DE3650265D1 - Makrolide Antibiotika und Verfahren zu deren Herstellung. - Google Patents

Makrolide Antibiotika und Verfahren zu deren Herstellung.

Info

Publication number
DE3650265D1
DE3650265D1 DE3650265T DE3650265T DE3650265D1 DE 3650265 D1 DE3650265 D1 DE 3650265D1 DE 3650265 T DE3650265 T DE 3650265T DE 3650265 T DE3650265 T DE 3650265T DE 3650265 D1 DE3650265 D1 DE 3650265D1
Authority
DE
Germany
Prior art keywords
preparation
macrolide antibiotics
sup
compounds
hydroxyl group
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE3650265T
Other languages
English (en)
Other versions
DE3650265T2 (de
Inventor
John B Ward
Hazel M Noble
Neil Porter
Richard A Fletton
David Noble
Derek R Sutherland
Michael V J Ramsay
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Wyeth Holdings LLC
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB858522692A external-priority patent/GB8522692D0/en
Priority claimed from GB858522695A external-priority patent/GB8522695D0/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of DE3650265D1 publication Critical patent/DE3650265D1/de
Application granted granted Critical
Publication of DE3650265T2 publication Critical patent/DE3650265T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00—Antiparasitic agents
    • A61P33/10—Anthelmintics

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DE3650265T 1985-09-13 1986-09-12 Makrolide Antibiotika und Verfahren zu deren Herstellung. Expired - Fee Related DE3650265T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB858522692A GB8522692D0 (en) 1985-09-13 1985-09-13 Chemical compounds
GB858522695A GB8522695D0 (en) 1985-09-13 1985-09-13 Chemical compounds

Publications (2)

Publication Number Publication Date
DE3650265D1 true DE3650265D1 (de) 1995-04-20
DE3650265T2 DE3650265T2 (de) 1995-07-27

Family

ID=26289765

Family Applications (1)

Application Number Title Priority Date Filing Date
DE3650265T Expired - Fee Related DE3650265T2 (de) 1985-09-13 1986-09-12 Makrolide Antibiotika und Verfahren zu deren Herstellung.

Country Status (10)

Country Link
US (1) US4950683A (de)
EP (1) EP0215654B1 (de)
JP (1) JPH085893B2 (de)
AT (1) ATE119905T1 (de)
AU (1) AU598204B2 (de)
CA (1) CA1316915C (de)
DE (1) DE3650265T2 (de)
FI (1) FI100025B (de)
IE (1) IE67373B1 (de)
NZ (1) NZ217567A (de)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina
IE61058B1 (en) * 1986-01-23 1994-09-21 American Cyanamid Co Macrolide antibiotics and their preparation
GB8606116D0 (en) * 1986-03-12 1986-04-16 Glaxo Group Ltd Process
US5840704A (en) * 1986-07-16 1998-11-24 Pfizer Inc. Antiparasitic agents and process for their preparation
US5019589A (en) * 1986-09-12 1991-05-28 American Cyanamid Company Δ23 -LL-F28249 compounds
US5149832A (en) * 1986-09-12 1992-09-22 American Cyanamid Company Mono and diacyl derivatives of ll-f28249 compounds
EP0259779B1 (de) * 1986-09-12 1994-08-10 American Cyanamid Company 23-Oxo(keto) und 23-Imino-Derivate von LL-F28249-Verbindungen
EP0262384B1 (de) * 1986-09-12 1992-11-04 American Cyanamid Company 23-Deoxy-Derivate von LL-F28249-Verbindungen
US4886828A (en) * 1986-09-12 1989-12-12 American Cyanamid Company Δ22 -derivatives of LL-F28249 compounds
US5238848A (en) * 1987-01-23 1993-08-24 Pfizer Inc Cultures for production of avermectins
US5525506A (en) * 1987-01-23 1996-06-11 Pfizer Inc. Process for production of avermectins and cultures therefor
US5234831A (en) * 1987-01-23 1993-08-10 Pfizer Inc Cultures for production of B avermectins
US4886829A (en) * 1987-03-06 1989-12-12 American Cyanamid Company 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F28249 compounds
US4956479A (en) * 1987-03-06 1990-09-11 American Cyanamid Company 23-deoxy-27-chloro derivatives of LL-F28249 compounds
US4886830A (en) * 1987-03-06 1989-12-12 American Cyanamid Company Mono- and diepoxide derivatives of 23-deoxyl-LL-F28249 compounds
US4806527A (en) * 1987-03-16 1989-02-21 Merck & Co., Inc. Avermectin derivatives
JPS6431776A (en) * 1987-07-28 1989-02-02 Sankyo Co Novel macrolide compound and production thereof
US5240850A (en) * 1987-10-23 1993-08-31 Pfizer Inc. Cultures for production of avermectin aglycones
ATE87926T1 (de) * 1987-11-09 1993-04-15 Pfizer Ethylierte avermectine.
GB8726730D0 (en) * 1987-11-14 1987-12-16 Pfizer Ltd Antiparasitic agents
US4895837A (en) * 1988-01-29 1990-01-23 Merck & Co., Inc. Avermectin derivatives
US4918097A (en) * 1988-03-11 1990-04-17 Ciba-Geigy Corporation Insecticides and parasiticides
GB8813150D0 (en) * 1988-06-03 1988-07-06 American Cyanamid Co Chemical compounds
GB8813760D0 (en) * 1988-06-10 1988-07-13 American Cyanamid Co Chemical process
CA2052860A1 (en) * 1990-10-11 1992-04-12 Thomas L. Shih Avermectin degradation products and derivatives
US6103504A (en) * 1992-03-25 2000-08-15 Pfizer Inc. Process for production of avermectins and cultures therefor
KR100186946B1 (ko) * 1993-10-05 1999-04-01 알렌 제이.스피겔 도라멕틴의 구충활성 중간체 및 도라멕틴의 제조방법
US8080705B2 (en) 2004-07-28 2011-12-20 The Procter & Gamble Company Superabsorbent polymers comprising direct covalent bonds between polymer chain segments and method of making them
EP1669394A1 (de) * 2004-12-10 2006-06-14 The Procter & Gamble Company Superabsorbierende Polymerpartikel mit verbesserter Oberflächenvernetzung und hydrophiler Eigenschaft und Verfahren zur Herstellung
US20060128827A1 (en) * 2004-12-10 2006-06-15 The Procter & Gamble Company Absorbent members comprising modified water absorbent resin for use in diapers
JP2007077366A (ja) * 2005-09-16 2007-03-29 Procter & Gamble Co 吸水剤の製法
CA2649299A1 (en) * 2006-04-10 2007-10-25 The Procter & Gamble Company An absorbent member comprising a modified water absorbent resin
EP2121049B1 (de) 2007-02-22 2016-03-30 The Procter and Gamble Company Verfahren zur oberflächenbehandlung eines partikelförmigen materials mithilfe elektromagnetischer strahlung

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US32034A (en) * 1861-04-09 Langdon sawyer
US4201861A (en) * 1977-10-03 1980-05-06 Merck & Co., Inc. Acyl derivatives of C-076 compounds
USRE32034E (en) 1977-12-19 1985-11-19 Merck & Co., Inc. 13-Halo and 13-deoxy derivatives of C-076 compounds
PH16612A (en) * 1977-12-19 1983-11-28 Merck & Co Inc 13-halo and 13-deoxy derivatives of c-076 compounds
US4328335A (en) * 1979-08-13 1982-05-04 Merck & Co., Inc. Process for the interconversion of C-076 compounds
US4378353A (en) * 1981-02-17 1983-03-29 Merck & Co., Inc. Novel C-076 compounds
US4423209A (en) * 1982-02-26 1983-12-27 Merck & Co., Inc. Processes for the interconversion of avermectin compounds
JPS5916894A (ja) * 1982-07-21 1984-01-28 Sankyo Co Ltd ミルベマイシンｄの５−アシルオキシ誘導体
JPS5920284A (ja) * 1982-07-23 1984-02-01 Sankyo Co Ltd ミルベマイシンｄの５−エ−テル誘導体及びその塩
PT80577B (pt) * 1984-06-05 1987-09-18 American Cyanamid Co Processo para a producao de novos agentes macrolidos ll-f28249 uteis no tratamento de infeccoes helminticas por ectoparasitas artropodes e por acarideos
BE903232A (fr) * 1984-09-14 1986-03-13 Glaxo Group Ltd Composes antibiotiques et leur procede de preparation
US4587247A (en) * 1985-02-25 1986-05-06 Merck & Co., Inc. Substituted and unsubstituted 13-(alkoxy)methoxy derivatives of the avermectin aglycones, compositions and use
AU596586B2 (en) * 1985-04-30 1990-05-10 American Cyanamid Company Chemical derivatives of antibiotics S541
ES8800986A1 (es) * 1985-07-27 1987-12-01 Pfizer Un procedimiento para la produccion de un nuevo derivado de avermectina

