DE60218704D1 - 6,7-DIHYDRO-5H-PYRAZOLOi1,2-Aö PYRAZOL-1-ONE ZUR KONTROLLE VON ENTZÜNDUNGSFÖRDERNDEN CYTOKINEN - Google Patents

6,7-DIHYDRO-5H-PYRAZOLOi1,2-Aö PYRAZOL-1-ONE ZUR KONTROLLE VON ENTZÜNDUNGSFÖRDERNDEN CYTOKINEN

Info

Publication number: DE60218704D1
Authority: DE; Germany
Prior art keywords: pyrazoloi1; pyrazol; dihydro; control; inflammatory cytokines
Prior art date: 2001-09-20
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Lifetime

Application number

DE60218704T

Other languages

English (en)

Other versions

DE60218704T2 (de

Inventor

Michael Phillip Clark

Matthew John Laufersweiler

Jane Far-Jine Djung

Michael George Natchus

Biswanath De

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Procter and Gamble Co

Original Assignee

Procter and Gamble Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2001-09-20

Filing date

2002-09-20

Publication date

2007-04-19

2002-09-20 Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co

2007-04-19 Publication of DE60218704D1 publication Critical patent/DE60218704D1/de

2007-11-08 Application granted granted Critical

2007-11-08 Publication of DE60218704T2 publication Critical patent/DE60218704T2/de

2022-09-21 Anticipated expiration legal-status Critical

Status Expired - Lifetime legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/12—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains three hetero rings
- C07D491/20—Spiro-condensed systems
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
- C07D495/20—Spiro-condensed systems

DE60218704T 2001-09-20 2002-09-20 6,7-dihydro-5h-pyrazolo1,2-a pyrazol-1-one zur kontrolle von entzündungsfördernden cytokinen Expired - Lifetime DE60218704T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
US32362501P	2001-09-20	2001-09-20
US323625P		2001-09-20
PCT/US2002/030135 WO2003024971A1 (en)	2001-09-20	2002-09-20	6,7-dihydro-5h-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines

Publications (2)

Publication Number	Publication Date
DE60218704D1 true DE60218704D1 (de)	2007-04-19
DE60218704T2 DE60218704T2 (de)	2007-11-08

Family

ID=23259997

Family Applications (3)

Application Number	Title	Priority Date	Filing Date
DE60202782T Expired - Lifetime DE60202782T2 (de)	2001-09-20	2002-09-20	Verbindungen, welche die freisetzung von cytokinen inhibieren
DE60213108T Expired - Fee Related DE60213108T2 (de)	2001-09-20	2002-09-20	SPIROCYCLISCHE 6,7-DIHYDRO-5H-PYRAZOLOc1,2-AÜPYRAZOL-1-ONE, DIE INFLAMMATORISCHE CYTOKINE STEUERN
DE60218704T Expired - Lifetime DE60218704T2 (de)	2001-09-20	2002-09-20	6,7-dihydro-5h-pyrazolo1,2-a pyrazol-1-one zur kontrolle von entzündungsfördernden cytokinen

Family Applications Before (2)

Application Number	Title	Priority Date	Filing Date
DE60202782T Expired - Lifetime DE60202782T2 (de)	2001-09-20	2002-09-20	Verbindungen, welche die freisetzung von cytokinen inhibieren
DE60213108T Expired - Fee Related DE60213108T2 (de)	2001-09-20	2002-09-20	SPIROCYCLISCHE 6,7-DIHYDRO-5H-PYRAZOLOc1,2-AÜPYRAZOL-1-ONE, DIE INFLAMMATORISCHE CYTOKINE STEUERN

Country Status (33)

