DE10347311A1 - Verfahren und Vorrichtung zur Durchführung von Reaktionen - Google Patents
Verfahren und Vorrichtung zur Durchführung von Reaktionen Download PDFInfo
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- DE10347311A1 DE10347311A1 DE2003147311 DE10347311A DE10347311A1 DE 10347311 A1 DE10347311 A1 DE 10347311A1 DE 2003147311 DE2003147311 DE 2003147311 DE 10347311 A DE10347311 A DE 10347311A DE 10347311 A1 DE10347311 A1 DE 10347311A1
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B82—NANOTECHNOLOGY
- B82Y—SPECIFIC USES OR APPLICATIONS OF NANOSTRUCTURES; MEASUREMENT OR ANALYSIS OF NANOSTRUCTURES; MANUFACTURE OR TREATMENT OF NANOSTRUCTURES
- B82Y30/00—Nanotechnology for materials or surface science, e.g. nanocomposites
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J19/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J19/0046—Sequential or parallel reactions, e.g. for the synthesis of polypeptides or polynucleotides; Apparatus and devices for combinatorial chemistry or for making molecular arrays
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01L—CHEMICAL OR PHYSICAL LABORATORY APPARATUS FOR GENERAL USE
- B01L3/00—Containers or dishes for laboratory use, e.g. laboratory glassware; Droppers
- B01L3/02—Burettes; Pipettes
- B01L3/0241—Drop counters; Drop formers
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- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N35/00—Automatic analysis not limited to methods or materials provided for in any single one of groups G01N1/00 - G01N33/00; Handling materials therefor
- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N35/1065—Multiple transfer devices
- G01N35/1074—Multiple transfer devices arranged in a two-dimensional array
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
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- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
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- B01J2219/00313—Reactor vessels in a multiple arrangement the reactor vessels being formed by arrays of wells in blocks
- B01J2219/00315—Microtiter plates
- B01J2219/00317—Microwell devices, i.e. having large numbers of wells
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
- B01J2219/00274—Sequential or parallel reactions; Apparatus and devices for combinatorial chemistry or for making arrays; Chemical library technology
- B01J2219/00277—Apparatus
- B01J2219/00279—Features relating to reactor vessels
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- B01J2219/00324—Reactor vessels in a multiple arrangement the reactor vessels or wells being arranged in plates moving in parallel to each other
- B01J2219/00328—Movement by linear translation
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B—PERFORMING OPERATIONS; TRANSPORTING
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- B01J2219/00603—Making arrays on substantially continuous surfaces
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- B01J2219/00—Chemical, physical or physico-chemical processes in general; Their relevant apparatus
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
- C40B40/00—Libraries per se, e.g. arrays, mixtures
- C40B40/04—Libraries containing only organic compounds
- C40B40/06—Libraries containing nucleotides or polynucleotides, or derivatives thereof
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- C—CHEMISTRY; METALLURGY
- C40—COMBINATORIAL TECHNOLOGY
- C40B—COMBINATORIAL CHEMISTRY; LIBRARIES, e.g. CHEMICAL LIBRARIES
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- C40B40/04—Libraries containing only organic compounds
- C40B40/12—Libraries containing saccharides or polysaccharides, or derivatives thereof
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- C40B50/00—Methods of creating libraries, e.g. combinatorial synthesis
- C40B50/14—Solid phase synthesis, i.e. wherein one or more library building blocks are bound to a solid support during library creation; Particular methods of cleavage from the solid support
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- C40—COMBINATORIAL TECHNOLOGY
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- C40B60/00—Apparatus specially adapted for use in combinatorial chemistry or with libraries
- C40B60/14—Apparatus specially adapted for use in combinatorial chemistry or with libraries for creating libraries
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- G—PHYSICS
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- G01N35/10—Devices for transferring samples or any liquids to, in, or from, the analysis apparatus, e.g. suction devices, injection devices
- G01N2035/1027—General features of the devices
- G01N2035/1034—Transferring microquantities of liquid
- G01N2035/1037—Using surface tension, e.g. pins or wires
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- G—PHYSICS
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- G—PHYSICS
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- G01N35/1002—Reagent dispensers
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- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nanotechnology (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Physics & Mathematics (AREA)
- Health & Medical Sciences (AREA)
- General Physics & Mathematics (AREA)
- Composite Materials (AREA)
- Crystallography & Structural Chemistry (AREA)
- Materials Engineering (AREA)
- Condensed Matter Physics & Semiconductors (AREA)
- Clinical Laboratory Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Pathology (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
- Physical Or Chemical Processes And Apparatus (AREA)
Abstract
Die Erfindung betrifft eine Vorrichtung zur Durchführung von Reaktionen mit Reagenzmengen im Bereich von 0,5 bis 10 nmol, bei der die Reagenzien über Dosierstationen (5, 9, 11, 13) an Reaktionsorte (3) dosiert werden, die sich entlang einer Reaktionsstrecke (2) bewegen, wobei mindestens eine Dosierstation (5, 9, 11, 13) und eine Entnahmestelle (16) derart angeordnet sind, dass die Zeit, in der sich die Reaktionsorte (3) auf der Reaktionsstrecke (2) bewegen, mindestens der erforderlichen Reaktionszeit für einen Reaktionsschritt entspricht.
