DD298909A5 - Verfahren zur herstellung 8-substituierter 2-aminotetraline - Google Patents

Verfahren zur herstellung 8-substituierter 2-aminotetraline Download PDF

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Publication number
DD298909A5
DD298909A5 DD90340992A DD34099290A DD298909A5 DD 298909 A5 DD298909 A5 DD 298909A5 DD 90340992 A DD90340992 A DD 90340992A DD 34099290 A DD34099290 A DD 34099290A DD 298909 A5 DD298909 A5 DD 298909A5
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DD
German Democratic Republic
Prior art keywords
alkyl
aryl
hydrogen
dor
compound
Prior art date
Application number
DD90340992A
Other languages
German (de)
English (en)
Inventor
Nils-Erik Anden
Hoeoek Berit Ch E Backlund
Anna L M Bjoerk
Uli A Hacksell
Sven-Erik Hillver
Liu Ye
Eva Ch Mellin
Eva M Persson
Karl J Vallgarda
Yu Hong
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Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
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Publication of DD298909A5 publication Critical patent/DD298909A5/de

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/33Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings
    • C07C211/39Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton
    • C07C211/41Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems
    • C07C211/42Compounds containing amino groups bound to a carbon skeleton having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of an unsaturated carbon skeleton containing condensed ring systems with six-membered aromatic rings being part of the condensed ring systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00Drugs for disorders of the urinary system
    • A61P13/02Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/20Hypnotics; Sedatives
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/24Antidepressants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/26Psychostimulants, e.g. nicotine, ***e
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/28Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/20Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/46Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • C07C229/50Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino or carboxyl groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups and carboxyl groups bound to carbon atoms being part of the same condensed ring system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00Sulfonic acids; Halides, esters, or anhydrides thereof
    • C07C309/63Esters of sulfonic acids
    • C07C309/64Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms
    • C07C309/65Esters of sulfonic acids having sulfur atoms of esterified sulfo groups bound to acyclic carbon atoms of a saturated carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/02Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
    • C07D307/34Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D307/38Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D307/52Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/81Radicals substituted by nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2602/00Systems containing two condensed rings
    • C07C2602/02Systems containing two condensed rings the rings having only two atoms in common
    • C07C2602/04One of the condensed rings being a six-membered aromatic ring
    • C07C2602/10One of the condensed rings being a six-membered aromatic ring the other ring being six-membered, e.g. tetraline

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Reproductive Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Cardiology (AREA)
  • Anesthesiology (AREA)
  • Urology & Nephrology (AREA)
  • Endocrinology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyamides (AREA)
  • Purification Treatments By Anaerobic Or Anaerobic And Aerobic Bacteria Or Animals (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Saccharide Compounds (AREA)
DD90340992A 1989-05-26 1990-05-25 Verfahren zur herstellung 8-substituierter 2-aminotetraline DD298909A5 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8901889A SE8901889D0 (sv) 1989-05-26 1989-05-26 Novel 8-substituted-2-aminotetralines

Publications (1)

Publication Number Publication Date
DD298909A5 true DD298909A5 (de) 1992-03-19

Family

ID=20376074

Family Applications (1)

Application Number Title Priority Date Filing Date
DD90340992A DD298909A5 (de) 1989-05-26 1990-05-25 Verfahren zur herstellung 8-substituierter 2-aminotetraline

Country Status (41)

Country Link
US (1) US5635537A (sv)
EP (1) EP0399982B1 (sv)
JP (1) JP2818692B2 (sv)
KR (1) KR100193981B1 (sv)
CN (1) CN1023399C (sv)
AT (1) ATE129696T1 (sv)
AU (1) AU644081B2 (sv)
CA (1) CA2032498C (sv)
CY (1) CY1989A (sv)
CZ (1) CZ286038B6 (sv)
DD (1) DD298909A5 (sv)
DE (1) DE69023274T2 (sv)
DK (1) DK0399982T3 (sv)
DZ (1) DZ1417A1 (sv)
ES (1) ES2078962T3 (sv)
FI (1) FI114151B (sv)
GR (1) GR3018566T3 (sv)
HK (1) HK55697A (sv)
HR (1) HRP920622B1 (sv)
HU (2) HUT58685A (sv)
IE (1) IE75057B1 (sv)
IL (1) IL94428A (sv)
IS (1) IS1663B (sv)
JO (1) JO1617B1 (sv)
LT (1) LT3966B (sv)
LV (2) LV10243B (sv)
MX (1) MX20842A (sv)
NO (1) NO176603C (sv)
NZ (1) NZ233724A (sv)
PH (1) PH31110A (sv)
PL (2) PL165166B1 (sv)
PT (1) PT94163B (sv)
RU (1) RU2093507C1 (sv)
SA (1) SA90100274B1 (sv)
SE (1) SE8901889D0 (sv)
SI (1) SI9011006B (sv)
SK (1) SK280731B6 (sv)
UA (1) UA40562C2 (sv)
WO (1) WO1990014330A1 (sv)
YU (1) YU48830B (sv)
ZA (1) ZA903801B (sv)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUT61719A (en) * 1989-05-31 1993-03-01 Upjohn Co Process for producing 2-aminotetraline derivatives and pharmaceutical compositions comprising such compounds
CA2048846A1 (en) * 1990-08-15 1992-02-16 Craig Steven Hoechstetter Ring-substituted 2-amino-1,2,3,4-tetrahydronaphthalenes, 3-aminochromanes, and aminothiochromanes
US5643784A (en) * 1990-12-04 1997-07-01 H, Lundbeck A/S Indan derivatives
ES2102456T3 (es) * 1991-02-08 1997-08-01 Lilly Co Eli 3-amino-1,2,3,4-tetrahidronaftalenos sustituidos en el anillo.
US5244911A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz(cd)indoles and pharmaceutical use thereof
US5244912A (en) * 1991-03-28 1993-09-14 Eli Lilly And Company 6-heterocyclic-4-amino-1,3,4,5-tetrahydrobenz(cd)indoles and pharmaceutical use thereof
US5665744A (en) * 1991-03-28 1997-09-09 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2A,3,4,5-hexahydrobenzn [cd] indoles
US5347013A (en) * 1991-03-28 1994-09-13 Eli Lilly And Company 6-heterocyclic-4-amino-1,2,2a,3,4,5-hexahydrobenz[cd]indoles
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
SE9103745D0 (sv) * 1991-12-18 1991-12-18 Wikstroem Haakan Aryl-triflates and related compounds
DK78692D0 (da) * 1992-06-12 1992-06-12 Lundbeck & Co As H Dimere piperidin- og piperazinderivater
SE9301732D0 (sv) * 1993-05-18 1993-05-18 Haakan Wilhelm Wikstroem New centrally acting 5-,6-,7-, and 8-substituted sulphone esters of n-monosubstituted 2-aminotetralins
WO1996015099A1 (en) * 1994-11-09 1996-05-23 Novo Nordisk A/S Heterocyclic compounds, their preparation and use
GB9509156D0 (en) 1995-05-05 1995-06-28 Sandoz Ltd Organic compounds
WO2007081542A2 (en) * 2006-01-06 2007-07-19 Sepracor Inc. Tetralone-based monoamine reuptake inhibitors
BR112023017490A2 (pt) 2021-03-17 2023-11-07 Receptos Llc Métodos de tratamento de dermatite atópica com anticorpos anti il-13

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2752659A1 (de) * 1976-12-07 1978-06-08 Sandoz Ag Neue tetralinderivate, ihre herstellung und verwendung
US4247907A (en) * 1978-11-27 1981-01-27 International Business Machines Corporation Method and apparatus for typing characters and optically readable binary representations thereof on same page
SE8004002L (sv) * 1980-05-29 1981-11-30 Arvidsson Folke Lars Erik Terapeutiskt anvendbara tetralinderivat
IL65501A (en) * 1981-05-08 1986-04-29 Astra Laekemedel Ab 1-alkyl-2-aminotetralin derivatives,process for their preparation and pharmaceutical compositions containing them
DE3479314D1 (en) * 1984-05-22 1989-09-14 Nelson Res & Dev Substituted 2-aminotetralins and processes for synthesis
ATE38029T1 (de) * 1985-06-26 1988-11-15 Smithkline Beckman Corp Benz-trisubstituierte 2-aminotetraline.
IL79323A (en) * 1985-07-10 1990-03-19 Sanofi Sa Phenylethanolaminotetralines,their preparation and pharmaceutical compositions containing them
DE3718317A1 (de) * 1986-12-10 1988-06-16 Bayer Ag Substituierte basische 2-aminotetraline
DE3719924A1 (de) * 1986-12-22 1988-06-30 Bayer Ag 8-substituierte 2-aminotetraline
CA2026775C (en) * 1989-01-09 1998-04-07 Per Arvid Emil Carlsson Halo substituted aminotetralins
HUT61719A (en) * 1989-05-31 1993-03-01 Upjohn Co Process for producing 2-aminotetraline derivatives and pharmaceutical compositions comprising such compounds

Also Published As

Publication number Publication date
RU2093507C1 (ru) 1997-10-20
PT94163A (pt) 1991-01-08
US5635537A (en) 1997-06-03
EP0399982A1 (en) 1990-11-28
JPH04500362A (ja) 1992-01-23
CA2032498C (en) 2002-03-26
HRP920622B1 (en) 2000-04-30
FI114151B (sv) 2004-08-31
AU644081B2 (en) 1993-12-02
ZA903801B (en) 1991-01-30
IE901833L (en) 1990-11-26
HUT58685A (en) 1992-03-30
DK0399982T3 (da) 1996-03-04
PT94163B (pt) 1996-12-31
SA90100274B1 (ar) 2005-06-01
HU904810D0 (en) 1991-06-28
PL164245B1 (pl) 1994-07-29
IS1663B (is) 1997-07-04
DZ1417A1 (fr) 2004-09-13
NO910310D0 (no) 1991-01-25
PH31110A (en) 1998-02-23
JO1617B1 (en) 1991-11-27
LV10243A (lv) 1994-10-20
DE69023274T2 (de) 1996-04-11
IL94428A (en) 1995-12-31
MX20842A (es) 1993-11-01
LV11736A (lv) 1997-04-20
SE8901889D0 (sv) 1989-05-26
PL285330A1 (en) 1991-11-04
IE75057B1 (en) 1997-08-27
LT3966B (en) 1996-05-27
SK256090A3 (en) 2000-07-11
IS3580A7 (is) 1990-11-27
UA40562C2 (uk) 2001-08-15
FI910381A0 (fi) 1991-01-25
CA2032498A1 (en) 1990-11-27
CZ256090A3 (cs) 1999-10-13
YU100690A (en) 1992-05-28
HU211880A9 (en) 1995-12-28
HK55697A (en) 1997-05-09
DE69023274D1 (de) 1995-12-07
CY1989A (en) 1997-09-05
HRP920622A2 (en) 1998-06-30
LV11736B (en) 1997-10-20
LTIP1723A (en) 1995-08-25
AU5818590A (en) 1990-12-18
NZ233724A (en) 1993-01-27
SI9011006A (en) 1997-12-31
YU48830B (sh) 2002-03-18
NO910310L (no) 1991-01-25
GR3018566T3 (en) 1996-03-31
CN1023399C (zh) 1994-01-05
CZ286038B6 (cs) 1999-12-15
EP0399982B1 (en) 1995-11-02
NO176603C (no) 1995-05-03
LV10243B (en) 1995-04-20
JP2818692B2 (ja) 1998-10-30
ES2078962T3 (es) 1996-01-01
SK280731B6 (sk) 2000-07-11
NO176603B (no) 1995-01-23
IL94428A0 (en) 1991-03-10
KR920701121A (ko) 1992-08-11
WO1990014330A1 (en) 1990-11-29
KR100193981B1 (ko) 1999-06-15
SI9011006B (sl) 1998-12-31
PL165166B1 (pl) 1994-11-30
ATE129696T1 (de) 1995-11-15
CN1047494A (zh) 1990-12-05

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Expiry date: 20100526