DE60032337D1 - Lipasekatalysierte veresterung von fischoel - Google Patents

Lipasekatalysierte veresterung von fischoel

Info

Publication number
DE60032337D1
DE60032337D1 DE60032337T DE60032337T DE60032337D1 DE 60032337 D1 DE60032337 D1 DE 60032337D1 DE 60032337 T DE60032337 T DE 60032337T DE 60032337 T DE60032337 T DE 60032337T DE 60032337 D1 DE60032337 D1 DE 60032337D1
Authority
DE
Germany
Prior art keywords
fish oil
catalyzed esterification
lipase catalyzed
dha
free
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60032337T
Other languages
English (en)
Other versions
DE60032337T2 (de
Inventor
G Haraldsson
Olav Thorstad
Bjoern Kristinsson
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pronova Biopharma Norge AS
Original Assignee
Pronova Biocare AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pronova Biocare AS filed Critical Pronova Biocare AS
Application granted granted Critical
Publication of DE60032337D1 publication Critical patent/DE60032337D1/de
Publication of DE60032337T2 publication Critical patent/DE60032337T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6434—Docosahexenoic acids [DHA]
    • C—CHEMISTRY; METALLURGY
    • C11—ANIMAL OR VEGETABLE OILS, FATS, FATTY SUBSTANCES OR WAXES; FATTY ACIDS THEREFROM; DETERGENTS; CANDLES
    • C11C—FATTY ACIDS FROM FATS, OILS OR WAXES; CANDLES; FATS, OILS OR FATTY ACIDS BY CHEMICAL MODIFICATION OF FATS, OILS, OR FATTY ACIDS OBTAINED THEREFROM
    • C11C3/00—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom
    • C11C3/02—Fats, oils, or fatty acids by chemical modification of fats, oils, or fatty acids obtained therefrom by esterification of fatty acids with glycerol
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6409—Fatty acids
    • C12P7/6427—Polyunsaturated fatty acids [PUFA], i.e. having two or more double bonds in their backbone
    • C12P7/6432—Eicosapentaenoic acids [EPA]
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6458—Glycerides by transesterification, e.g. interesterification, ester interchange, alcoholysis or acidolysis
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/64—Fats; Fatty oils; Ester-type waxes; Higher fatty acids, i.e. having at least seven carbon atoms in an unbroken chain bound to a carboxyl group; Oxidised oils or fats
    • C12P7/6436—Fatty acid esters
    • C12P7/6445—Glycerides
    • C12P7/6472—Glycerides containing polyunsaturated fatty acid [PUFA] residues, i.e. having two or more double bonds in their backbone

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Fats And Perfumes (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE60032337T 1999-02-17 2000-02-16 Lipasekatalysierte veresterung von fischoelen Expired - Lifetime DE60032337T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NO990739 1999-02-17
NO19990739A NO312973B1 (no) 1999-02-17 1999-02-17 Lipase-katalysert forestring av marine oljer
PCT/NO2000/000056 WO2000049117A1 (en) 1999-02-17 2000-02-16 Lipase-catalysed esterification of marine oil

Publications (2)

Publication Number Publication Date
DE60032337D1 true DE60032337D1 (de) 2007-01-25
DE60032337T2 DE60032337T2 (de) 2007-07-12

Family

ID=19902972

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60032337T Expired - Lifetime DE60032337T2 (de) 1999-02-17 2000-02-16 Lipasekatalysierte veresterung von fischoelen

Country Status (12)

Country Link
US (1) US6518049B1 (de)
EP (1) EP1153114B1 (de)
JP (1) JP2002537442A (de)
AT (1) ATE348140T1 (de)
AU (1) AU757203B2 (de)
CA (1) CA2362212C (de)
DE (1) DE60032337T2 (de)
ES (1) ES2276669T3 (de)
NO (1) NO312973B1 (de)
NZ (1) NZ513574A (de)
WO (1) WO2000049117A1 (de)
ZA (1) ZA200106813B (de)

Families Citing this family (34)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002293774A (ja) * 2001-03-29 2002-10-09 Kuraray Co Ltd ５−（メタ）アクリロイルオキシ−２，６−ノルボルナンカルボラクトンの製造方法
EP2295529B2 (de) * 2002-07-11 2022-05-18 Basf As Verfahren zur Verminderung von Umweltschadstoffen in einem Öl oder einem Fett und Fischfutterprodukt
SE0202188D0 (sv) * 2002-07-11 2002-07-11 Pronova Biocare As A process for decreasing environmental pollutants in an oil or a fat, a volatile fat or oil environmental pollutants decreasing working fluid, a health supplement, and an animal feed product
NO319194B1 (no) * 2002-11-14 2005-06-27 Pronova Biocare As Lipase-katalysert forestringsfremgangsmate av marine oljer
WO2005084129A2 (en) * 2004-03-04 2005-09-15 Htl High-Tech Lipids Ltd. Structured triglycerides and emulsions comprising same
DE102004015781A1 (de) * 2004-03-31 2005-10-20 Cognis Ip Man Gmbh Verfahren zur enzymatischen Synthese von Triglyceriden ungesättigter Fettsäuren
US20060135610A1 (en) * 2004-12-22 2006-06-22 Bortz Jonathan D Cardiovascular compositions
CA2609341C (en) * 2005-05-23 2011-10-04 Natural Asa Concentration of fatty acid alkyl esters by enzymatic reactions with glycerol
ES2559959T3 (es) * 2005-06-16 2016-02-16 Dsm Nutritional Products Ag Enzimas inmovilizadas y métodos para usar las mismas
ES2292341B1 (es) * 2006-03-13 2009-03-16 Universidad De Almeria "procedimiento para la purificacion de acido eicosapentaenoico (epa)".
EP1978102B1 (de) * 2007-04-02 2010-07-07 Cognis IP Management GmbH Ein Gemisch enthaltend Fettsäureglyceride
EP1978101A1 (de) 2007-04-02 2008-10-08 Cognis IP Management GmbH Verfahren zur Anreicherung mehrfach ungesättigter Fettsäuren
JP2008278781A (ja) * 2007-05-09 2008-11-20 Osaka City ２位よりも１，３位のｄｈａ含有率が高いトリアシルグリセロールの製造方法
CL2008002020A1 (es) 2007-07-12 2008-11-14 Ocean Nutrition Canada Ltd Metodo de modificacion de un aceite, que comprende hidrolizar gliceridos con una solucion de lipasa thermomyces lanuginosus, separar la fraccion de acido graso saturado de la fraccion de glicerido hidrolizado y esterificar los gliceridos hidrolizados en la presencia de candida antarctica lipasa b; y composicion de aceite.
KR101357298B1 (ko) * 2008-06-20 2014-01-28 에이케이 앤 엠엔 바이오팜 주식회사 오메가-3계 고도불포화 지방산의 고순도 정제방법
DK2349250T3 (en) 2008-10-31 2017-07-03 Lipid Pharmaceuticals Ehf Fatty acids for use as a medicament
US8362080B2 (en) 2008-12-18 2013-01-29 Baylor College Of Medicine Increasing glutathione levels for therapy
WO2011067666A1 (en) 2009-12-03 2011-06-09 Blt Berg Lipidtech As Processes to generate compositions of enriched fatty acids
ES2862980T3 (es) 2009-12-30 2021-10-08 Basf Pharma Callanish Ltd Composiciones de ácido graso poliinsaturado obtenibles mediante un proceso de separación cromatográfica en lecho móvil simulado
WO2012095749A1 (en) 2011-01-14 2012-07-19 Pharma Marine As Removal of monoglycerides from fatty acid concentrates
GB201111595D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Improved process
GB201111594D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New improved process
GB201111591D0 (en) 2011-07-06 2011-08-24 Equateq Ltd Further new process
GB201111589D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New modified process
GB201111601D0 (en) 2011-07-06 2011-08-24 Equateq Ltd New process
WO2013035113A1 (en) 2011-09-06 2013-03-14 Lipid Pharmaceuticals Ehf. Coated suppositories
SI2800563T1 (sl) 2012-01-06 2018-11-30 Omthera Pharmaceuticals Inc. Z DPA obogateni sestavki omega-3 polinenasičenih maščobnih kislin v obliki proste kisline
EP2846779A4 (de) 2012-05-07 2015-12-16 Omthera Pharmaceuticals Inc Zusammensetzungen aus statinen und omega-3-fettsäuren
GB201300354D0 (en) 2013-01-09 2013-02-20 Basf Pharma Callanish Ltd Multi-step separation process
US8802880B1 (en) 2013-05-07 2014-08-12 Group Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
US9428711B2 (en) 2013-05-07 2016-08-30 Groupe Novasep Chromatographic process for the production of highly purified polyunsaturated fatty acids
EP3118186B1 (de) 2013-12-11 2022-02-09 Novasep Process Chromatografische anlage zur herstellung von mehrfach ungesättigten fettsäuren
US10975031B2 (en) 2014-01-07 2021-04-13 Novasep Process Method for purifying aromatic amino acids
US10722542B2 (en) 2016-06-16 2020-07-28 Ambo Innovations, Llc Non-winterized, standardized marine source oil products and methods of making thereof

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH02303492A (ja) 1989-05-19 1990-12-17 Nippon Oil & Fats Co Ltd 長鎖高度不飽和脂肪酸グリセリドの濃縮法
DK95490D0 (da) * 1990-04-18 1990-04-18 Novo Nordisk As Fremgangsmaade til fremstilling af triglycerid og triglyceridsammensaetning
JPH07203979A (ja) 1994-01-25 1995-08-08 Maruha Corp 高度不飽和脂肪酸グリセリドの製造方法
GB9404483D0 (en) * 1994-03-08 1994-04-20 Norsk Hydro As Refining marine oil compositions
WO1996037586A1 (en) * 1995-05-24 1996-11-28 Loders Croklaan B.V. Production method for fats with long chain polyunsaturated fatty acids
AU6610996A (en) * 1995-05-24 1996-12-11 Loders Croklaan B.V. Production of materials high in long chain polyunsaturated f atty acids
WO1998018952A1 (fr) 1996-10-30 1998-05-07 Nippon Suisan Kaisha, Ltd. Procede de production de matieres grasses contenant des acides gras hautement insatures contenant eux-memes un acide docosahexaenoique a concentration selective

Also Published As

Publication number Publication date
JP2002537442A (ja) 2002-11-05
ES2276669T3 (es) 2007-07-01
NZ513574A (en) 2002-12-20
EP1153114B1 (de) 2006-12-13
CA2362212A1 (en) 2000-08-24
AU757203B2 (en) 2003-02-06
NO990739D0 (no) 1999-02-17
NO312973B1 (no) 2002-07-22
EP1153114A1 (de) 2001-11-14
NO990739L (no) 2000-08-18
CA2362212C (en) 2009-10-27
DE60032337T2 (de) 2007-07-12
ATE348140T1 (de) 2007-01-15
AU2833800A (en) 2000-09-04
WO2000049117A1 (en) 2000-08-24
US6518049B1 (en) 2003-02-11
ZA200106813B (en) 2002-08-19

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Legal Events

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