Country	Link
US (2)	US6821971B2 (de)
EP (3)	EP1427728B1 (de)
JP (3)	JP2005504081A (de)
KR (4)	KR20040035837A (de)
CN (3)	CN1257905C (de)
AR (3)	AR037145A1 (de)
AT (3)	ATE356126T1 (de)
AU (2)	AU2002334641B2 (de)
BR (3)	BR0212905A (de)
CA (3)	CA2461071A1 (de)
CO (3)	CO5560590A2 (de)
CY (1)	CY1106398T1 (de)
CZ (3)	CZ2004361A3 (de)
DE (3)	DE60202782T2 (de)
DK (2)	DK1427732T3 (de)
EG (2)	EG24363A (de)
ES (3)	ES2282459T3 (de)
HK (2)	HK1071366A1 (de)
HU (3)	HUP0402500A3 (de)
IL (3)	IL160682A0 (de)
MA (3)	MA27064A1 (de)
MX (3)	MXPA04002574A (de)
MY (2)	MY129329A (de)
NO (2)	NO20041594L (de)
NZ (3)	NZ531063A (de)
PE (3)	PE20030474A1 (de)
PL (3)	PL370362A1 (de)
PT (3)	PT1427727E (de)
RU (3)	RU2299885C2 (de)
SA (1)	SA03230529B1 (de)
SK (3)	SK1482004A3 (de)
WO (3)	WO2003024971A1 (de)
ZA (3)	ZA200401260B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
US6730668B2 (en) *	2001-09-20	2004-05-04	The Procter & Gamble Company	6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines
US7087615B2 (en)	2001-09-20	2006-08-08	The Procter & Gamble Company	6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which provide analgesia
US6849627B2 (en)	2001-09-20	2005-02-01	The Procter & Gamble Company	6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines
US7473695B2 (en)	2001-10-22	2009-01-06	Mitsubishi Tanabe Pharma Corporation	4-imidazolin-2-one compounds
US6677337B2 (en) *	2002-03-19	2004-01-13	The Procter & Gamble Company	1,2-dihydropyrazol-3-ones which controls inflammatory cytokines
ATE355839T1 (de) *	2002-09-09	2007-03-15	Amgen Inc	1,4,5-substituierte 1,2-dihydro-pyrazol-3-one and 3-alkoxy-1h-pyrazole derivate als tnf-alpha und interleukin senkende wirkstoffe zur behandlung von entzündungen
ES2285444T3 (es) *	2003-04-03	2007-11-16	Merck Patent Gmbh	Derivados de la 1-(fenil)-amida)-2-(fenil)-amida) del acido pirazolidin-1,2-dicarboxilico como inhibidores del factor de coagulacion xa para el tratamiento de la trombosis.
GB0308466D0 (en) *	2003-04-11	2003-05-21	Novartis Ag	Organic compounds
US7482356B2 (en) *	2003-11-10	2009-01-27	The Procter & Gamble Company	Bicyclic pyrazolone cytokine inhibitors
RU2450006C2 (ru) *	2006-04-18	2012-05-10	Эбботт Лэборетриз	Антагонисты ванилоидного рецептора подтипа 1(vr1) и их применение
DE102008060549A1 (de)	2008-12-04	2010-06-10	MAX-PLANCK-Gesellschaft zur Förderung der Wissenschaften e.V.	Wirkstoff-Peptid-Konstrukt zur extrazellulären Anreicherung
RU2011151603A (ru) *	2009-05-19	2013-06-27	ДАУ АГРОСАЙЕНСИЗ ЭлЭсСи	Соединения и способы борьбы с грибами
EP3308059B1 (de)	2015-06-15	2021-05-26	Cummins, Inc.	Brennraumelastizitätsvorrichtung
US20190060286A1 (en)	2016-02-29	2019-02-28	University Of Florida Research Foundation, Incorpo	Chemotherapeutic Methods
CN107033090B (zh) *	2017-05-16	2019-05-07	无锡捷化医药科技有限公司	一种1,2,3,4-四氢噌啉的制备方法
RU2721684C1 (ru) *	2019-09-06	2020-05-21	Федеральное государственное бюджетное образовательное учреждение высшего образования "Пермский государственный национальный исследовательский университет"	Метил 2,3,8-триоксо-4-фенилтетрагидро-6Н-пиразоло[1,2-а]пирроло[2,3-c]пиразол-9а(1Н)-карбоксилаты
WO2023076133A1 (en) *	2021-10-27	2023-05-04	Merck Sharp & Dohme Llc	Spirotricycle ripk1 inhibitors and methods of uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB1054291A (de)	1963-02-26
GB1124982A (en) *	1965-02-09	1968-08-21	Lepetit Spa	Diazabicyclo octanes and derivatives thereof
CH529154A (fr)	1969-10-27	1972-10-15	Lepetit Spa	Procédé de préparation de pyrazolo (1,2-b) phtalazine-1,5 (10H)-diones
US5358924A (en) *	1991-03-21	1994-10-25	Bayer Aktiengesellschaft	3-hydroxy-4-aryl-5-oxo-pyrozoline derivatives, compositions and use
RU2269537C2 (ru) *	1999-09-07	2006-02-10	Зингента Партисипейшнс Аг	Фенилзамещенные гетероциклические 1,3-кетоенолы, способ их получения, гербицидное средство на их основе и способ борьбы с ростом нежелательной растительности
US6730668B2 (en) *	2001-09-20	2004-05-04	The Procter & Gamble Company	6,7-dihydro-5H-pyrazolo[1,2-a]pyrazol-1-ones which control inflammatory cytokines

2002
- 2002-09-18 US US10/245,927 patent/US6821971B2/en not_active Expired - Fee Related
- 2002-09-18 US US10/246,499 patent/US6566357B1/en not_active Expired - Fee Related
- 2002-09-20 KR KR10-2004-7004046A patent/KR20040035837A/ko not_active Application Discontinuation
- 2002-09-20 JP JP2003528817A patent/JP2005504081A/ja active Pending
- 2002-09-20 IL IL16068202A patent/IL160682A0/xx unknown
- 2002-09-20 WO PCT/US2002/030135 patent/WO2003024971A1/en active IP Right Grant
- 2002-09-20 CA CA002461071A patent/CA2461071A1/en not_active Abandoned
- 2002-09-20 PT PT02763692T patent/PT1427727E/pt unknown
- 2002-09-20 CA CA002461073A patent/CA2461073A1/en not_active Abandoned
- 2002-09-20 ES ES02763693T patent/ES2282459T3/es not_active Expired - Lifetime
- 2002-09-20 DE DE60202782T patent/DE60202782T2/de not_active Expired - Lifetime
- 2002-09-20 BR BR0212905-1A patent/BR0212905A/pt not_active IP Right Cessation
- 2002-09-20 DE DE60213108T patent/DE60213108T2/de not_active Expired - Fee Related
- 2002-09-20 MY MYPI20023518A patent/MY129329A/en unknown
- 2002-09-20 RU RU2004111803/04A patent/RU2299885C2/ru active
- 2002-09-20 NZ NZ531063A patent/NZ531063A/en not_active IP Right Cessation
- 2002-09-20 AR ARP020103548A patent/AR037145A1/es unknown
- 2002-09-20 ES ES02799017T patent/ES2268154T3/es not_active Expired - Lifetime
- 2002-09-20 IL IL16074202A patent/IL160742A0/xx unknown
- 2002-09-20 PL PL02370362A patent/PL370362A1/xx not_active Application Discontinuation
- 2002-09-20 EP EP02763693A patent/EP1427728B1/de not_active Expired - Lifetime
- 2002-09-20 SK SK148-2004A patent/SK1482004A3/sk unknown
- 2002-09-20 AT AT02763693T patent/ATE356126T1/de not_active IP Right Cessation
- 2002-09-20 SK SK150-2004A patent/SK1502004A3/sk unknown
- 2002-09-20 EP EP02799017A patent/EP1427732B1/de not_active Expired - Lifetime
- 2002-09-20 AU AU2002334641A patent/AU2002334641B2/en not_active Expired - Fee Related
- 2002-09-20 MX MXPA04002574A patent/MXPA04002574A/es active IP Right Grant
- 2002-09-20 DK DK02799017T patent/DK1427732T3/da active
- 2002-09-20 SK SK149-2004A patent/SK1492004A3/sk unknown
- 2002-09-20 PE PE2002000925A patent/PE20030474A1/es not_active Application Discontinuation
- 2002-09-20 WO PCT/US2002/030133 patent/WO2003024973A1/en not_active Application Discontinuation
- 2002-09-20 PL PL02370415A patent/PL370415A1/xx not_active Application Discontinuation
- 2002-09-20 PE PE2002000923A patent/PE20030430A1/es not_active Application Discontinuation
- 2002-09-20 ES ES02763692T patent/ES2237691T3/es not_active Expired - Lifetime
- 2002-09-20 EP EP02763692A patent/EP1427727B1/de not_active Expired - Lifetime
- 2002-09-20 HU HU0402500A patent/HUP0402500A3/hu unknown
- 2002-09-20 BR BR0212673-7A patent/BR0212673A/pt not_active IP Right Cessation
- 2002-09-20 RU RU2004111806/04A patent/RU2272040C2/ru not_active IP Right Cessation
- 2002-09-20 CN CNB028182286A patent/CN1257905C/zh not_active Expired - Fee Related
- 2002-09-20 IL IL16074102A patent/IL160741A0/xx unknown
- 2002-09-20 CA CA002461072A patent/CA2461072A1/en not_active Abandoned
- 2002-09-20 AU AU2002327690A patent/AU2002327690B2/en not_active Ceased
- 2002-09-20 AR ARP020103549A patent/AR037502A1/es not_active Application Discontinuation
- 2002-09-20 CZ CZ2004361A patent/CZ2004361A3/cs unknown
- 2002-09-20 HU HU0500752A patent/HUP0500752A2/hu unknown
- 2002-09-20 DE DE60218704T patent/DE60218704T2/de not_active Expired - Lifetime
- 2002-09-20 NZ NZ531122A patent/NZ531122A/en unknown
- 2002-09-20 PE PE2002000924A patent/PE20030446A1/es not_active Application Discontinuation
- 2002-09-20 MX MXPA04002569A patent/MXPA04002569A/es active IP Right Grant
- 2002-09-20 CN CNB028183800A patent/CN1249066C/zh not_active Expired - Fee Related
- 2002-09-20 CZ CZ2004345A patent/CZ2004345A3/cs unknown
- 2002-09-20 NZ NZ531123A patent/NZ531123A/en not_active IP Right Cessation
- 2002-09-20 DK DK02763693T patent/DK1427728T3/da active
- 2002-09-20 AR ARP020103550A patent/AR037237A1/es not_active Application Discontinuation
- 2002-09-20 PT PT02799017T patent/PT1427732E/pt unknown
- 2002-09-20 MY MYPI20023502A patent/MY129069A/en unknown
- 2002-09-20 PL PL02370351A patent/PL370351A1/xx not_active Application Discontinuation
- 2002-09-20 RU RU2004111805/04A patent/RU2278864C2/ru active
- 2002-09-20 HU HU0402378A patent/HUP0402378A3/hu unknown
- 2002-09-20 KR KR1020067006983A patent/KR20060036125A/ko not_active Application Discontinuation
- 2002-09-20 JP JP2003528818A patent/JP2005504082A/ja active Pending
- 2002-09-20 BR BR0212716-4A patent/BR0212716A/pt not_active IP Right Cessation
- 2002-09-20 MX MXPA04002570A patent/MXPA04002570A/es active IP Right Grant
- 2002-09-20 AT AT02799017T patent/ATE332901T1/de not_active IP Right Cessation
- 2002-09-20 AT AT02763692T patent/ATE287887T1/de not_active IP Right Cessation
- 2002-09-20 CN CNB028182294A patent/CN1250551C/zh not_active Expired - Fee Related
- 2002-09-20 CZ CZ2004358A patent/CZ2004358A3/cs unknown
- 2002-09-20 KR KR1020047004043A patent/KR100656126B1/ko not_active IP Right Cessation
- 2002-09-20 KR KR1020047004045A patent/KR100623879B1/ko not_active IP Right Cessation
- 2002-09-20 JP JP2003528820A patent/JP2005504083A/ja active Pending
- 2002-09-20 WO PCT/US2002/030134 patent/WO2003024970A1/en active IP Right Grant
- 2002-09-20 PT PT02763693T patent/PT1427728E/pt unknown
- 2002-09-21 EG EG2002091037A patent/EG24363A/xx active
- 2002-09-21 EG EG2002091039A patent/EG24413A/xx active
2003
- 2003-01-26 SA SA3230529A patent/SA03230529B1/ar unknown
2004
- 2004-02-17 ZA ZA200401260A patent/ZA200401260B/en unknown
- 2004-02-20 ZA ZA200401402A patent/ZA200401402B/en unknown
- 2004-02-20 ZA ZA200401403A patent/ZA200401403B/en unknown
- 2004-03-09 CO CO04021425A patent/CO5560590A2/es not_active Application Discontinuation
- 2004-03-09 CO CO04021424A patent/CO5560589A2/es not_active Application Discontinuation
- 2004-03-10 MA MA27567A patent/MA27064A1/fr unknown
- 2004-03-10 MA MA27568A patent/MA27065A1/fr unknown
- 2004-03-10 MA MA27569A patent/MA27066A1/fr unknown
- 2004-03-12 CO CO04023010A patent/CO5560579A2/es not_active Application Discontinuation
- 2004-04-19 NO NO20041594A patent/NO20041594L/no not_active Application Discontinuation
- 2004-04-20 NO NO20041605A patent/NO20041605L/no not_active Application Discontinuation
2005
- 2005-05-18 HK HK05104163A patent/HK1071366A1/xx not_active IP Right Cessation
- 2005-05-24 HK HK05104374A patent/HK1071565A1/xx not_active IP Right Cessation
2007
- 2007-03-20 CY CY20071100383T patent/CY1106398T1/el unknown

