BE903232A - Composes antibiotiques et leur procede de preparation - Google Patents
Composes antibiotiques et leur procede de preparationInfo
- Publication number
- BE903232A BE903232A BE0/215580A BE215580A BE903232A BE 903232 A BE903232 A BE 903232A BE 0/215580 A BE0/215580 A BE 0/215580A BE 215580 A BE215580 A BE 215580A BE 903232 A BE903232 A BE 903232A
- Authority
- BE
- Belgium
- Prior art keywords
- preparation
- antibiotic compounds
- compounds
- streptomyces
- agriculture
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/01—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing oxygen
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/10—Antimycotics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
- C12P17/18—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms containing at least two hetero rings condensed among themselves or condensed with a common carbocyclic ring system, e.g. rifamycin
- C12P17/181—Heterocyclic compounds containing oxygen atoms as the only ring heteroatoms in the condensed system, e.g. Salinomycin, Septamycin
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/465—Streptomyces
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biochemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- General Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Tropical Medicine & Parasitology (AREA)
- Pharmacology & Pharmacy (AREA)
- Virology (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
Les composés répondant à la formule (I) peuvent possèder un groupe 5-OH ou-OMe et, en position 25, un radical isopropylène à substitution méthylique, étylique ou isopropylique. Ces composés conviennent en agriculture ou en médecine comme substances antiparasitaires et se préparent par la culture de souches de Streptomyces, plus particulièrement de Streptomyces thermoarchaensis NCIB 12015.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB848423278A GB8423278D0 (en) | 1984-09-14 | 1984-09-14 | Antibiotic compounds |
GB848432519A GB8432519D0 (en) | 1984-12-21 | 1984-12-21 | Antibiotic compounds |
Publications (1)
Publication Number | Publication Date |
---|---|
BE903232A true BE903232A (fr) | 1986-03-13 |
Family
ID=26288220
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
BE0/215580A BE903232A (fr) | 1984-09-14 | 1985-09-13 | Composes antibiotiques et leur procede de preparation |
Country Status (33)
Country | Link |
---|---|
US (2) | US4898821A (fr) |
JP (2) | JPH07116199B2 (fr) |
KR (1) | KR940004098B1 (fr) |
AT (1) | AT396250B (fr) |
AU (1) | AU596565B2 (fr) |
BE (1) | BE903232A (fr) |
BG (1) | BG44205A3 (fr) |
BR (1) | BR8504457A (fr) |
CA (1) | CA1313155C (fr) |
CH (1) | CH666690A5 (fr) |
CS (1) | CS268803B2 (fr) |
DE (1) | DE3532794A1 (fr) |
DK (1) | DK162099C (fr) |
ES (2) | ES8704545A1 (fr) |
FI (1) | FI87366C (fr) |
FR (1) | FR2570390B1 (fr) |
GB (1) | GB2166436B (fr) |
GR (1) | GR852232B (fr) |
HU (1) | HU197046B (fr) |
IE (1) | IE59394B1 (fr) |
IL (1) | IL76385A (fr) |
IT (1) | IT1182857B (fr) |
LU (1) | LU86074A1 (fr) |
NL (1) | NL8502511A (fr) |
NZ (1) | NZ213463A (fr) |
PH (2) | PH21995A (fr) |
PL (1) | PL152148B1 (fr) |
PT (1) | PT81125B (fr) |
RO (1) | RO92478A (fr) |
SE (2) | SE502748C2 (fr) |
SU (1) | SU1738090A3 (fr) |
UA (1) | UA19162A (fr) |
ZW (1) | ZW15585A1 (fr) |
Families Citing this family (69)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
LV5536A3 (lv) * | 1984-09-14 | 1994-03-10 | American Cyanamid Co | Panemiens antibiotikas s-541 iegusanai streptomicetu celmi-antibiotikas s-541 producenti |
US4696922A (en) * | 1984-11-26 | 1987-09-29 | Ciba-Geigy Corporation | 5-azolylacetoxymilbemycins as ecto- and endoparasites |
AT399441B (de) * | 1985-04-30 | 1995-05-26 | American Cyanamid Co | Schädlingsbekämpfungsmittel und verfahren zur bekämpfung von schädlingen |
ES8802229A1 (es) * | 1985-04-30 | 1988-04-16 | Glaxo Group Ltd | Un procedimiento para preparar nuevos derivados lactonicos macrociclicos. |
ES8800986A1 (es) * | 1985-07-27 | 1987-12-01 | Pfizer | Un procedimiento para la produccion de un nuevo derivado de avermectina |
EP0215654B1 (fr) * | 1985-09-13 | 1995-03-15 | American Cyanamid Company | Antibiotiques du type macrolide et leur préparation |
AT398312B (de) * | 1986-03-12 | 1994-11-25 | American Cyanamid Co | Verfahren zur herstellung einer neuen makroliden verbindung |
NZ219575A (en) * | 1986-03-12 | 1990-04-26 | Glaxo Group Ltd | Phosphate, substituted alkoxy, or amino-carbonyloxy derivatives of milbemycin, and pesticidal compositions |
GB8606116D0 (en) * | 1986-03-12 | 1986-04-16 | Glaxo Group Ltd | Process |
GB8606120D0 (en) * | 1986-03-12 | 1986-04-16 | Glaxo Group Ltd | Process |
DE3707859A1 (de) * | 1986-03-12 | 1987-10-08 | Glaxo Group Ltd | Makrolidverbindung |
GB8606105D0 (en) * | 1986-03-12 | 1986-04-16 | Glaxo Group Ltd | Chemical compounds |
GB8613790D0 (en) * | 1986-06-06 | 1986-07-09 | Glaxo Group Ltd | Chemical compounds |
CA1296329C (fr) * | 1986-06-06 | 1992-02-25 | Derek R. Sutherland | Composes de type macrolide |
US5840704A (en) * | 1986-07-16 | 1998-11-24 | Pfizer Inc. | Antiparasitic agents and process for their preparation |
NZ221077A (en) * | 1986-07-18 | 1990-06-26 | Ciba Geigy Ag | 13b-alkyl milbemycins and use as parasiticides |
EP0254583B1 (fr) * | 1986-07-24 | 1994-09-07 | Beecham Group Plc | Dérivés de la milbémycine à activité parasiticide, un procédé pour leur préparation et les compositions les contenant |
US5149832A (en) * | 1986-09-12 | 1992-09-22 | American Cyanamid Company | Mono and diacyl derivatives of ll-f28249 compounds |
ATE109783T1 (de) * | 1986-09-12 | 1994-08-15 | American Cyanamid Co | 23-oxo(keto) und 23-imino-derivate von ll-f28249- verbindungen. |
EP0262384B1 (fr) * | 1986-09-12 | 1992-11-04 | American Cyanamid Company | Dérivés 23-déoxy des composés LL-F28249 |
US5019589A (en) * | 1986-09-12 | 1991-05-28 | American Cyanamid Company | Δ23 -LL-F28249 compounds |
US4886828A (en) * | 1986-09-12 | 1989-12-12 | American Cyanamid Company | Δ22 -derivatives of LL-F28249 compounds |
US4916154A (en) * | 1986-09-12 | 1990-04-10 | American Cyanamid Company | 23-Imino derivatives of LL-F28249 compounds |
US5525506A (en) * | 1987-01-23 | 1996-06-11 | Pfizer Inc. | Process for production of avermectins and cultures therefor |
US5238848A (en) * | 1987-01-23 | 1993-08-24 | Pfizer Inc | Cultures for production of avermectins |
US5234831A (en) * | 1987-01-23 | 1993-08-10 | Pfizer Inc | Cultures for production of B avermectins |
US5183749A (en) * | 1987-02-04 | 1993-02-02 | Sankyo Company, Ltd. | Microbial process for the preparation of milbemycin derivatives |
US4897416A (en) * | 1987-02-18 | 1990-01-30 | Ciba-Geigy Corporation | Insecticides and parasiticides |
US4876272A (en) * | 1987-03-06 | 1989-10-24 | American Cyanamid Company | Mono- and diepoxide derivatives of LL-F28249 compounds |
US4886830A (en) * | 1987-03-06 | 1989-12-12 | American Cyanamid Company | Mono- and diepoxide derivatives of 23-deoxyl-LL-F28249 compounds |
US4886829A (en) * | 1987-03-06 | 1989-12-12 | American Cyanamid Company | 23-Oxo (keto) and 23-imino derivatives of mono- and diepoxy LL-F28249 compounds |
US4851428A (en) * | 1987-03-06 | 1989-07-25 | American Cyanamid Company | Mono- and diepoxide derivatives of Δ22-LL-F28249 compounds |
US4956479A (en) * | 1987-03-06 | 1990-09-11 | American Cyanamid Company | 23-deoxy-27-chloro derivatives of LL-F28249 compounds |
US4855317A (en) * | 1987-03-06 | 1989-08-08 | Ciba-Geigy Corporation | Insecticides and parasiticides |
US4806527A (en) * | 1987-03-16 | 1989-02-21 | Merck & Co., Inc. | Avermectin derivatives |
US4871719A (en) * | 1987-03-24 | 1989-10-03 | Ciba-Geigy Corporation | Composition for controlling parasites in productive livestock |
EP0285561A3 (fr) * | 1987-03-27 | 1989-10-25 | Ciba-Geigy Ag | Dérivés de la milbémycine à activité antiparasitaire et insecticide |
GB8721377D0 (en) * | 1987-09-11 | 1987-10-21 | Glaxo Group Ltd | Chemical compounds |
GB8721378D0 (en) * | 1987-09-11 | 1987-10-21 | Glaxo Group Ltd | Chemical process |
GB8721375D0 (en) * | 1987-09-11 | 1987-10-21 | Glaxo Group Ltd | Chemical process |
GB8721647D0 (en) * | 1987-09-15 | 1987-10-21 | Pfizer Ltd | Antiparasitic agents |
US5240850A (en) * | 1987-10-23 | 1993-08-31 | Pfizer Inc. | Cultures for production of avermectin aglycones |
CA1340771C (fr) * | 1987-11-09 | 1999-09-28 | Shih-Jen Edward Lee | Avermectines ethylees |
GB8726730D0 (en) | 1987-11-14 | 1987-12-16 | Pfizer Ltd | Antiparasitic agents |
GB8803836D0 (en) * | 1988-02-18 | 1988-03-16 | Glaxo Group Ltd | Compositions |
GB8804440D0 (en) * | 1988-02-25 | 1988-03-23 | Pfizer Ltd | Antiparasitic agents |
GB8805978D0 (en) * | 1988-03-14 | 1988-04-13 | Glaxo Group Ltd | Process |
GB8813760D0 (en) * | 1988-06-10 | 1988-07-13 | American Cyanamid Co | Chemical process |
NZ232422A (en) * | 1989-02-16 | 1992-11-25 | Merck & Co Inc | 13-ketal milbemycin derivatives and parasiticides |
US5322692A (en) * | 1989-02-28 | 1994-06-21 | American Cyanamid Company | Sustained release bolus effective for the prolonged prevention, treatment or control of nematode, acarid and endo- and ectoparasitic infestations of ruminants |
US6001822A (en) * | 1989-04-11 | 1999-12-14 | Pfizer Inc. | Antiparasitic formulations |
ES2052173T3 (es) * | 1989-04-11 | 1994-07-01 | Pfizer | Composiciones inyectables que contienen 25-cyclohexil-avermectina b1. |
DK0426948T3 (da) | 1989-08-11 | 1996-05-28 | American Cyanamid Co | Arylpyrroler som insekticide, acaricide og nematodicide midler samt fremgangsmåder til deres fremstilling |
NZ234802A (en) * | 1989-08-14 | 1992-11-25 | Merck & Co Inc | Long acting injectable formulations comprising an avermectin compound and triacetin. treatment for internal and external parasites of animals |
US5830875A (en) * | 1989-10-30 | 1998-11-03 | Merck & Co., Inc. | 24-and 25-substituted avermectin and milbemycin derivatives |
US5055454A (en) * | 1989-10-30 | 1991-10-08 | Merck & Co., Inc. | 13-epi-avermectin derivatives useful as antiparasitic agents |
US5208222A (en) * | 1991-03-28 | 1993-05-04 | Merck & Co., Inc. | 4"-and 4'-alkylthio avermectin derivatives |
US5262400A (en) * | 1991-06-20 | 1993-11-16 | Merck & Co., Inc. | 4α-substituted avermectin derivatives |
MD24B1 (ro) * | 1991-07-09 | 1994-05-31 | Parfumerii Si Cosmetice Vioric | Compozitie de substante odorante |
GB9205007D0 (en) * | 1992-03-07 | 1992-04-22 | Pfizer Ltd | Antiparasitic agents |
US5229415A (en) * | 1992-03-24 | 1993-07-20 | Merck & Co., Inc. | Alkylthio alkyl avermectins are active antiparasitic agents |
US6103504A (en) * | 1992-03-25 | 2000-08-15 | Pfizer Inc. | Process for production of avermectins and cultures therefor |
US6486195B1 (en) * | 1993-08-19 | 2002-11-26 | Merck & Co., Inc. | Thermodynamically stable crystal form of 4″-deoxy-4″-epi-methylamino avermectin B1a/B1b benzoic acid salt and processes for its preparation |
JP2855181B2 (ja) | 1993-12-10 | 1999-02-10 | 敏雄 鈴木 | 松類の枯損防止用組成物及び防止方法 |
US6495591B1 (en) | 1997-10-02 | 2002-12-17 | Essential Therapeutics, Inc. | Fungal efflux pump inhibitors |
PT1197215E (pt) | 2000-10-10 | 2006-07-31 | Wyeth Corp | Composicoes antelminticas |
GB0205253D0 (en) * | 2002-03-06 | 2002-04-17 | Univ Gent | Immediate release pharmaceutical granule compositions and a continuous process for making them |
WO2006091038A1 (fr) * | 2005-02-25 | 2006-08-31 | Medigenes Co., Ltd. | Composition pharmaceutique pour le traitement de la dystrophie corneenne d'avellino comporte du plasma sanguin et ou du serum |
CN100394983C (zh) * | 2006-01-09 | 2008-06-18 | 浙江海正药业股份有限公司 | 含有大豆油的多拉菌素注射液 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4914624A (fr) * | 1972-06-08 | 1974-02-08 | ||
SE434277B (sv) * | 1976-04-19 | 1984-07-16 | Merck & Co Inc | Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis |
PH16612A (en) * | 1977-12-19 | 1983-11-28 | Merck & Co Inc | 13-halo and 13-deoxy derivatives of c-076 compounds |
US4173571A (en) * | 1977-12-19 | 1979-11-06 | Merck & Co., Inc. | 13-Halo and 13-deoxy derivatives of C-076 compounds |
US4171314A (en) * | 1977-12-19 | 1979-10-16 | Merck & Co., Inc. | 13-Halo and 13-deoxy C-076 compounds |
US4200581A (en) * | 1978-08-04 | 1980-04-29 | Merck & Co., Inc. | Alkyl derivatives of C-076 compounds |
NZ201681A (en) * | 1981-09-03 | 1985-11-08 | Merck & Co Inc | Avermectin derivatives and parasiticidal compositions |
PT80577B (pt) * | 1984-06-05 | 1987-09-18 | American Cyanamid Co | Processo para a producao de novos agentes macrolidos ll-f28249 uteis no tratamento de infeccoes helminticas por ectoparasitas artropodes e por acarideos |
