MX2009011973A - Formulacion robusta de tabletas que se desintegran con rapidez. - Google Patents
Formulacion robusta de tabletas que se desintegran con rapidez.Info
- Publication number
- MX2009011973A MX2009011973A MX2009011973A MX2009011973A MX2009011973A MX 2009011973 A MX2009011973 A MX 2009011973A MX 2009011973 A MX2009011973 A MX 2009011973A MX 2009011973 A MX2009011973 A MX 2009011973A MX 2009011973 A MX2009011973 A MX 2009011973A
- Authority
- MX
- Mexico
- Prior art keywords
- tablet formulation
- disintegration tablet
- rapid disintegration
- disintegration time
- robust
- Prior art date
Links
Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/10—Laxatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/12—Antidiarrhoeals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Epidemiology (AREA)
- Diabetes (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Physiology (AREA)
- Nutrition Science (AREA)
- Pain & Pain Management (AREA)
- Zoology (AREA)
- Psychiatry (AREA)
- Hematology (AREA)
- Psychology (AREA)
- Hospice & Palliative Care (AREA)
- Anesthesiology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Rheumatology (AREA)
- Obesity (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
La presente invención se refiere a una tableta o forma de dosificación comprimida, para administración por vía oral, de desintegración rápida, que contiene etilcelulosa (EC) como aglutinante para compresión directa, el cual mejora la robustez de la tableta, tal y como se manifiesta por su mejor resistencia, menor friabilidad, menor higroscopicidad y todavía, no obstante su naturaleza hidrófoba, no retarda el tiempo de desintegración, sino lo acorta, o tiene un tiempo de desintegración neutro cuando se co-formula con agentes desintegrantes y otros excipientes solubles en agua, como los alcoholes de azúcar.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US92812507P | 2007-05-08 | 2007-05-08 | |
PCT/US2008/005978 WO2008140772A2 (en) | 2007-05-08 | 2008-05-08 | Robust rapid disintegration tablet formulation |
Publications (1)
Publication Number | Publication Date |
---|---|
MX2009011973A true MX2009011973A (es) | 2009-12-10 |
Family
ID=39660764
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
MX2009011973A MX2009011973A (es) | 2007-05-08 | 2008-05-08 | Formulacion robusta de tabletas que se desintegran con rapidez. |
Country Status (10)
Country | Link |
---|---|
US (1) | US20080305166A1 (es) |
EP (1) | EP2155159B1 (es) |
JP (1) | JP2010526811A (es) |
CN (1) | CN101677945A (es) |
BR (1) | BRPI0811303A2 (es) |
CA (1) | CA2686035C (es) |
ES (1) | ES2745438T3 (es) |
MX (1) | MX2009011973A (es) |
RU (1) | RU2472493C2 (es) |
WO (1) | WO2008140772A2 (es) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7201920B2 (en) | 2003-11-26 | 2007-04-10 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse of opioid containing dosage forms |
CN103919742B (zh) * | 2008-11-25 | 2017-04-12 | 田边三菱制药株式会社 | 口腔速崩片及其制备方法 |
EP2488029B1 (en) | 2009-09-30 | 2016-03-23 | Acura Pharmaceuticals, Inc. | Methods and compositions for deterring abuse |
CN101978953A (zh) * | 2010-10-11 | 2011-02-23 | 上海交通大学 | 基于易吸湿性辅料的固体制剂 |
US9204667B2 (en) * | 2010-12-01 | 2015-12-08 | R.J. Reynolds Tobacco Company | Smokeless tobacco pastille and injection molding process for forming smokeless tobacco products |
CN103415284B (zh) * | 2011-03-09 | 2016-12-07 | 巴斯夫欧洲公司 | 用于制备快速崩解的片剂的药物配制物 |
CA2853117C (en) * | 2011-10-25 | 2018-08-07 | Expermed S.A. | Sublingual pharmaceutical composition containing an antihistamine agent and method for the preparation thereof |
CN103385859A (zh) * | 2012-05-08 | 2013-11-13 | 中国人民解放军***总医院 | 一种治疗创伤后应激障碍症的盐酸***口腔崩解片及其制备方法 |
CN104968333B (zh) | 2012-11-30 | 2018-07-10 | 阿库拉制药公司 | 活性药物成分的自调节释放 |
CA2943728C (en) | 2014-03-26 | 2020-03-24 | Sun Pharma Advanced Research Company Ltd. | Abuse deterrent immediate release biphasic matrix solid dosage form |
JP2016195557A (ja) * | 2015-04-03 | 2016-11-24 | 富士フイルム株式会社 | 植物発酵物を含む錠剤及びその製造方法 |
EP3288556A4 (en) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
WO2017040607A1 (en) | 2015-08-31 | 2017-03-09 | Acura Pharmaceuticals, Inc. | Methods and compositions for self-regulated release of active pharmaceutical ingredient |
DK3395342T3 (da) | 2015-12-25 | 2020-10-12 | Fujifilm Toyama Chemical Co Ltd | Tablet omfattende 1-(3-(2-(1-benzothiophen-5-YL)ethoxy)propyl)azetidin-3-ol eller salt deraf |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
JP6762898B2 (ja) * | 2017-03-23 | 2020-09-30 | 共和薬品工業株式会社 | ガランタミン臭化水素酸塩含有口腔内崩壊錠 |
US10537585B2 (en) | 2017-12-18 | 2020-01-21 | Dexcel Pharma Technologies Ltd. | Compositions comprising dexamethasone |
CN108309948B (zh) * | 2018-05-11 | 2019-12-06 | 新华制药(高密)有限公司 | 盐酸西替利嗪片及其制备方法 |
CN111202716B (zh) * | 2018-11-05 | 2021-10-26 | 广州白云山光华制药股份有限公司 | 茶碱缓释片及其制备方法 |
TWI724629B (zh) * | 2018-11-16 | 2021-04-11 | 日商協和化學工業股份有限公司 | 緩瀉用錠劑 |
Family Cites Families (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA2166891C (en) * | 1993-07-09 | 2001-07-03 | Sang K. Wong | Method for making freeze dried drug dosage forms |
ES2082723B1 (es) * | 1994-07-20 | 1996-10-01 | Lilly Sa | Formulacion farmaceutica de fluoxetina en forma dispersable. |
US5585115A (en) * | 1995-01-09 | 1996-12-17 | Edward H. Mendell Co., Inc. | Pharmaceutical excipient having improved compressability |
US5780055A (en) * | 1996-09-06 | 1998-07-14 | University Of Maryland, Baltimore | Cushioning beads and tablet comprising the same capable of forming a suspension |
IT1293764B1 (it) * | 1997-07-23 | 1999-03-10 | Chiesi Farma Spa | Composizioni farmaceutiche sotto forma di compresse effervescenti contenenti un principio attivo instabile in presenza di acqua |
EP1054019A1 (en) * | 1999-05-18 | 2000-11-22 | Shin-Etsu Chemical Co., Ltd. | Low-substituted hydroxypropyl cellulose |
CA2311734C (en) * | 2000-04-12 | 2011-03-08 | Bristol-Myers Squibb Company | Flash-melt oral dosage formulation |
FR2824477B1 (fr) * | 2001-05-09 | 2005-09-09 | Ethypharm Lab Prod Ethiques | Granules enrobes a base d'inhibiteur de l'enzyme de conversion de l'anfiotensine, leur procede de preparation et comprimes orodispersibles contenant les granules enrobes |
TWI324074B (en) * | 2001-10-09 | 2010-05-01 | Bristol Myers Squibb Co | Flashmelt oral dosage formulation |
US6592901B2 (en) * | 2001-10-15 | 2003-07-15 | Hercules Incorporated | Highly compressible ethylcellulose for tableting |
US6610266B2 (en) * | 2001-11-28 | 2003-08-26 | Michael C. Withiam | Calcium metasilicates and methods for making |
WO2003075830A2 (en) * | 2002-03-14 | 2003-09-18 | Sun Pharmaceutical Industries Limited | Oral controlled drug delivery system containing carbamazepine |
US6846497B2 (en) * | 2003-01-30 | 2005-01-25 | National Starch And Chemical Investment Holding Corporation | Rapidly expanding starches with altered crystalline structure |
US20050244343A1 (en) * | 2004-04-30 | 2005-11-03 | Withiam Michael C | Oral care products comprising silica |
JP2005343800A (ja) * | 2004-05-31 | 2005-12-15 | Lion Corp | 被覆カフェイン粒子、固形製剤および眠気防止薬 |
JP2008526827A (ja) * | 2005-01-07 | 2008-07-24 | ファイザー・プロダクツ・インク | 5,8,14−トリアザテトラシクロ[10.3.1.02,11.04,9]−ヘキサデカ−2(11),3,5,7,9−ペンタエンの速崩壊性投与形態 |
-
2008
- 2008-05-08 CA CA2686035A patent/CA2686035C/en active Active
- 2008-05-08 ES ES08767661T patent/ES2745438T3/es active Active
- 2008-05-08 RU RU2009145167/15A patent/RU2472493C2/ru active
- 2008-05-08 MX MX2009011973A patent/MX2009011973A/es not_active Application Discontinuation
- 2008-05-08 US US12/151,695 patent/US20080305166A1/en not_active Abandoned
- 2008-05-08 JP JP2010507472A patent/JP2010526811A/ja active Pending
- 2008-05-08 BR BRPI0811303-3A2A patent/BRPI0811303A2/pt not_active Application Discontinuation
- 2008-05-08 WO PCT/US2008/005978 patent/WO2008140772A2/en active Application Filing
- 2008-05-08 CN CN200880019353A patent/CN101677945A/zh active Pending
- 2008-05-08 EP EP08767661.5A patent/EP2155159B1/en active Active
Also Published As
Publication number | Publication date |
---|---|
JP2010526811A (ja) | 2010-08-05 |
US20080305166A1 (en) | 2008-12-11 |
RU2472493C2 (ru) | 2013-01-20 |
CA2686035A1 (en) | 2008-11-20 |
CA2686035C (en) | 2016-01-05 |
WO2008140772A2 (en) | 2008-11-20 |
ES2745438T3 (es) | 2020-03-02 |
EP2155159A2 (en) | 2010-02-24 |
EP2155159B1 (en) | 2019-07-10 |
BRPI0811303A2 (pt) | 2015-01-27 |
WO2008140772A3 (en) | 2009-09-24 |
CN101677945A (zh) | 2010-03-24 |
RU2009145167A (ru) | 2011-06-20 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
HH | Correction or change in general | ||
FA | Abandonment or withdrawal |