DE60232898D1 - Hochkomprimierbare ethylcellulose zur tablettierung - Google Patents
Hochkomprimierbare ethylcellulose zur tablettierungInfo
- Publication number
- DE60232898D1 DE60232898D1 DE60232898T DE60232898T DE60232898D1 DE 60232898 D1 DE60232898 D1 DE 60232898D1 DE 60232898 T DE60232898 T DE 60232898T DE 60232898 T DE60232898 T DE 60232898T DE 60232898 D1 DE60232898 D1 DE 60232898D1
- Authority
- DE
- Germany
- Prior art keywords
- tableting
- ethyl cellulose
- highly compressible
- compressible
- highly
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/06—Anti-spasmodics, e.g. drugs for colics, esophagic dyskinesia
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- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
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- A61P9/12—Antihypertensives
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US09/977,785 US6592901B2 (en) | 2001-10-15 | 2001-10-15 | Highly compressible ethylcellulose for tableting |
PCT/US2002/032049 WO2003032955A1 (en) | 2001-10-15 | 2002-10-08 | Highly compressible ethylcellulose for tableting |
Publications (1)
Publication Number | Publication Date |
---|---|
DE60232898D1 true DE60232898D1 (de) | 2009-08-20 |
Family
ID=25525513
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60232898T Expired - Lifetime DE60232898D1 (de) | 2001-10-15 | 2002-10-08 | Hochkomprimierbare ethylcellulose zur tablettierung |
Country Status (12)
Country | Link |
---|---|
US (1) | US6592901B2 (de) |
EP (1) | EP1435918B1 (de) |
JP (1) | JP4672981B2 (de) |
KR (1) | KR20050034612A (de) |
CN (1) | CN100482280C (de) |
BR (1) | BR0213288A (de) |
CA (1) | CA2463583C (de) |
DE (1) | DE60232898D1 (de) |
ES (1) | ES2325986T3 (de) |
MX (1) | MXPA04003378A (de) |
RU (1) | RU2396072C2 (de) |
WO (1) | WO2003032955A1 (de) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7776314B2 (en) | 2002-06-17 | 2010-08-17 | Grunenthal Gmbh | Abuse-proofed dosage system |
US8075872B2 (en) | 2003-08-06 | 2011-12-13 | Gruenenthal Gmbh | Abuse-proofed dosage form |
DE102005005446A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Bruchfeste Darreichungsformen mit retardierter Freisetzung |
US20070048228A1 (en) | 2003-08-06 | 2007-03-01 | Elisabeth Arkenau-Maric | Abuse-proofed dosage form |
DE102004032051A1 (de) * | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten, festen Darreichungsform |
BR122018068298B8 (pt) * | 2003-08-06 | 2021-07-27 | Gruenenthal Gmbh | processo para a produção de um comprimido seguro contra abuso termo-moldado por extrusão sem descoramento |
DE10361596A1 (de) | 2003-12-24 | 2005-09-29 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
DE10336400A1 (de) | 2003-08-06 | 2005-03-24 | Grünenthal GmbH | Gegen Missbrauch gesicherte Darreichungsform |
US7201920B2 (en) | 2003-11-26 | 2007-04-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
ATE493973T1 (de) | 2004-06-04 | 2011-01-15 | Teva Pharma | Irbesartan enthaltende pharmazeutische zusammensetzung |
DE102004032049A1 (de) | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
DE102004032103A1 (de) * | 2004-07-01 | 2006-01-19 | Grünenthal GmbH | Gegen Missbrauch gesicherte, orale Darreichungsform |
US20060068009A1 (en) * | 2004-09-30 | 2006-03-30 | Scolr Pharma, Inc. | Modified release ibuprofen dosage form |
US20070077297A1 (en) | 2004-09-30 | 2007-04-05 | Scolr Pharma, Inc. | Modified release ibuprofen dosage form |
US20090208579A1 (en) * | 2004-12-27 | 2009-08-20 | Eisai R & D Management Co., Ltd. | Matrix Type Sustained-Release Preparation Containing Basic Drug or Salt Thereof, and Method for Manufacturing the Same |
US20070129402A1 (en) * | 2004-12-27 | 2007-06-07 | Eisai Research Institute | Sustained release formulations |
US20060280789A1 (en) * | 2004-12-27 | 2006-12-14 | Eisai Research Institute | Sustained release formulations |
US20060246003A1 (en) * | 2004-12-27 | 2006-11-02 | Eisai Co. Ltd. | Composition containing anti-dementia drug |
CA2592605C (en) * | 2004-12-27 | 2010-12-07 | Eisai R&D Management Co., Ltd. | Method for stabilizing anti-dementia drug |
DE102005005449A1 (de) | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
ZA200807571B (en) | 2006-03-01 | 2009-08-26 | Ethypharm Sa | Crush-resistant tablets intended to prevent accidental misuse and unlawful diversion |
US7749537B2 (en) * | 2006-12-04 | 2010-07-06 | Scolr Pharma, Inc. | Method of forming a tablet |
DE102007011485A1 (de) | 2007-03-07 | 2008-09-11 | Grünenthal GmbH | Darreichungsform mit erschwertem Missbrauch |
US8309129B2 (en) | 2007-05-03 | 2012-11-13 | Bend Research, Inc. | Nanoparticles comprising a drug, ethylcellulose, and a bile salt |
US8703204B2 (en) | 2007-05-03 | 2014-04-22 | Bend Research, Inc. | Nanoparticles comprising a cholesteryl ester transfer protein inhibitor and anon-ionizable polymer |
MX2009011973A (es) * | 2007-05-08 | 2009-12-10 | Hercules Inc | Formulacion robusta de tabletas que se desintegran con rapidez. |
WO2008149230A2 (en) | 2007-06-04 | 2008-12-11 | Pfizer Products Inc. | Nanoparticles comprising drug, a non-ionizable cellulosic polymer and tocopheryl polyethylene glycol succinate |
WO2008149192A2 (en) | 2007-06-04 | 2008-12-11 | Pfizer Products Inc. | Nanoparticles comprising a non-ionizable cellulosic polymer and an amphiphilic non-ionizable block copolymer |
US9724362B2 (en) | 2007-12-06 | 2017-08-08 | Bend Research, Inc. | Pharmaceutical compositions comprising nanoparticles and a resuspending material |
US9233078B2 (en) | 2007-12-06 | 2016-01-12 | Bend Research, Inc. | Nanoparticles comprising a non-ionizable polymer and an Amine-functionalized methacrylate copolymer |
TWI454288B (zh) | 2008-01-25 | 2014-10-01 | Gruenenthal Chemie | 藥物劑型 |
SI2273983T1 (sl) | 2008-05-09 | 2016-11-30 | Gruenenthal Gmbh | Postopek za pripravo intermediatne praškaste formulacije in končne trdne odmerne oblike z uporabo stopnje strjevanja z razprševanjem |
WO2009157564A1 (ja) * | 2008-06-26 | 2009-12-30 | 旭化成ケミカルズ株式会社 | セルロース組成物 |
US20100260842A1 (en) * | 2009-04-06 | 2010-10-14 | Rashmi Nair | Pseudoephedrine pharmaceutical formulations |
JP5667183B2 (ja) | 2009-07-22 | 2015-02-12 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 加熱溶融押出成型した制御放出性投与剤型 |
JP2012533585A (ja) | 2009-07-22 | 2012-12-27 | グリュネンタール・ゲゼルシャフト・ミト・ベシュレンクテル・ハフツング | 酸化感受性オピオイドのための不正使用防止剤形 |
ES2569925T3 (es) * | 2009-09-30 | 2016-05-13 | Acura Pharmaceuticals, Inc. | Métodos y composiciones de disuasión del abuso |
US9579285B2 (en) | 2010-02-03 | 2017-02-28 | Gruenenthal Gmbh | Preparation of a powdery pharmaceutical composition by means of an extruder |
US9636303B2 (en) | 2010-09-02 | 2017-05-02 | Gruenenthal Gmbh | Tamper resistant dosage form comprising an anionic polymer |
ES2486791T3 (es) | 2010-09-02 | 2014-08-19 | Grünenthal GmbH | Forma de dosificación resistente a la manipulación que comprende una sal inorgánica |
TWI535461B (zh) | 2011-03-11 | 2016-06-01 | 諾金私人有限公司 | 結腸清潔溶液、用於製備該溶液之組成物、包含該組成物或溶液之套組、與製備該溶液之方法 |
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US10064945B2 (en) | 2012-05-11 | 2018-09-04 | Gruenenthal Gmbh | Thermoformed, tamper-resistant pharmaceutical dosage form containing zinc |
EP2679098B1 (de) * | 2012-06-26 | 2017-08-09 | DMK Deutsches Milchkontor GmbH | Milchpulver mit hohem molkenproteinindex |
ES2909386T3 (es) | 2012-09-11 | 2022-05-06 | Norgine Bv | Composiciones que comprenden polietilenglicol y sulfatos de metales alcalinos o alcalinotérreos para su uso como composiciones de limpieza de colon |
RU2673818C2 (ru) | 2012-11-30 | 2018-11-30 | Экьюра Фармасьютикалз, Инк. | Саморегулируемое высвобождение фармацевтического ингредиента |
WO2014191396A1 (en) | 2013-05-29 | 2014-12-04 | Grünenthal GmbH | Tamper resistant dosage form with bimodal release profile |
BR112015026549A2 (pt) | 2013-05-29 | 2017-07-25 | Gruenenthal Gmbh | forma de dosagem à prova de violação contendo uma ou mais partículas |
CN105682643B (zh) | 2013-07-12 | 2019-12-13 | 格吕伦塔尔有限公司 | 含有乙烯-醋酸乙烯酯聚合物的防篡改剂型 |
CA2931553C (en) | 2013-11-26 | 2022-01-18 | Grunenthal Gmbh | Preparation of a powdery pharmaceutical composition by means of cryo-milling |
US9642811B2 (en) | 2014-03-26 | 2017-05-09 | Sun Pharma Advanced Research Company Ltd. | Abuse deterrent immediate release biphasic matrix solid dosage form |
AU2015266117A1 (en) | 2014-05-26 | 2016-11-24 | Grunenthal Gmbh | Multiparticles safeguarded against ethanolic dose-dumping |
MX2017013637A (es) | 2015-04-24 | 2018-03-08 | Gruenenthal Gmbh | Forma de dosificacion resistente a alteraciones con liberacion inmediata y resistencia contra la extraccion por solventes. |
US11103581B2 (en) | 2015-08-31 | 2021-08-31 | Acura Pharmaceuticals, Inc. | Methods and compositions for self-regulated release of active pharmaceutical ingredient |
US10842750B2 (en) | 2015-09-10 | 2020-11-24 | Grünenthal GmbH | Protecting oral overdose with abuse deterrent immediate release formulations |
EP3492519B1 (de) * | 2016-07-29 | 2020-12-09 | New Japan Chemical Co., Ltd. | Kristallines nukleierungsmittel für polyolefinharz, verfahren zur herstellung eines kristallinen nukleierungsmittels für polyolefinharz und verfahren zur verbesserung der fliessfähigkeit eines kristallinen nukleierungsmittel für polyolefinharz |
EP3514201A4 (de) | 2016-09-16 | 2020-05-06 | New Japan Chemical Co., Ltd. | Kristallines nukleierungsmittel für polyolefinharze, verfahren zur herstellung eines kristallinen nukleierungsmittels für polyolefinharze und verfahren zur verbesserung der fliessfähigkeit eines kristallinen nukleierungsmittels für polyolefinharze |
FR3064639B1 (fr) | 2017-03-30 | 2020-07-24 | Eurenco France | Films d'ethylcellulose et blocs de propergol double-base inhibes en combustion avec de tels films |
GB2571696B (en) | 2017-10-09 | 2020-05-27 | Compass Pathways Ltd | Large scale method for the preparation of Psilocybin and formulations of Psilocybin so produced |
US10537585B2 (en) | 2017-12-18 | 2020-01-21 | Dexcel Pharma Technologies Ltd. | Compositions comprising dexamethasone |
JP2022515069A (ja) * | 2018-12-18 | 2022-02-17 | ニュートリション アンド バイオサイエンシズ ユーエスエー 1,リミティド ライアビリティ カンパニー | エチルセルロースを含む徐放性組成物 |
WO2020212948A1 (en) | 2019-04-17 | 2020-10-22 | Compass Pathfinder Limited | Methods of treating neurocognitive disorders, chronic pain and reducing inflammation |
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US3870790A (en) * | 1970-01-22 | 1975-03-11 | Forest Laboratories | Solid pharmaceutical formulations containing hydroxypropyl methyl cellulose |
DE3508097A1 (de) * | 1984-07-21 | 1986-02-06 | Hoechst Ag, 6230 Frankfurt | Kombinationspraeparat aus xanthinderivaten und o-acetylsalicylsaeure bzw. deren pharmakologisch vertraeglichen salzen und dessen verwendung |
US4710384A (en) * | 1986-07-28 | 1987-12-01 | Avner Rotman | Sustained release tablets made from microcapsules |
IT1200217B (it) * | 1986-09-30 | 1989-01-05 | Valducci Roberto | Membrana per uso farmaceutico ed industriale |
JP2697738B2 (ja) * | 1988-02-26 | 1998-01-14 | マックダーミッド イメージング テクノロジー,インコーポレイテッド | 光重合可能な組成物 |
US5082669A (en) * | 1989-07-20 | 1992-01-21 | Dainippon Pharmaceutical Co., Ltd. | Rapid-releasing oral particle pharmaceutical preparation with unpleasant taste masked |
MX9200700A (es) * | 1991-02-27 | 1992-08-01 | Boehringer Ingelheim Kg | Solucion de laca retardante para preparaciones farmaceuticas. |
JP4194114B2 (ja) * | 1994-02-23 | 2008-12-10 | ビーエム リサーチ エイ/エス | 制御放出組成物 |
DE69617708T2 (de) * | 1995-09-15 | 2002-08-08 | Marconi Data Systems Inc | Tintenstrahltinte |
-
2001
- 2001-10-15 US US09/977,785 patent/US6592901B2/en not_active Expired - Lifetime
-
2002
- 2002-10-08 CN CNB028204050A patent/CN100482280C/zh not_active Expired - Fee Related
- 2002-10-08 RU RU2004115021/15A patent/RU2396072C2/ru not_active IP Right Cessation
- 2002-10-08 CA CA002463583A patent/CA2463583C/en not_active Expired - Fee Related
- 2002-10-08 DE DE60232898T patent/DE60232898D1/de not_active Expired - Lifetime
- 2002-10-08 ES ES02776176T patent/ES2325986T3/es not_active Expired - Lifetime
- 2002-10-08 KR KR1020047005473A patent/KR20050034612A/ko not_active Application Discontinuation
- 2002-10-08 BR BR0213288-5A patent/BR0213288A/pt not_active Application Discontinuation
- 2002-10-08 JP JP2003535759A patent/JP4672981B2/ja not_active Expired - Fee Related
- 2002-10-08 MX MXPA04003378A patent/MXPA04003378A/es active IP Right Grant
- 2002-10-08 WO PCT/US2002/032049 patent/WO2003032955A1/en active Application Filing
- 2002-10-08 EP EP02776176A patent/EP1435918B1/de not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1571662A (zh) | 2005-01-26 |
JP4672981B2 (ja) | 2011-04-20 |
ES2325986T3 (es) | 2009-09-28 |
JP2005509620A (ja) | 2005-04-14 |
KR20050034612A (ko) | 2005-04-14 |
US20030077327A1 (en) | 2003-04-24 |
RU2004115021A (ru) | 2005-04-20 |
EP1435918A1 (de) | 2004-07-14 |
MXPA04003378A (es) | 2004-06-18 |
BR0213288A (pt) | 2004-11-23 |
CA2463583A1 (en) | 2003-04-24 |
US6592901B2 (en) | 2003-07-15 |
RU2396072C2 (ru) | 2010-08-10 |
EP1435918B1 (de) | 2009-07-08 |
CA2463583C (en) | 2009-09-15 |
WO2003032955A1 (en) | 2003-04-24 |
CN100482280C (zh) | 2009-04-29 |
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