE68924761T Expired - Fee Related DE68924761T2 (de) 1988-01-14 1989-01-09 Neue coenzym unabhängige l-sorbosone dehydrogenase.

Country Status (7)

Country Link
US (1) US5352599A (de)
EP (1) EP0373181B1 (de)
JP (1) JP2799380B2 (de)
AT (1) ATE130030T1 (de)
DE (1) DE68924761T2 (de)
DK (1) DK454689A (de)
WO (1) WO1989006688A2 (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5399496A (en) * 1989-02-02 1995-03-21 Hoffman-Laroche Inc. DNA shuttle vectors for E. coli, Gluconobacter, and Acetobacter
ATE115186T1 (de) * 1989-02-02 1994-12-15 Hoffmann La Roche Pendelvektoren, verwendbar für die mikroorganismen, die zu den escherichia coli, gluconobacter und acetobacter gehören.
IL104419A0 (en) * 1992-01-24 1993-05-13 Fmc Corp Insecticidally effective peptides
US5437989A (en) * 1992-12-30 1995-08-01 Hoffmann-La Roche Inc. Alcohol/aldehyde dehydrogenase from Gluconobacter oxydans DSM 4025 FERM BP-3812
CN1105777C (zh) * 1993-03-08 2003-04-16 藤泽药品工业株式会社 由氧化葡糖杆菌t－100得到的l－山梨糖脱氢酶及其制备方法
WO1995023220A1 (fr) * 1994-02-25 1995-08-31 Fujisawa Pharmaceutical Co., Ltd. Procede de production d'acide 2-ceto-l-gulonique
US5776742A (en) * 1996-02-19 1998-07-07 Roche Vitamins Inc. Aldehyde dehydrogenase enzyme
US6730503B1 (en) 1996-09-19 2004-05-04 Roche Vitamins Inc. Alcohol/aldehyde dehydrogenase
ATE493496T1 (de) 1996-09-19 2011-01-15 Dsm Ip Assets Bv Alkohol-aldehyd-deshydrogenasen
NO981220L (no) * 1997-04-04 1998-10-05 Hoffmann La Roche Cytokrom c samt gen for dette
US6407203B1 (en) 1997-04-04 2002-06-18 Roche Vitamins, Inc. Cytochrome c and polynucleotides encoding cytochrome c
CA2239802A1 (en) 1997-08-21 1999-02-21 F. Hoffmann-La Roche Ag D-sorbitol dehydrogenase gene
US7135315B2 (en) 2002-09-27 2006-11-14 Dsm Ip Assets B.V. Aldehyde dehydrogenase gene
EP2348113B1 (de) 2003-08-14 2016-06-29 DSM IP Assets B.V. Mikrobielle Herstellung von L-Ascorbinsäure
CN100395332C (zh) * 2003-11-28 2008-06-18 华北制药集团有限责任公司 一种l-山梨酮脱氢酶及其编码基因与应用
WO2006084735A1 (en) * 2005-02-11 2006-08-17 Dsm Ip Assets B.V. Gene for coenzyme pqq synthesis protein b from gluconobacter oxydans
CN101292026B (zh) * 2005-09-09 2013-04-24 帝斯曼知识产权资产管理有限公司 新颖的基因gms 08

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3907639A (en) * 1972-08-31 1975-09-23 Hoffmann La Roche Method for producing 2-keto-L-gulonic acid
US5008193A (en) * 1984-06-14 1991-04-16 Genentech, Inc. Ascorbic acid intermediates and process enzymes
DK269987A (da) * 1986-06-03 1987-12-04 Hoffmann La Roche Enzym og fremgangsmaade til fremstilling deraf
DK270087A (da) * 1986-06-03 1987-12-04 Hoffmann La Roche Enzym og fremgangsmaade til fremstilling deraf
US5082785A (en) * 1987-01-30 1992-01-21 Hoffmann-La Roche Inc. Biosynthesis of 2 keto-l-gulonic acid
US5085993A (en) * 1987-12-24 1992-02-04 Hoffmann-La Roche Inc. Coenzyme-independent l-sorbosone dehydrogenase from pseudomonas putida

Also Published As

Publication number Publication date
WO1989006688A3 (en) 1989-09-21
JP2799380B2 (ja) 1998-09-17
EP0373181A1 (de) 1990-06-20
EP0373181B1 (de) 1995-11-08
JPH03500844A (ja) 1991-02-28
DE68924761D1 (de) 1995-12-14
DK454689D0 (da) 1989-09-14
WO1989006688A2 (en) 1989-07-27
US5352599A (en) 1994-10-04
ATE130030T1 (de) 1995-11-15
DK454689A (da) 1989-09-14

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee