DE10347311A1 - Verfahren und Vorrichtung zur Durchführung von Reaktionen - Google Patents

Verfahren und Vorrichtung zur Durchführung von Reaktionen Download PDF

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Publication number
DE10347311A1
DE10347311A1 DE2003147311 DE10347311A DE10347311A1 DE 10347311 A1 DE10347311 A1 DE 10347311A1 DE 2003147311 DE2003147311 DE 2003147311 DE 10347311 A DE10347311 A DE 10347311A DE 10347311 A1 DE10347311 A1 DE 10347311A1
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Germany
Prior art keywords
reaction
carrying
out reactions
time
path
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DE2003147311
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Inventor
Wolfgang Ehrfeld
Karoly Nagy
Alexander Azzawi
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Ehrfeld Mikrotechnik BTS GmbH
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EHRFELD MIKROTECHNIK AG
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Priority to DE2003147311 priority Critical patent/DE10347311A1/de
Priority to PCT/EP2004/011291 priority patent/WO2005035110A1/de
Priority to EP04765899A priority patent/EP1673161A1/de
Publication of DE10347311A1 publication Critical patent/DE10347311A1/de
Withdrawn legal-status Critical Current

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    • BPERFORMING OPERATIONS; TRANSPORTING
    • B82NANOTECHNOLOGY
    • B82YSPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
    • B82Y30/00Nanotechnology for materials or surface science, e.g. nanocomposites
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01JCHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J19/00Chemical, physical or physico-chemical processes in general; Their relevant apparatus
    • B01J19/0046Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01LCHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
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    • GPHYSICS
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    • G01N35/10Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
    • G01N35/1065Multiple transfer devices
    • G01N35/1074Multiple transfer devices arranged in a two-dimensional array
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    • B01J2219/00306Reactor vessels in a multiple arrangement
    • B01J2219/00313Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
    • B01J2219/00315Microtiter plates
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    • B01J2219/00313Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
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    • B01J2219/00605Making arrays on substantially continuous surfaces the compounds being directly bound or immobilised to solid supports
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    • C40COMBINATORIAL TECHNOLOGY
    • C40BCOMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
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  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nanotechnology (AREA)
  • Organic Chemistry (AREA)
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  • Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Composite Materials (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Materials Engineering (AREA)
  • Condensed Matter Physics & Semiconductors (AREA)
  • Clinical Laboratory Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
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  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
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  • Pathology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)

Abstract

Die Erfindung betrifft eine Vorrichtung zur Durchführung von Reaktionen mit Reagenzmengen im Bereich von 0,5 bis 10 nmol, bei der die Reagenzien über Dosierstationen (5, 9, 11, 13) an Reaktionsorte (3) dosiert werden, die sich entlang einer Reaktionsstrecke (2) bewegen, wobei mindestens eine Dosierstation (5, 9, 11, 13) und eine Entnahmestelle (16) derart angeordnet sind, dass die Zeit, in der sich die Reaktionsorte (3) auf der Reaktionsstrecke (2) bewegen, mindestens der erforderlichen Reaktionszeit für einen Reaktionsschritt entspricht.
DE2003147311 2003-10-08 2003-10-08 Verfahren und Vorrichtung zur Durchführung von Reaktionen Withdrawn DE10347311A1 (de)

Priority Applications (3)

Application Number Priority Date Filing Date Title
DE2003147311 DE10347311A1 (de) 2003-10-08 2003-10-08 Verfahren und Vorrichtung zur Durchführung von Reaktionen
PCT/EP2004/011291 WO2005035110A1 (de) 2003-10-08 2004-10-08 Verfahren und vorrichtung zur durchführung von reaktionen
EP04765899A EP1673161A1 (de) 2003-10-08 2004-10-08 Verfahren und vorrichtung zur durchführung von reaktionen

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Application Number Priority Date Filing Date Title
DE2003147311 DE10347311A1 (de) 2003-10-08 2003-10-08 Verfahren und Vorrichtung zur Durchführung von Reaktionen

Publications (1)

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DE10347311A1 true DE10347311A1 (de) 2005-05-12

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DE2003147311 Withdrawn DE10347311A1 (de) 2003-10-08 2003-10-08 Verfahren und Vorrichtung zur Durchführung von Reaktionen

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EP (1) EP1673161A1 (de)
DE (1) DE10347311A1 (de)
WO (1) WO2005035110A1 (de)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114206891A (zh) * 2019-04-10 2022-03-18 日东电工艾维西亚有限公司 用于生物聚合物的顺序合成的方法和设备

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20050169816A1 (en) * 2003-12-15 2005-08-04 Kirshner Brian M. Automated oligomer synthesis
US8685750B2 (en) 2008-04-28 2014-04-01 Douglas Scientific, Llc. High throughput screening employing combination of dispensing well plate device and array tape
CA2906011A1 (en) 2013-03-15 2014-09-18 Douglas Scientific, LLC Reusable belt with a matrix of wells

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