DE122005000030I2 - Pregna-1,4-dien-3,20-dion-16-17-acetal-21-ester, Verfahren zur Herstellung, sowie diese enthaltende pharmazeutische Präparate - Google Patents

Pregna-1,4-dien-3,20-dion-16-17-acetal-21-ester, Verfahren zur Herstellung, sowie diese enthaltende pharmazeutische Präparate

Info

Publication number
DE122005000030I2
DE122005000030I2 DE200512000030 DE122005000030C DE122005000030I2 DE 122005000030 I2 DE122005000030 I2 DE 122005000030I2 DE 200512000030 DE200512000030 DE 200512000030 DE 122005000030 C DE122005000030 C DE 122005000030C DE 122005000030 I2 DE122005000030 I2 DE 122005000030I2
Authority
DE
Germany
Prior art keywords
pregna
dione
acetal
diene
esters
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Active
Application number
DE200512000030
Other languages
English (en)
Other versions
DE122005000030I1 (de
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda GmbH
Original Assignee
Altana Pharma AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Altana Pharma AG filed Critical Altana Pharma AG
Publication of DE122005000030I1 publication Critical patent/DE122005000030I1/de
Publication of DE122005000030I2 publication Critical patent/DE122005000030I2/de
Active legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0092—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by an OH group free esterified or etherified
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/58—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids containing heterocyclic rings, e.g. danazol, stanozolol, pancuronium or digitogenin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A61P5/38—Drugs for disorders of the endocrine system of the suprarenal hormones
    • A61P5/44—Glucocorticosteroids; Drugs increasing or potentiating the activity of glucocorticosteroids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
    • C07J71/0005—Oxygen-containing hetero ring
    • C07J71/0026—Oxygen-containing hetero ring cyclic ketals
    • C07J71/0031—Oxygen-containing hetero ring cyclic ketals at positions 16, 17

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Diabetes (AREA)
  • Endocrinology (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE200512000030 1990-09-07 1991-09-05 Pregna-1,4-dien-3,20-dion-16-17-acetal-21-ester, Verfahren zur Herstellung, sowie diese enthaltende pharmazeutische Präparate Active DE122005000030I2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US57894290A 1990-09-07 1990-09-07

Publications (2)

Publication Number Publication Date
DE122005000030I1 DE122005000030I1 (de) 2005-10-06
DE122005000030I2 true DE122005000030I2 (de) 2007-12-06

Family

ID=24314964

Family Applications (2)

Application Number Title Priority Date Filing Date
DE4129535A Expired - Lifetime DE4129535C2 (de) 1990-09-07 1991-09-05 Pregna-1,4-dien-3,20-dion-16-17-acetal-21-ester, Verfahren zur Herstellung, sowie diese enthaltende pharmazeutische Präparate
DE200512000030 Active DE122005000030I2 (de) 1990-09-07 1991-09-05 Pregna-1,4-dien-3,20-dion-16-17-acetal-21-ester, Verfahren zur Herstellung, sowie diese enthaltende pharmazeutische Präparate

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE4129535A Expired - Lifetime DE4129535C2 (de) 1990-09-07 1991-09-05 Pregna-1,4-dien-3,20-dion-16-17-acetal-21-ester, Verfahren zur Herstellung, sowie diese enthaltende pharmazeutische Präparate

Country Status (19)

Country Link
US (1) US5482934A (de)
JP (1) JP3292928B2 (de)
KR (1) KR100193085B1 (de)
AT (1) AT402930B (de)
AU (1) AU649472B2 (de)
BE (1) BE1005876A5 (de)
BR (1) BR1100860A (de)
CA (1) CA2050812C (de)
CH (1) CH683343A5 (de)
DE (2) DE4129535C2 (de)
ES (1) ES2034893B1 (de)
FR (1) FR2666585B1 (de)
GB (1) GB2247680B (de)
GR (1) GR1001529B (de)
HK (1) HK1005881A1 (de)
IT (1) IT1251376B (de)
LU (2) LU88001A1 (de)
NL (2) NL194917C (de)
PT (1) PT98897B (de)

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SE8008524L (sv) * 1980-12-04 1982-06-05 Draco Ab 4-pregnen-derivat, ett forfarande for deras framstellning, beredning och metod for behandling av inflammatoriska tillstand
IT1196142B (it) * 1984-06-11 1988-11-10 Sicor Spa Procedimento per la preparazione di 16,17-acetali di derivati pregnanici e nuovi composti ottenuti
SE8604059D0 (sv) * 1986-09-25 1986-09-25 Astra Pharma Prod A method of controlling the epimeric distribution in the preparation of 16,17-acetals of pregnane derivatives
DE3640709A1 (de) * 1986-11-28 1988-06-09 Schering Ag Verfahren zur herstellung von 6(alpha),9(alpha)-difluor-11ss,17(alpha)-dihydroxy-16(alpha)-methyl-4-pregnen-3,20-dion und dessen derivate

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FR2666585A1 (fr) 1992-03-13
CA2050812A1 (en) 1992-03-08
FR2666585B1 (fr) 1994-09-09
AU649472B2 (en) 1994-05-26
GR1001529B (el) 1994-03-31
JPH04257599A (ja) 1992-09-11
NL194917C (nl) 2003-09-01
NL9101472A (nl) 1992-04-01
AU8368691A (en) 1992-03-12
CH683343A5 (de) 1994-02-28
GB2247680A (en) 1992-03-11
CA2050812C (en) 2003-07-29
US5482934A (en) 1996-01-09
ATA176991A (de) 1997-02-15
KR100193085B1 (ko) 1999-06-15
ES2034893A1 (es) 1993-04-01
ITMI912296A0 (it) 1991-08-28
LU88001A1 (fr) 1992-06-01
DE4129535C2 (de) 2001-03-15
NL300196I2 (nl) 2005-10-03
ITMI912296A1 (it) 1993-02-28
DE122005000030I1 (de) 2005-10-06
LU91205I2 (fr) 2006-05-30
GB2247680B (en) 1994-06-01
HK1005881A1 (en) 1999-01-29
GB9118967D0 (en) 1991-10-23
DE4129535A1 (de) 1992-03-12
AT402930B (de) 1997-09-25
JP3292928B2 (ja) 2002-06-17
PT98897B (pt) 2000-10-31
BR1100860A (pt) 1999-08-31
PT98897A (pt) 1992-07-31
ES2034893B1 (es) 1994-01-01
NL300196I1 (nl) 2005-08-01
BE1005876A5 (nl) 1994-02-22
IT1251376B (it) 1995-05-09
GR910100353A (en) 1992-09-11
KR920006365A (ko) 1992-04-27

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