DE60144142D1 - Mikromechanische geräte und verfahren zur speicherung und zur selektiven exposition von chemikalien - Google Patents
Mikromechanische geräte und verfahren zur speicherung und zur selektiven exposition von chemikalienInfo
- Publication number
- DE60144142D1 DE60144142D1 DE60144142T DE60144142T DE60144142D1 DE 60144142 D1 DE60144142 D1 DE 60144142D1 DE 60144142 T DE60144142 T DE 60144142T DE 60144142 T DE60144142 T DE 60144142T DE 60144142 D1 DE60144142 D1 DE 60144142D1
- Authority
- DE
- Germany
- Prior art keywords
- sensor
- reservoir
- reservoir cap
- environmental component
- chemicals
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T29/00—Metal working
- Y10T29/49—Method of mechanical manufacture
- Y10T29/49002—Electrical device making
- Y10T29/49117—Conductor or circuit manufacturing
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
- Y10T436/00—Chemistry: analytical and immunological testing
- Y10T436/25—Chemistry: analytical and immunological testing including sample preparation
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US18654500P | 2000-03-02 | 2000-03-02 | |
PCT/US2001/006886 WO2001064344A2 (en) | 2000-03-02 | 2001-03-02 | Microfabricated devices for the storage and selective exposure of chemicals and devices |
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DE60144142D1 true DE60144142D1 (de) | 2011-04-14 |
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DE60144142T Expired - Lifetime DE60144142D1 (de) | 2000-03-02 | 2001-03-02 | Mikromechanische geräte und verfahren zur speicherung und zur selektiven exposition von chemikalien |
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US (9) | US6551838B2 (de) |
EP (1) | EP1261427B1 (de) |
JP (2) | JP3960802B2 (de) |
AT (1) | ATE499988T1 (de) |
AU (3) | AU2001252890B2 (de) |
CA (1) | CA2399842C (de) |
DE (1) | DE60144142D1 (de) |
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Families Citing this family (413)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6783543B2 (en) * | 2000-06-05 | 2004-08-31 | Scimed Life Systems, Inc. | Intravascular stent with increasing coating retaining capacity |
US7070590B1 (en) * | 1996-07-02 | 2006-07-04 | Massachusetts Institute Of Technology | Microchip drug delivery devices |
US7341598B2 (en) | 1999-01-13 | 2008-03-11 | Boston Scientific Scimed, Inc. | Stent with protruding branch portion for bifurcated vessels |
US8527026B2 (en) | 1997-03-04 | 2013-09-03 | Dexcom, Inc. | Device and method for determining analyte levels |
US6001067A (en) | 1997-03-04 | 1999-12-14 | Shults; Mark C. | Device and method for determining analyte levels |
US20040254635A1 (en) * | 1998-03-30 | 2004-12-16 | Shanley John F. | Expandable medical device for delivery of beneficial agent |
US7179289B2 (en) * | 1998-03-30 | 2007-02-20 | Conor Medsystems, Inc. | Expandable medical device for delivery of beneficial agent |
US6241762B1 (en) | 1998-03-30 | 2001-06-05 | Conor Medsystems, Inc. | Expandable medical device with ductile hinges |
US7208011B2 (en) * | 2001-08-20 | 2007-04-24 | Conor Medsystems, Inc. | Implantable medical device with drug filled holes |
US7208010B2 (en) * | 2000-10-16 | 2007-04-24 | Conor Medsystems, Inc. | Expandable medical device for delivery of beneficial agent |
WO2000040089A1 (en) * | 1999-01-05 | 2000-07-13 | Massachusetts Eye And Ear Infirmary | Targeted transscleral controlled release drug delivery to the retina and choroid |
EP1210064B1 (de) * | 1999-08-18 | 2005-03-09 | Microchips, Inc. | Thermisch aktivierbarer microchip als abgabevorrichtung für chemikalien |
JP2003516343A (ja) * | 1999-12-10 | 2003-05-13 | マサチューセッツ インスティテュート オブ テクノロジー | 分子を送達するマイクロチップ素子およびその製作方法 |
EP1261427B1 (de) * | 2000-03-02 | 2011-03-02 | Microchips, Inc. | Mikromechanische geräte und verfahren zur speicherung und zur selektiven exposition von chemikalien |
EP1132058A1 (de) * | 2000-03-06 | 2001-09-12 | Advanced Laser Applications Holding S.A. | Intravaskuläre Prothese |
WO2001073883A2 (en) | 2000-03-24 | 2001-10-04 | Cymbet Corporation | Low-temperature fabrication of thin-film energy-storage devices |
EP1296615B2 (de) * | 2000-06-05 | 2012-06-13 | Boston Scientific Limited | INTRAVASKULÄRER STENT MIT verbessertem Haltevermögen einer Beschichtung |
DE60116520T2 (de) * | 2000-10-10 | 2006-08-31 | Microchips, Inc., Bedford | Microchip-reservoir-vorrichtungen mit drahtloser übertragung von energie und daten |
WO2002030401A2 (en) | 2000-10-11 | 2002-04-18 | Microchips, Inc. | Microchip reservoir devices and facilitated corrosion of electrodes |
DE60112318D1 (de) | 2000-10-16 | 2005-09-01 | Conor Medsystems Inc | Expandierbare medizinische vorrichtung zum zuführen eines heilmittels |
DE60139705D1 (de) * | 2000-11-09 | 2009-10-08 | Sicel Technologies Inc | In-vivo detektion von biomolekülekonzentrationen mittels fluoreszenzmarker |
US9107605B2 (en) * | 2000-11-17 | 2015-08-18 | Advanced Bio Prosthetic Surfaces, Ltd., A Wholly Owned Subsidiary Of Palmaz Scientific, Inc. | Device for in vivo delivery of bioactive agents and method of manufacture thereof |
JP4657577B2 (ja) | 2001-01-09 | 2011-03-23 | マイクロチップス・インコーポレーテッド | 眼への適用および他への適用のための可撓性マイクロチップデバイス |
US20040073294A1 (en) * | 2002-09-20 | 2004-04-15 | Conor Medsystems, Inc. | Method and apparatus for loading a beneficial agent into an expandable medical device |
US20040220660A1 (en) * | 2001-02-05 | 2004-11-04 | Shanley John F. | Bioresorbable stent with beneficial agent reservoirs |
US6858220B2 (en) | 2001-02-28 | 2005-02-22 | Second Sight Medical Products, Inc. | Implantable microfluidic delivery system using ultra-nanocrystalline diamond coating |
US20040058407A1 (en) * | 2001-04-10 | 2004-03-25 | Miller Scott E. | Reactor systems having a light-interacting component |
US20050032204A1 (en) * | 2001-04-10 | 2005-02-10 | Bioprocessors Corp. | Microreactor architecture and methods |
US20040132166A1 (en) * | 2001-04-10 | 2004-07-08 | Bioprocessors Corp. | Determination and/or control of reactor environmental conditions |
US20040058437A1 (en) * | 2001-04-10 | 2004-03-25 | Rodgers Seth T. | Materials and reactor systems having humidity and gas control |
WO2002096389A1 (en) | 2001-05-30 | 2002-12-05 | Microchips, Inc. | Conformal coated microchip reservoir devices |
WO2002099457A1 (en) * | 2001-05-31 | 2002-12-12 | Massachusetts Inst Technology | Microchip devices with improved reservoir opening |
CA2451953A1 (en) * | 2001-06-28 | 2003-04-24 | Microchips, Inc. | Methods for hermetically sealing microchip reservoir devices |
DE10133870A1 (de) * | 2001-07-12 | 2003-02-06 | Chris P Lohmann | Ophthalmisches Mittel, Verwendung von EGF zur Behandlung von Dry Eye-Syndrom und Insert zur Verabreichung von EGF am Auge |
US20030032874A1 (en) | 2001-07-27 | 2003-02-13 | Dexcom, Inc. | Sensor head for use with implantable devices |
US7842083B2 (en) | 2001-08-20 | 2010-11-30 | Innovational Holdings, Llc. | Expandable medical device with improved spatial distribution |
US7056338B2 (en) * | 2003-03-28 | 2006-06-06 | Conor Medsystems, Inc. | Therapeutic agent delivery device with controlled therapeutic agent release rates |
DE10142019A1 (de) * | 2001-08-28 | 2003-03-20 | Philips Corp Intellectual Pty | Schaltungsanordnung zur Demodulation von Signalen |
US7578841B2 (en) | 2001-09-24 | 2009-08-25 | Boston Scientific Scimed, Inc. | Stent with protruding branch portion for bifurcated vessels |
JP4220386B2 (ja) * | 2001-10-09 | 2009-02-04 | エナジー リレーテッド デバイシーズ インク | 膜を使用する触媒ヒーター |
US7097775B2 (en) * | 2001-10-26 | 2006-08-29 | Second Sight Medical Products, Inc. | Coated microfluidic delivery system |
WO2003051286A2 (en) * | 2001-11-01 | 2003-06-26 | Regents Of The University Of Minnesota | Hydrogel compositions, devices, and microscale components |
US7354597B2 (en) | 2001-12-03 | 2008-04-08 | Massachusetts Institute Of Technology | Microscale lyophilization and drying methods for the stabilization of molecules |
US20050154272A1 (en) * | 2002-01-23 | 2005-07-14 | Danfoss A/S | Method and device for monitoring analyte concentration by use of differential osmotic pressure measurement |
US8364229B2 (en) | 2003-07-25 | 2013-01-29 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
US7613491B2 (en) | 2002-05-22 | 2009-11-03 | Dexcom, Inc. | Silicone based membranes for use in implantable glucose sensors |
GB0204381D0 (en) * | 2002-02-26 | 2002-04-10 | Mcminn Derek J W | Knee prosthesis |
AU2003217531A1 (en) * | 2002-05-02 | 2003-11-17 | Massachusetts Eye And Ear Infirmary | Ocular drug delivery systems and use thereof |
US7226978B2 (en) | 2002-05-22 | 2007-06-05 | Dexcom, Inc. | Techniques to improve polyurethane membranes for implantable glucose sensors |
US20050106714A1 (en) * | 2002-06-05 | 2005-05-19 | Zarur Andrey J. | Rotatable reactor systems and methods |
US6953455B2 (en) * | 2002-07-30 | 2005-10-11 | Hospira, Inc. | Medicine delivery system |
JP2004080221A (ja) * | 2002-08-13 | 2004-03-11 | Fujitsu Media Device Kk | 弾性波デバイス及びその製造方法 |
EP1528940B1 (de) * | 2002-08-16 | 2011-04-13 | Microchips, Inc. | Vorrichtung mit kontrollierter abgabe und verfahren |
AU2007200736B2 (en) * | 2002-08-16 | 2008-09-18 | Microchips, Inc. | Controlled release device and method |
US7287412B2 (en) * | 2003-06-03 | 2007-10-30 | Nano-Proprietary, Inc. | Method and apparatus for sensing hydrogen gas |
US7497855B2 (en) * | 2002-09-04 | 2009-03-03 | Microchips, Inc. | Method and device for the controlled delivery of parathyroid hormone |
EP1539043B1 (de) * | 2002-09-20 | 2013-12-18 | Innovational Holdings, LLC | Expandierbare medizinische vorrichtung mit öffnungen zur abgabe multipler heilmittel |
US7758636B2 (en) * | 2002-09-20 | 2010-07-20 | Innovational Holdings Llc | Expandable medical device with openings for delivery of multiple beneficial agents |
AU2012203970B2 (en) * | 2002-09-20 | 2015-08-20 | MicroPort Cardiovascular LLC | Method and apparatus for loading a beneficial agent into an expandable medical device |
AU2003278881A1 (en) * | 2002-09-23 | 2004-04-08 | Microchips, Inc. | Micro-reservoir osmotic release systems and microtube array device |
EP1551499A1 (de) * | 2002-10-04 | 2005-07-13 | Microchips, Inc. | Medizinische vorrichtung zur nervenstimulation und kontrollierten verabreichung von medikamenten |
EP1551505B1 (de) * | 2002-10-04 | 2010-02-24 | Microchips, Inc. | Medizinische vorrichtung zur gesteuerten arzneimittelverabreichung sowie herzüberwachung und/oder herzstimulation |
WO2004034028A2 (en) * | 2002-10-09 | 2004-04-22 | The Board Of Trustees Of The University Of Illinois | Microfluidic systems and components |
US20040072334A1 (en) * | 2002-10-15 | 2004-04-15 | The Regents Of The University Of California | Thermal cycler |
US20090209030A1 (en) * | 2002-10-15 | 2009-08-20 | Benett William J | Thermal Cycler |
US9740817B1 (en) | 2002-10-18 | 2017-08-22 | Dennis Sunga Fernandez | Apparatus for biological sensing and alerting of pharmaco-genomic mutation |
EP1419818B1 (de) * | 2002-11-14 | 2013-10-30 | Boehringer Ingelheim microParts GmbH | Vorrichtung zum schrittweisen Transport von Flüssigkeit unter Ausnutzung von Kapillarkräften |
US7294209B2 (en) * | 2003-01-02 | 2007-11-13 | Cymbet Corporation | Apparatus and method for depositing material onto a substrate using a roll-to-roll mask |
US20040131760A1 (en) * | 2003-01-02 | 2004-07-08 | Stuart Shakespeare | Apparatus and method for depositing material onto multiple independently moving substrates in a chamber |
US7603144B2 (en) * | 2003-01-02 | 2009-10-13 | Cymbet Corporation | Active wireless tagging system on peel and stick substrate |
US6906436B2 (en) * | 2003-01-02 | 2005-06-14 | Cymbet Corporation | Solid state activity-activated battery device and method |
WO2004073551A2 (en) * | 2003-02-18 | 2004-09-02 | Massachusetts Eye And Ear Infirmary | Transscleral drug delivery device and related methods |
WO2004084973A2 (en) * | 2003-03-24 | 2004-10-07 | Becton, Dickinson And Company | Invisible antimicrobial glove and hand antiseptic |
EP2272544A1 (de) | 2003-03-28 | 2011-01-12 | Conor Medsystems, Inc. | Implantierbare medizinische Vorrichtung enthaltend eine therapeutische Substanz in einem Konzentrationsgradient. |
US20040202692A1 (en) * | 2003-03-28 | 2004-10-14 | Conor Medsystems, Inc. | Implantable medical device and method for in situ selective modulation of agent delivery |
ATE494885T1 (de) * | 2003-04-25 | 2011-01-15 | Boston Scient Scimed Inc | Feste arzneimittelformulierung und vorrichtung zu ihrer aufbewahrung und kontrollierten abgabe |
JP3892826B2 (ja) * | 2003-05-26 | 2007-03-14 | 株式会社東芝 | 電力増幅器及びこれを用いた無線通信装置 |
US7169179B2 (en) * | 2003-06-05 | 2007-01-30 | Conor Medsystems, Inc. | Drug delivery device and method for bi-directional drug delivery |
WO2004112946A2 (en) * | 2003-06-05 | 2004-12-29 | Bioprocessors Corp. | Reactor with memory component |
US7226441B2 (en) * | 2003-06-23 | 2007-06-05 | Codman & Shurtleff, Inc. | Catheter with block-overriding system |
WO2005010240A2 (en) * | 2003-07-17 | 2005-02-03 | Microchips, Inc. | Low temperature methods for hermetically sealing reservoir devices |
US9763609B2 (en) | 2003-07-25 | 2017-09-19 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
WO2005011520A2 (en) | 2003-07-25 | 2005-02-10 | Dexcom, Inc. | Oxygen enhancing membrane systems for implantable devices |
WO2005012873A2 (en) | 2003-07-25 | 2005-02-10 | Dexcom, Inc. | Electrode systems for electrochemical sensors |
WO2007120442A2 (en) | 2003-07-25 | 2007-10-25 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
WO2005016558A2 (en) * | 2003-08-04 | 2005-02-24 | Microchips, Inc. | Methods for accelerated release of material from a reservoir device |
US7169405B2 (en) * | 2003-08-06 | 2007-01-30 | Warsaw Orthopedic, Inc. | Methods and devices for the treatment of intervertebral discs |
US8346482B2 (en) | 2003-08-22 | 2013-01-01 | Fernandez Dennis S | Integrated biosensor and simulation system for diagnosis and therapy |
US7920906B2 (en) | 2005-03-10 | 2011-04-05 | Dexcom, Inc. | System and methods for processing analyte sensor data for sensor calibration |
CN1905835B (zh) * | 2003-09-11 | 2011-11-30 | 赛拉诺斯股份有限公司 | 分析物监测和药物递送的医疗装置 |
AU2012213965B2 (en) * | 2003-09-11 | 2015-10-22 | Labrador Diagnostics Llc | Medical device for analyte monitoring and drug delivery |
US7785653B2 (en) * | 2003-09-22 | 2010-08-31 | Innovational Holdings Llc | Method and apparatus for loading a beneficial agent into an expandable medical device |
US7723208B2 (en) * | 2003-09-24 | 2010-05-25 | Intel Corporation | Integrated re-combiner for electroosmotic pumps using porous frits |
US7211351B2 (en) * | 2003-10-16 | 2007-05-01 | Cymbet Corporation | Lithium/air batteries with LiPON as separator and protective barrier and method |
AU2004285603A1 (en) * | 2003-11-03 | 2005-05-12 | Microchips, Inc. | Medical device for sensing glucose |
ATE476909T1 (de) * | 2003-11-13 | 2010-08-15 | Medtronic Minimed Inc | Langzeit-analytensensor-anordnung |
US8414489B2 (en) * | 2003-11-13 | 2013-04-09 | Medtronic Minimed, Inc. | Fabrication of multi-sensor arrays |
US9247900B2 (en) | 2004-07-13 | 2016-02-02 | Dexcom, Inc. | Analyte sensor |
ATE480761T1 (de) | 2003-12-05 | 2010-09-15 | Dexcom Inc | Kalibrationsmethoden für einen kontinuierlich arbeitenden analytsensor |
US8423114B2 (en) | 2006-10-04 | 2013-04-16 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
US11633133B2 (en) | 2003-12-05 | 2023-04-25 | Dexcom, Inc. | Dual electrode system for a continuous analyte sensor |
US7494742B2 (en) * | 2004-01-06 | 2009-02-24 | Cymbet Corporation | Layered barrier structure having one or more definable layers and method |
WO2005079387A2 (en) * | 2004-02-13 | 2005-09-01 | Conor Medsystems, Inc. | Implantable drug delivery device including wire filaments |
US7819822B2 (en) * | 2004-03-06 | 2010-10-26 | Roche Diagnostics Operations, Inc. | Body fluid sampling device |
ES2541680T3 (es) * | 2004-03-06 | 2015-07-23 | F. Hoffmann-La Roche Ag | Dispositivo de muestreo de líquidos corporales |
US7215018B2 (en) | 2004-04-13 | 2007-05-08 | Vertical Circuits, Inc. | Stacked die BGA or LGA component assembly |
US7705432B2 (en) * | 2004-04-13 | 2010-04-27 | Vertical Circuits, Inc. | Three dimensional six surface conformal die coating |
US7245021B2 (en) | 2004-04-13 | 2007-07-17 | Vertical Circuits, Inc. | Micropede stacked die component assembly |
US8277713B2 (en) | 2004-05-03 | 2012-10-02 | Dexcom, Inc. | Implantable analyte sensor |
US7060895B2 (en) * | 2004-05-04 | 2006-06-13 | Idc, Llc | Modifying the electro-mechanical behavior of devices |
US20050261561A1 (en) * | 2004-05-24 | 2005-11-24 | Christopher W. Jones | Blood testing and therapeutic compound delivery system |
AU2005327211A1 (en) * | 2004-06-01 | 2006-08-17 | Microchips, Inc. | Devices and methods for measuring and enhancing drug or analyte transport to/from medical implant |
US20050271560A1 (en) * | 2004-06-07 | 2005-12-08 | Bioprocessors Corp. | Gas control in a reactor |
EP1758674A2 (de) * | 2004-06-07 | 2007-03-07 | Bioprocessors Corporation | Schuberzeugung in einem reaktor |
US20050287673A1 (en) * | 2004-06-07 | 2005-12-29 | Bioprocessors Corp. | Reactor mixing |
WO2005120698A2 (en) * | 2004-06-07 | 2005-12-22 | Bioprocessors Corp. | Control of reactor environmental conditions |
US20050287287A1 (en) * | 2004-06-24 | 2005-12-29 | Parker Theodore L | Methods and systems for loading an implantable medical device with beneficial agent |
US8536661B1 (en) | 2004-06-25 | 2013-09-17 | University Of Hawaii | Biosensor chip sensor protection methods |
US7946984B2 (en) | 2004-07-13 | 2011-05-24 | Dexcom, Inc. | Transcutaneous analyte sensor |
WO2006127694A2 (en) | 2004-07-13 | 2006-11-30 | Dexcom, Inc. | Analyte sensor |
US20070036835A1 (en) * | 2004-07-19 | 2007-02-15 | Microchips, Inc. | Hermetically Sealed Devices for Controlled Release or Exposure of Reservoir Contents |
US7537590B2 (en) * | 2004-07-30 | 2009-05-26 | Microchips, Inc. | Multi-reservoir device for transdermal drug delivery and sensing |
CN100488635C (zh) * | 2004-09-01 | 2009-05-20 | 微芯片公司 | 用于控制释放或者暴露储库内容物的多盖储库装置 |
US7550912B2 (en) | 2004-09-27 | 2009-06-23 | Idc, Llc | Method and system for maintaining partial vacuum in display device |
CA2583911A1 (en) * | 2004-10-28 | 2006-05-11 | Microchips, Inc. | Orthopedic and dental implant devices providing controlled drug delivery |
CA2584851C (en) * | 2004-11-04 | 2015-04-07 | Microchips, Inc. | Compression and cold weld sealing methods and devices |
US7413846B2 (en) * | 2004-11-15 | 2008-08-19 | Microchips, Inc. | Fabrication methods and structures for micro-reservoir devices |
US20080009800A1 (en) * | 2004-12-02 | 2008-01-10 | Nickel Janice H | Transdermal drug delivery device |
DE102004058394A1 (de) * | 2004-12-03 | 2006-06-14 | Fraunhofer-Gesellschaft zur Förderung der angewandten Forschung e.V. | Probenaufnahme für eine Kryoprobe und zugehöriges Untersuchungsverfahren |
US20090306633A1 (en) * | 2005-01-18 | 2009-12-10 | Koninklijke Philips Electronics, N.V. | Electronically controlled capsule |
WO2006081279A2 (en) * | 2005-01-25 | 2006-08-03 | Microchips, Inc. | Control of drug release by transient modification of local microenvironments |
US7584907B2 (en) | 2005-03-29 | 2009-09-08 | Contadini Carl D | Precision release aerosol device |
US20100001104A1 (en) * | 2005-03-29 | 2010-01-07 | Waterbury Companies, Inc. | Precision release vaporization device |
US20060226442A1 (en) * | 2005-04-07 | 2006-10-12 | An-Ping Zhang | GaN-based high electron mobility transistor and method for making the same |
US8744546B2 (en) | 2005-05-05 | 2014-06-03 | Dexcom, Inc. | Cellulosic-based resistance domain for an analyte sensor |
US9284375B2 (en) * | 2005-04-15 | 2016-03-15 | Macrogenics, Inc. | Covalent diabodies and uses thereof |
US20060264779A1 (en) | 2005-05-09 | 2006-11-23 | Kemp Timothy M | Fluidic medical devices and uses thereof |
US7629115B2 (en) | 2005-05-13 | 2009-12-08 | Honeywell International Inc. | Cell-based platform for high throughput screening |
US8309057B2 (en) * | 2005-06-10 | 2012-11-13 | The Invention Science Fund I, Llc | Methods for elevating neurotrophic agents |
EP1733676B1 (de) * | 2005-06-17 | 2012-08-01 | F. Hoffmann-La Roche AG | Sensorsystem sowie Anordnung und Verfahren zur Überwachung eines Inhaltsstoffs, insbesondere Glucose in Körpergewebe |
WO2007001624A2 (en) * | 2005-06-28 | 2007-01-04 | Microchips, Inc. | Medical and dental implant devices for controlled drug delivery |
WO2007004171A1 (en) * | 2005-07-05 | 2007-01-11 | Koninklijke Philips Electronics N.V. | Device for the controlled release of a predefined quantity of a substance |
US7776478B2 (en) * | 2005-07-15 | 2010-08-17 | Cymbet Corporation | Thin-film batteries with polymer and LiPON electrolyte layers and method |
US7931989B2 (en) | 2005-07-15 | 2011-04-26 | Cymbet Corporation | Thin-film batteries with soft and hard electrolyte layers and method |
US20070012244A1 (en) * | 2005-07-15 | 2007-01-18 | Cymbet Corporation | Apparatus and method for making thin-film batteries with soft and hard electrolyte layers |
US20080228044A1 (en) * | 2005-10-11 | 2008-09-18 | Koninklijke Philips Electronics, N.V. | Individually Activated Sensors for Implantable Sensors |
US20070088442A1 (en) * | 2005-10-14 | 2007-04-19 | Microchips, Inc. | Passive wear-indicating sensor for implantable prosthetic device |
US8273071B2 (en) | 2006-01-18 | 2012-09-25 | The Invention Science Fund I, Llc | Remote controller for substance delivery system |
US8882747B2 (en) * | 2005-11-09 | 2014-11-11 | The Invention Science Fund I, Llc | Substance delivery system |
US9067047B2 (en) | 2005-11-09 | 2015-06-30 | The Invention Science Fund I, Llc | Injectable controlled release fluid delivery system |
US20070106277A1 (en) * | 2005-11-09 | 2007-05-10 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Remote controller for substance delivery system |
US9254256B2 (en) * | 2005-11-09 | 2016-02-09 | The Invention Science Fund I, Llc | Remote controlled in vivo reaction method |
US8998886B2 (en) * | 2005-12-13 | 2015-04-07 | The Invention Science Fund I, Llc | Remote control of osmotic pump device |
