DE3685626D1 - Sequenzierung von peptiden. - Google Patents

Sequenzierung von peptiden.

Info

Publication number
DE3685626D1
DE3685626D1 DE8686307356T DE3685626T DE3685626D1 DE 3685626 D1 DE3685626 D1 DE 3685626D1 DE 8686307356 T DE8686307356 T DE 8686307356T DE 3685626 T DE3685626 T DE 3685626T DE 3685626 D1 DE3685626 D1 DE 3685626D1
Authority
DE
Germany
Prior art keywords
sequencing
peptides
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8686307356T
Other languages
English (en)
Other versions
DE3685626T2 (de
Inventor
David Harry Hawke
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Beckman Research Institute of City of Hope
Original Assignee
Beckman Research Institute of City of Hope
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Beckman Research Institute of City of Hope filed Critical Beckman Research Institute of City of Hope
Publication of DE3685626D1 publication Critical patent/DE3685626D1/de
Application granted granted Critical
Publication of DE3685626T2 publication Critical patent/DE3685626T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C07K1/08—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents using activating agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE8686307356T 1985-09-26 1986-09-25 Sequenzierung von peptiden. Expired - Fee Related DE3685626T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US78026485A 1985-09-26 1985-09-26

Publications (2)

Publication Number Publication Date
DE3685626D1 true DE3685626D1 (de) 1992-07-16
DE3685626T2 DE3685626T2 (de) 1993-01-28

Family

ID=25119096

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8686307356T Expired - Fee Related DE3685626T2 (de) 1985-09-26 1986-09-25 Sequenzierung von peptiden.

Country Status (5)

Country Link
US (1) US4837165A (de)
EP (1) EP0217634B1 (de)
JP (1) JPH0718882B2 (de)
CA (1) CA1292840C (de)
DE (1) DE3685626T2 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4935494A (en) * 1988-11-15 1990-06-19 City Of Hope C-terminal peptide and protein sequencing
US5066785A (en) * 1988-11-15 1991-11-19 City Of Hope Carboxyl terminal peptide and protein sequencing
US5041388A (en) * 1989-12-21 1991-08-20 Applied Biosystems, Inc. C-terminal peptide sequencing, activated support and reagent system therefor, and method of producing the activated support
US5049507A (en) * 1989-12-21 1991-09-17 Applied Biosystems, Inc. Method of C-terminal peptide sequencing
DE69030316T2 (de) * 1990-05-18 1997-10-23 Hope City Schrittweiser c-terminaler abbau von peptiden und proteinen
US5059540A (en) * 1990-08-13 1991-10-22 City Of Hope Sequential C-terminal degradation of peptides and proteins using cleaving reagents such as sodium trimethylsilanolate or trimethylamine N-oxide
US5254475A (en) * 1990-08-13 1993-10-19 City Of Hope Sequential C-terminal degradation of peptides and proteins
US5051368A (en) * 1990-06-29 1991-09-24 Applied Biosystems, Inc. Method for forming an amino acid thiohydantoin using an N-substituted ketenimine activator
WO1992001938A1 (en) * 1990-07-20 1992-02-06 City Of Hope Derivatization of c-terminal proline
US5185266A (en) * 1991-10-15 1993-02-09 Applied Biosystems, Inc. Cleavage method for acyl thiohydantoins and use of the method in c-terminal peptide sequencing
US5304497A (en) * 1991-10-15 1994-04-19 Applied Biosystems, Inc. Method of forming N-protected amino acid thiohydantoins
US5180807A (en) * 1991-12-03 1993-01-19 City Of Hope C-terminal peptide or protein sequencing reagent and method
US5432092A (en) * 1991-12-03 1995-07-11 City Of Hope C-terminal peptide sequencing using diphenyl phosphoroisothiocyanatidate and pyridine
US5470703A (en) * 1992-10-21 1995-11-28 Shimadzu Corporation Method for peptide C-terminal fragment sequence analysis and apparatus for collecting peptide fragment
US5641685A (en) * 1995-04-24 1997-06-24 Smithkline Beecham Corporation Method carboxy terminal protein or peptide sequencing
AUPN896396A0 (en) * 1996-03-27 1996-04-26 Garvan Institute Of Medical Research Method for preparing amino acid thiohydantoins
JP3124507B2 (ja) * 1996-05-24 2001-01-15 セイコーインスツルメンツ株式会社 タンパク質あるいはペプチドのカルボキシ末端からのアミノ酸配列を決定する方法
US6756394B1 (en) * 1999-10-15 2004-06-29 President And Fellow Of Harvard College Small molecule inhibitors of necrosis
US7491743B2 (en) * 2003-08-29 2009-02-17 President And Fellows Of Harvard College Inhibitors of cellular necrosis
ES2524449T3 (es) * 2004-07-02 2014-12-09 Genentech, Inc. Inhibidores de IAP
CN101146803A (zh) 2004-12-20 2008-03-19 健泰科生物技术公司 Iap的吡咯烷抑制剂
EP1973899A4 (de) * 2005-12-19 2010-10-20 Genentech Inc Hemmer von iap
JP2010513561A (ja) * 2006-12-19 2010-04-30 ジェネンテック， インコーポレイテッド Ｉａｐのイミダゾピリジンインヒビター
TWI432212B (zh) * 2007-04-30 2014-04-01 Genentech Inc Ｉａｐ抑制劑
JP2011509938A (ja) * 2008-01-11 2011-03-31 ジェネンテック， インコーポレイテッド Ｉａｐのインヒビター
CA2730448A1 (en) 2008-08-02 2010-02-11 Genentech, Inc. Inhibitors of iap
CN102316735A (zh) 2008-12-23 2012-01-11 哈佛大学校长及研究员协会 坏死性凋亡的小分子抑制剂
JP2016514693A (ja) 2013-03-15 2016-05-23 プレジデント アンド フェローズ オブ ハーバード カレッジ ハイブリッド型ネクロトーシス阻害剤
JP2017538712A (ja) 2014-12-11 2017-12-28 プレジデント アンド フェローズ オブ ハーバード カレッジ 細胞壊死の抑制剤及びそれに関連する方法

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3725010A (en) 1971-08-23 1973-04-03 Beckman Instruments Inc Apparatus for automatically performing chemical processes
US4065412A (en) * 1976-05-07 1977-12-27 Durrum Instrument Corporation Peptide or protein sequencing method and apparatus

Also Published As

Publication number Publication date
EP0217634A2 (de) 1987-04-08
US4837165A (en) 1989-06-06
EP0217634B1 (de) 1992-06-10
JPS62156562A (ja) 1987-07-11
JPH0718882B2 (ja) 1995-03-06
EP0217634A3 (en) 1988-08-31
CA1292840C (en) 1991-12-03
DE3685626T2 (de) 1993-01-28

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee