DE3538747A1 - Verfahren zur herstellung von pyrrolidin-derivaten - Google Patents
Verfahren zur herstellung von pyrrolidin-derivatenInfo
- Publication number
- DE3538747A1 DE3538747A1 DE19853538747 DE3538747A DE3538747A1 DE 3538747 A1 DE3538747 A1 DE 3538747A1 DE 19853538747 DE19853538747 DE 19853538747 DE 3538747 A DE3538747 A DE 3538747A DE 3538747 A1 DE3538747 A1 DE 3538747A1
- Authority
- DE
- Germany
- Prior art keywords
- formula
- compound
- reaction
- compounds
- sodium
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/04—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D207/10—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/16—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Pyrrole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
KR1019850000850A KR870001569B1 (ko) | 1985-02-11 | 1985-02-11 | 피롤리딘 유도체의 제조방법 |
Publications (2)
Publication Number | Publication Date |
---|---|
DE3538747A1 true DE3538747A1 (de) | 1986-08-14 |
DE3538747C2 DE3538747C2 (fr) | 1988-08-18 |
Family
ID=19239706
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE19853538747 Granted DE3538747A1 (de) | 1985-02-11 | 1985-10-31 | Verfahren zur herstellung von pyrrolidin-derivaten |
Country Status (6)
Country | Link |
---|---|
JP (1) | JPS61183263A (fr) |
KR (1) | KR870001569B1 (fr) |
DE (1) | DE3538747A1 (fr) |
ES (1) | ES8606269A1 (fr) |
FR (1) | FR2577222B1 (fr) |
GB (1) | GB2170806B (fr) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT395148B (de) * | 1990-09-21 | 1992-09-25 | Egyt Gyogyszervegyeszeti Gyar | Verfahren zur herstellung von 1-(3-mercapto-(2s)methyl-1-oxo-propyl)-l-prolin |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5237073A (en) * | 1988-08-26 | 1993-08-17 | Sepracor, Inc. | Derivatives and precursors of captopril and its analogues |
WO1990002118A1 (fr) * | 1988-08-26 | 1990-03-08 | Sepracor, Inc. | Derives et precurseurs de captopril et ses analogues |
KR940005014B1 (ko) * | 1991-11-07 | 1994-06-09 | 보령제약 주식회사 | 피롤리딘카르복실산 유도체의 제조방법 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
GB2066252A (en) * | 1979-12-29 | 1981-07-08 | Egyt Gyogyszervegyeszeti Gyar | Process for the preparation of 1-(3-mercapto-/2s/-methylpropionyl)-pyrrolidine-/2s/-carboxylic acid |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU509899B2 (en) * | 1976-02-13 | 1980-05-29 | E.R. Squibb & Sons, Inc. | Proline derivatives and related compounds |
US4192945A (en) * | 1978-12-07 | 1980-03-11 | E. R. Squibb & Sons, Inc. | Process for preparing proline and homoproline derivatives |
GB2065643B (en) * | 1979-12-13 | 1983-08-24 | Kanegafuchi Chemical Ind | Optically active n-mercaptoalkanoylamino acids |
JPS58124764A (ja) * | 1982-01-20 | 1983-07-25 | Kanegafuchi Chem Ind Co Ltd | 光学活性チオ−ル化合物の製造法 |
-
1985
- 1985-02-11 KR KR1019850000850A patent/KR870001569B1/ko not_active IP Right Cessation
- 1985-10-31 DE DE19853538747 patent/DE3538747A1/de active Granted
- 1985-11-11 ES ES548744A patent/ES8606269A1/es not_active Expired
- 1985-12-16 JP JP60282703A patent/JPS61183263A/ja active Pending
-
1986
- 1986-02-05 GB GB08602782A patent/GB2170806B/en not_active Expired
- 1986-02-11 FR FR8601839A patent/FR2577222B1/fr not_active Expired
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4046889A (en) * | 1976-02-13 | 1977-09-06 | E. R. Squibb & Sons, Inc. | Azetidine-2-carboxylic acid derivatives |
GB2066252A (en) * | 1979-12-29 | 1981-07-08 | Egyt Gyogyszervegyeszeti Gyar | Process for the preparation of 1-(3-mercapto-/2s/-methylpropionyl)-pyrrolidine-/2s/-carboxylic acid |
JPS56100760A (en) * | 1979-12-29 | 1981-08-12 | Egyt Gyogyszervegyeszeti Gyar | Manufacture of 11*33mercaptoo*2s** methylpropionyl**pyrrolidinee*2s**carboxylic acid |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT395148B (de) * | 1990-09-21 | 1992-09-25 | Egyt Gyogyszervegyeszeti Gyar | Verfahren zur herstellung von 1-(3-mercapto-(2s)methyl-1-oxo-propyl)-l-prolin |
Also Published As
Publication number | Publication date |
---|---|
FR2577222A1 (fr) | 1986-08-14 |
GB2170806A (en) | 1986-08-13 |
JPS61183263A (ja) | 1986-08-15 |
KR860006441A (ko) | 1986-09-11 |
GB2170806B (en) | 1988-08-03 |
FR2577222B1 (fr) | 1987-12-24 |
DE3538747C2 (fr) | 1988-08-18 |
GB8602782D0 (en) | 1986-03-12 |
ES548744A0 (es) | 1986-04-01 |
KR870001569B1 (ko) | 1987-09-04 |
ES8606269A1 (es) | 1986-04-01 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8110 | Request for examination paragraph 44 | ||
D2 | Grant after examination | ||
8363 | Opposition against the patent | ||
8328 | Change in the person/name/address of the agent |
Free format text: ZELLENTIN, R., DIPL.-GEOLOGE DR.RER.NAT., 8000 MUENCHEN ZELLENTIN, W., DIPL.-ING. GRUSSDORF, J., DIPL.-CHEM. DR.RER.NAT., PAT.-ANWAELTE, 6700 LUDWIGSHAFEN |
|
8331 | Complete revocation |