US8992511B2 (en) | 2005-11-09 | 2015-03-31 | The Invention Science Fund I, Llc | Acoustically controlled substance delivery device |
US8936590B2 (en) | 2005-11-09 | 2015-01-20 | The Invention Science Fund I, Llc | Acoustically controlled reaction device |
US8083710B2 (en) * | 2006-03-09 | 2011-12-27 | The Invention Science Fund I, Llc | Acoustically controlled substance delivery device |
US20070129620A1 (en) * | 2005-12-02 | 2007-06-07 | Peter Krulevitch | Selectively exposable miniature probes with integrated sensor arrays for continuous in vivo diagnostics |
US7540881B2 (en) | 2005-12-22 | 2009-06-02 | Boston Scientific Scimed, Inc. | Bifurcation stent pattern |
US8095198B2 (en) | 2006-01-31 | 2012-01-10 | Warsaw Orthopedic. Inc. | Methods for detecting osteolytic conditions in the body |
US8078282B2 (en) | 2006-02-01 | 2011-12-13 | Warsaw Orthopedic, Inc | Implantable tissue growth stimulator |
US7328131B2 (en) * | 2006-02-01 | 2008-02-05 | Medtronic, Inc. | Implantable pedometer |
US20070191816A1 (en) * | 2006-02-13 | 2007-08-16 | Boston Scientific Scimed, Inc. | Radio frequency induced drug elution |
US8016859B2 (en) | 2006-02-17 | 2011-09-13 | Medtronic, Inc. | Dynamic treatment system and method of use |
US7993269B2 (en) * | 2006-02-17 | 2011-08-09 | Medtronic, Inc. | Sensor and method for spinal monitoring |
US20080140057A1 (en) * | 2006-03-09 | 2008-06-12 | Searete Llc, A Limited Liability Corporation Of State Of The Delaware | Injectable controlled release fluid delivery system |
EP1999455A2 (de) * | 2006-03-10 | 2008-12-10 | Corning Incorporated | Referenzmikroplatten sowie verfahren zur herstellung und verwendung der referenzmikroplatten |
US11287421B2 (en) | 2006-03-24 | 2022-03-29 | Labrador Diagnostics Llc | Systems and methods of sample processing and fluid control in a fluidic system |
US8741230B2 (en) | 2006-03-24 | 2014-06-03 | Theranos, Inc. | Systems and methods of sample processing and fluid control in a fluidic system |
US7918796B2 (en) | 2006-04-11 | 2011-04-05 | Warsaw Orthopedic, Inc. | Volumetric measurement and visual feedback of tissues |
WO2007120381A2 (en) | 2006-04-14 | 2007-10-25 | Dexcom, Inc. | Analyte sensor |
US7879027B2 (en) * | 2006-04-24 | 2011-02-01 | Warsaw Orthopedic, Inc. | Controlled release devices for fusion of osteal structures |
US8642059B2 (en) | 2006-04-24 | 2014-02-04 | Warsaw Orthopedic, Inc. | Controlled release systems and methods for intervertebral discs |
US7771414B2 (en) * | 2006-04-24 | 2010-08-10 | Warsaw Orthopedic, Inc. | Controlled release devices for therapeutic treatments of spinal discs |
US8642060B2 (en) * | 2006-04-24 | 2014-02-04 | Warsaw Orthopedic, Inc. | Controlled release systems and methods for osteal growth |
US20070260174A1 (en) * | 2006-05-05 | 2007-11-08 | Searete Llc | Detecting a failure to maintain a regimen |
US8163237B2 (en) * | 2006-05-08 | 2012-04-24 | Becton, Dickinson And Company | Vascular access device pathogenic status indication |
US8007999B2 (en) | 2006-05-10 | 2011-08-30 | Theranos, Inc. | Real-time detection of influenza virus |
WO2008008845A2 (en) * | 2006-07-11 | 2008-01-17 | Microchips, Inc. | Multi-reservoir pump device for dialysis, biosensing, or delivery of substances |
US8064063B2 (en) * | 2006-07-20 | 2011-11-22 | Trinean Nv | Optical characterisation methods and systems |
US20080033260A1 (en) * | 2006-08-03 | 2008-02-07 | Microchips, Inc. | Cardiac Biosensor Devices and Methods |
US20080058772A1 (en) * | 2006-08-31 | 2008-03-06 | Robertson Timothy L | Personal paramedic |
US7951191B2 (en) | 2006-10-10 | 2011-05-31 | Boston Scientific Scimed, Inc. | Bifurcated stent with entire circumferential petal |
US8012744B2 (en) | 2006-10-13 | 2011-09-06 | Theranos, Inc. | Reducing optical interference in a fluidic device |
WO2008057318A1 (en) | 2006-11-01 | 2008-05-15 | The Government Of The United States Of America, As Represented By The Secretary Of The Navy | Biological fuel cells with nanporous membranes |
US20080113391A1 (en) | 2006-11-14 | 2008-05-15 | Ian Gibbons | Detection and quantification of analytes in bodily fluids |
US7842082B2 (en) | 2006-11-16 | 2010-11-30 | Boston Scientific Scimed, Inc. | Bifurcated stent |
EP3285067B1 (de) | 2006-12-14 | 2022-06-22 | Life Technologies Corporation | Vorrichtungen zur messung von analyten unter verwendung von fet-arrays |
US11339430B2 (en) | 2007-07-10 | 2022-05-24 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
US8262900B2 (en) | 2006-12-14 | 2012-09-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes using large scale FET arrays |
US8349167B2 (en) | 2006-12-14 | 2013-01-08 | Life Technologies Corporation | Methods and apparatus for detecting molecular interactions using FET arrays |
US8999636B2 (en) * | 2007-01-08 | 2015-04-07 | Toxic Report Llc | Reaction chamber |
US8568557B2 (en) | 2007-03-13 | 2013-10-29 | Heartland Technology Partners Llc | Compact wastewater concentrator using waste heat |
US8741100B2 (en) | 2007-03-13 | 2014-06-03 | Heartland Technology Partners Llc | Liquid concentrator |
US8790496B2 (en) | 2007-03-13 | 2014-07-29 | Heartland Technology Partners Llc | Compact wastewater concentrator and pollutant scrubber |
US10005678B2 (en) | 2007-03-13 | 2018-06-26 | Heartland Technology Partners Llc | Method of cleaning a compact wastewater concentrator |
US8679291B2 (en) | 2007-03-13 | 2014-03-25 | Heartland Technology Partners Llc | Compact wastewater concentrator using waste heat |
US8716028B2 (en) | 2007-04-05 | 2014-05-06 | Nalco Company | Control over hydrogen fluoride levels in oxide etchant |
US20200037875A1 (en) | 2007-05-18 | 2020-02-06 | Dexcom, Inc. | Analyte sensors having a signal-to-noise ratio substantially unaffected by non-constant noise |
EP2157907B1 (de) | 2007-06-07 | 2013-03-27 | MicroCHIPS, Inc. | Elektrochemische biosensoren und anordnungen |
US8723332B2 (en) | 2007-06-11 | 2014-05-13 | Invensas Corporation | Electrically interconnected stacked die assemblies |
DE102007031549B4 (de) * | 2007-07-06 | 2021-07-08 | Robert Bosch Gmbh | Vorrichtung aus einkristallinem Silizium und Verfahren zur Herstellung einer Vorrichtung aus einkristallinem Silizium |
CN101848757B (zh) | 2007-07-13 | 2013-12-04 | 里兰斯坦福初级大学理事会 | 用于改进的生物测定法的使用电场的方法和设备 |
DE102007032688A1 (de) * | 2007-07-13 | 2009-01-22 | Biotronik Vi Patent Ag | Implantat und System aus einem Implantat und einer Anregungsvorrichtung |
US8158430B1 (en) | 2007-08-06 | 2012-04-17 | Theranos, Inc. | Systems and methods of fluidic sample processing |
US20090042066A1 (en) * | 2007-08-10 | 2009-02-12 | Mphase Technologies, Inc. | Adjustable Barrier For Regulating Flow Of A Fluid |
US20090042065A1 (en) * | 2007-08-10 | 2009-02-12 | Mphase Technologies, Inc. | Event Activated Micro Control Devices |
US8706211B2 (en) * | 2007-08-17 | 2014-04-22 | The Invention Science Fund I, Llc | Systems, devices, and methods including catheters having self-cleaning surfaces |
US8734718B2 (en) * | 2007-08-17 | 2014-05-27 | The Invention Science Fund I, Llc | Systems, devices, and methods including catheters having an actively controllable therapeutic agent delivery component |
US9005263B2 (en) * | 2007-08-17 | 2015-04-14 | The Invention Science Fund I, Llc | System, devices, and methods including actively-controllable sterilizing excitation delivery implants |
US20090048648A1 (en) * | 2007-08-17 | 2009-02-19 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Self-sterilizing device |
US8753304B2 (en) * | 2007-08-17 | 2014-06-17 | The Invention Science Fund I, Llc | Systems, devices, and methods including catheters having acoustically actuatable waveguide components for delivering a sterilizing stimulus to a region proximate a surface of the catheter |
US20090163977A1 (en) * | 2007-08-17 | 2009-06-25 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | System, devices, and methods including sterilizing excitation delivery implants with cryptographic logic components |
US8366652B2 (en) * | 2007-08-17 | 2013-02-05 | The Invention Science Fund I, Llc | Systems, devices, and methods including infection-fighting and monitoring shunts |
US8702640B2 (en) * | 2007-08-17 | 2014-04-22 | The Invention Science Fund I, Llc | System, devices, and methods including catheters configured to monitor and inhibit biofilm formation |
US20110160644A1 (en) * | 2007-08-17 | 2011-06-30 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems, devices, and methods including catheters configured to release ultraviolet energy absorbing agents |
WO2009035849A2 (en) | 2007-09-10 | 2009-03-19 | Vertical Circuits, Inc. | Semiconductor die mount by conformal die coating |
US7959669B2 (en) | 2007-09-12 | 2011-06-14 | Boston Scientific Scimed, Inc. | Bifurcated stent with open ended side branch support |
US8778663B2 (en) * | 2007-09-18 | 2014-07-15 | Lawrence Livermore National Security, Llc. | Thermal cycler |
US20090076591A1 (en) * | 2007-09-19 | 2009-03-19 | Boston Scientific Scimed, Inc. | Stent Design Allowing Extended Release of Drug and/or Enhanced Adhesion of Polymer to OD Surface |
EP2200613B1 (de) | 2007-09-21 | 2018-09-05 | The Johns Hopkins University | Phenazin-derivate und ihre verwendungen |
DK2657699T3 (en) | 2007-10-02 | 2017-07-10 | Theranos Inc | Modular point-of-care devices and their applications |
US20090095926A1 (en) * | 2007-10-12 | 2009-04-16 | Macneish Iii William Jack | Physiological parameter detector |
JP5311801B2 (ja) * | 2007-11-09 | 2013-10-09 | キヤノン株式会社 | 浸透圧ポンプを用いた送液駆動機構および該送液駆動機構を有するマイクロチップ |
US7907330B2 (en) * | 2007-11-14 | 2011-03-15 | International Business Machines Corporation | Display element |
US8551556B2 (en) * | 2007-11-20 | 2013-10-08 | Palo Alto Research Center Incorporated | Method for obtaining controlled sidewall profile in print-patterned structures |
US7833266B2 (en) | 2007-11-28 | 2010-11-16 | Boston Scientific Scimed, Inc. | Bifurcated stent with drug wells for specific ostial, carina, and side branch treatment |
US7722661B2 (en) * | 2007-12-19 | 2010-05-25 | Boston Scientific Scimed, Inc. | Stent |
US8268604B2 (en) * | 2007-12-20 | 2012-09-18 | Abbott Point Of Care Inc. | Compositions for forming immobilized biological layers for sensing |
US8241697B2 (en) | 2007-12-20 | 2012-08-14 | Abbott Point Of Care Inc. | Formation of immobilized biological layers for sensing |
US8277501B2 (en) | 2007-12-21 | 2012-10-02 | Boston Scientific Scimed, Inc. | Bi-stable bifurcated stent petal geometry |
JP2011510750A (ja) | 2008-01-29 | 2011-04-07 | クライマン、ギルバート・エイチ | 薬物送達デバイス、キット及びそれらの方法 |
US20090198321A1 (en) * | 2008-02-01 | 2009-08-06 | Boston Scientific Scimed, Inc. | Drug-Coated Medical Devices for Differential Drug Release |
JP4577370B2 (ja) * | 2008-02-12 | 2010-11-10 | 株式会社デンソー | センサ装置およびその製造方法 |
JP5763924B2 (ja) | 2008-03-12 | 2015-08-12 | インヴェンサス・コーポレーション | ダイアセンブリを電気的に相互接続して取り付けられたサポート |
US8682408B2 (en) | 2008-03-28 | 2014-03-25 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
US8583204B2 (en) | 2008-03-28 | 2013-11-12 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
US11730407B2 (en) | 2008-03-28 | 2023-08-22 | Dexcom, Inc. | Polymer membranes for continuous analyte sensors |
US20090259112A1 (en) * | 2008-04-09 | 2009-10-15 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Sensors |
US20090259217A1 (en) * | 2008-04-09 | 2009-10-15 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Methods and systems associated with delivery of one or more agents to an individual |
US7863159B2 (en) | 2008-06-19 | 2011-01-04 | Vertical Circuits, Inc. | Semiconductor die separation method |
US9153517B2 (en) | 2008-05-20 | 2015-10-06 | Invensas Corporation | Electrical connector between die pad and z-interconnect for stacked die assemblies |
US8932340B2 (en) | 2008-05-29 | 2015-01-13 | Boston Scientific Scimed, Inc. | Bifurcated stent and delivery system |
WO2010008480A2 (en) | 2008-06-25 | 2010-01-21 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes using large scale fet arrays |
CA2668792C (en) * | 2008-06-30 | 2017-08-01 | Tyco Healthcare Group Lp | Valve assembly including a dissolvable valve member |
US7951193B2 (en) * | 2008-07-23 | 2011-05-31 | Boston Scientific Scimed, Inc. | Drug-eluting stent |
DE102008040788A1 (de) * | 2008-07-28 | 2010-02-11 | Biotronik Crm Patent Ag | Vorrichtung und Verfahren zur Erfassung der Strömungsgeschwindigkeit eines Blutstromes und Herz-/Kreislauf-Unterstützungsvorrichtung |
US20100028403A1 (en) * | 2008-07-31 | 2010-02-04 | Boston Scientific Scimed, Inc. | Medical devices for therapeutic agent delivery |
US8700114B2 (en) * | 2008-07-31 | 2014-04-15 | Medtronic Minmed, Inc. | Analyte sensor apparatuses comprising multiple implantable sensor elements and methods for making and using them |
US20100025238A1 (en) * | 2008-07-31 | 2010-02-04 | Medtronic Minimed, Inc. | Analyte sensor apparatuses having improved electrode configurations and methods for making and using them |
US20100070188A1 (en) * | 2008-08-08 | 2010-03-18 | Neal Solomon | Intelligent medical device system for on-demand diagnostics |
US8560039B2 (en) | 2008-09-19 | 2013-10-15 | Dexcom, Inc. | Particle-containing membrane and particulate electrode for analyte sensors |
TWI361169B (en) * | 2008-10-20 | 2012-04-01 | Nat Chip Implementation Ct Nat Applied Res Lab | Biosensor package structure with micro-fluidic channel |
US20100137143A1 (en) | 2008-10-22 | 2010-06-03 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
US20100301398A1 (en) | 2009-05-29 | 2010-12-02 | Ion Torrent Systems Incorporated | Methods and apparatus for measuring analytes |
US20100136097A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems for modulating inflammation |
US20100137246A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Anti-inflammatory compositions and methods |
US20100137247A1 (en) * | 2008-12-02 | 2010-06-03 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Anti-inflammatory compositions and methods |
US20110208023A1 (en) * | 2008-12-04 | 2011-08-25 | Goodall Eleanor V | Systems, devices, and methods including implantable devices with anti-microbial properties |
US20110152751A1 (en) * | 2008-12-04 | 2011-06-23 | Searete Llc, A Limited Liability Corporation Of The State Of Delaware | Systems, devices, and methods including catheters having UV-Energy emitting coatings |
US20110208021A1 (en) * | 2008-12-04 | 2011-08-25 | Goodall Eleanor V | Systems, devices, and methods including implantable devices with anti-microbial properties |
US9474831B2 (en) | 2008-12-04 | 2016-10-25 | Gearbox, Llc | Systems, devices, and methods including implantable devices with anti-microbial properties |
US20110208026A1 (en) * | 2008-12-04 | 2011-08-25 | Goodall Eleanor V | Systems, devices, and methods including implantable devices with anti-microbial properties |
US8285387B2 (en) | 2008-12-12 | 2012-10-09 | Microchips, Inc. | Wireless communication with a medical implant |
US7838715B2 (en) * | 2009-01-21 | 2010-11-23 | Palo Alto Research Center Incorporated | Drug deactivation system and method of deactivating a drug using the same |
US8236238B2 (en) | 2009-01-21 | 2012-08-07 | Palo Alto Research Center Incorporated | Drug deactivation system |
US9480795B2 (en) * | 2009-01-21 | 2016-11-01 | Palo Alto Research Center Incorporated | Sensor system for drug delivery device, drug delivery device having the same and method of using the same |
US8410690B2 (en) * | 2009-02-13 | 2013-04-02 | Qualcomm Mems Technologies, Inc. | Display device with desiccant |
US8124953B2 (en) | 2009-03-12 | 2012-02-28 | Infineon Technologies Ag | Sensor device having a porous structure element |
EP3138603A1 (de) * | 2009-03-20 | 2017-03-08 | Incube Labs, Llc | Feststoffverabreichungsvorrichtung, formulierungen und verfahren zur verwendung |
US9176090B2 (en) * | 2009-04-07 | 2015-11-03 | Panasonic Healthcare Holdings Co., Ltd. | Sensor chip, and measurement device and blood test device in which this sensor chip is used |
US8278758B1 (en) * | 2009-04-29 | 2012-10-02 | Massachusetts Institute Of Technology | Multilevel reservoirs for integrated circuit interconnects |
US8574835B2 (en) | 2009-05-29 | 2013-11-05 | Life Technologies Corporation | Scaffolded nucleic acid polymer particles and methods of making and using |
US20120261274A1 (en) | 2009-05-29 | 2012-10-18 | Life Technologies Corporation | Methods and apparatus for measuring analytes |
US8673627B2 (en) | 2009-05-29 | 2014-03-18 | Life Technologies Corporation | Apparatus and methods for performing electrochemical reactions |
US8776573B2 (en) | 2009-05-29 | 2014-07-15 | Life Technologies Corporation | Methods and apparatus for measuring analytes |
TW201043224A (en) * | 2009-06-06 | 2010-12-16 | Univ Nat Taiwan | Drug delivery chip and fabricating method thereof |
KR101715426B1 (ko) | 2009-06-26 | 2017-03-10 | 인벤사스 코포레이션 | 지그재그 구조로 적층된 다이용 전기 인터커넥트 |
US8664963B2 (en) * | 2009-07-24 | 2014-03-04 | Alliance For Sustainable Energy, Llc | Test device for measuring permeability of a barrier material |
CA2770246A1 (en) * | 2009-08-08 | 2011-02-17 | Sanofi-Aventis Deutschland Gmbh | Implantable sensor device and medical delivery device connectable to such a sensor device |
EP2496936B1 (de) | 2009-10-16 | 2018-02-21 | Microchips Biotech, Inc. | Mehrkanal-potentiostat für eine biosensoranordnung und verwendungsverfahren |
NZ624935A (en) | 2009-10-19 | 2016-01-29 | Theranos Inc | Integrated health data capture and analysis system |
WO2011056668A2 (en) | 2009-10-27 | 2011-05-12 | Vertical Circuits, Inc. | Selective die electrical insulation additive process |
MY147335A (en) * | 2009-10-27 | 2012-11-30 | Mimos Berhad | An integrated packaged environmental sensor and roic and a method of fabricating the same |
TWI544604B (zh) | 2009-11-04 | 2016-08-01 | 英維瑟斯公司 | 具有降低應力電互連的堆疊晶粒總成 |
US9389158B2 (en) | 2010-02-12 | 2016-07-12 | Dan Angelescu | Passive micro-vessel and sensor |
US9772261B2 (en) | 2010-02-12 | 2017-09-26 | Fluidion Sas | Passive micro-vessel and sensor |
US9869613B2 (en) | 2010-02-12 | 2018-01-16 | Fluidion Sas | Passive micro-vessel and sensor |
WO2011100509A2 (en) * | 2010-02-12 | 2011-08-18 | Dan Angelescu | Passive micro-vessel and sensor |
US10408040B2 (en) | 2010-02-12 | 2019-09-10 | Fluidion Sas | Passive micro-vessel and sensor |
US8828246B2 (en) | 2010-02-18 | 2014-09-09 | Anpac Bio-Medical Science Co., Ltd. | Method of fabricating micro-devices |
US8810236B2 (en) * | 2010-03-09 | 2014-08-19 | Nokia Corporation | Apparatus and associated methods |
TWI463648B (zh) | 2010-06-30 | 2014-12-01 | Life Technologies Corp | 陣列行積分器 |
CN103154718B (zh) | 2010-06-30 | 2015-09-23 | 生命科技公司 | 感测离子的电荷堆积电路和方法 |
CN103080739B (zh) | 2010-06-30 | 2016-12-21 | 生命科技公司 | 用于测试isfet阵列的方法和装置 |
US11307166B2 (en) | 2010-07-01 | 2022-04-19 | Life Technologies Corporation | Column ADC |
US8653567B2 (en) | 2010-07-03 | 2014-02-18 | Life Technologies Corporation | Chemically sensitive sensor with lightly doped drains |
GB201012490D0 (en) * | 2010-07-26 | 2010-09-08 | Randox Lab Ltd | Sealed well assembly, cartridge thereof, and apparatus and method for opening a sealed well assembly |
EP2600761A4 (de) | 2010-08-06 | 2014-08-13 | Microchips Inc | Biosensormembranzusammensetzung, biosensor und herstellungsverfahren dafür |
WO2012035429A2 (en) | 2010-09-13 | 2012-03-22 | The University Of British Columbia | Remotely controlled drug delivery systems |
US9618475B2 (en) | 2010-09-15 | 2017-04-11 | Life Technologies Corporation | Methods and apparatus for measuring analytes |
JP5913323B2 (ja) | 2010-09-24 | 2016-04-27 | ライフ テクノロジーズ コーポレーション | マッチドペアトランジスタ回路 |
US9687182B2 (en) * | 2010-10-07 | 2017-06-27 | Biotronik Se & Co. Kg | Medical sensor system for detecting a feature in a body |
GB2489193A (en) * | 2010-10-29 | 2012-09-26 | Univ Warwick | Ingestible sensor device to detect gases and VOCs in the gastrointestinal tract |
CN106290159A (zh) | 2011-01-21 | 2017-01-04 | 提拉诺斯公司 | 样品使用最大化的***和方法 |
US8721771B2 (en) | 2011-01-21 | 2014-05-13 | Heartland Technology Partners Llc | Condensation plume mitigation system for exhaust stacks |
WO2012158202A2 (en) * | 2011-05-19 | 2012-11-22 | Abbott Diabetes Care Inc. | Analyte sensors and methods of fabricating them |
US9853325B2 (en) | 2011-06-29 | 2017-12-26 | Space Charge, LLC | Rugged, gel-free, lithium-free, high energy density solid-state electrochemical energy storage devices |
US10658705B2 (en) | 2018-03-07 | 2020-05-19 | Space Charge, LLC | Thin-film solid-state energy storage devices |
US11527774B2 (en) | 2011-06-29 | 2022-12-13 | Space Charge, LLC | Electrochemical energy storage devices |
US10601074B2 (en) | 2011-06-29 | 2020-03-24 | Space Charge, LLC | Rugged, gel-free, lithium-free, high energy density solid-state electrochemical energy storage devices |
US11996517B2 (en) | 2011-06-29 | 2024-05-28 | Space Charge, LLC | Electrochemical energy storage devices |
US9448198B2 (en) * | 2011-07-05 | 2016-09-20 | Stmicroelectronics Pte Ltd. | Microsensor with integrated temperature control |
DE102011107547B4 (de) * | 2011-07-11 | 2015-08-06 | Krohne Messtechnik Gmbh | Druckaufnehmer für ein Vortex-Durchflussmessgerät, Vortex-Durchflussmessgerät und Verfahren zur Herstellung eines solchen Druckaufnehmers |
PT2747642T (pt) | 2011-08-25 | 2021-07-27 | Microchips Biotech Inc | Dispositivos de contenção eficientes em termos de espaço e método de criação dos mesmos |
US10427153B2 (en) | 2011-08-25 | 2019-10-01 | Microchips Biotech, Inc. | Systems and methods for sealing a plurality of reservoirs of a microchip element with a sealing grid |
WO2013036598A1 (en) * | 2011-09-06 | 2013-03-14 | Telecardia, Inc. | Measurement device with sensor array |
US9664702B2 (en) | 2011-09-25 | 2017-05-30 | Theranos, Inc. | Fluid handling apparatus and configurations |
US20140170735A1 (en) | 2011-09-25 | 2014-06-19 | Elizabeth A. Holmes | Systems and methods for multi-analysis |
US9619627B2 (en) | 2011-09-25 | 2017-04-11 | Theranos, Inc. | Systems and methods for collecting and transmitting assay results |
US8475739B2 (en) | 2011-09-25 | 2013-07-02 | Theranos, Inc. | Systems and methods for fluid handling |
US9268915B2 (en) | 2011-09-25 | 2016-02-23 | Theranos, Inc. | Systems and methods for diagnosis or treatment |