Also Published As

Publication number	Publication date
ES2282459T3 (es)	2007-10-16
IL160741A0 (en)	2004-08-31
PE20030430A1 (es)	2003-06-24
BR0212716A (pt)	2004-08-03
KR20040035836A (ko)	2004-04-29
EP1427728A1 (de)	2004-06-16
CN1250551C (zh)	2006-04-12
MXPA04002570A (es)	2004-05-31
JP2005504081A (ja)	2005-02-10
CA2461072A1 (en)	2003-03-27
EP1427727A1 (de)	2004-06-16
CO5560579A2 (es)	2005-09-30
US6821971B2 (en)	2004-11-23
DE60213108D1 (de)	2006-08-24
RU2272040C2 (ru)	2006-03-20
SA03230529B1 (ar)	2008-06-21
AU2002334641B2 (en)	2007-03-29
DE60202782T2 (de)	2006-01-19
WO2003024971A1 (en)	2003-03-27
WO2003024973A1 (en)	2003-03-27
ES2268154T3 (es)	2007-03-16
RU2004111805A (ru)	2005-04-10
EP1427728B1 (de)	2007-03-07
CN1249066C (zh)	2006-04-05
AR037237A1 (es)	2004-11-03
PT1427728E (pt)	2007-05-31
HUP0402500A2 (hu)	2005-03-29
CY1106398T1 (el)	2011-10-12
HUP0402500A3 (en)	2008-10-28
US20030105084A1 (en)	2003-06-05
HUP0500752A2 (en)	2006-01-30
KR100623879B1 (ko)	2006-09-19
US6566357B1 (en)	2003-05-20
PL370362A1 (en)	2005-05-16
AR037502A1 (es)	2004-11-17
DE60202782D1 (de)	2005-03-03
PE20030474A1 (es)	2003-07-22
KR20040035835A (ko)	2004-04-29
IL160742A0 (en)	2004-08-31
SK1502004A3 (en)	2004-09-08
BR0212673A (pt)	2004-08-24
JP2005504082A (ja)	2005-02-10
DK1427728T3 (da)	2007-07-09
ZA200401402B (en)	2004-08-27
ATE356126T1 (de)	2007-03-15
NO20041594L (no)	2004-06-21
PE20030446A1 (es)	2003-07-21
PL370415A1 (en)	2005-05-30
EP1427732B1 (de)	2006-07-12
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Date	Code	Title	Description
2008-03-27	8364	No opposition during term of opposition

Publication	Publication Date	Title
DE60218704D1 (de)	2007-04-19	6,7-DIHYDRO-5H-PYRAZOLOi1,2-Aö PYRAZOL-1-ONE ZUR KONTROLLE VON ENTZÜNDUNGSFÖRDERNDEN CYTOKINEN
DE60103351D1 (de)	2004-06-24	Zusammensetzung zur Bekämpfung von Ektoparasiten
FI20010694A0 (fi)	2001-04-03	Implantti
DE60126838D1 (de)	2007-04-05	Amidoacetonitrile zur Bekämpfung von Endoparasiten
NO20042474L (no)	2004-08-11	Reguleringsventil-stromningsjusteringsanordning.
NO20021472L (no)	2002-10-03	Intelligent brönn-sandkontroll
DE60210734D1 (de)	2006-05-24	Servoregler
DK1399355T3 (da)	2013-07-15	Styringsenhed
DE60202489D1 (de)	2005-02-03	Lysin enthaltende kautablette
DE60213426D1 (de)	2006-09-07	Abgasreinigungssystem
FI20011518A0 (fi)	2001-07-11	Liikeanalysaattori
DE50110880D1 (de)	2006-10-12	Gleitelementvorrichtung
DE60237780D1 (de)	2010-11-04	Motorsteuerung
DE60231432D1 (de)	2009-04-16	Steuersystem
DK1390364T3 (da)	2004-12-20	Aryl-8-azabicyclo[3.2.1]octaner til behandling af depression
DE60225366D1 (de)	2008-04-17	Expressionskontrollsequenz
NO20033189L (no)	2003-09-08	Kontrollmidler
DE60134712D1 (de)	2008-08-21	Regulierventil
FR2821760B1 (fr)	2003-06-20	Le cochonnet aimante
SE0102496L (sv)	2003-01-13	Utslagsramp
SE0100081L (sv)	2002-07-12	Utslagsramp
ES1049329Y (es)	2002-04-16	Ladrillo perfeccionado.
DK200100112U3 (da)	2001-07-13	Håndbetjening
SE0100908D0 (sv)	2001-03-14	Pulsaren - avloppssystem
FI20010181A (fi)	2002-08-01	Virtausohjain