DE60027564D1 - Tek-antagonisten - Google Patents

Tek-antagonisten

Info

Publication number
DE60027564D1
DE60027564D1 DE60027564T DE60027564T DE60027564D1 DE 60027564 D1 DE60027564 D1 DE 60027564D1 DE 60027564 T DE60027564 T DE 60027564T DE 60027564 T DE60027564 T DE 60027564T DE 60027564 D1 DE60027564 D1 DE 60027564D1
Authority
DE
Germany
Prior art keywords
tek antagonists
methods
tek
antagonists
angiogenesis
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE60027564T
Other languages
English (en)
Other versions
DE60027564T3 (de
DE60027564T2 (de
Inventor
P Cerretti
G Borges
C Fanslow
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Immunex Corp
Original Assignee
Immunex Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=22479496&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE60027564(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Immunex Corp filed Critical Immunex Corp
Publication of DE60027564D1 publication Critical patent/DE60027564D1/de
Application granted granted Critical
Publication of DE60027564T2 publication Critical patent/DE60027564T2/de
Publication of DE60027564T3 publication Critical patent/DE60027564T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/71Receptors; Cell surface antigens; Cell surface determinants for growth factors; for growth regulators
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00Drugs for disorders of the senses
    • A61P27/02Ophthalmic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Toxicology (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Veterinary Medicine (AREA)
  • Cell Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Ophthalmology & Optometry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DE60027564T 1999-06-07 2000-06-07 Tek-antagonisten Expired - Lifetime DE60027564T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US13788999P 1999-06-07 1999-06-07
US137889P 1999-06-07
PCT/US2000/015706 WO2000075323A1 (en) 1999-06-07 2000-06-07 Tek antagonists

Publications (3)

Publication Number Publication Date
DE60027564D1 true DE60027564D1 (de) 2006-06-01
DE60027564T2 DE60027564T2 (de) 2007-05-10
DE60027564T3 DE60027564T3 (de) 2009-07-23

Family

ID=22479496

Family Applications (1)

Application Number Title Priority Date Filing Date
DE60027564T Expired - Lifetime DE60027564T3 (de) 1999-06-07 2000-06-07 Tek-antagonisten

Country Status (14)

Country Link
US (2) US6413932B1 (de)
EP (1) EP1187918B9 (de)
JP (1) JP4587626B2 (de)
AT (1) ATE324444T1 (de)
AU (1) AU783960B2 (de)
CA (1) CA2374851A1 (de)
CY (1) CY1105078T1 (de)
DE (1) DE60027564T3 (de)
DK (1) DK1187918T4 (de)
ES (1) ES2262518T5 (de)
IL (2) IL146482A0 (de)
NZ (1) NZ516258A (de)
PT (1) PT1187918E (de)
WO (1) WO2000075323A1 (de)

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* Cited by examiner, † Cited by third party
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US7205275B2 (en) 2001-10-11 2007-04-17 Amgen Inc. Methods of treatment using specific binding agents of human angiopoietin-2
US7521053B2 (en) 2001-10-11 2009-04-21 Amgen Inc. Angiopoietin-2 specific binding agents
US7138370B2 (en) * 2001-10-11 2006-11-21 Amgen Inc. Specific binding agents of human angiopoietin-2
US7658924B2 (en) 2001-10-11 2010-02-09 Amgen Inc. Angiopoietin-2 specific binding agents
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WO2005113596A2 (en) * 2004-05-14 2005-12-01 Receptor Biologix, Inc. Cell surface receptor isoforms and methods of identifying and using the same
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US7507748B2 (en) * 2004-07-22 2009-03-24 Amgen Inc. Substituted aryl-amine derivatives and methods of use
US20080119367A1 (en) * 2004-12-17 2008-05-22 Mayo Foundation For Medical Education And Research Prognosis of Renal Cell Carcinoma
US7973140B2 (en) * 2004-12-21 2011-07-05 Medimmune Limited Antibodies directed to angiopoietin-2 and uses thereof
US20090170769A1 (en) * 2005-05-13 2009-07-02 Pei Jin Cell surface receptor isoforms and methods of identifying and using the same
AR059066A1 (es) 2006-01-27 2008-03-12 Amgen Inc Combinaciones del inhibidor de la angiopoyetina -2 (ang2) y el inhibidor del factor de crecimiento endotelial vascular (vegf)
PE20080403A1 (es) 2006-07-14 2008-04-25 Amgen Inc Derivados heterociclicos fusionados y metodos de uso
US8217177B2 (en) 2006-07-14 2012-07-10 Amgen Inc. Fused heterocyclic derivatives and methods of use
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US8454960B2 (en) 2008-01-03 2013-06-04 The Scripps Research Institute Multispecific antibody targeting and multivalency through modular recognition domains
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US8574577B2 (en) 2008-01-03 2013-11-05 The Scripps Research Institute VEGF antibodies comprising modular recognition domains
US8557242B2 (en) 2008-01-03 2013-10-15 The Scripps Research Institute ERBB2 antibodies comprising modular recognition domains
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US9745288B2 (en) 2011-08-16 2017-08-29 Indiana University Research And Technology Corporation Compounds and methods for treating cancer by inhibiting the urokinase receptor
EP3415533A1 (de) * 2011-08-19 2018-12-19 Regeneron Pharmaceuticals, Inc. Anti-tie2-antikörper und verwendungen davon
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BR112015023752B1 (pt) 2013-03-15 2023-11-14 Zyngenia, Inc. Domínio de reconhecimento modular (mrd), complexo compreendendo mrd e cetuximabe, usos do complexo para inibir a angiogênese e tratar câncer e composição farmacêutica compreendendo o dito complexo
TW201605896A (zh) 2013-08-30 2016-02-16 安美基股份有限公司 Gitr抗原結合蛋白
CN109069639B (zh) 2016-03-08 2022-07-08 詹森生物科技公司 Gitr抗体、方法及用途
UA124474C2 (uk) 2016-12-22 2021-09-22 Емджен Інк. БЕНЗІЗОТІАЗОЛЬНІ, ІЗОТІАЗОЛО[3,4-b]ПІРИДИНОВІ, ХІНАЗОЛІНОВІ, ФТАЛАЗИНОВІ, ПІРИДО[2,3-d]ПІРИДАЗИНОВІ Й ПІРИДО[2,3-d]ПІРИМІДИНОВІ ПОХІДНІ ЯК ІНГІБІТОРИ G12C KRAS ДЛЯ ЛІКУВАННЯ РАКУ ЛЕГЕНІ, РАКУ ПІДШЛУНКОВОЇ ЗАЛОЗИ АБО КОЛОРЕКТАЛЬНОГО РАКУ
JOP20190272A1 (ar) 2017-05-22 2019-11-21 Amgen Inc مثبطات kras g12c وطرق لاستخدامها
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JP7516029B2 (ja) 2018-11-16 2024-07-16 アムジエン・インコーポレーテツド Kras g12c阻害剤化合物の重要な中間体の改良合成法
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Also Published As

Publication number Publication date
WO2000075323A1 (en) 2000-12-14
NZ516258A (en) 2004-02-27
EP1187918A1 (de) 2002-03-20
JP2003501090A (ja) 2003-01-14
IL146482A (en) 2010-11-30
DE60027564T3 (de) 2009-07-23
AU5328200A (en) 2000-12-28
EP1187918B9 (de) 2009-08-19
ES2262518T3 (es) 2006-12-01
IL146482A0 (en) 2002-07-25
EP1187918B1 (de) 2006-04-26
CY1105078T1 (el) 2009-11-04
ES2262518T5 (es) 2009-05-08
US20070025993A1 (en) 2007-02-01
DE60027564T2 (de) 2007-05-10
PT1187918E (pt) 2006-08-31
DK1187918T3 (da) 2006-08-21
US6413932B1 (en) 2002-07-02
CA2374851A1 (en) 2000-12-14
ATE324444T1 (de) 2006-05-15
AU783960B2 (en) 2006-01-05
DK1187918T4 (da) 2009-02-23
JP4587626B2 (ja) 2010-11-24
EP1187918B2 (de) 2009-01-14

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