US8840838B2 (en) | 2011-09-25 | 2014-09-23 | Theranos, Inc. | Centrifuge configurations |
US9632102B2 (en) | 2011-09-25 | 2017-04-25 | Theranos, Inc. | Systems and methods for multi-purpose analysis |
US9250229B2 (en) | 2011-09-25 | 2016-02-02 | Theranos, Inc. | Systems and methods for multi-analysis |
US10012664B2 (en) | 2011-09-25 | 2018-07-03 | Theranos Ip Company, Llc | Systems and methods for fluid and component handling |
US9810704B2 (en) | 2013-02-18 | 2017-11-07 | Theranos, Inc. | Systems and methods for multi-analysis |
US9296624B2 (en) | 2011-10-11 | 2016-03-29 | Heartland Technology Partners Llc | Portable compact wastewater concentrator |
US9970984B2 (en) | 2011-12-01 | 2018-05-15 | Life Technologies Corporation | Method and apparatus for identifying defects in a chemical sensor array |
US8747748B2 (en) | 2012-01-19 | 2014-06-10 | Life Technologies Corporation | Chemical sensor with conductive cup-shaped sensor surface |
US8821798B2 (en) | 2012-01-19 | 2014-09-02 | Life Technologies Corporation | Titanium nitride as sensing layer for microwell structure |
US10300281B2 (en) | 2012-03-09 | 2019-05-28 | Mayo Foundation For Medical Education And Research | Modulating afferent signals to treat medical conditions |
US8808497B2 (en) | 2012-03-23 | 2014-08-19 | Heartland Technology Partners Llc | Fluid evaporator for an open fluid reservoir |
JP5579218B2 (ja) * | 2012-03-28 | 2014-08-27 | 株式会社東芝 | 圧力検知素子の製造方法 |
US8685708B2 (en) | 2012-04-18 | 2014-04-01 | Pathogenetix, Inc. | Device for preparing a sample |
US8786331B2 (en) | 2012-05-29 | 2014-07-22 | Life Technologies Corporation | System for reducing noise in a chemical sensor array |
US20130330531A1 (en) * | 2012-06-06 | 2013-12-12 | Cheil Industries, Inc. | Barrier stacks and methods of making the same |
US8790400B2 (en) | 2012-06-13 | 2014-07-29 | Elwha Llc | Breast implant with covering and analyte sensors responsive to external power source |
US9144488B2 (en) | 2012-06-13 | 2015-09-29 | Elwha Llc | Breast implant with analyte sensors responsive to external power source |
US9144489B2 (en) | 2012-06-13 | 2015-09-29 | Elwha Llc | Breast implant with covering, analyte sensors and internal power source |
US8795359B2 (en) | 2012-06-13 | 2014-08-05 | Elwha Llc | Breast implant with regionalized analyte sensors and internal power source |
US9211185B2 (en) | 2012-06-13 | 2015-12-15 | Elwha Llc | Breast implant with analyte sensors and internal power source |
US8808373B2 (en) | 2012-06-13 | 2014-08-19 | Elwha Llc | Breast implant with regionalized analyte sensors responsive to external power source |
US9320465B2 (en) | 2012-06-25 | 2016-04-26 | International Business Machines Corporation | Bio-chips and nano-biochips |
US9136160B2 (en) * | 2012-06-29 | 2015-09-15 | Institute of Microelectronics, Chinese Academy of Sciences | Solid hole array and method for forming the same |
US8741101B2 (en) | 2012-07-13 | 2014-06-03 | Heartland Technology Partners Llc | Liquid concentrator |
TWI464388B (zh) * | 2012-08-17 | 2014-12-11 | Wistron Corp | 光校正裝置、生物檢測校正系統及其操作方法 |
WO2014045762A1 (ja) * | 2012-09-21 | 2014-03-27 | テルモ株式会社 | 蛍光センサ及びセンサシステム |
US9297816B1 (en) * | 2012-12-21 | 2016-03-29 | University Of South Florida | Devices and methods for measuring blood coagulation |
CA2895235C (en) | 2012-12-21 | 2020-12-29 | Microchips Biotech, Inc. | Implantable medical device for minimally-invasive insertion |
US9080968B2 (en) | 2013-01-04 | 2015-07-14 | Life Technologies Corporation | Methods and systems for point of use removal of sacrificial material |
US9841398B2 (en) | 2013-01-08 | 2017-12-12 | Life Technologies Corporation | Methods for manufacturing well structures for low-noise chemical sensors |
US8962366B2 (en) | 2013-01-28 | 2015-02-24 | Life Technologies Corporation | Self-aligned well structures for low-noise chemical sensors |
EP2953677B1 (de) * | 2013-02-06 | 2017-12-20 | Dan Angelescu | Passives mikrogefäss und sensor zur bestimmung der viscosität |
US8585869B1 (en) | 2013-02-07 | 2013-11-19 | Heartland Technology Partners Llc | Multi-stage wastewater treatment system |
US9199861B2 (en) | 2013-02-07 | 2015-12-01 | Heartland Technology Partners Llc | Wastewater processing systems for power plants and other industrial sources |
MY175542A (en) | 2013-02-28 | 2020-07-01 | Microchips Biotech Inc | Implantable medical device for minimally-invasive insertion |
US10849540B2 (en) | 2013-03-11 | 2020-12-01 | The University Of Toledo | Biosensor device to target analytes in situ, in vivo, and/or in real time, and methods of making and using the same |
US8963216B2 (en) | 2013-03-13 | 2015-02-24 | Life Technologies Corporation | Chemical sensor with sidewall spacer sensor surface |
US8841217B1 (en) | 2013-03-13 | 2014-09-23 | Life Technologies Corporation | Chemical sensor with protruded sensor surface |
JP2016510895A (ja) | 2013-03-15 | 2016-04-11 | ライフ テクノロジーズ コーポレーション | 一貫性のあるセンサ表面積を有する化学センサ |
US9835585B2 (en) | 2013-03-15 | 2017-12-05 | Life Technologies Corporation | Chemical sensor with protruded sensor surface |
WO2014149779A1 (en) | 2013-03-15 | 2014-09-25 | Life Technologies Corporation | Chemical device with thin conductive element |
US20140336063A1 (en) | 2013-05-09 | 2014-11-13 | Life Technologies Corporation | Windowed Sequencing |
KR20140136277A (ko) * | 2013-05-20 | 2014-11-28 | 삼성전자주식회사 | 미세유동장치 |
US10458942B2 (en) | 2013-06-10 | 2019-10-29 | Life Technologies Corporation | Chemical sensor array having multiple sensors per well |
US9724692B2 (en) * | 2013-06-27 | 2017-08-08 | Quark Biosciences, Inc. | Multiplex slide plate |
US10415084B2 (en) | 2013-06-27 | 2019-09-17 | Quark Biosciences Taiwan, Inc. | Multiplex slide plate device and operation method thereof |
US9937124B2 (en) | 2014-09-11 | 2018-04-10 | International Business Machines Corporation | Microchip substance delivery devices having low-power electromechanical release mechanisms |
US9677998B2 (en) | 2014-12-18 | 2017-06-13 | Ecolab Usa Inc. | Control over etching molecule levels in etching compositions |
EP3234576B1 (de) | 2014-12-18 | 2023-11-22 | Life Technologies Corporation | Integrierte schaltung mit hoher datenrate und mit transmitterkonfiguration |
US10077472B2 (en) | 2014-12-18 | 2018-09-18 | Life Technologies Corporation | High data rate integrated circuit with power management |
TWI684004B (zh) | 2014-12-18 | 2020-02-01 | 美商生命技術公司 | 用於使用大規模fet陣列量測分析物之方法及設備 |
US9759651B2 (en) | 2014-12-23 | 2017-09-12 | Magellan Diagnostics, Inc. | Combination optical hemoglobin and electrochemical lead assay |
JP6607593B2 (ja) * | 2015-02-10 | 2019-11-20 | 国立大学法人 筑波大学 | 脱ミエリン化剤及び電極 |
US9798886B2 (en) | 2015-07-08 | 2017-10-24 | International Business Machines Corporation | Bio-medical sensing platform |
US9871019B2 (en) | 2015-07-17 | 2018-01-16 | Invensas Corporation | Flipped die stack assemblies with leadframe interconnects |
US9825002B2 (en) | 2015-07-17 | 2017-11-21 | Invensas Corporation | Flipped die stack |
US9490195B1 (en) | 2015-07-17 | 2016-11-08 | Invensas Corporation | Wafer-level flipped die stacks with leadframes or metal foil interconnects |
US10881788B2 (en) | 2015-10-30 | 2021-01-05 | International Business Machines Corporation | Delivery device including reactive material for programmable discrete delivery of a substance |
JP6918366B2 (ja) * | 2015-12-11 | 2021-08-11 | セライプ アーゲーSeraip Ag | 患者へ流体を送達するための、及び/又は、患者から流体を採取するための、流体インターフェース・デバイス |
US9508691B1 (en) | 2015-12-16 | 2016-11-29 | Invensas Corporation | Flipped die stacks with multiple rows of leadframe interconnects |
US10566310B2 (en) | 2016-04-11 | 2020-02-18 | Invensas Corporation | Microelectronic packages having stacked die and wire bond interconnects |
US9595511B1 (en) | 2016-05-12 | 2017-03-14 | Invensas Corporation | Microelectronic packages and assemblies with improved flyby signaling operation |
US9728524B1 (en) | 2016-06-30 | 2017-08-08 | Invensas Corporation | Enhanced density assembly having microelectronic packages mounted at substantial angle to board |
CN107782767B (zh) * | 2016-08-26 | 2022-01-07 | 深迪半导体(绍兴)有限公司 | 一种气体传感器加热盘及加工方法 |
US10620151B2 (en) | 2016-08-30 | 2020-04-14 | Analog Devices Global | Electrochemical sensor, and a method of forming an electrochemical sensor |
US11268927B2 (en) | 2016-08-30 | 2022-03-08 | Analog Devices International Unlimited Company | Electrochemical sensor, and a method of forming an electrochemical sensor |
US10864359B2 (en) * | 2017-05-02 | 2020-12-15 | Bernard Fryshman | Induction heating systems |
CN108968976B (zh) | 2017-05-31 | 2022-09-13 | 心脏起搏器股份公司 | 具有化学传感器的植入式医疗设备 |
US11304893B2 (en) | 2017-07-24 | 2022-04-19 | California Institute Of Technology | Low power, chemically amplified, electrically removable barrier |
US12004853B2 (en) | 2017-07-26 | 2024-06-11 | Cardiac Pacemakers, Inc. | Systems and methods for disambiguation of posture |
CN109381195B (zh) | 2017-08-10 | 2023-01-10 | 心脏起搏器股份公司 | 包括电解质传感器融合的***和方法 |
CN109419515B (zh) | 2017-08-23 | 2023-03-24 | 心脏起搏器股份公司 | 具有分级激活的可植入化学传感器 |
US20210145335A1 (en) * | 2017-08-24 | 2021-05-20 | The Regents Of The University Of Michigan | Precision bio-chemotronic system |
CN109864746B (zh) | 2017-12-01 | 2023-09-29 | 心脏起搏器股份公司 | 用于医学装置的多模式分析物传感器 |
CN109864747B (zh) | 2017-12-05 | 2023-08-25 | 心脏起搏器股份公司 | 多模式分析物传感器光电子接口 |
US10520673B2 (en) * | 2017-12-28 | 2019-12-31 | Lightwave Logic Inc. | Protection layers for polymer modulators/waveguides |
CN111918689B (zh) * | 2018-02-02 | 2023-05-19 | 麦克罗博医疗公司 | 可植入导管组件 |
US11022579B2 (en) | 2018-02-05 | 2021-06-01 | Analog Devices International Unlimited Company | Retaining cap |
US11109784B2 (en) | 2018-04-09 | 2021-09-07 | California Institute Of Technology | Metal-enzyme sandwich layers |
JP6683230B2 (ja) * | 2018-09-27 | 2020-04-15 | 横河電機株式会社 | 測定装置 |
KR102631453B1 (ko) | 2018-10-02 | 2024-01-31 | 삼성디스플레이 주식회사 | 잉크젯 프린팅 장치 |
US11473191B2 (en) * | 2019-02-27 | 2022-10-18 | Applied Materials, Inc. | Method for creating a dielectric filled nanostructured silica substrate for flat optical devices |
US11517831B2 (en) * | 2019-06-25 | 2022-12-06 | George Andrew Rabroker | Abatement system for pyrophoric chemicals and method of use |
WO2021119452A1 (en) * | 2019-12-13 | 2021-06-17 | Massachusetts Institute Of Technology | Dispensing device with membrane based trigger |
US11636870B2 (en) | 2020-08-20 | 2023-04-25 | Denso International America, Inc. | Smoking cessation systems and methods |
US12017506B2 (en) | 2020-08-20 | 2024-06-25 | Denso International America, Inc. | Passenger cabin air control systems and methods |
US11813926B2 (en) | 2020-08-20 | 2023-11-14 | Denso International America, Inc. | Binding agent and olfaction sensor |
US11932080B2 (en) | 2020-08-20 | 2024-03-19 | Denso International America, Inc. | Diagnostic and recirculation control systems and methods |
US11828210B2 (en) | 2020-08-20 | 2023-11-28 | Denso International America, Inc. | Diagnostic systems and methods of vehicles using olfaction |
US11760170B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Olfaction sensor preservation systems and methods |
