DE68901859D1 - 2-benzothiazolamin-derivate enthaltende arzneimittel, verbindungen und ihre herstellung. - Google Patents

2-benzothiazolamin-derivate enthaltende arzneimittel, verbindungen und ihre herstellung.

Info

Publication number
DE68901859D1
DE68901859D1 DE8989403460T DE68901859T DE68901859D1 DE 68901859 D1 DE68901859 D1 DE 68901859D1 DE 8989403460 T DE8989403460 T DE 8989403460T DE 68901859 T DE68901859 T DE 68901859T DE 68901859 D1 DE68901859 D1 DE 68901859D1
Authority
DE
Germany
Prior art keywords
compounds
production
products containing
medicinal products
benzothiazolamine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8989403460T
Other languages
English (en)
Other versions
DE68901859T2 (de
Inventor
Francois Audiau
Claude James
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from FR8816548A external-priority patent/FR2640624B1/fr
Priority claimed from FR8909484A external-priority patent/FR2649705B2/fr
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Application granted granted Critical
Publication of DE68901859D1 publication Critical patent/DE68901859D1/de
Publication of DE68901859T2 publication Critical patent/DE68901859T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/60—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings condensed with carbocyclic rings or ring systems
    • C07D277/62—Benzothiazoles
    • C07D277/68—Benzothiazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
    • C07D277/82—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
DE8989403460T 1988-12-15 1989-12-13 2-benzothiazolamin-derivate enthaltende arzneimittel, verbindungen und ihre herstellung. Expired - Fee Related DE68901859T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8816548A FR2640624B1 (fr) 1988-12-15 1988-12-15 Medicaments a base de derives de la benzothiazolamine-2, nouveaux derives et leur preparation
FR8909484A FR2649705B2 (fr) 1989-07-13 1989-07-13 Medicaments a base de derives de la benzothiazolamine-2, nouveaux derives et leur preparation

Publications (2)

Publication Number Publication Date
DE68901859D1 true DE68901859D1 (de) 1992-07-23
DE68901859T2 DE68901859T2 (de) 1993-01-14

Family

ID=26227051

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8989403460T Expired - Fee Related DE68901859T2 (de) 1988-12-15 1989-12-13 2-benzothiazolamin-derivate enthaltende arzneimittel, verbindungen und ihre herstellung.

Country Status (11)

Country Link
EP (1) EP0374041B1 (de)
JP (1) JPH0749425B2 (de)
CA (1) CA2005592A1 (de)
DE (1) DE68901859T2 (de)
DK (1) DK169383B1 (de)
ES (1) ES2043070T3 (de)
FI (1) FI93108C (de)
GR (1) GR3004937T3 (de)
IE (1) IE64657B1 (de)
NO (1) NO173061C (de)
PT (1) PT92606B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2684993B1 (fr) * 1991-12-13 1994-02-04 Rhone Poulenc Rorer Sa Procede de preparation de derives d'amino-2 nitro-4 benzothiazole et intermediaires.
FR2684992B1 (fr) * 1991-12-13 1994-02-04 Rhone Poulenc Rorer Sa Procede de preparation d'amino-2 nitro-7 benzothiazoles.
FR2714828B1 (fr) * 1994-01-12 1996-02-02 Rhone Poulenc Rorer Sa Application du riluzole dans le traitement des maladies mitochondriales.
FR2726271B1 (fr) * 1994-10-26 1996-12-06 Rhone Poulenc Rorer Sa Derives de 6-polyfluoroalcoxy-2-aminobenzothiazole
FR2741803A1 (fr) * 1995-12-01 1997-06-06 Rhone Poulenc Rorer Sa Application de 2-aminobenzothiazoles dans le traitement de la maladie de parkinson et des syndromes parkinsoniens
US6017903A (en) 1996-09-27 2000-01-25 Guilford Pharmaceuticals Inc. Pharmaceutical compositions and methods of treating a glutamate abnormality and effecting a neuronal activity in an animal using NAALADase inhibitors
US5824662A (en) 1996-09-27 1998-10-20 Guilford Pharmaceuticals Inc. Treatment of global and focal ischemia using naaladase inhibitors
PL332413A1 (en) 1996-09-27 1999-09-13 Guilford Pharm Inc Compositions containing inhibitors of naaladase as well as methods of treating glutamatic anomaly and influencing neuronic functions among animals
FR2774592B1 (fr) * 1998-02-06 2000-03-17 Rhone Poulenc Rorer Sa Application du 2-amino-6-trifluoromethoxybenzothiazole pour la prevention ou le traitement des dysfonctionnements du cervelet
EP1178977B1 (de) 1999-05-12 2005-06-01 Neurosearch A/S Ionenkanal modulierende mittel
WO2003015772A1 (en) * 2001-08-13 2003-02-27 MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V. Inhibitors of polyq-aggregation
JP6991239B2 (ja) 2017-03-30 2022-01-12 エックスダブリューファルマ リミテッド 二環式ヘテロアリール誘導体ならびにその調製および使用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2631163B2 (de) * 1976-07-10 1978-06-29 Basf Ag, 6700 Ludwigshafen Verfahren zur Herstellung von 2-Iminobenzothiazolen
FR2492258A1 (fr) * 1980-10-17 1982-04-23 Pharmindustrie Nouveau medicament a base d'amino-2 trifluoromethoxy-6 benzothiazole
JPS63190880A (ja) * 1986-09-09 1988-08-08 Nippon Tokushu Noyaku Seizo Kk 新規ｎ−ベンゾチアゾリル−アミド類及び殺虫剤
US4826860A (en) * 1987-03-16 1989-05-02 Warner-Lambert Company Substituted 2-aminobenzothiazoles and derivatives useful as cerebrovascular agents

Also Published As

Publication number Publication date
PT92606A (pt) 1990-06-29
IE894008L (en) 1990-06-15
DE68901859T2 (de) 1993-01-14
DK633489D0 (da) 1989-12-14
DK633489A (da) 1990-06-16
NO895032L (no) 1990-06-18
DK169383B1 (da) 1994-10-17
GR3004937T3 (de) 1993-04-28
FI93108C (fi) 1995-02-27
NO173061B (no) 1993-07-12
EP0374041A1 (de) 1990-06-20
FI93108B (fi) 1994-11-15
EP0374041B1 (de) 1992-06-17
NO173061C (no) 1993-10-20
ES2043070T3 (es) 1993-12-16
NO895032D0 (no) 1989-12-14
JPH02223571A (ja) 1990-09-05
IE64657B1 (en) 1995-08-23
JPH0749425B2 (ja) 1995-05-31
FI895983A0 (fi) 1989-12-14
CA2005592A1 (fr) 1990-06-15
PT92606B (pt) 1995-09-12

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee