DE602004003842D1 - Verfahren und automatisiertes Microfluidsystem zum Nachweis von Proteinen in biologischen Proben - Google Patents
Verfahren und automatisiertes Microfluidsystem zum Nachweis von Proteinen in biologischen ProbenInfo
- Publication number
- DE602004003842D1 DE602004003842D1 DE602004003842T DE602004003842T DE602004003842D1 DE 602004003842 D1 DE602004003842 D1 DE 602004003842D1 DE 602004003842 T DE602004003842 T DE 602004003842T DE 602004003842 T DE602004003842 T DE 602004003842T DE 602004003842 D1 DE602004003842 D1 DE 602004003842D1
- Authority
- DE
- Germany
- Prior art keywords
- proteins
- detection
- biological samples
- microfluidic system
- automated microfluidic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000012472 biological sample Substances 0.000 title 1
- 238000001514 detection method Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 102000004169 proteins and genes Human genes 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 title 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/02—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor using a plurality of sample containers moved by a conveyor system past one or more treatment or analysis stations
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/50—Containers for the purpose of retaining a material to be analysed, e.g. test tubes
- B01L3/502—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures
- B01L3/5027—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip
- B01L3/502723—Containers for the purpose of retaining a material to be analysed, e.g. test tubes with fluid transport, e.g. in multi-compartment structures by integrated microfluidic structures, i.e. dimensions of channels and chambers are such that surface tension forces are important, e.g. lab-on-a-chip characterised by venting arrangements
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2200/00—Solutions for specific problems relating to chemical or physical laboratory apparatus
- B01L2200/10—Integrating sample preparation and analysis in single entity, e.g. lab-on-a-chip concept
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2300/00—Additional constructional details
- B01L2300/08—Geometry, shape and general structure
- B01L2300/0861—Configuration of multiple channels and/or chambers in a single devices
- B01L2300/0867—Multiple inlets and one sample wells, e.g. mixing, dilution
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/04—Moving fluids with specific forces or mechanical means
- B01L2400/0475—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure
- B01L2400/0487—Moving fluids with specific forces or mechanical means specific mechanical means and fluid pressure fluid pressure, pneumatics
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L2400/00—Moving or stopping fluids
- B01L2400/06—Valves, specific forms thereof
- B01L2400/0622—Valves, specific forms thereof distribution valves, valves having multiple inlets and/or outlets, e.g. metering valves, multi-way valves
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Analytical Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Dispersion Chemistry (AREA)
- Hematology (AREA)
- Clinical Laboratory Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- General Physics & Mathematics (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Automatic Analysis And Handling Materials Therefor (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Investigating Or Analysing Biological Materials (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR2003003668 | 2003-01-20 | ||
KR10-2003-0003668A KR100537504B1 (ko) | 2003-01-20 | 2003-01-20 | 생물학적 시료 내에서의 단백질 검출을 위한 자동화된 유동 시스템 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE602004003842D1 true DE602004003842D1 (de) | 2007-02-08 |
DE602004003842T2 DE602004003842T2 (de) | 2007-04-12 |
Family
ID=36751403
