CY1107074T1 - Συνθεση εναντιομερων 4-αμινο-θαλιδομιδης - Google Patents

Συνθεση εναντιομερων 4-αμινο-θαλιδομιδης

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Publication number
CY1107074T1
CY1107074T1 CY20071101557T CY071101557T CY1107074T1 CY 1107074 T1 CY1107074 T1 CY 1107074T1 CY 20071101557 T CY20071101557 T CY 20071101557T CY 071101557 T CY071101557 T CY 071101557T CY 1107074 T1 CY1107074 T1 CY 1107074T1
Authority
CY
Cyprus
Prior art keywords
amino
thalidomidis
antiometer
composition
thalidomide
Prior art date
Application number
CY20071101557T
Other languages
English (en)
Inventor
Anthony Treston
Jamshed H Shah
Robert J D'amato
Kimberly A Hunsucker
John Rougas
Barry P Conner
Victor Pribluda
Glenn M Swartz
Original Assignee
The Children΄S Medical Center Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by The Children΄S Medical Center Corporation filed Critical The Children΄S Medical Center Corporation
Publication of CY1107074T1 publication Critical patent/CY1107074T1/el

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/454—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. pimozide, domperidone
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    • A61P31/12—Antivirals
    • A61P31/20—Antivirals for DNA viruses
    • A61P31/22—Antivirals for DNA viruses for herpes viruses
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    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Abstract

Η εφεύρεση παρέχει νέα και χρήσιμα ανάλογα της 4-αμινο-θαλιδομίδης. Αυτά τα ανάλογα περιλαμβάνουν S(-)-3-αμινο-θαλιδομίδη και R(+)-3-αμινο-θαλιδομίδη. Η εφεύρεση επίσης παρέχει μεθόδους για κατασκευή αυτών των αναλόγων. Περαιτέρω, η εφεύρεση παρέχει μεθόδους για αναστολή αγγειογένεσης και θεραπεία ασθενειών που συνδυάζονται με αγγειογένεση, συμπεριλαμβανομένου καρκίνου και εκφυλισμού κηλίδας, με χορήγηση αυτών των ενώσεων.
CY20071101557T 2000-11-30 2007-12-06 Συνθεση εναντιομερων 4-αμινο-θαλιδομιδης CY1107074T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US25021900P 2000-11-30 2000-11-30
EP01270117A EP1353672B1 (en) 2000-11-30 2001-11-30 Synthesis of 4-amino-thalidomide enantiomers

Publications (1)

Publication Number Publication Date
CY1107074T1 true CY1107074T1 (el) 2012-10-24

Family

ID=22946815

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071101557T CY1107074T1 (el) 2000-11-30 2007-12-06 Συνθεση εναντιομερων 4-αμινο-θαλιδομιδης

Country Status (15)

Country Link
US (3) US7812169B2 (el)
EP (1) EP1353672B1 (el)
JP (2) JP4242651B2 (el)
AT (1) ATE374609T1 (el)
AU (2) AU2002253795B2 (el)
CA (1) CA2430669C (el)
CY (1) CY1107074T1 (el)
DE (1) DE60130799T2 (el)
DK (1) DK1353672T3 (el)
ES (1) ES2290091T3 (el)
HK (1) HK1061354A1 (el)
MX (1) MXPA03004699A (el)
NZ (1) NZ526683A (el)
PT (1) PT1353672E (el)
WO (1) WO2002064083A2 (el)

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