US11760169B2 (en) | 2020-08-20 | 2023-09-19 | Denso International America, Inc. | Particulate control systems and methods for olfaction sensors |
US11881093B2 (en) | 2020-08-20 | 2024-01-23 | Denso International America, Inc. | Systems and methods for identifying smoking in vehicles |
Family Cites Families (230)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US538709A (en) * | 1895-05-07 | Desk-ruler | ||
US3216411A (en) * | 1962-05-16 | 1965-11-09 | Nippon Electric Co | Ingestible transmitter for the detection of bleeding in the gastrointestinal canal |
US3692027A (en) | 1971-04-23 | 1972-09-19 | Everett H Ellinwood Jr | Implanted medication dispensing device and method |
US3791377A (en) * | 1971-06-30 | 1974-02-12 | T Norby | Radio capsule battery |
US3921636A (en) | 1973-01-15 | 1975-11-25 | Alza Corp | Novel drug delivery device |
US4003379A (en) * | 1974-04-23 | 1977-01-18 | Ellinwood Jr Everett H | Apparatus and method for implanted self-powered medication dispensing |
US4089734A (en) * | 1974-09-16 | 1978-05-16 | Raytheon Company | Integrated circuit fusing technique |
US3952741A (en) * | 1975-01-09 | 1976-04-27 | Bend Research Inc. | Controlled release delivery system by an osmotic bursting mechanism |
US4209894A (en) | 1978-04-27 | 1980-07-01 | Texas Instruments Incorporated | Fusible-link semiconductor memory |
US4345981A (en) * | 1978-11-24 | 1982-08-24 | Diamond Shamrock Corporation | Anodically polarized surface for biofouling and scale control |
US4360019A (en) | 1979-02-28 | 1982-11-23 | Andros Incorporated | Implantable infusion device |
DE2911558A1 (de) | 1979-03-23 | 1980-09-25 | Alza Corp | Abgabevorrichtung fuer fluessigkeiten |
US4731051A (en) * | 1979-04-27 | 1988-03-15 | The Johns Hopkins University | Programmable control means for providing safe and controlled medication infusion |
JPS57163309A (en) | 1981-04-01 | 1982-10-07 | Olympus Optical Co Ltd | Capsule apparatus for medical use |
US4571543A (en) * | 1983-03-28 | 1986-02-18 | Southwest Medical Products, Inc. | Specific material detection and measuring device |
US4856188A (en) * | 1984-10-12 | 1989-08-15 | Drug Delivery Systems Inc. | Method for making disposable and/or replenishable transdermal drug applicators |
GB8422876D0 (en) | 1984-09-11 | 1984-10-17 | Secr Defence | Silicon implant devices |
US4585652A (en) | 1984-11-19 | 1986-04-29 | Regents Of The University Of Minnesota | Electrochemical controlled release drug delivery system |
DE3602796A1 (de) * | 1986-01-30 | 1987-08-06 | Messerschmitt Boelkow Blohm | Sensorelement mit einem gedaechtnis fuer anormale aenderungen der einfallenden lichtintensitaet |
CH670381A5 (de) | 1986-05-05 | 1989-06-15 | Sulzer Ag | |
US4865813A (en) * | 1986-07-07 | 1989-09-12 | Leon Luis P | Disposable analytical device |
US5042975A (en) | 1986-07-25 | 1991-08-27 | Rutgers, The State University Of New Jersey | Iontotherapeutic device and process and iontotherapeutic unit dose |
US4731049A (en) | 1987-01-30 | 1988-03-15 | Ionics, Incorporated | Cell for electrically controlled transdermal drug delivery |
US4874500A (en) | 1987-07-15 | 1989-10-17 | Sri International | Microelectrochemical sensor and sensor array |
US5387419A (en) | 1988-03-31 | 1995-02-07 | The University Of Michigan | System for controlled release of antiarrhythmic agents |
DE58907327D1 (de) | 1988-06-01 | 1994-05-05 | Deutsche Aerospace | Vorrichtung mit Träger besonderer Struktur zur Aufnahme, Untersuchung und Behandlung von Proben. |
US5252294A (en) | 1988-06-01 | 1993-10-12 | Messerschmitt-Bolkow-Blohm Gmbh | Micromechanical structure |
DD296998A5 (de) | 1988-07-05 | 1991-12-19 | Tu Karl-Marx-Stadt,Sektion Informationstechnik Wb Geraetetechnik,De | Anordnung zur stroemungswiderstandsveraenderung in von fluessigkeiten oder gasen durchstroemten anordnungen |
US5261870A (en) * | 1988-10-26 | 1993-11-16 | Biopore, Inc. | Separation barrier with plugged pores |
US5200051A (en) | 1988-11-14 | 1993-04-06 | I-Stat Corporation | Wholly microfabricated biosensors and process for the manufacture and use thereof |
DE3908822A1 (de) | 1989-03-18 | 1990-09-20 | Voss Gunther Meinhardt | Neue mikro-wirkstoffkapsel, die zeitlich und volumenmaessig kontrolliert, gezielt arzneistoffe abgeben kann |
DE3915920A1 (de) * | 1989-05-16 | 1990-11-22 | Messerschmitt Boelkow Blohm | Mikromechanische struktur |
US5101814A (en) | 1989-08-11 | 1992-04-07 | Palti Yoram Prof | System for monitoring and controlling blood glucose |
US5041107A (en) | 1989-10-06 | 1991-08-20 | Cardiac Pacemakers, Inc. | Electrically controllable, non-occluding, body implantable drug delivery system |
GB9001234D0 (en) * | 1990-01-19 | 1990-03-21 | Morris Christopher P | Improvements relating to conveying and separation apparatus |
US5229131A (en) * | 1990-02-05 | 1993-07-20 | University Of Michigan | Pulsatile drug delivery system |
US5147297A (en) | 1990-05-07 | 1992-09-15 | Alza Corporation | Iontophoretic delivery device |
US5143066A (en) * | 1990-05-08 | 1992-09-01 | University Of Pittsburgh | Optical fiber sensors for continuous monitoring of biochemicals and related method |
US5170801A (en) | 1990-10-02 | 1992-12-15 | Glaxo Inc. | Medical capsule device actuated by radio-frequency (rf) signal |
US5196002A (en) | 1990-10-09 | 1993-03-23 | University Of Utah Research Foundation | Implantable drug delivery system with piston acutation |
US5167625A (en) | 1990-10-09 | 1992-12-01 | Sarcos Group | Multiple vesicle implantable drug delivery system |
US5493177A (en) * | 1990-12-03 | 1996-02-20 | The Regents Of The University Of California | Sealed micromachined vacuum and gas filled devices |
US5102402A (en) | 1991-01-04 | 1992-04-07 | Medtronic, Inc. | Releasable coatings on balloon catheters |
US5893840A (en) | 1991-01-04 | 1999-04-13 | Medtronic, Inc. | Releasable microcapsules on balloon catheters |
US5254081A (en) | 1991-02-01 | 1993-10-19 | Empi, Inc. | Multiple site drug iontophoresis electronic device and method |
US5391164A (en) | 1991-05-03 | 1995-02-21 | Giampapa; Vincent C. | Subcutaneous implantable multiple-agent delivery system |
US5101874A (en) * | 1991-05-17 | 1992-04-07 | David R. Webb Co., Inc. | Tangential rotary slicer |
US5279607A (en) | 1991-05-30 | 1994-01-18 | The State University Of New York | Telemetry capsule and process |
AU2563292A (en) | 1991-08-26 | 1993-03-16 | Rutgers, The State University Of New Jersey | Iontotherapeutic device and process |
US5605662A (en) * | 1993-11-01 | 1997-02-25 | Nanogen, Inc. | Active programmable electronic devices for molecular biological analysis and diagnostics |
CA2123428A1 (en) * | 1991-11-13 | 1993-05-27 | John Corish | Drug delivery device |
US5193539A (en) * | 1991-12-18 | 1993-03-16 | Alfred E. Mann Foundation For Scientific Research | Implantable microstimulator |
US5262127A (en) * | 1992-02-12 | 1993-11-16 | The Regents Of The University Of Michigan | Solid state chemical micro-reservoirs |
US5198002A (en) * | 1992-03-12 | 1993-03-30 | The United States Of America As Represented By The United States Department Of Energy | Gas stream clean-up filter and method for forming same |
US5429822A (en) | 1992-03-13 | 1995-07-04 | Cambridge Scientific, Inc. | Biodegradable bursting release system |
US5756117A (en) | 1992-04-08 | 1998-05-26 | International Medical Asscociates, Inc. | Multidose transdermal drug delivery system |
US5304293A (en) | 1992-05-11 | 1994-04-19 | Teknekron Sensor Development Corporation | Microsensors for gaseous and vaporous species |
US5318557A (en) | 1992-07-13 | 1994-06-07 | Elan Medical Technologies Limited | Medication administering device |
US5288463A (en) * | 1992-10-23 | 1994-02-22 | Eastman Kodak Company | Positive flow control in an unvented container |
US5449382A (en) | 1992-11-04 | 1995-09-12 | Dayton; Michael P. | Minimally invasive bioactivated endoprosthesis for vessel repair |
US6256522B1 (en) * | 1992-11-23 | 2001-07-03 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Sensors for continuous monitoring of biochemicals and related method |
US5380272A (en) * | 1993-01-28 | 1995-01-10 | Scientific Innovations Ltd. | Transcutaneous drug delivery applicator |
US5368588A (en) | 1993-02-26 | 1994-11-29 | Bettinger; David S. | Parenteral fluid medication reservoir pump |
US5366454A (en) | 1993-03-17 | 1994-11-22 | La Corporation De L'ecole Polytechnique | Implantable medication dispensing device |
US5336454A (en) * | 1993-03-26 | 1994-08-09 | Advanced Ceramics Corporation | Ceramic composite and method |
US5474527A (en) | 1993-03-29 | 1995-12-12 | Bettinger; David S. | Positive displacement transdermal system |
US5427585A (en) | 1993-03-29 | 1995-06-27 | Bettinger; David S. | On-demand iontophoretic system |
US5327585A (en) * | 1993-05-05 | 1994-07-12 | Karlan Edward J | Cool cap |
US5368704A (en) | 1993-08-06 | 1994-11-29 | Teknekron Corporation | Micro-electrochemical valves and method |
US5900160A (en) | 1993-10-04 | 1999-05-04 | President And Fellows Of Harvard College | Methods of etching articles via microcontact printing |
US5374395A (en) * | 1993-10-14 | 1994-12-20 | Amoco Corporation | Diagnostics instrument |
US5518680A (en) | 1993-10-18 | 1996-05-21 | Massachusetts Institute Of Technology | Tissue regeneration matrices by solid free form fabrication techniques |
US5490962A (en) | 1993-10-18 | 1996-02-13 | Massachusetts Institute Of Technology | Preparation of medical devices by solid free-form fabrication methods |
JP3488465B2 (ja) | 1993-10-28 | 2004-01-19 | ヒューストン・アドバンスド・リサーチ・センター | 結合反応を別々に検出する微細加工フロースルー多孔性装置 |
JP3247533B2 (ja) * | 1994-02-04 | 2002-01-15 | 本田技研工業株式会社 | 半導体ガスレートセンサの製造方法 |
US6129685A (en) * | 1994-02-09 | 2000-10-10 | The University Of Iowa Research Foundation | Stereotactic hypothalamic obesity probe |
US5798042A (en) | 1994-03-07 | 1998-08-25 | Regents Of The University Of California | Microfabricated filter with specially constructed channel walls, and containment well and capsule constructed with such filters |
US5770076A (en) | 1994-03-07 | 1998-06-23 | The Regents Of The University Of California | Micromachined capsules having porous membranes and bulk supports |
US5651900A (en) | 1994-03-07 | 1997-07-29 | The Regents Of The University Of California | Microfabricated particle filter |
US5985328A (en) | 1994-03-07 | 1999-11-16 | Regents Of The University Of California | Micromachined porous membranes with bulk support |
US5893974A (en) | 1994-03-07 | 1999-04-13 | Regents Of University Of California | Microfabricated capsules for immunological isolation of cell transplants |
US5660680A (en) | 1994-03-07 | 1997-08-26 | The Regents Of The University Of California | Method for fabrication of high vertical aspect ratio thin film structures |
US5971931A (en) * | 1994-03-29 | 1999-10-26 | Raff; Gilbert Lewis | Biologic micromonitoring methods and systems |
FR2719122B1 (fr) * | 1994-04-22 | 1996-07-12 | Scibiex Sarl | Dispositif et procédé d'analyse immunologique. |
US5947893A (en) | 1994-04-27 | 1999-09-07 | Board Of Regents, The University Of Texas System | Method of making a porous prothesis with biodegradable coatings |