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE602004003842T Expired - Lifetime DE602004003842T2 (de) | 2003-01-20 | 2004-01-20 | Verfahren und automatisiertes Microfluidsystem zum Nachweis von Proteinen in biologischen Proben |
Country Status (6)
Country | Link |
---|---|
US (1) | US6989130B2 (de) |
EP (1) | EP1441229B1 (de) |
JP (1) | JP3989446B2 (de) |
KR (1) | KR100537504B1 (de) |
CN (1) | CN1254686C (de) |
DE (1) | DE602004003842T2 (de) |
Families Citing this family (29)
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US7373255B2 (en) | 2003-06-06 | 2008-05-13 | Biacore Ab | Method and system for determination of molecular interaction parameters |
US20050191665A1 (en) * | 2003-12-29 | 2005-09-01 | Xing Su | Composite organic-inorganic nanoclusters |
US8168133B2 (en) | 2005-05-09 | 2012-05-01 | Wisconsin Alumni Research Foundation | Device for performing a high throughput assay |
US7410763B2 (en) * | 2005-09-01 | 2008-08-12 | Intel Corporation | Multiplex data collection and analysis in bioanalyte detection |
KR100749939B1 (ko) | 2006-08-09 | 2007-08-16 | 대한민국 | 검출항체 자동주입장치 |
WO2008063406A2 (en) * | 2006-11-08 | 2008-05-29 | Indermuhle Pierre Francois | A platform for binding assays with dual multiplexing capability |
CA2636409A1 (en) * | 2007-06-29 | 2008-12-29 | Matthew D. Briscoe | Apparatus for mobile collection of atmospheric sample for chemical analysis |
JP5173723B2 (ja) * | 2008-10-07 | 2013-04-03 | ローム株式会社 | マイクロチップ |
US20120048884A1 (en) * | 2009-04-27 | 2012-03-01 | Zhenfeng Wang | Apparatus and method for dispensing a liquid |
GB0913228D0 (en) | 2009-07-29 | 2009-09-02 | Iti Scotland Ltd | Loading element |
KR101034783B1 (ko) | 2009-09-24 | 2011-05-17 | 한국과학기술원 | 면역반응 검사장치용 반응부 및 이를 구비하는 다중 면역반응 검사장치 |
ITTO20100068U1 (it) * | 2010-04-20 | 2011-10-21 | Eltek Spa | Dispositivi microfluidici e/o attrezzature per dispositivi microfluidici |
US8596340B1 (en) | 2010-10-13 | 2013-12-03 | Horn-Barber Technologies, LLC | Apparatus for heating liquid samples for analysis |
KR101821410B1 (ko) * | 2011-01-10 | 2018-01-23 | 엘지전자 주식회사 | 마이크로 유체 디바이스 및 그의 제어 방법과 버블 제어 방법 |
KR101356628B1 (ko) | 2011-11-30 | 2014-02-04 | 한국과학기술원 | 다중 바이오마커 동시 면역반응검사 방법 및 장치 |
FI124909B (fi) * | 2012-02-03 | 2015-03-13 | Timo Kalevi Korpela | Mekaaninen pesu- ja mittauslaite ja menetelmä analyysin suorittamiseksi |
CN103439484B (zh) * | 2013-08-13 | 2015-12-23 | 武汉血液中心 | 一种显色质控物及其应用 |
US10082500B2 (en) | 2013-08-22 | 2018-09-25 | Franz Baudenbacher | Device and method for detecting a target analyte |
US9956557B2 (en) | 2015-07-24 | 2018-05-01 | HJ Science & Technology, Inc. | Reconfigurable microfluidic systems: microwell plate interface |
US9733239B2 (en) | 2015-07-24 | 2017-08-15 | HJ Science & Technology, Inc. | Reconfigurable microfluidic systems: scalable, multiplexed immunoassays |
US9956558B2 (en) | 2015-07-24 | 2018-05-01 | HJ Science & Technology, Inc. | Reconfigurable microfluidic systems: homogeneous assays |
BR112019007121A2 (pt) * | 2016-10-07 | 2019-07-02 | Boehringer Ingelheim Vetmedica Gmbh | cartucho, sistema de análise e método para testagem de uma amostra |
KR101863315B1 (ko) * | 2017-02-24 | 2018-06-29 | 계명대학교 산학협력단 | 자동 주입형 진단 키트 장비 |
KR101992861B1 (ko) * | 2017-10-12 | 2019-06-27 | 한국과학기술원 | 미세유로 제어시스템 및 이의 제어방법 |
KR102425126B1 (ko) * | 2018-02-12 | 2022-07-29 | 한국전자통신연구원 | 바이오 반응 유체 제어장치, 바이오 반응 시스템 및 바이오 반응 유체 제어방법 |
TWI675106B (zh) * | 2018-03-21 | 2019-10-21 | 緯創資通股份有限公司 | 液體處理模組、液體檢測系統及利用液體處理模組進行檢測的檢測方法 |
EP3787795A4 (de) | 2018-04-30 | 2022-01-26 | Protein Fluidics, Inc. | Ventilloser fluidischer schalt-flowchip und verwendungen davon |
KR20220002735A (ko) * | 2019-05-28 | 2022-01-06 | 일루미나, 인코포레이티드 | 2-상 플러싱 시스템 및 방법 |
RU200301U1 (ru) * | 2019-05-31 | 2020-10-15 | Общество с ограниченной ответственностью "ИНФРАКАП-МЕДИЦИНА" | Микрофлюидный чип для проведения многопараметрического иммуноанализа |
Family Cites Families (22)
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US4381099A (en) * | 1981-04-28 | 1983-04-26 | The Penmont Company | Faucet for frozen carbonated beverage machine |
US4598628A (en) * | 1984-05-21 | 1986-07-08 | 4 Square Motors | Rotary hydraulic engine having oppositely disposed pistons in a scotch yoke assembly |
US4895706A (en) * | 1986-10-28 | 1990-01-23 | Costar Corporation | Multi-well filter strip and composite assemblies |
US5219529A (en) * | 1987-07-07 | 1993-06-15 | Unisyn Technologies, Inc. | Cartridge assembly |
US5321123A (en) * | 1991-07-02 | 1994-06-14 | The Scripps Research Institute | Protein S polypeptides and anti-peptide antibodies that inhibit protein S binding to C4B binding protein, diagnostic systems and therapeutic methods |
CA2156174A1 (en) * | 1993-02-17 | 1994-09-01 | Bruce Oberhardt | Dry chemistry cascade immunoassay and affinity assay |
AU7043594A (en) * | 1993-05-28 | 1994-12-20 | Ensys Environmental Products, Inc. | A polychlorinated biphenyls (pcb) immunoassay method, its components and a kit for use in performing the same |
US5472672A (en) * | 1993-10-22 | 1995-12-05 | The Board Of Trustees Of The Leland Stanford Junior University | Apparatus and method for polymer synthesis using arrays |
US5603351A (en) * | 1995-06-07 | 1997-02-18 | David Sarnoff Research Center, Inc. | Method and system for inhibiting cross-contamination in fluids of combinatorial chemistry device |
US5697132A (en) * | 1996-06-17 | 1997-12-16 | Morganthal Llc | System and method for automated mixing and delivery of embalming fluid to a cadaver |
EP2295988A2 (de) * | 1996-12-31 | 2011-03-16 | High Throughput Genomics, Inc. | Multiplex-Analysevorrichtung zur Analyse von Molekülen und zugehöriges Herstellungsverfahren |
US6146595A (en) * | 1998-02-10 | 2000-11-14 | Balazs Analytical Laboratory | Closed evaporator system for preparing samples for analysis |
US6117396A (en) * | 1998-02-18 | 2000-09-12 | Orchid Biocomputer, Inc. | Device for delivering defined volumes |
US6033911A (en) * | 1998-02-27 | 2000-03-07 | Hamilton Company | Automated assaying device |
US6093869A (en) * | 1998-06-29 | 2000-07-25 | The Procter & Gamble Company | Disposable article having a responsive system including a feedback control loop |
US6485690B1 (en) * | 1999-05-27 | 2002-11-26 | Orchid Biosciences, Inc. | Multiple fluid sample processor and system |
WO2000078456A1 (en) * | 1999-06-19 | 2000-12-28 | Orchid Biosciences, Inc. | Microfluidic device interface |
US6395232B1 (en) * | 1999-07-09 | 2002-05-28 | Orchid Biosciences, Inc. | Fluid delivery system for a microfluidic device using a pressure pulse |
DE60013848T2 (de) | 1999-08-12 | 2005-09-22 | UT-Battelle, LLC., Oak Ridge | Mikrofluid-vorrichtungen zur gesteuerten handhabung von kleinstvolumen |
CN1425133A (zh) | 1999-10-13 | 2003-06-18 | 西格雷特生物科学有限公司 | 检测和识别试样中分子事件的***和方法 |
WO2001062377A2 (en) | 2000-02-22 | 2001-08-30 | Genospectra, Inc. | Microarray fabrication techniques and apparatus |
US6729352B2 (en) * | 2001-06-07 | 2004-05-04 | Nanostream, Inc. | Microfluidic synthesis devices and methods |
-
2003
- 2003-01-20 KR KR10-2003-0003668A patent/KR100537504B1/ko not_active IP Right Cessation
-
2004
- 2004-01-19 JP JP2004010366A patent/JP3989446B2/ja not_active Expired - Fee Related
- 2004-01-20 EP EP04001087A patent/EP1441229B1/de not_active Expired - Fee Related
- 2004-01-20 CN CNB2004100059092A patent/CN1254686C/zh not_active Expired - Fee Related
- 2004-01-20 DE DE602004003842T patent/DE602004003842T2/de not_active Expired - Lifetime
- 2004-01-20 US US10/761,846 patent/US6989130B2/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
US6989130B2 (en) | 2006-01-24 |
JP3989446B2 (ja) | 2007-10-10 |
CN1517712A (zh) | 2004-08-04 |
KR100537504B1 (ko) | 2005-12-19 |
EP1441229A1 (de) | 2004-07-28 |
US20040152200A1 (en) | 2004-08-05 |
JP2004226403A (ja) | 2004-08-12 |
EP1441229B1 (de) | 2006-12-27 |
KR20040066564A (ko) | 2004-07-27 |
CN1254686C (zh) | 2006-05-03 |
DE602004003842T2 (de) | 2007-04-12 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |