DE3886221D1 - VERFAHREN ZUR HERSTELLUNG VON PROTEINPRODUKTEN IN -i(ASPERGILLUS) UND PROMOTOREN ZUR VERWENDUNG IN -i(ASPERGILLUS). - Google Patents

VERFAHREN ZUR HERSTELLUNG VON PROTEINPRODUKTEN IN -i(ASPERGILLUS) UND PROMOTOREN ZUR VERWENDUNG IN -i(ASPERGILLUS).

Info

Publication number
DE3886221D1
DE3886221D1 DE88908169T DE3886221T DE3886221D1 DE 3886221 D1 DE3886221 D1 DE 3886221D1 DE 88908169 T DE88908169 T DE 88908169T DE 3886221 T DE3886221 T DE 3886221T DE 3886221 D1 DE3886221 D1 DE 3886221D1
Authority
DE
Germany
Prior art keywords
aspergillus
promotors
protein products
producing protein
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE88908169T
Other languages
English (en)
Other versions
DE3886221T3 (de
DE3886221T2 (de
Inventor
Helle Woeldike
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novozymes AS
Original Assignee
Novo Nordisk AS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26067550&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE3886221(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from DK460987A external-priority patent/DK460987D0/da
Priority claimed from DK512687A external-priority patent/DK512687D0/da
Application filed by Novo Nordisk AS filed Critical Novo Nordisk AS
Publication of DE3886221D1 publication Critical patent/DE3886221D1/de
Application granted granted Critical
Publication of DE3886221T2 publication Critical patent/DE3886221T2/de
Publication of DE3886221T3 publication Critical patent/DE3886221T3/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/24Hydrolases (3) acting on glycosyl compounds (3.2)
    • C12N9/2402Hydrolases (3) acting on glycosyl compounds (3.2) hydrolysing O- and S- glycosyl compounds (3.2.1)
    • C12N9/2405Glucanases
    • C12N9/2408Glucanases acting on alpha -1,4-glucosidic bonds
    • C12N9/2411Amylases
    • C12N9/2414Alpha-amylase (3.2.1.1.)
    • C12N9/2417Alpha-amylase (3.2.1.1.) from microbiological source
    • C12N9/242Fungal source
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/58Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi
    • C12N9/62Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from fungi from Aspergillus
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • C07K2319/01Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02Fusion polypeptide containing a localisation/targetting motif containing a signal sequence

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Mycology (AREA)
  • Medicinal Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE3886221T 1987-09-04 1988-09-02 VERFAHREN ZUR HERSTELLUNG VON PROTEINPRODUKTEN IN -i(ASPERGILLUS) UND PROMOTOREN ZUR VERWENDUNG IN -i(ASPERGILLUS). Expired - Lifetime DE3886221T3 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
DK460987A DK460987D0 (da) 1987-09-04 1987-09-04 Fremstilling af proteiner.
DK512687A DK512687D0 (da) 1987-09-29 1987-09-29 Fremstilling af proteiner
PCT/DK1988/000145 WO1989001969A1 (en) 1987-09-04 1988-09-02 Process for the production of protein products in aspergillus and promoters for use in aspergillus

Publications (3)

Publication Number Publication Date
DE3886221D1 true DE3886221D1 (de) 1994-01-20
DE3886221T2 DE3886221T2 (de) 1994-05-19
DE3886221T3 DE3886221T3 (de) 2000-12-21

Family

ID=26067550

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3886221T Expired - Lifetime DE3886221T3 (de) 1987-09-04 1988-09-02 VERFAHREN ZUR HERSTELLUNG VON PROTEINPRODUKTEN IN -i(ASPERGILLUS) UND PROMOTOREN ZUR VERWENDUNG IN -i(ASPERGILLUS).

Country Status (4)

Country Link
EP (1) EP0383779B2 (de)
JP (1) JP2703598B2 (de)
DE (1) DE3886221T3 (de)
WO (1) WO1989001969A1 (de)

Families Citing this family (94)

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US5766912A (en) * 1986-03-17 1998-06-16 Novo Nordisk A/S Humicola lipase produced in aspergillus
US5536661A (en) * 1987-03-10 1996-07-16 Novo Nordisk A/S Process for the production of protein products in aspergillus
CA1341226C (en) * 1988-08-16 2001-05-01 Wim Van Hartingsveldt Gene replacement as a tool for the construction of aspergillus strains
US5766939A (en) * 1989-05-05 1998-06-16 Baylor College Of Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using CDNA sequences in various organisms
IL94183A (en) 1989-05-05 2003-09-17 Baylor College Medicine cDNA SEQUENCE CODING FOR HUMAN LACTOFERRIN PROTEIN OR PORTION THEREOF AND LACTOFERRIN PROTEIN PRODUCED FROM SAID SEQUENCE
US5849881A (en) * 1989-05-05 1998-12-15 Baylor College Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using cDNA sequences in various organisms
US6100054A (en) * 1989-05-05 2000-08-08 Baylor College Of Medicine Production for recombinant lactoferrin and lactoferrin polypeptides using DNA sequences in various organisms
US5571691A (en) * 1989-05-05 1996-11-05 Baylor College Of Medicine Production of recombinant lactoferrin and lactoferrin polypeptides using CDNA sequences in various organisms
WO1991013971A1 (en) * 1990-03-13 1991-09-19 Hawaii Biotechnology Group, Inc. Neurospora expression system
FR2666590A1 (fr) * 1990-09-11 1992-03-13 Sanofi Sa Adn recombinant codant pour un precurseur de l'endothiapepsine, vecteur d'expression, bacteries et cellules eucaryotes transformees.
EP0585285B1 (de) 1991-05-01 1998-08-12 Novo Nordisk A/S Stabilisierte enzyme
ZA932568B (en) * 1992-04-24 1993-11-12 Baylor College Midecine A Non Production of recombinant human lactoferrin
WO1995000652A1 (en) * 1993-06-18 1995-01-05 Ciba-Geigy Ag Chimeric plant genes possessing independent regulatory sequences
GB9316883D0 (en) * 1993-08-13 1993-09-29 Univ Leeds Production of heterologous peptices
US7816129B2 (en) 1994-07-29 2010-10-19 Ab Enzymes Gmbh Production and secretion of proteins of bacterial origin in filamentous fungi
US6300114B1 (en) * 1994-07-29 2001-10-09 Rohm Enzyme Finland Oy Sequences of xylanase and xylanase expression vectors
US5935836A (en) * 1994-07-29 1999-08-10 Rohm Enzyme Finland Oy Actinomadura xylanase sequences and methods of use
US6111081A (en) * 1996-05-31 2000-08-29 Baylor College Of Medicine Lactoferrin variants and uses thereof
GB9704157D0 (en) * 1997-02-28 1997-04-16 Danisco Expression element
AU7398100A (en) * 1999-09-13 2001-04-17 Concordia University A multifunctional system for the efficient manipulation of protein expression infilamentous fungi and method using same
WO2001034784A1 (en) 1999-11-10 2001-05-17 Novozymes A/S Fungamyl-like alpha-amylase variants
EP1373493B1 (de) 2001-03-22 2013-07-31 Novo Nordisk Health Care AG Derivat des koagulationsfaktors vii
US7063962B2 (en) 2001-07-20 2006-06-20 Novozymes A/S DNA sequences for regulating transcription
ATE532858T1 (de) 2001-09-27 2011-11-15 Novo Nordisk Healthcare Ag Menschliche gerinnungsfaktor-vii-polypeptide
US20050170350A1 (en) * 2002-02-16 2005-08-04 Stringer Mary A. Expression cloning methods in filamentous fungi
CN100506997C (zh) 2003-05-30 2009-07-01 诺维信公司 酒精产品生产方法
ES2425351T3 (es) 2003-06-25 2013-10-14 Novozymes A/S Polipéptidos que tienen actividad de alfa-amilasa y polinucleótidos que codifican los mismos
MXPA06000212A (es) 2003-06-25 2006-03-21 Novozymes As Enzimas para procesar almidon.
ES2381110T3 (es) 2003-09-09 2012-05-23 Novo Nordisk Health Care Ag Polipéptidos de factor VII de coagulación
ES2543131T3 (es) 2004-12-22 2015-08-14 Novozymes North America, Inc. Enzimas para tratamiento de almidón
EP1856263A1 (de) * 2005-03-01 2007-11-21 DSMIP Assets B.V. Aspergillus-promotoren zur expression eines gens in einer pilzzelle
JP5690047B2 (ja) 2005-09-14 2015-03-25 ノボ ノルディスク ヘルス ケア アーゲー ヒト凝固第vii因子ポリペプチド
EP1941049A4 (de) 2005-09-20 2011-12-21 Novozymes North America Inc Verfahren zur herstellung eines gärungsproduktes
US8071089B2 (en) 2005-11-01 2011-12-06 Bio-Cat, Inc. Composition with a fungal (yeast) lipase and method for treating lipid malabsorption in cystic fibrosis as well as people suffering from pancreatic lipase insufficiency
US20080318284A1 (en) 2005-12-22 2008-12-25 Novozymes North America, Inc. Processes for Producing a Fermentation Product
CN101405397A (zh) 2006-03-22 2009-04-08 诺维信北美公司 发酵方法
WO2007149699A2 (en) 2006-06-21 2007-12-27 Novozymes North America, Inc. Desizing and scouring process
US10023881B2 (en) 2007-04-24 2018-07-17 Novozymes A/S Detoxifying pre-treated lignocellulose-containing materials
JP5497632B2 (ja) 2007-05-09 2014-05-21 ノボザイムス アクティーゼルスカブ 関心対象のポリペプチドを産生するライブラリークローンの選択に適した発現クローニング法
ES2425596T3 (es) 2007-09-03 2013-10-16 Novozymes A/S Detoxificación y reciclaje de soluciones de lavado utilizadas en el pretratamiento de materiales con contenido de lignocelulosa
EP2364363A2 (de) 2008-06-23 2011-09-14 Novozymes A/S Verfahren zur herstellung von gärungsprodukten
DK2344650T3 (da) 2008-09-30 2014-07-14 Novozymes North America Inc Forbedring af enzymatisk hydrolyse af forbehandlet lignocelluloseholdigt materiale med distillers dried grain med solubles (ddg/s)
WO2010059413A2 (en) 2008-11-20 2010-05-27 Novozymes, Inc. Polypeptides having amylolytic enhancing activity and polynucleotides encoding same
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WO2010078392A2 (en) 2008-12-31 2010-07-08 Novozymes North America, Inc. Processes of producing fermentation products
CA2766720A1 (en) 2009-07-07 2011-01-13 Novozymes A/S Process for treating a substrate with an enzyme
DK2454590T3 (en) 2009-07-17 2016-12-05 Novozymes As A method of analysis of cellulose degradation by hydrolysis of the cellulose-containing material
KR102184713B1 (ko) 2009-07-17 2020-12-01 오메로스 코포레이션 보체 활성화의 억제제로서의 masp 이소형
CN102665425A (zh) 2009-09-30 2012-09-12 诺维信公司 馒头制备方法和馒头改进组合物
WO2011066576A1 (en) 2009-11-30 2011-06-03 Novozymes A/S Polypeptides having glucoamylase activity and polynucleotides encoding same
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EP3526336A1 (de) 2016-10-17 2019-08-21 Novozymes A/S Verfahren zur schaumreduzierung während der ethanolfermentation
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Also Published As

Publication number Publication date
EP0383779B2 (de) 2000-05-31
EP0383779A1 (de) 1990-08-29
JPH04503150A (ja) 1992-06-11
WO1989001969A1 (en) 1989-03-09
EP0383779B1 (de) 1993-12-08
DE3886221T3 (de) 2000-12-21
DE3886221T2 (de) 1994-05-19
JP2703598B2 (ja) 1998-01-26

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Owner name: NOVOZYMES A/S, BAGSVAERD, DK