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2003147311 DE10347311A1 (de) | 2003-10-08 | 2003-10-08 | Verfahren und Vorrichtung zur Durchführung von Reaktionen |
PCT/EP2004/011291 WO2005035110A1 (de) | 2003-10-08 | 2004-10-08 | Verfahren und vorrichtung zur durchführung von reaktionen |
EP04765899A EP1673161A1 (de) | 2003-10-08 | 2004-10-08 | Verfahren und vorrichtung zur durchführung von reaktionen |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE2003147311 DE10347311A1 (de) | 2003-10-08 | 2003-10-08 | Verfahren und Vorrichtung zur Durchführung von Reaktionen |
Publications (1)
Publication Number | Publication Date |
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DE10347311A1 true DE10347311A1 (de) | 2005-05-12 |
Family
ID=34428320
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE2003147311 Withdrawn DE10347311A1 (de) | 2003-10-08 | 2003-10-08 | Verfahren und Vorrichtung zur Durchführung von Reaktionen |
Country Status (3)
Country | Link |
---|---|
EP (1) | EP1673161A1 (de) |
DE (1) | DE10347311A1 (de) |
WO (1) | WO2005035110A1 (de) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114206891A (zh) * | 2019-04-10 | 2022-03-18 | 日东电工艾维西亚有限公司 | 用于生物聚合物的顺序合成的方法和设备 |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20050169816A1 (en) * | 2003-12-15 | 2005-08-04 | Kirshner Brian M. | Automated oligomer synthesis |
US8685750B2 (en) | 2008-04-28 | 2014-04-01 | Douglas Scientific, Llc. | High throughput screening employing combination of dispensing well plate device and array tape |
CA2906011A1 (en) | 2013-03-15 | 2014-09-18 | Douglas Scientific, LLC | Reusable belt with a matrix of wells |
Citations (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5310674A (en) * | 1982-05-10 | 1994-05-10 | Bar-Ilan University | Apertured cell carrier |
WO1997019749A1 (en) * | 1995-11-27 | 1997-06-05 | Dehlinger Peter J | Method and apparatus for producing position-addressable combinatorial libraries |
WO2000040330A2 (de) * | 1998-12-30 | 2000-07-13 | Mwg - Biotech Ag | Vorrichtung zur durchführung von chemischen reaktionen |
DE60000539T2 (de) * | 1999-04-16 | 2003-03-06 | Pe Corp Ny Foster City | Vorrichtung und verfahren zur übertragung von kleinen substanzvolumen |
DE60000874T2 (de) * | 1999-02-16 | 2003-08-28 | Pe Corp Ny Foster City | Matrixsystem für aufbewahrung und abgabe |
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FR2353856A1 (fr) * | 1976-06-02 | 1977-12-30 | Chateau Guy | Ruban destine a servir de support a une reaction par exemple chimique ou biochimique, et procede d'analyse le mettant en oeuvre |
US5985214A (en) * | 1997-05-16 | 1999-11-16 | Aurora Biosciences Corporation | Systems and methods for rapidly identifying useful chemicals in liquid samples |
EP1181100A4 (de) * | 1999-05-03 | 2002-09-25 | Ljl Biosystems Inc | Integriertes probenbearbeitungssystem |
WO2001077640A2 (en) * | 2000-04-05 | 2001-10-18 | Alexion Pharmaceuticals, Inc. | Methods and devices for storing and dispensing liquids |
US6841663B2 (en) * | 2001-10-18 | 2005-01-11 | Agilent Technologies, Inc. | Chemical arrays |
-
2003
- 2003-10-08 DE DE2003147311 patent/DE10347311A1/de not_active Withdrawn
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2004
- 2004-10-08 WO PCT/EP2004/011291 patent/WO2005035110A1/de active Application Filing
- 2004-10-08 EP EP04765899A patent/EP1673161A1/de not_active Withdrawn
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US5310674A (en) * | 1982-05-10 | 1994-05-10 | Bar-Ilan University | Apertured cell carrier |
WO1997019749A1 (en) * | 1995-11-27 | 1997-06-05 | Dehlinger Peter J | Method and apparatus for producing position-addressable combinatorial libraries |
WO2000040330A2 (de) * | 1998-12-30 | 2000-07-13 | Mwg - Biotech Ag | Vorrichtung zur durchführung von chemischen reaktionen |
DE60000874T2 (de) * | 1999-02-16 | 2003-08-28 | Pe Corp Ny Foster City | Matrixsystem für aufbewahrung und abgabe |
DE60000539T2 (de) * | 1999-04-16 | 2003-03-06 | Pe Corp Ny Foster City | Vorrichtung und verfahren zur übertragung von kleinen substanzvolumen |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN114206891A (zh) * | 2019-04-10 | 2022-03-18 | 日东电工艾维西亚有限公司 | 用于生物聚合物的顺序合成的方法和设备 |
EP3953364A4 (de) * | 2019-04-10 | 2023-01-11 | NITTO DENKO Avecia Inc. | Verfahren und vorrichtung zur sequenziellen synthese von biologischen polymeren |
Also Published As
Publication number | Publication date |
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WO2005035110A1 (de) | 2005-04-21 |
EP1673161A1 (de) | 2006-06-28 |
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