DE2514084A1 - Neue indolverbindungen - Google Patents

Neue indolverbindungen

Info

Publication number
DE2514084A1
DE2514084A1 DE19752514084 DE2514084A DE2514084A1 DE 2514084 A1 DE2514084 A1 DE 2514084A1 DE 19752514084 DE19752514084 DE 19752514084 DE 2514084 A DE2514084 A DE 2514084A DE 2514084 A1 DE2514084 A1 DE 2514084A1
Authority
DE
Germany
Prior art keywords
fluorine
hydrogen
compound according
chlorine
tetrahydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Ceased
Application number
DE19752514084
Other languages
German (de)
English (en)
Inventor
Charles Armon Harbert
Jacob John Plattner
James Ray Tretter
Jun Willard Mckowan Welch
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US456641A external-priority patent/US3925409A/en
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of DE2514084A1 publication Critical patent/DE2514084A1/de
Ceased legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biomedical Technology (AREA)
  • Anesthesiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Epidemiology (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
DE19752514084 1974-04-01 1975-03-29 Neue indolverbindungen Ceased DE2514084A1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US45664074A 1974-04-01 1974-04-01
US456641A US3925409A (en) 1974-04-01 1974-04-01 4-Aryl-1,2,3,4-tetrahydropyrrolo{8 3,4-b{9 indoles

Publications (1)

Publication Number Publication Date
DE2514084A1 true DE2514084A1 (de) 1975-11-20

Family

ID=27038317

Family Applications (1)

Application Number Title Priority Date Filing Date
DE19752514084 Ceased DE2514084A1 (de) 1974-04-01 1975-03-29 Neue indolverbindungen

Country Status (15)

Country Link
JP (1) JPS587635B2 (fi)
AR (2) AR206812A1 (fi)
AU (1) AU7955975A (fi)
DD (1) DD118879A5 (fi)
DE (1) DE2514084A1 (fi)
DK (2) DK130575A (fi)
ES (3) ES436157A1 (fi)
FI (1) FI750940A (fi)
FR (1) FR2265368A1 (fi)
IL (1) IL46925A0 (fi)
LU (1) LU72182A1 (fi)
NL (1) NL7503700A (fi)
NO (1) NO751055L (fi)
RO (1) RO72884A (fi)
SE (2) SE423630B (fi)

Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0094774A2 (en) * 1982-05-17 1983-11-23 Pfizer Inc. Carboline derivatives
BG65162B1 (bg) * 1998-12-21 2007-04-30 Janssen Pharmaceutica N.V. Бензизоксазоли и фенони като алфа 2-антагонисти
WO2008026965A1 (fr) * 2006-08-24 2008-03-06 Alla Chem, Llc Pyrrolo[4,3-b]indoles substitués, bibliothèques focalisées ou combinatoires, composition pharmaceutique, procédé de fabrication et d'utilisation

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4224329A (en) * 1979-01-23 1980-09-23 Pfizer Inc. 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles
RU2591194C2 (ru) * 2010-04-22 2016-07-10 Интра-Селлулар Терапиз, Инк. Органические соединения

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0094774A2 (en) * 1982-05-17 1983-11-23 Pfizer Inc. Carboline derivatives
EP0094774A3 (en) * 1982-05-17 1984-12-19 Pfizer Inc. Carboline derivatives
BG65162B1 (bg) * 1998-12-21 2007-04-30 Janssen Pharmaceutica N.V. Бензизоксазоли и фенони като алфа 2-антагонисти
WO2008026965A1 (fr) * 2006-08-24 2008-03-06 Alla Chem, Llc Pyrrolo[4,3-b]indoles substitués, bibliothèques focalisées ou combinatoires, composition pharmaceutique, procédé de fabrication et d'utilisation

Also Published As

Publication number Publication date
RO72884B (ro) 1983-07-30
DK130575A (fi) 1975-10-02
NO751055L (fi) 1975-10-02
JPS50140494A (fi) 1975-11-11
ES453788A1 (es) 1978-01-01
NL7503700A (nl) 1975-10-03
DK187878A (da) 1978-05-01
LU72182A1 (fi) 1976-03-02
AR207799A1 (es) 1976-10-29
FR2265368A1 (en) 1975-10-24
DD118879A5 (fi) 1976-03-20
ES436157A1 (es) 1977-04-16
RO72884A (ro) 1983-08-03
SE7502927L (fi) 1975-10-02
SE423630B (sv) 1982-05-17
AU7955975A (en) 1976-09-30
SE8200047L (sv) 1982-01-07
ES453787A1 (es) 1978-01-01
JPS587635B2 (ja) 1983-02-10
FI750940A (fi) 1975-10-02
FR2265368B1 (fi) 1978-07-28
IL46925A0 (en) 1975-05-22
AR206812A1 (es) 1976-08-23

Similar Documents

Publication Publication Date Title
EP0005205B1 (de) Substituierte 5,6-Dimethylpyrrolo(2,3-d)pyrimidine, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE69716062T2 (de) Benzofuran-derivate und deren verwendung
DE3432983A1 (de) 1,5-disubstituierte 1h-pyrazolo(3,4-b)-pyrazin-derivate und antitumormittel, die diese enthalten
DE1795769B2 (de) 6,7A9-Tetrahydro-2H-pyrido [1,2-a] pyrimidinderivate, deren Salze mit Säuren und quaternär? Methosalze, Verfahren zu deren Herstellung sowie diese Verbindungen enthaltende Arzneimittel
EP0314154A2 (de) Tetrahydro-furo- und -thieno[2,3-c]pyridine, ihre Verwendung als Arzneimittel und Verfahren zu ihrer Herstellung
CH648553A5 (de) Neue 3,4-dihydro-5h-2,3-benzodiazepin-derivate und verfahren zur herstellung derselben.
DE2506770A1 (de) Piperidinderivate
DE3430284A1 (de) Neue tryptamin-derivate, ein verfahren zu ihrer herstellung und ihre verwendung
DE2149249B2 (de) 4-Amino-6-arylpyrimidine
DE2815724A1 (de) Indolderivate, verfahren zu ihrer herstellung und sie enthaltende arzneimittel
DE2720085C2 (fi)
DE2822465C2 (de) 2-substituierte trans-5-Phenyl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indolderivate und diese enthaltende Arzneimittel
DE2523103A1 (de) Neue propargyl-2-phenylamino-imidazoline-(2), deren saeureadditionssalze, diese enthaltende arzneimittel und verfahren zur herstellung derselben
DE2726389A1 (de) Pyrazolo eckige klammer auf 1,5-c eckige klammer zu chinazoline, verfahren zu deren herstellung und diese verbindungen enthaltende arzneimittel
DE2514084A1 (de) Neue indolverbindungen
DE3854991T2 (de) Cyclische Amine und pharmakologische Verbindungen
EP0331093A1 (de) Neue Benzimidazo[1,2-c] chinazoline, ihre Herstellung und Verwendung
DE2836449A1 (de) 2,3-polymethylen-4-oxo-4h-pyrido (1,2-a) pyrimidine und ein verfahren zur herstellung derselben
DE2521920A1 (de) Neue derivate von 1h-triazolo(4,5-c) pyridin-7-carbonsaeuren und -saeureestern
DE2051961A1 (de) 6 substituierte Indol eckige Klammer auf 1,2 c eckige Klammer zu chinazoline und Verfahren zu deren Herstellung
AT390791B (de) Verfahren zur herstellung neuer kondensierter as-triazinium-derivate sowie von deren isomeren
EP0120439B1 (de) 7,8,9,10-Tetrahydrothieno-(3,2-e)-pyrido-(4,3-b)-indole, Verfahren zu ihrer Herstellung und diese enthaltende Arzneimittel
DE3245950A1 (de) Verfahren zur herstellung substituierter pyridine
DE69431441T2 (de) Trizyklische verbindungen mit affinität für den 5-ht1a rezeptor
AT375079B (de) Verfahren zur herstellung von neuen trans-2,3,4,4a ,5,9b-hexahydro-1h-pyrido(4,3-b)indolen und ihren pharmazeutisch annehmbaren salzen

Legal Events

Date Code Title Description
8110 Request for examination paragraph 44
8131 Rejection