DK224886A - Proteinbestemmelse - Google Patents

Proteinbestemmelse Download PDF

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Publication number
DK224886A
DK224886A DK224886A DK224886A DK224886A DK 224886 A DK224886 A DK 224886A DK 224886 A DK224886 A DK 224886A DK 224886 A DK224886 A DK 224886A DK 224886 A DK224886 A DK 224886A
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DK
Denmark
Prior art keywords
protein determination
protein
determination
Prior art date
Application number
DK224886A
Other languages
English (en)
Other versions
DK224886D0 (da
DK165199B (da
DK165199C (da
Inventor
Kurt F Stocker
G Svendsen Lars
Original Assignee
Pentapharm Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pentapharm Ag filed Critical Pentapharm Ag
Publication of DK224886D0 publication Critical patent/DK224886D0/da
Publication of DK224886A publication Critical patent/DK224886A/da
Publication of DK165199B publication Critical patent/DK165199B/da
Application granted granted Critical
Publication of DK165199C publication Critical patent/DK165199C/da

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/58Reptiles
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/34Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase
    • C12Q1/37Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving hydrolase involving peptidase or proteinase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/56Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving blood clotting factors, e.g. involving thrombin, thromboplastin, fibrinogen
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2337/00N-linked chromogens for determinations of peptidases and proteinases
    • C12Q2337/10Anilides
    • C12Q2337/12Para-Nitroanilides p-NA
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/46Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates
    • G01N2333/4609Assays involving biological materials from specific organisms or of a specific nature from animals; from humans from vertebrates from reptiles
    • G01N2333/4613Snake venom
    • G01N2333/462Snake venom from Agkistrodon sp., e.g. acutase, ACTE
    • G01N2333/4626Snake venom from Agkistrodon sp., e.g. acutase, ACTE from Agkistrodon contortrix contortrix (copperhead snake); Protac (R)
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/90Enzymes; Proenzymes
    • G01N2333/914Hydrolases (3)
    • G01N2333/948Hydrolases (3) acting on peptide bonds (3.4)
    • G01N2333/95Proteinases, i.e. endopeptidases (3.4.21-3.4.99)
    • G01N2333/964Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue
    • G01N2333/96425Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals
    • G01N2333/96427Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general
    • G01N2333/9643Proteinases, i.e. endopeptidases (3.4.21-3.4.99) derived from animal tissue from mammals in general with EC number
    • G01N2333/96433Serine endopeptidases (3.4.21)
    • G01N2333/96441Serine endopeptidases (3.4.21) with definite EC number
    • G01N2333/96461Protein C (3.4.21.69)
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02ATECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Analytical Chemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Neurosurgery (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DK224886A 1985-05-29 1986-05-14 Aktivatorpraeparat, fremgangsmaade til kvantitativ bestemmelse af protein c under anvendelse af praeparatet, antithrombotisk laegemiddel indeholdende praeparatet og fremgangsmaade til udvinding af aktiveret protein c under anvendelse af praeparatet DK165199C (da)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
CH226785 1985-05-29
CH226785 1985-05-29
CH413585 1985-09-25
CH413585 1985-09-25
CH508785 1985-11-28
CH508785 1985-11-28

Publications (4)

Publication Number Publication Date
DK224886D0 DK224886D0 (da) 1986-05-14
DK224886A true DK224886A (da) 1986-11-30
DK165199B DK165199B (da) 1992-10-19
DK165199C DK165199C (da) 1993-03-01

Family

ID=27173588

Family Applications (1)

Application Number Title Priority Date Filing Date
DK224886A DK165199C (da) 1985-05-29 1986-05-14 Aktivatorpraeparat, fremgangsmaade til kvantitativ bestemmelse af protein c under anvendelse af praeparatet, antithrombotisk laegemiddel indeholdende praeparatet og fremgangsmaade til udvinding af aktiveret protein c under anvendelse af praeparatet

Country Status (10)

Country Link
US (1) US4849403A (da)
EP (1) EP0203509B1 (da)
JP (1) JPH0736760B2 (da)
AU (1) AU605462B2 (da)
CA (1) CA1286223C (da)
DE (1) DE3678489D1 (da)
DK (1) DK165199C (da)
ES (2) ES8801037A1 (da)
IL (1) IL78829A (da)
NO (1) NO166303C (da)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3536903A1 (de) * 1985-10-16 1987-04-16 Boehringer Mannheim Gmbh Verfahren zur photometrischen bestimmung von protein c
DE3607559A1 (de) * 1986-03-07 1987-09-10 Boehringer Mannheim Gmbh Verfahren zur photometrischen bestimmung der protein c- und/oder protein s-aktivitaet
IT1197891B (it) * 1986-10-17 1988-12-21 Instrumentation Lab Spa Metodo per la determinazione dell'attivita' biologica della proteina c nel plasma umano, e relativi reagenti
JPH04505554A (ja) * 1989-02-17 1992-10-01 コドン 可溶性トロンボモジュリン類似体
FR2658517B2 (fr) * 1989-04-12 1992-06-19 Fondation Nale Transfusion San Preparation de la proteine c activee et solution de proteine c activee ainsi obtenue.
US5571786A (en) * 1990-08-16 1996-11-05 Immuno Aktiengesellschaft Use of protein C or the activation peptide of protein C for preparing a pharmaceutical preparation
AU2870992A (en) * 1991-10-04 1993-05-03 Board Of Regents Of The University Of Nebraska, The A soluble thrombomodulin-based one-stage assay for vitamin k-dependent coagulation-inhibiting proteins
US5716795A (en) * 1991-10-04 1998-02-10 Matschiner; John T. Thrombomodulin-based coagulometric assay of the protein C system
WO1993009807A1 (en) * 1991-11-18 1993-05-27 The Scripps Research Institute Methods of inhibiting thrombosis via elevation of circulating endogenous activated protein c levels
DE4203965A1 (de) * 1992-02-11 1993-08-12 Max Planck Gesellschaft Antidot fuer hirudin und synthetische thrombininhibitoren
US7169572B1 (en) 1993-01-29 2007-01-30 T.A.C. Thrombosis And Coagulation Ab Assays for determining anticoagulant cofactor activity
US5472852A (en) * 1993-09-15 1995-12-05 Oklahoma Medical Research Foundation Assay for detection of selective Protein C inhibition by patients
US7060484B1 (en) 1993-11-12 2006-06-13 Gilead Sciences, Inc. Polypeptides and coagulation therapy
CN1103815C (zh) * 1993-11-12 2003-03-26 吉里德科学公司 凝血酶突变体
WO1995030429A1 (en) * 1994-05-04 1995-11-16 Board Of Trustees Of The University Of Arkansas Novel ophthalmologic uses of protein c
AUPM731394A0 (en) * 1994-08-05 1994-09-01 Life Therapeutics Limited Improved activated protein c resistance test
DE4427785A1 (de) * 1994-08-08 1996-02-15 Behringwerke Ag Verfahren zum Nachweis von Störungen des Protein C/Protein S-Systems
US5780255A (en) * 1995-06-09 1998-07-14 Instrumentation Laboratory, S.P.A. Protein C pathway screening test
US6379975B1 (en) 1996-11-27 2002-04-30 T.A.C. Thrombosis And Coagulation Aktiebolag Methods and reagents for determining protein S
US6630137B1 (en) * 1997-04-28 2003-10-07 Eli Lilly And Company Activated protein C formulations
BR9809292A (pt) * 1997-04-28 2000-07-04 Lilly Co Eli Métodos aperfeiçoados para o processamento de proteìna c ativada
US7204981B2 (en) * 2000-03-28 2007-04-17 Eli Lilly And Company Methods of treating diseases with activated protein C
EP1289543A2 (en) 2000-05-24 2003-03-12 Eli Lilly And Company Formulations and methods for treating hypercoagulable states
US6855509B2 (en) 2000-12-19 2005-02-15 Instrumentation Laboratory Company Protein S functional assay and kit therefor
JP2005528351A (ja) * 2002-03-08 2005-09-22 イーライ・リリー・アンド・カンパニー 活性化プロテインc製剤
EP1367135A1 (en) * 2002-05-29 2003-12-03 Pentapharm AG Improved method for the assessment of thrombin formation in blood or plasma
CN102692511B (zh) * 2012-06-08 2015-04-15 上海太阳生物技术有限公司 蛋白c(pc)测定试剂盒(发色底物法)

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1293795A (en) * 1969-07-04 1972-10-25 Twyford Lab Ltd Improvements relating to anticoagulants
GB1472574A (en) * 1973-09-03 1977-05-04 Biochimici Fargal Pharmasint S Process for the extraction of components having anticoagulant activity -in vivo- from snake venoms and related products
CH626917A5 (da) * 1976-08-17 1981-12-15 Pentapharm Ag
US4341762A (en) * 1981-04-07 1982-07-27 Haast William E Use of snake venoms for treatment of neurological and related disorders
US4485176A (en) * 1982-06-28 1984-11-27 E. I. Du Pont De Nemours & Company Turbidimetric method for measuring protein in urine and cerebrospinal fluid
DE3330699A1 (de) * 1983-08-25 1985-03-07 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren zur gleichzeitigen bestimmung von fibrinogen und fibrinogen-spaltprodukten im plasma

Also Published As

Publication number Publication date
JPS61280298A (ja) 1986-12-10
EP0203509A2 (de) 1986-12-03
DK224886D0 (da) 1986-05-14
US4849403A (en) 1989-07-18
AU605462B2 (en) 1991-01-17
JPH0736760B2 (ja) 1995-04-26
NO166303B (no) 1991-03-18
DK165199B (da) 1992-10-19
NO862118L (no) 1986-12-01
ES8801037A1 (es) 1987-12-01
ES557670A0 (es) 1988-07-16
AU5736986A (en) 1986-12-04
EP0203509A3 (en) 1988-10-05
IL78829A (en) 1990-08-31
CA1286223C (en) 1991-07-16
IL78829A0 (en) 1986-09-30
EP0203509B1 (de) 1991-04-03
ES555428A0 (es) 1987-12-01
DK165199C (da) 1993-03-01
DE3678489D1 (de) 1991-05-08
ES8802471A1 (es) 1988-07-16
NO166303C (no) 1991-06-26

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Legal Events

Date Code Title Description
AHS Application shelved for other reasons than non-payment
AHB Application shelved due to non-payment
AHB Application shelved due to non-payment
PBP Patent lapsed

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