ES8802229A1 (es) * | 1985-04-30 | 1988-04-16 | Glaxo Group Ltd | Un procedimiento para preparar nuevos derivados lactonicos macrociclicos. |
ES8800986A1 (es) * | 1985-07-27 | 1987-12-01 | Pfizer | Un procedimiento para la produccion de un nuevo derivado de avermectina |
-
1985
- 1985-09-13 ZW ZW155/85A patent/ZW15585A1/xx unknown
- 1985-09-13 HU HU853466A patent/HU197046B/hu not_active IP Right Cessation
- 1985-09-13 AT AT0268485A patent/AT396250B/de not_active IP Right Cessation
- 1985-09-13 CH CH3973/85A patent/CH666690A5/de not_active IP Right Cessation
- 1985-09-13 FR FR8513637A patent/FR2570390B1/fr not_active Expired
- 1985-09-13 IL IL76385A patent/IL76385A/xx not_active IP Right Cessation
- 1985-09-13 BR BR8504457A patent/BR8504457A/pt not_active IP Right Cessation
- 1985-09-13 PT PT81125A patent/PT81125B/pt not_active IP Right Cessation
- 1985-09-13 FI FI853520A patent/FI87366C/fi not_active IP Right Cessation
- 1985-09-13 IE IE226385A patent/IE59394B1/en not_active IP Right Cessation
- 1985-09-13 PH PH32776A patent/PH21995A/en unknown
- 1985-09-13 DE DE19853532794 patent/DE3532794A1/de not_active Ceased
- 1985-09-13 NZ NZ213463A patent/NZ213463A/xx unknown
- 1985-09-13 BE BE0/215580A patent/BE903232A/fr not_active IP Right Cessation
- 1985-09-13 AU AU47426/85A patent/AU596565B2/en not_active Ceased
- 1985-09-13 CS CS856546A patent/CS268803B2/cs unknown
- 1985-09-13 DK DK418085A patent/DK162099C/da not_active IP Right Cessation
- 1985-09-13 GB GB8522699A patent/GB2166436B/en not_active Expired
- 1985-09-13 PL PL1985255360A patent/PL152148B1/pl unknown
- 1985-09-13 SE SE8504254A patent/SE502748C2/sv not_active IP Right Cessation
- 1985-09-13 UA UA3957807A patent/UA19162A/uk unknown
- 1985-09-13 JP JP60201951A patent/JPH07116199B2/ja not_active Expired - Lifetime
- 1985-09-13 ES ES546962A patent/ES8704545A1/es not_active Expired
- 1985-09-13 LU LU86074A patent/LU86074A1/fr unknown
- 1985-09-13 SU SU853957807A patent/SU1738090A3/ru active
- 1985-09-13 KR KR1019850006691A patent/KR940004098B1/ko not_active IP Right Cessation
- 1985-09-13 BG BG8571701A patent/BG44205A3/xx unknown
- 1985-09-13 NL NL8502511A patent/NL8502511A/nl not_active Application Discontinuation
- 1985-09-13 RO RO85120100A patent/RO92478A/fr unknown
- 1985-09-13 CA CA000490631A patent/CA1313155C/fr not_active Expired - Fee Related
- 1985-09-13 IT IT48551/85A patent/IT1182857B/it active
- 1985-09-13 GR GR852232A patent/GR852232B/el unknown
- 1985-11-22 PH PH35113A patent/PH24247A/en unknown
-
1986
- 1986-12-01 ES ES557237A patent/ES8802555A1/es not_active Expired
-
1987
- 1987-03-25 US US07/029,885 patent/US4898821A/en not_active Expired - Lifetime
-
1988
- 1988-03-31 US US07/176,252 patent/US4935531A/en not_active Expired - Lifetime
- 1988-08-25 SE SE8802985A patent/SE469173B/sv not_active Application Discontinuation
-
1995
- 1995-01-05 JP JP7000317A patent/JP2566385B2/ja not_active Expired - Lifetime
Also Published As
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Date | Code | Title | Description |
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RE | Patent lapsed |
Owner name: AMERICAN CYANAMID CY Effective date: 19970930 |