DE69534640T2 (de) * | 1994-04-29 | 2006-08-10 | Scimed Life Systems, Inc., Maple Grove | Stent mit Kollagen |
US5837276A (en) * | 1994-09-02 | 1998-11-17 | Delab | Apparatus for the delivery of elongate solid drug compositions |
US5891108A (en) | 1994-09-12 | 1999-04-06 | Cordis Corporation | Drug delivery stent |
US6030917A (en) * | 1996-07-23 | 2000-02-29 | Symyx Technologies, Inc. | Combinatorial synthesis and analysis of organometallic compounds and catalysts |
US5585069A (en) | 1994-11-10 | 1996-12-17 | David Sarnoff Research Center, Inc. | Partitioned microelectronic and fluidic device array for clinical diagnostics and chemical synthesis |
US5707385A (en) | 1994-11-16 | 1998-01-13 | Advanced Cardiovascular Systems, Inc. | Drug loaded elastic membrane and method for delivery |
US5504026A (en) * | 1995-04-14 | 1996-04-02 | Analog Devices, Inc. | Methods for planarization and encapsulation of micromechanical devices in semiconductor processes |
CA2178541C (en) | 1995-06-07 | 2009-11-24 | Neal E. Fearnot | Implantable medical device |
US5609629A (en) | 1995-06-07 | 1997-03-11 | Med Institute, Inc. | Coated implantable medical device |
US5992769A (en) | 1995-06-09 | 1999-11-30 | The Regents Of The University Of Michigan | Microchannel system for fluid delivery |
US5713954A (en) * | 1995-06-13 | 1998-02-03 | Abiomed R&D, Inc. | Extra cardiac ventricular assist device |
SE9502258D0 (sv) | 1995-06-21 | 1995-06-21 | Pharmacia Biotech Ab | Method for the manufacture of a membrane-containing microstructure |
US5872010A (en) | 1995-07-21 | 1999-02-16 | Northeastern University | Microscale fluid handling system |
US5662689A (en) * | 1995-09-08 | 1997-09-02 | Medtronic, Inc. | Method and apparatus for alleviating cardioversion shock pain |
US6261584B1 (en) * | 1996-02-02 | 2001-07-17 | Alza Corporation | Sustained delivery of an active agent using an implantable system |
US6066163A (en) | 1996-02-02 | 2000-05-23 | John; Michael Sasha | Adaptive brain stimulation method and system |
US6051017A (en) * | 1996-02-20 | 2000-04-18 | Advanced Bionics Corporation | Implantable microstimulator and systems employing the same |
US5833603A (en) * | 1996-03-13 | 1998-11-10 | Lipomatrix, Inc. | Implantable biosensing transponder |
DE19610293C1 (de) * | 1996-03-15 | 1997-07-31 | Fraunhofer Ges Forschung | Vorrichtung zur gekapselten Aufnahme eines Materials |
US5951881A (en) | 1996-07-22 | 1999-09-14 | President And Fellows Of Harvard College | Fabrication of small-scale cylindrical articles |
US5817343A (en) * | 1996-05-14 | 1998-10-06 | Alkermes, Inc. | Method for fabricating polymer-based controlled-release devices |
US5769884A (en) | 1996-06-27 | 1998-06-23 | Cordis Corporation | Controlled porosity endovascular implant |
US5824204A (en) | 1996-06-27 | 1998-10-20 | Ic Sensors, Inc. | Micromachined capillary electrophoresis device |
US5797898A (en) * | 1996-07-02 | 1998-08-25 | Massachusetts Institute Of Technology | Microchip drug delivery devices |
US7070590B1 (en) * | 1996-07-02 | 2006-07-04 | Massachusetts Institute Of Technology | Microchip drug delivery devices |
US6136212A (en) | 1996-08-12 | 2000-10-24 | The Regents Of The University Of Michigan | Polymer-based micromachining for microfluidic devices |
US5792048A (en) | 1996-09-03 | 1998-08-11 | Schaefer; Guenter | Indentification pill with integrated microchip: smartpill, smartpill with integrated microchip and microprocessor for medical analyses and a smartpill, smartbox, smartplague, smartbadge or smartplate for luggage control on commercial airliners |
US6099561A (en) | 1996-10-21 | 2000-08-08 | Inflow Dynamics, Inc. | Vascular and endoluminal stents with improved coatings |
US6530951B1 (en) * | 1996-10-24 | 2003-03-11 | Cook Incorporated | Silver implantable medical device |
US6197013B1 (en) * | 1996-11-06 | 2001-03-06 | Setagon, Inc. | Method and apparatus for drug and gene delivery |
ZA9710342B (en) | 1996-11-25 | 1998-06-10 | Alza Corp | Directional drug delivery stent and method of use. |
IT1289815B1 (it) | 1996-12-30 | 1998-10-16 | Sorin Biomedica Cardio Spa | Stent per angioplastica e relativo procedimento di produzione |
EP0990142A4 (de) | 1996-12-31 | 2000-09-27 | Genometrix Genomics Inc | Molekulares multiplexanalyse verfahren und vorrichtung dazu |
US5782799A (en) * | 1997-02-07 | 1998-07-21 | Sarcos, Inc. | Method for automatic dosing of drugs |
US6056734A (en) * | 1997-02-07 | 2000-05-02 | Sarcos Lc | Method for automatic dosing of drugs |
US5938923A (en) | 1997-04-15 | 1999-08-17 | The Regents Of The University Of California | Microfabricated filter and capsule using a substrate sandwich |
US5843172A (en) | 1997-04-15 | 1998-12-01 | Advanced Cardiovascular Systems, Inc. | Porous medicated stent |
DE19716683C1 (de) * | 1997-04-21 | 1998-06-04 | Fraunhofer Ges Forschung | Vorrichtung zur getrennten, gekapselten Aufnahme einer Mehrzahl gleicher oder unterschiedlicher Stoffe |
US5976336A (en) | 1997-04-25 | 1999-11-02 | Caliper Technologies Corp. | Microfluidic devices incorporating improved channel geometries |
WO1998049548A1 (en) | 1997-04-25 | 1998-11-05 | Caliper Technologies Corporation | Microfluidic devices incorporating improved channel geometries |
US5879697A (en) | 1997-04-30 | 1999-03-09 | Schneider Usa Inc | Drug-releasing coatings for medical devices |
US5869004A (en) | 1997-06-09 | 1999-02-09 | Caliper Technologies Corp. | Methods and apparatus for in situ concentration and/or dilution of materials in microfluidic systems |
US5893640A (en) * | 1997-07-11 | 1999-04-13 | Hamilton Beach/Proctor-Silex, Inc. | Food mixer with removable splash guard |
IL121286A0 (en) | 1997-07-11 | 1998-01-04 | Pets N People Ltd | Apparatus and methods for dispensing pet care substances |
GB9715101D0 (en) | 1997-07-18 | 1997-09-24 | Environmental Sensors Ltd | The production of microstructures for analysis of fluids |
US5949187A (en) * | 1997-07-29 | 1999-09-07 | Motorola, Inc. | Organic electroluminescent device with plural microcavities |
DE19736520A1 (de) | 1997-08-22 | 1999-02-25 | Lohmann Therapie Syst Lts | Kennzeichnung für klebende flächenförmige dermale und transdermale therapeutische Darreichungsformen unter Verwendung eines klebenden Plfasters als Informationsträger, sowie Verfahren zu seiner Herstellung |
US5961492A (en) * | 1997-08-27 | 1999-10-05 | Science Incorporated | Fluid delivery device with temperature controlled energy source |
US5972027A (en) | 1997-09-30 | 1999-10-26 | Scimed Life Systems, Inc | Porous stent drug delivery system |
DE69828963T2 (de) | 1997-10-01 | 2006-01-26 | Medtronic AVE, Inc., Santa Rosa | Wirkstoffabgabe und Gentherapieabgabesystem |
US5842787A (en) | 1997-10-09 | 1998-12-01 | Caliper Technologies Corporation | Microfluidic systems incorporating varied channel dimensions |
US6081736A (en) * | 1997-10-20 | 2000-06-27 | Alfred E. Mann Foundation | Implantable enzyme-based monitoring systems adapted for long term use |
US6117643A (en) * | 1997-11-25 | 2000-09-12 | Ut Battelle, Llc | Bioluminescent bioreporter integrated circuit |
US5948227A (en) | 1997-12-17 | 1999-09-07 | Caliper Technologies Corp. | Methods and systems for performing electrophoretic molecular separations |
US6163720A (en) | 1997-12-18 | 2000-12-19 | Alza Corporation | Layered rate controlling membranes for use in an electrotransport device |
US6001090A (en) | 1998-02-09 | 1999-12-14 | Lenhart; Douglas | Thermal pharmaceutical delivery system |
US6251688B1 (en) * | 1998-03-20 | 2001-06-26 | Ia, Inc. | Method and apparatus for measurement of binding between a protein and a nucleotide |
US6241762B1 (en) * | 1998-03-30 | 2001-06-05 | Conor Medsystems, Inc. | Expandable medical device with ductile hinges |
US6027695A (en) | 1998-04-01 | 2000-02-22 | Dupont Pharmaceuticals Company | Apparatus for holding small volumes of liquids |
US6757560B1 (en) * | 1999-04-09 | 2004-06-29 | Novosis Pharma Ag | Transdermal delivery system (TDS) with electrode network |
DE19816143A1 (de) | 1998-04-09 | 1999-10-21 | Fischer Wilfried | Transdermales Applikationssystem (TDS) mit Elektrodenraster |
US6364856B1 (en) * | 1998-04-14 | 2002-04-02 | Boston Scientific Corporation | Medical device with sponge coating for controlled drug release |
EP1555036B1 (de) | 1998-04-27 | 2010-05-05 | Surmodics Inc. | Bioaktive Wirkstoffe freisetzende Beschichtungen |
US6161047A (en) | 1998-04-30 | 2000-12-12 | Medtronic Inc. | Apparatus and method for expanding a stimulation lead body in situ |
US6319241B1 (en) | 1998-04-30 | 2001-11-20 | Medtronic, Inc. | Techniques for positioning therapy delivery elements within a spinal cord or a brain |
US6503231B1 (en) * | 1998-06-10 | 2003-01-07 | Georgia Tech Research Corporation | Microneedle device for transport of molecules across tissue |
US6941171B2 (en) * | 1998-07-06 | 2005-09-06 | Advanced Bionics Corporation | Implantable stimulator methods for treatment of incontinence and pain |
US6908770B1 (en) * | 1998-07-16 | 2005-06-21 | Board Of Regents, The University Of Texas System | Fluid based analysis of multiple analytes by a sensor array |
US20020038146A1 (en) * | 1998-07-29 | 2002-03-28 | Ulf Harry | Expandable stent with relief cuts for carrying medicines and other materials |
US6201980B1 (en) | 1998-10-05 | 2001-03-13 | The Regents Of The University Of California | Implantable medical sensor system |
US6245104B1 (en) * | 1999-02-28 | 2001-06-12 | Inflow Dynamics Inc. | Method of fabricating a biocompatible stent |
DE19855421C2 (de) * | 1998-11-02 | 2001-09-20 | Alcove Surfaces Gmbh | Implantat |
FR2786564B1 (fr) * | 1998-11-27 | 2001-04-13 | Commissariat Energie Atomique | Capteur de pression a membrane comportant du carbure de silicium et procede de fabrication |
US6232150B1 (en) * | 1998-12-03 | 2001-05-15 | The Regents Of The University Of Michigan | Process for making microstructures and microstructures made thereby |
US6289237B1 (en) * | 1998-12-22 | 2001-09-11 | University Of Pittsburgh Of The Commonwealth System Of Higher Education | Apparatus for energizing a remote station and related method |
US6288888B1 (en) * | 1998-12-25 | 2001-09-11 | Nec Corporation | Electric double layer capacitor |
US6116458A (en) * | 1999-02-25 | 2000-09-12 | Dark; Richard C. G. | Sport drinking cup with valved straw cap |
US6171850B1 (en) | 1999-03-08 | 2001-01-09 | Caliper Technologies Corp. | Integrated devices and systems for performing temperature controlled reactions and analyses |
US6558422B1 (en) * | 1999-03-26 | 2003-05-06 | University Of Washington | Structures having coated indentations |
US6178349B1 (en) * | 1999-04-15 | 2001-01-23 | Medtronic, Inc. | Drug delivery neural stimulation device for treatment of cardiovascular disorders |
US6923784B2 (en) * | 1999-04-30 | 2005-08-02 | Medtronic, Inc. | Therapeutic treatment of disorders based on timing information |
US6096656A (en) | 1999-06-24 | 2000-08-01 | Sandia Corporation | Formation of microchannels from low-temperature plasma-deposited silicon oxynitride |
US6587719B1 (en) * | 1999-07-01 | 2003-07-01 | Cyberonics, Inc. | Treatment of obesity by bilateral vagus nerve stimulation |
US6804558B2 (en) * | 1999-07-07 | 2004-10-12 | Medtronic, Inc. | System and method of communicating between an implantable medical device and a remote computer system or health care provider |
US6334859B1 (en) * | 1999-07-26 | 2002-01-01 | Zuli Holdings Ltd. | Subcutaneous apparatus and subcutaneous method for treating bodily tissues with electricity or medicaments |
EP1210064B1 (de) * | 1999-08-18 | 2005-03-09 | Microchips, Inc. | Thermisch aktivierbarer microchip als abgabevorrichtung für chemikalien |
US6361522B1 (en) * | 1999-10-21 | 2002-03-26 | Cardiac Pacemakers, Inc. | Drug delivery system for implantable cardiac device |
AU770395B2 (en) * | 1999-11-17 | 2004-02-19 | Boston Scientific Limited | Microfabricated devices for the delivery of molecules into a carrier fluid |
GB9928270D0 (en) * | 1999-12-01 | 2000-01-26 | Eastman Kodak Co | Colour filter array film |
JP2003516343A (ja) * | 1999-12-10 | 2003-05-13 | マサチューセッツ インスティテュート オブ テクノロジー | 分子を送達するマイクロチップ素子およびその製作方法 |
US6401666B1 (en) * | 1999-12-27 | 2002-06-11 | Paul J. Kircher | Adjustable leash controlled strain reducing animal harness |
US6328699B1 (en) * | 2000-01-11 | 2001-12-11 | Cedars-Sinai Medical Center | Permanently implantable system and method for detecting, diagnosing and treating congestive heart failure |
US6384353B1 (en) * | 2000-02-01 | 2002-05-07 | Motorola, Inc. | Micro-electromechanical system device |
WO2001059447A1 (en) * | 2000-02-11 | 2001-08-16 | Yale University | Planar patch clamp electrodes |
EP1261427B1 (de) * | 2000-03-02 | 2011-03-02 | Microchips, Inc. | Mikromechanische geräte und verfahren zur speicherung und zur selektiven exposition von chemikalien |
US6379382B1 (en) * | 2000-03-13 | 2002-04-30 | Jun Yang | Stent having cover with drug delivery capability |
US20020007215A1 (en) * | 2000-05-19 | 2002-01-17 | Robert Falotico | Drug/drug delivery systems for the prevention and treatment of vascular disease |
WO2001091902A2 (en) * | 2000-05-30 | 2001-12-06 | Massachusetts Institute Of Technology | Methods and devices for sealing microchip reservoir devices |
US6395326B1 (en) * | 2000-05-31 | 2002-05-28 | Advanced Cardiovascular Systems, Inc. | Apparatus and method for depositing a coating onto a surface of a prosthesis |
US6367121B1 (en) * | 2000-06-19 | 2002-04-09 | Macmillan Donald M. | Adjustable length handle for flat finishers |
AU2001283358A1 (en) * | 2000-08-14 | 2002-02-25 | Pharmacia Corporation | Drug delivery system with burst electrode |
DE60116520T2 (de) * | 2000-10-10 | 2006-08-31 | Microchips, Inc., Bedford | Microchip-reservoir-vorrichtungen mit drahtloser übertragung von energie und daten |
WO2002030401A2 (en) * | 2000-10-11 | 2002-04-18 | Microchips, Inc. | Microchip reservoir devices and facilitated corrosion of electrodes |
WO2002034330A2 (en) * | 2000-10-26 | 2002-05-02 | Medtronic, Inc. | Method and apparatus to minimize the effects of a cardiac insult |
WO2002034327A2 (en) * | 2000-10-26 | 2002-05-02 | Medtronic, Inc. | Method and apparatus to minimize the effects of a cardiac insult |
EP1331965B1 (de) * | 2000-10-26 | 2008-07-16 | Medtronic, Inc. | Vorrichtung zur elektrischen stimulation des nervensystems zur therapie ventrikulärer fehlfunktionen, herzversagen und anderer kardialer zustände |
DE10061057A1 (de) * | 2000-12-08 | 2002-06-13 | Pharmed Holding Gmbh | Chip-Systeme zur kontrollierten Emission chemosensorisch wirkender Stoffe |
DE10063612C2 (de) | 2000-12-20 | 2002-11-07 | Fraunhofer Ges Forschung | Mikrosystem zur Kontrolle der Wirkstoffabgabe aus einem Wirkstoffreservoir sowie Implantat mit Mikrosystem |
US6666821B2 (en) | 2001-01-08 | 2003-12-23 | Medtronic, Inc. | Sensor system |
JP4657577B2 (ja) * | 2001-01-09 | 2011-03-23 | マイクロチップス・インコーポレーテッド | 眼への適用および他への適用のための可撓性マイクロチップデバイス |
AU2002245291A1 (en) | 2001-01-22 | 2002-07-30 | Integrated Sensing Systems, Inc. | Sensing catheter system and method of fabrication |
DE10102817B4 (de) | 2001-01-23 | 2006-01-12 | Lts Lohmann Therapie-Systeme Ag | Vorrichtung und Verfahren zur Hitzepulsgestützten transdermalen Applikation von Wirkstoffen |
US6571125B2 (en) * | 2001-02-12 | 2003-05-27 | Medtronic, Inc. | Drug delivery device |
US7338522B2 (en) * | 2001-02-13 | 2008-03-04 | Second Sight Medical Products, Inc. | Implantable retinal electrode array configuration for minimal retinal damage and method of reducing retinal stress |
US7181287B2 (en) * | 2001-02-13 | 2007-02-20 | Second Sight Medical Products, Inc. | Implantable drug delivery device |
US20020144548A1 (en) * | 2001-04-06 | 2002-10-10 | Cohn Michael B. | High precision accelerometer |
WO2002089767A1 (en) * | 2001-05-03 | 2002-11-14 | Massachusetts Eye And Ear Infirmary | Implantable drug delivery device and use thereof |
US6733485B1 (en) * | 2001-05-25 | 2004-05-11 | Advanced Bionics Corporation | Microstimulator-based electrochemotherapy methods and systems |
CA2447643A1 (en) | 2001-05-29 | 2002-12-05 | Medtronic, Inc. | Closed-loop neuromodulation for prevention and treatment of cardiac conditions |
WO2002096389A1 (en) * | 2001-05-30 | 2002-12-05 | Microchips, Inc. | Conformal coated microchip reservoir devices |
WO2002099457A1 (en) * | 2001-05-31 | 2002-12-12 | Massachusetts Inst Technology | Microchip devices with improved reservoir opening |
US6527938B2 (en) * | 2001-06-21 | 2003-03-04 | Syntheon, Llc | Method for microporous surface modification of implantable metallic medical articles |
CA2451953A1 (en) | 2001-06-28 | 2003-04-24 | Microchips, Inc. | Methods for hermetically sealing microchip reservoir devices |
WO2003002710A2 (en) * | 2001-06-29 | 2003-01-09 | The Board Of Trustees Of Leland Stanford Jr. University | Artificial synapse chip interface for electronic prosthetic retina |
US6663615B1 (en) | 2001-09-04 | 2003-12-16 | The Ohio State University | Dual stage microvalve and method of use |
US7025760B2 (en) * | 2001-09-07 | 2006-04-11 | Medtronic Minimed, Inc. | Method and system for non-vascular sensor implantation |
US7261713B2 (en) * | 2001-10-09 | 2007-08-28 | Synthes (Usa) | Adjustable fixator |
US7354597B2 (en) * | 2001-12-03 | 2008-04-08 | Massachusetts Institute Of Technology | Microscale lyophilization and drying methods for the stabilization of molecules |
US6893885B2 (en) * | 2002-01-18 | 2005-05-17 | The Regents Of The University Of Michigan | Method for electrically and mechanically connecting microstructures using solder |
EP1482914B1 (de) * | 2002-03-11 | 2015-04-22 | Novartis AG | Implantierbare arzneimittelabgabevorrichtung fürs auge |
EP1359215B1 (de) * | 2002-04-30 | 2010-03-10 | Societe Des Produits Nestle S.A. | Verwendung einer Soja Zelllinie mit hohem Isoflavon Gehalt |
EP1528940B1 (de) * | 2002-08-16 | 2011-04-13 | Microchips, Inc. | Vorrichtung mit kontrollierter abgabe und verfahren |
US7497855B2 (en) * | 2002-09-04 | 2009-03-03 | Microchips, Inc. | Method and device for the controlled delivery of parathyroid hormone |
US6878271B2 (en) * | 2002-09-09 | 2005-04-12 | Cytonome, Inc. | Implementation of microfluidic components in a microfluidic system |
AU2003278881A1 (en) * | 2002-09-23 | 2004-04-08 | Microchips, Inc. | Micro-reservoir osmotic release systems and microtube array device |
EP1551499A1 (de) * | 2002-10-04 | 2005-07-13 | Microchips, Inc. | Medizinische vorrichtung zur nervenstimulation und kontrollierten verabreichung von medikamenten |
EP1551505B1 (de) * | 2002-10-04 | 2010-02-24 | Microchips, Inc. | Medizinische vorrichtung zur gesteuerten arzneimittelverabreichung sowie herzüberwachung und/oder herzstimulation |
ATE494885T1 (de) * | 2003-04-25 | 2011-01-15 | Boston Scient Scimed Inc | Feste arzneimittelformulierung und vorrichtung zu ihrer aufbewahrung und kontrollierten abgabe |
WO2005010240A2 (en) * | 2003-07-17 | 2005-02-03 | Microchips, Inc. | Low temperature methods for hermetically sealing reservoir devices |
WO2005016558A2 (en) * | 2003-08-04 | 2005-02-24 | Microchips, Inc. | Methods for accelerated release of material from a reservoir device |
US7632234B2 (en) * | 2003-08-29 | 2009-12-15 | Medtronic, Inc. | Implantable biosensor devices for monitoring cardiac marker molecules |
US20050055080A1 (en) * | 2003-09-05 | 2005-03-10 | Naim Istephanous | Modulated stents and methods of making the stents |
CN1905835B (zh) * | 2003-09-11 | 2011-11-30 | 赛拉诺斯股份有限公司 | 分析物监测和药物递送的医疗装置 |
US6977434B2 (en) * | 2003-10-20 | 2005-12-20 | Hewlett-Packard Development Company, L.P. | Semiconductor assembly and spring member therefor |
JP4865195B2 (ja) * | 2004-04-27 | 2012-02-01 | キヤノン株式会社 | 流体素子 |
-
2001
- 2001-03-02 EP EP01926347A patent/EP1261427B1/de not_active Expired - Lifetime
- 2001-03-02 ES ES01926347T patent/ES2420279T3/es not_active Expired - Lifetime
- 2001-03-02 WO PCT/US2001/006886 patent/WO2001064344A2/en active IP Right Grant
- 2001-03-02 JP JP2001563234A patent/JP3960802B2/ja not_active Expired - Fee Related
- 2001-03-02 AU AU2001252890A patent/AU2001252890B2/en not_active Ceased
- 2001-03-02 AT AT01926347T patent/ATE499988T1/de not_active IP Right Cessation
- 2001-03-02 US US09/798,562 patent/US6551838B2/en not_active Expired - Lifetime
- 2001-03-02 DE DE60144142T patent/DE60144142D1/de not_active Expired - Lifetime
- 2001-03-02 CA CA002399842A patent/CA2399842C/en not_active Expired - Fee Related
- 2001-03-02 AU AU5289001A patent/AU5289001A/xx active Pending
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2002
- 2002-12-19 US US10/324,556 patent/US6849463B2/en not_active Expired - Lifetime
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- 2005-08-25 AU AU2005204238A patent/AU2005204238B2/en not_active Ceased
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- 2007-09-06 US US11/850,687 patent/US7410616B2/en not_active Expired - Fee Related
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2008
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US6849463B2 (en) | 2005-02-01 |
CA2399842C (en) | 2006-11-14 |
US20050124979A1 (en) | 2005-06-09 |
US20070299385A1 (en) | 2007-12-27 |
ATE499988T1 (de) | 2011-03-15 |
JP2003525432A (ja) | 2003-08-26 |
ES2420279T3 (es) | 2013-08-23 |
US20090018413A1 (en) | 2009-01-15 |
JP3960802B2 (ja) | 2007-08-15 |
US6551838B2 (en) | 2003-04-22 |
US8442611B2 (en) | 2013-05-14 |
JP2007248470A (ja) | 2007-09-27 |
US20030104590A1 (en) | 2003-06-05 |
US7648677B2 (en) | 2010-01-19 |
EP1261427A2 (de) | 2002-12-04 |
US20080115361A1 (en) | 2008-05-22 |
AU2005204238B2 (en) | 2007-05-31 |
US7445766B2 (en) | 2008-11-04 |
AU2005204238A1 (en) | 2005-09-15 |
EP1261427B1 (de) | 2011-03-02 |
AU2001252890B2 (en) | 2005-06-02 |
US7614135B2 (en) | 2009-11-10 |
US20060171888A1 (en) | 2006-08-03 |
WO2001064344A3 (en) | 2002-03-21 |
US7410616B2 (en) | 2008-08-12 |
WO2001064344A2 (en) | 2001-09-07 |
CA2399842A1 (en) | 2001-09-07 |
US20100137696A1 (en) | 2010-06-03 |
US20030049865A1 (en) | 2003-03-13 |
US20080115559A1 (en) | 2008-05-22 |
US7985386B2 (en) | 2011-07-26 |
AU5289001A (en) | 2001-09-12 |
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