DE60100858D1 - Prozess zur herstellung der kristallinen form i von cabergolin - Google Patents

Prozess zur herstellung der kristallinen form i von cabergolin

Info

Publication number: DE60100858D1
Authority: DE; Germany
Prior art keywords: cabergolin; preparation; crystalline form; crystalline
Prior art date: 2000-03-24
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Expired - Fee Related

Application number

DE60100858T

Other languages

English (en)

Other versions

DE60100858T2 (de

Inventor

Attilio Tomasi

Stefania Magenes

Mario Ungari

Giuliano Ramella

Gianfranco Pallanza

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Pfizer Italia SRL

Original Assignee

Pharmacia Italia SpA

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

2000-03-24

Filing date

2001-03-19

Publication date

2003-10-30

Family has litigation

First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=9888433&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60100858(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.

2001-03-19 Application filed by Pharmacia Italia SpA filed Critical Pharmacia Italia SpA

2003-10-30 Publication of DE60100858D1 publication Critical patent/DE60100858D1/de

2004-07-29 Application granted granted Critical

2004-07-29 Publication of DE60100858T2 publication Critical patent/DE60100858T2/de

2021-03-20 Anticipated expiration legal-status Critical

Status Expired - Fee Related legal-status Critical Current

Links

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- C07D457/06—Lysergic acid amides
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D457/00—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
- C07D457/04—Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/08—Bronchodilators
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/16—Masculine contraceptives
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/06—Antiglaucoma agents or miotics
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid

DE60100858T 2000-03-24 2001-03-19 Prozess zur herstellung der kristallinen form i von cabergolin Expired - Fee Related DE60100858T2 (de)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB0007308		2000-03-24
GBGB0007308.0A GB0007308D0 (en)	2000-03-24	2000-03-24	Process for preparing crystalline form \| of cabergoline
PCT/EP2001/003099 WO2001070740A1 (en)	2000-03-24	2001-03-19	Process for preparing crystalline form i of cabergoline

Publications (2)

Publication Number	Publication Date
DE60100858D1 true DE60100858D1 (de)	2003-10-30
DE60100858T2 DE60100858T2 (de)	2004-07-29

Family

ID=9888433

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
DE60100858T Expired - Fee Related DE60100858T2 (de)	2000-03-24	2001-03-19	Prozess zur herstellung der kristallinen form i von cabergolin

Country Status (31)

Country	Link
US (2)	US6727363B2 (de)
EP (1)	EP1272489B1 (de)
JP (1)	JP4184666B2 (de)
KR (1)	KR100827558B1 (de)
CN (1)	CN1188412C (de)
AR (1)	AR032449A1 (de)
AT (1)	ATE250601T1 (de)
AU (2)	AU780747B2 (de)
BR (1)	BR0109507A (de)
CA (1)	CA2402836A1 (de)
CZ (1)	CZ20023176A3 (de)
DE (1)	DE60100858T2 (de)
DK (1)	DK1272489T3 (de)
EA (1)	EA005928B1 (de)
EE (1)	EE05088B1 (de)
ES (1)	ES2208602T3 (de)
GB (1)	GB0007308D0 (de)
HK (1)	HK1052348B (de)
HU (1)	HUP0300591A3 (de)
IL (2)	IL150985A0 (de)
MX (1)	MXPA02009283A (de)
MY (1)	MY134189A (de)
NO (1)	NO20024321D0 (de)
NZ (1)	NZ521316A (de)
PE (1)	PE20011140A1 (de)
PL (1)	PL358253A1 (de)
PT (1)	PT1272489E (de)
SI (1)	SI1272489T1 (de)
SK (1)	SK13582002A3 (de)
WO (1)	WO2001070740A1 (de)
ZA (1)	ZA200206045B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
GB0007308D0 (en)	2000-03-24	2000-05-17	Pharmacia & Upjohn Spa	Process for preparing crystalline form \| of cabergoline
GB0007307D0 (en) *	2000-03-24	2000-05-17	Pharmacia & Upjohn Spa	Crystalline form \|\| of cabergoline
DE10043321B4 (de) *	2000-08-24	2005-07-28	Neurobiotec Gmbh	Verwendung eines transdermalen therapeutischen Systems zur Behandlung der Parkinsonschen Krankheit, zur Behandlung und Prävention des prämenstruellen Syndroms und zur Lactationshemmung
DE10053397A1 (de) *	2000-10-20	2002-05-02	Schering Ag	Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen
DE10064453A1 (de) *	2000-12-16	2002-07-04	Schering Ag	Verwendung eines dopaminergen Wirkstoffes zur Behandlung von dopaminerg behandelbaren Erkrankungen
AU2003224665A1 (en) *	2002-03-15	2003-09-29	Pharmacia Corporation	Process for preparing crystalline form i of cabergoline
WO2003078433A1 (en) *	2002-03-15	2003-09-25	Pharmacia Corporation	Process for preparing crystalline form i of cabergoline
IL155545A (en) *	2003-04-21	2009-12-24	Finetech Pharmaceutical Ltd	Solvate form of cabergoline
JP2007501274A (ja) *	2003-05-08	2007-01-25	イヴァックスファーマシューティカルズエス．アール．オー．	カベルゴリンの多形体
GB0409785D0 (en) *	2004-04-30	2004-06-09	Resolution Chemicals Ltd	Preparation of cabergoline
GB0505965D0 (en)	2005-03-23	2005-04-27	Resolution Chemicals Ltd	Preparation of cabergoline
GB0515430D0 (en) *	2005-07-27	2005-08-31	Resolution Chemicals Ltd	Preparation of cabergoline
US7339060B2 (en)	2005-03-23	2008-03-04	Resolution Chemicals, Ltd.	Preparation of cabergoline
EP1925616A1 (de) *	2006-10-26	2008-05-28	LEK Pharmaceuticals D.D.	Verfahren zur Herstellung kristalliner Formen des Cabergolins via stabile Solvate des Cabergolins
EP1953157A1 (de)	2007-01-31	2008-08-06	LEK Pharmaceuticals D.D.	Neue Kristallform von Cabergolin
EP2185169A2 (de) *	2007-08-29	2010-05-19	Max Zeller Söhne AG	Verwendung von extrakten von vitex agnus castus zur herstellung eines medikaments
EP4074552B1 (de) *	2021-04-16	2024-04-03	Thermo King LLC	Elektrische verbindungseinheit

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
DE3019322A1 (de)	1980-05-21	1981-12-03	Merck Patent Gmbh, 6100 Darmstadt	Psychopharmakon sowie verwendung von adenosinderivaten
US4526892A (en)	1981-03-03	1985-07-02	Farmitalia Carlo Erba, S.P.A.	Dimethylaminoalkyl-3-(ergoline-8'βcarbonyl)-ureas
GB2103603B (en)	1981-08-11	1985-04-11	Erba Farmitalia	Ergoline derivatives
GB9205439D0 (en)	1992-03-12	1992-04-22	Erba Carlo Spa	Process for the synthesis of ergoline derivatives
CA2146006C (en)	1993-08-18	2004-10-12	Louis Desantis, Jr.	Use of ergoline derivatives for the treatment of glaucoma
EP1075278A1 (de)	1998-01-13	2001-02-14	AstraZeneca UK Limited	Pharmazeutische zusammenstellungen die eine verbindung mit dopamin d2rezeptor agonistaktivität und eine verbindung (b) mit beta2-adrenergischer aktivität enthalten
ATE313326T1 (de)	1998-03-27	2006-01-15	Pharmacia & Upjohn Co Llc	VERWENDUNG VON CABERGOLIN ZUR BEHANDLUNG VON ßRESTLESS LEGS SYNDROMß
GB0007309D0 (en)	2000-03-24	2000-05-17	Pharmacia & Upjohn Spa	Crystalline form V\|\| of cabergoline
GB0007307D0 (en)	2000-03-24	2000-05-17	Pharmacia & Upjohn Spa	Crystalline form \|\| of cabergoline
GB0007308D0 (en) *	2000-03-24	2000-05-17	Pharmacia & Upjohn Spa	Process for preparing crystalline form \| of cabergoline

2000
- 2000-03-24 GB GBGB0007308.0A patent/GB0007308D0/en not_active Ceased
2001
- 2001-03-13 PE PE2001000237A patent/PE20011140A1/es not_active Application Discontinuation
- 2001-03-19 SI SI200130045T patent/SI1272489T1/xx unknown
- 2001-03-19 DK DK01936098T patent/DK1272489T3/da active
- 2001-03-19 AR ARP010101263A patent/AR032449A1/es unknown
- 2001-03-19 MX MXPA02009283A patent/MXPA02009283A/es active IP Right Grant
- 2001-03-19 HU HU0300591A patent/HUP0300591A3/hu unknown
- 2001-03-19 AU AU62110/01A patent/AU780747B2/en not_active Ceased
- 2001-03-19 IL IL15098501A patent/IL150985A0/xx active IP Right Grant
- 2001-03-19 BR BR0109507-2A patent/BR0109507A/pt not_active Application Discontinuation
- 2001-03-19 CZ CZ20023176A patent/CZ20023176A3/cs unknown
- 2001-03-19 EE EEP200200545A patent/EE05088B1/xx not_active IP Right Cessation
- 2001-03-19 PL PL01358253A patent/PL358253A1/xx not_active Application Discontinuation
- 2001-03-19 KR KR1020027012590A patent/KR100827558B1/ko not_active IP Right Cessation
- 2001-03-19 EP EP01936098A patent/EP1272489B1/de not_active Expired - Lifetime
- 2001-03-19 WO PCT/EP2001/003099 patent/WO2001070740A1/en active IP Right Grant
- 2001-03-19 CA CA002402836A patent/CA2402836A1/en not_active Withdrawn
- 2001-03-19 ES ES01936098T patent/ES2208602T3/es not_active Expired - Lifetime
- 2001-03-19 JP JP2001568941A patent/JP4184666B2/ja not_active Expired - Fee Related
- 2001-03-19 NZ NZ521316A patent/NZ521316A/en unknown
- 2001-03-19 EA EA200201016A patent/EA005928B1/ru unknown
- 2001-03-19 SK SK1358-2002A patent/SK13582002A3/sk unknown
- 2001-03-19 PT PT01936098T patent/PT1272489E/pt unknown
- 2001-03-19 AT AT01936098T patent/ATE250601T1/de not_active IP Right Cessation
- 2001-03-19 US US10/239,636 patent/US6727363B2/en not_active Expired - Fee Related
- 2001-03-19 CN CNB018070051A patent/CN1188412C/zh not_active Expired - Fee Related
- 2001-03-19 DE DE60100858T patent/DE60100858T2/de not_active Expired - Fee Related
- 2001-03-22 MY MYPI20011364A patent/MY134189A/en unknown
2002
- 2002-07-29 ZA ZA200206045A patent/ZA200206045B/xx unknown
- 2002-07-30 IL IL150985A patent/IL150985A/en not_active IP Right Cessation
- 2002-09-10 NO NO20024321A patent/NO20024321D0/no not_active Application Discontinuation
2003
- 2003-06-25 HK HK03104554.7A patent/HK1052348B/zh not_active IP Right Cessation
- 2003-10-31 US US10/698,737 patent/US6953854B2/en not_active Expired - Fee Related
2005
- 2005-07-14 AU AU2005203071A patent/AU2005203071B2/en not_active Ceased

Also Published As

Publication number	Publication date
HK1052348B (zh)	2005-09-16
EE05088B1 (et)	2008-10-15
ES2208602T3 (es)	2004-06-16
WO2001070740A1 (en)	2001-09-27
HK1052348A1 (en)	2003-09-11
AR032449A1 (es)	2003-11-12
IL150985A0 (en)	2003-02-12
MXPA02009283A (es)	2003-03-12
SK13582002A3 (sk)	2003-04-01
NO20024321L (no)	2002-09-10
BR0109507A (pt)	2002-12-10
CA2402836A1 (en)	2001-09-27
DK1272489T3 (da)	2003-12-15
AU2005203071B2 (en)	2007-10-18
PL358253A1 (en)	2004-08-09
EE200200545A (et)	2004-04-15
AU2005203071A1 (en)	2005-08-11
EA005928B1 (ru)	2005-08-25
SI1272489T1 (en)	2004-02-29
JP2003528100A (ja)	2003-09-24
AU6211001A (en)	2001-10-03
EA200201016A1 (ru)	2003-02-27
NO20024321D0 (no)	2002-09-10
PT1272489E (pt)	2004-02-27
AU780747B2 (en)	2005-04-14
JP4184666B2 (ja)	2008-11-19
CN1419554A (zh)	2003-05-21
NZ521316A (en)	2004-05-28
CN1188412C (zh)	2005-02-09
HUP0300591A2 (hu)	2003-07-28
ATE250601T1 (de)	2003-10-15
US20030149067A1 (en)	2003-08-07
US20040092744A1 (en)	2004-05-13
ZA200206045B (en)	2003-07-29
PE20011140A1 (es)	2001-11-01
IL150985A (en)	2007-03-08
EP1272489B1 (de)	2003-09-24
MY134189A (en)	2007-11-30
GB0007308D0 (en)	2000-05-17
US6727363B2 (en)	2004-04-27
HUP0300591A3 (en)	2009-01-28
KR100827558B1 (ko)	2008-05-07
US6953854B2 (en)	2005-10-11
KR20020081587A (ko)	2002-10-28
EP1272489A1 (de)	2003-01-08
CZ20023176A3 (cs)	2003-02-12
DE60100858T2 (de)	2004-07-29

Legal Events

Date	Code	Title	Description
2004-05-13	8327	Change in the person/name/address of the patent owner	Owner name: PHARMACIA ITALIA S.P.A., MAILAND/MILANO, IT
2004-10-21	8364	No opposition during term of opposition
2011-01-20	8339	Ceased/non-payment of the annual fee

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