Also Published As

Publication number Publication date
IE67373B1 (en) 1996-03-20
ATE119905T1 (de) 1995-04-15
JPS6267087A (ja) 1987-03-26
US4950683A (en) 1990-08-21
DE3650265T2 (de) 1995-07-27
FI100025B (fi) 1997-08-29
FI864150A (fi) 1988-04-15
NZ217567A (en) 1988-07-28
JPH085893B2 (ja) 1996-01-24
EP0215654A2 (de) 1987-03-25
AU6263486A (en) 1987-03-19
EP0215654A3 (en) 1987-07-22
AU598204B2 (en) 1990-06-21
IE862443L (en) 1987-03-13
FI864150A0 (fi) 1986-10-14
EP0215654B1 (de) 1995-03-15
CA1316915C (en) 1993-04-27

Similar Documents

Publication Publication Date Title
DE3650265D1 (de) Makrolide Antibiotika und Verfahren zu deren Herstellung.
ES9000023A1 (es) Un procedimiento para preparar nuevos antibioticos macrociclicos que contienen anillos de dihidrobenzofurano y de pirano
DK338187D0 (da) 13beta-milbemycinderivater samt deres fremstillingog anvendelse
MY102919A (en) Pleuromutilin derivatives process for their preparation and their use.
ES2038623T3 (es) Procedimiento para preparar soluciones de oxazafosforinas con estabilidad mejorada.
AU5034879A (en) Acid addition salt of 2beta,16beta diperidino 5 alpha androstane derivatives
MX9802655A (es) Nuevos derivados de la 5-0-desosaminil-6-metil-eritronolida a, su procedimiento de preparacion y su aplicacion para la preparacion de productos biologicamente activos.
DK288686A (da) Farmaceutiske praeparater
DE3787482D1 (de) Makrolid-Verbindungen.
FI890779A (fi) 14,17 -etano-14 -estratrieenejä, menetelmä niiden valmistamiseksi ja niitä sisältäviä, ehkäisyaineina käytettäviä valmisteita
IE890259L (en) Macrolide compounds
ES546995A0 (es) Procedimiento para la preparacion de derivados de pregnano
PT88462A (pt) Process for the preparation of macrolide compounds and of compositions containing them
FI875244A0 (fi) Foerfarande foer framstaellning av 6 ,9 -difluor-11 ,17 -dihydroxi-16--metyl-4-pregnen-3,20-dion och dess derivat.
EP0124252A3 (de) Doppel-Ester von 16-beta Ethyl 17-beta-Hydroxy-Estranderivaten
DK578083A (da) Antibiotika benaevnt a51568 faktor a og b og fremgangsmaade til fremstilling heraf
BG49444A1 (en) Acylureidoamynotiasolylni derivatives and method for their preparation
KR890001527A (ko) 에이즈 및 에이즈 관련 복합증상의 억제를 위한 아바콘, 아바롤 및 그 유도체의 용도
JPS54145638A (en) Novel derivative of xk-62-2
FI943596A (fi) Menetelmä terapeuttisesti käytt¦kelpoisten makrolidiyhdisteiden valmistamiseksi
KR880005080A (ko) 피리딘 유도체의 제조방법
GEP19970660B (en) Macrolide compounds
JPS5639081A (en) Benzthiazepine derivative
PT86422A (fr) Procede de preparation de derives d:acide dibenzo]be"-oxepine-acetique et de compositions pharmaceutiques les contenant

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee