DE2962235D1 - 2'-deoxy-5-fluorouridine derivatives, a process for producing the same and antitumor agents comprising the same - Google Patents

2'-deoxy-5-fluorouridine derivatives, a process for producing the same and antitumor agents comprising the same

Info

Publication number
DE2962235D1
DE2962235D1 DE7979301782T DE2962235T DE2962235D1 DE 2962235 D1 DE2962235 D1 DE 2962235D1 DE 7979301782 T DE7979301782 T DE 7979301782T DE 2962235 T DE2962235 T DE 2962235T DE 2962235 D1 DE2962235 D1 DE 2962235D1
Authority
DE
Germany
Prior art keywords
same
deoxy
antitumor agents
fluorouridine
producing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979301782T
Other languages
English (en)
Inventor
Setsuro Fujii
Euchi Sakakibara
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Funai Pharmaceutical Industries Ltd
Original Assignee
Funai Pharmaceutical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Funai Pharmaceutical Industries Ltd filed Critical Funai Pharmaceutical Industries Ltd
Application granted granted Critical
Publication of DE2962235D1 publication Critical patent/DE2962235D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE7979301782T 1978-09-05 1979-08-31 2'-deoxy-5-fluorouridine derivatives, a process for producing the same and antitumor agents comprising the same Expired DE2962235D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP10895578A JPS5535057A (en) 1978-09-05 1978-09-05 2'-deoxy-5-fluorouridine derivative, its preparation, and antitumor agent comprising it

Publications (1)

Publication Number Publication Date
DE2962235D1 true DE2962235D1 (en) 1982-04-01

Family

ID=14497883

Family Applications (1)

Application Number Title Priority Date Filing Date
DE7979301782T Expired DE2962235D1 (en) 1978-09-05 1979-08-31 2'-deoxy-5-fluorouridine derivatives, a process for producing the same and antitumor agents comprising the same

Country Status (7)

Country Link
US (2) US4599404A (de)
EP (1) EP0009882B1 (de)
JP (1) JPS5535057A (de)
AT (1) ATE733T1 (de)
CA (1) CA1121811A (de)
DE (1) DE2962235D1 (de)
ES (1) ES483854A1 (de)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5924999B2 (ja) * 1978-06-10 1984-06-13 富山化学工業株式会社 新規な５−フルオロ−２′−デオキシ−β−ウリジン誘導体の製造法
GB2072164B (en) * 1980-02-15 1983-12-21 Funai Pharmaceutical Ind Ltd 2'-deoxy-3',5'-di-o-alkylcarbonyl-5-fluorouridine derivatives a process for the preparation of the derivatives and antitumor agents containing the derivatives
EP0082668A1 (de) * 1981-12-18 1983-06-29 Beecham Group Plc 5-(2-Halogenvinyl)-2'-Deoxyuridinderivate, Verfahren zu ihrer Herstellung, die sie enthaltende pharmazeutische Präparate und ihre Verwendung bei der Bekämpfung von viralen Infektionen
JPS6041924A (ja) * 1984-07-17 1985-03-05 松下電器産業株式会社 飲料製造機
JPS6041922A (ja) * 1984-07-17 1985-03-05 松下電器産業株式会社 飲料製造機
US4864021A (en) * 1984-10-30 1989-09-05 Otsuka Pharmaceutical Co., Ltd. 5-fluorouracil derivatives
DE3583726D1 (de) * 1984-10-30 1991-09-12 Otsuka Pharma Co Ltd 5-fluoruracilderivate.
JPH0678478B2 (ja) * 1986-03-19 1994-10-05 ユニチカ株式会社 熱可塑性樹脂組成物
DE3786834T2 (de) * 1986-04-30 1994-03-03 Otsuka Pharma Co Ltd 5-Fluoro-Uracil-Derivate.
AU610913B2 (en) * 1987-07-31 1991-05-30 Taiho Pharmaceutical Co., Ltd. 2'-deoxy-5-fluorouridine derivatives
US4992534A (en) * 1987-08-12 1991-02-12 Otsuka Pharmaceutical Co., Ltd. 3'-O-,5'-O-derivatives of 2'-deoxy-5-fluorouridine
US4981908A (en) * 1988-02-02 1991-01-01 E. I. Du Pont De Nemours And Company Thermoplastic elastomer blends
AU610344B2 (en) * 1988-02-29 1991-05-16 Taiho Pharmaceutical Co., Ltd. 2'-deoxy-5-fluorouridine derivatives
US7160537B2 (en) * 2003-12-15 2007-01-09 Siemens Medical Solutions Usa, Inc. Method for preparing radiolabeled thymidine having low chromophoric byproducts
US20050131224A1 (en) * 2003-12-15 2005-06-16 Cti Pet Systems, Inc. Method for preparing radiolabeled thymidine
CN113234064B (zh) * 2021-05-27 2022-03-29 西南医科大学附属中医医院 一种替加氟衍生物及其制备方法与应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3168513A (en) * 1962-03-02 1965-02-02 Hoffmann La Roche Derivative of 2'-deoxy-5-fluorouridine
US3309359A (en) * 1965-10-22 1967-03-14 Hoffmann La Roche N-mono-acyl-5-fluorocytosine derivatives and process
US3975367A (en) * 1971-06-08 1976-08-17 The Upjohn Company Arabinofuranosyl N4 -aminoacyl cytosine containing compounds
DE2614946A1 (de) * 1975-04-08 1976-10-14 Asahi Chemical Ind Neue nucleotidderivate
DE2658672A1 (de) * 1976-12-23 1978-06-29 Robugen Gmbh Neue nucleosid-verbindungen und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
CA1121811A (en) 1982-04-13
ATE733T1 (de) 1982-03-15
JPS5535057A (en) 1980-03-11
JPS5611718B2 (de) 1981-03-16
ES483854A1 (es) 1980-09-01
US4599404A (en) 1986-07-08
EP0009882A1 (de) 1980-04-16
EP0009882B1 (de) 1982-03-03
US4490366A (en) 1984-12-25

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee