DE3543982A1 - Indolderivate, verfahren zu ihrer herstellung und sie enthaltende, pharmazeutische zubereitungen - Google Patents

Indolderivate, verfahren zu ihrer herstellung und sie enthaltende, pharmazeutische zubereitungen

Info

Publication number
DE3543982A1
DE3543982A1 DE19853543982 DE3543982A DE3543982A1 DE 3543982 A1 DE3543982 A1 DE 3543982A1 DE 19853543982 DE19853543982 DE 19853543982 DE 3543982 A DE3543982 A DE 3543982A DE 3543982 A1 DE3543982 A1 DE 3543982A1
Authority
DE
Germany
Prior art keywords
group
indole
general formula
compound
hydrogen atom
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
DE19853543982
Other languages
German (de)
English (en)
Inventor
David Edmund Ware Hertfordshire Bays
Colin Frederick Royston Hertfordshire Webb
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of DE3543982A1 publication Critical patent/DE3543982A1/de
Withdrawn legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
    • C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
    • C07D209/16—Tryptamines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
DE19853543982 1984-12-13 1985-12-12 Indolderivate, verfahren zu ihrer herstellung und sie enthaltende, pharmazeutische zubereitungen Withdrawn DE3543982A1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB848431426A GB8431426D0 (en) 1984-12-13 1984-12-13 Chemical compounds

Publications (1)

Publication Number Publication Date
DE3543982A1 true DE3543982A1 (de) 1986-06-19

Family

ID=10571103

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19853543982 Withdrawn DE3543982A1 (de) 1984-12-13 1985-12-12 Indolderivate, verfahren zu ihrer herstellung und sie enthaltende, pharmazeutische zubereitungen

Country Status (11)

Country Link
JP (1) JPS61151172A (it)
AU (1) AU579687B2 (it)
BE (1) BE903846A (it)
CH (1) CH667454A5 (it)
DE (1) DE3543982A1 (it)
FR (1) FR2574793B1 (it)
GB (2) GB8431426D0 (it)
IT (1) IT1182089B (it)
NL (1) NL8503424A (it)
SE (1) SE8505887L (it)
ZA (1) ZA859520B (it)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8293781B2 (en) 2007-03-29 2012-10-23 Daiichi Sankyo Company, Limited Indole derivatives having cPLA2 inhibiting activity and applications and production methods of the same

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds
GB8607824D0 (en) * 1986-03-27 1986-04-30 Glaxo Group Ltd Chemical compounds
GB8614287D0 (en) * 1986-06-12 1986-07-16 Glaxo Group Ltd Chemical compounds
US4894386A (en) * 1987-04-15 1990-01-16 Ici Americas Inc. Aliphatic carboxamides
GB8719167D0 (en) * 1987-08-13 1987-09-23 Glaxo Group Ltd Chemical compounds
US5225431A (en) * 1987-10-23 1993-07-06 Burroughs Wellcome Co. Therapeutic substituted indole compounds and compositions thereof
SI21560B (sl) * 1990-06-07 2005-04-30 Astrazeneca Ab 3,5-disubstituirani indolni derivati kot "5-HT1-podobni" receptorski agonisti
GB9209882D0 (en) * 1992-05-07 1992-06-24 Glaxo Lab Sa Compositions
GB9211277D0 (en) 1992-05-28 1992-07-15 Glaxo Group Inc Pharmaceutical compositions
GB9216009D0 (en) * 1992-07-28 1992-09-09 Almirall Lab New indol derivatives
ES2056025B1 (es) * 1992-10-08 1995-05-01 Almirall Lab Nuevos derivados de indol.
FR2707639B1 (fr) * 1993-06-30 1995-10-13 Pf Medicament Nouveaux composés indoliques dérivés d'arylamines comme ligands sélectifs des récepteurs 5HT1D et 5HT1B.
EP2666772B1 (en) * 2002-12-20 2017-03-01 Basf Se Synthesis of amines and intermediates for the synthesis thereof
WO2005118551A2 (en) 2004-05-28 2005-12-15 Ligand Pharmaceuticals Inc. Thrombopoietin activity modulating compounds and methods
CA2583764C (en) 2004-10-25 2009-06-09 Ligand Pharmaceuticals, Inc. Thrombopoietin activity modulating compounds and methods

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA795239B (en) * 1978-10-12 1980-11-26 Glaxo Group Ltd Heterocyclic compounds
GB2082175B (en) * 1980-08-12 1984-05-02 Glaxo Group Ltd Heterocyclic compounds
FR2574077A1 (fr) * 1984-12-04 1986-06-06 Glaxo Group Ltd Derives d'indoles, leur preparation et les compositions pharmaceutiques les contenant
GB8530507D0 (en) * 1985-12-11 1986-01-22 Glaxo Group Plc Chemical compounds

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US8293781B2 (en) 2007-03-29 2012-10-23 Daiichi Sankyo Company, Limited Indole derivatives having cPLA2 inhibiting activity and applications and production methods of the same

Also Published As

Publication number Publication date
IT1182089B (it) 1987-09-30
IT8548921A0 (it) 1985-12-12
JPS61151172A (ja) 1986-07-09
FR2574793A1 (fr) 1986-06-20
GB8431426D0 (en) 1985-01-23
ZA859520B (en) 1986-08-27
NL8503424A (nl) 1986-07-01
GB8530591D0 (en) 1986-01-22
BE903846A (fr) 1986-06-12
AU5115185A (en) 1986-06-19
GB2168347B (en) 1988-02-03
SE8505887L (sv) 1986-06-14
SE8505887D0 (sv) 1985-12-12
GB2168347A (en) 1986-06-18
AU579687B2 (en) 1988-12-01
FR2574793B1 (fr) 1988-10-14
CH667454A5 (fr) 1988-10-14

Similar Documents

Publication Publication Date Title
DE3527648C2 (it)
DE3131748C2 (it)
US5340822A (en) Polycyclic amine compounds and their enantiomers, their method of preparation and pharmaceutical compositions in which they are present
DE3444572C2 (de) Indolderivate, Verfahren zu ihrer Herstellung, sie enthaltende pharmazeutische Zubereitungen und ihre Verwendung
DE3700408A1 (de) Indolderivate, sie enthaltende pharmazeutische zubereitungen und verfahren zu ihrer herstellung
DE60225162T2 (de) Phenylpiperazinderivate als serotonin wiederaufnahmehemmer
RU2120436C1 (ru) Четвертичные амиды основного характера, способ их получения и содержащая их фармацевтическая композиция
JP3560986B2 (ja) ５―ｈｔ２ｃ受容体作用薬及びアミノアルキルインダゾール誘導体
DE3543982A1 (de) Indolderivate, verfahren zu ihrer herstellung und sie enthaltende, pharmazeutische zubereitungen
JP2941309B2 (ja) 化合物
DE69922024T2 (de) Pyrrolochinoline zur Behandlung von Fettleibigkeit
JPH08333363A (ja) インドール誘導体
JPH07119213B2 (ja) ムスカリンリセプターアンタゴニスト
DE3131752C2 (it)
JPH07121943B2 (ja) ５−ｈｔ１アゴニストとしてのインドール誘導体
JP6498672B2 (ja) 疼痛に対して多重モードの活性を有するピペリジン化合物
US5670522A (en) Dopamine receptor subtype ligands
DE3542698A1 (de) Indolderivate, verfahren zu ihrer herstellung und sie enthaltende, pharmazeutische zubereitungen
PT94070A (pt) Processo para a preparacao de derivados de piperazina
JP4173912B2 (ja) ニューロキニンアンタゴニストとしてのピペラジノ誘導体
EP2280941B1 (de) (hetero-)aryl-cyclohexan-derivate
DE3700407A1 (de) Indolderivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zubereitungen
US5712288A (en) Quaternary basic amides, method of preparing them and pharmaceutical compositions in which they are present
WO2001070687A1 (de) Indole zur behandlung von krankheiten die mit schilddrüsenhormonen behandeln werden können
DD279674A5 (de) Verfahren zur herstellung von hydrierten 1-benzooxacycloalkyl-pyridincarbonsaeureverbindungen

Legal Events

Date Code Title Description
8141 Disposal/no request for examination