CZ295472B6 - Eletriptan hydrobromid monohydrát, způsoby jeho přípravy a použití, farmaceutická kompozice s jeho obsahem a způsob přípravy bezvodého eletriptan hydrobromidu - Google Patents

Eletriptan hydrobromid monohydrát, způsoby jeho přípravy a použití, farmaceutická kompozice s jeho obsahem a způsob přípravy bezvodého eletriptan hydrobromidu Download PDF

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Publication number
CZ295472B6
CZ295472B6 CZ20011839A CZ20011839A CZ295472B6 CZ 295472 B6 CZ295472 B6 CZ 295472B6 CZ 20011839 A CZ20011839 A CZ 20011839A CZ 20011839 A CZ20011839 A CZ 20011839A CZ 295472 B6 CZ295472 B6 CZ 295472B6
Authority
CZ
Czechia
Prior art keywords
eletriptan hydrobromide
monohydrate
eletriptan
water
hydrobromide monohydrate
Prior art date
Application number
CZ20011839A
Other languages
Czech (cs)
English (en)
Other versions
CZ20011839A3 (cs
Inventor
Ian Christopher Dallman
Ronald James Ogilvie
Original Assignee
Pfizer Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc. filed Critical Pfizer Inc.
Publication of CZ20011839A3 publication Critical patent/CZ20011839A3/cs
Publication of CZ295472B6 publication Critical patent/CZ295472B6/cs

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/403—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with carbocyclic rings, e.g. carbazole
    • A61K31/404—Indoles, e.g. pindolol
    • A61K31/4045—Indole-alkylamines; Amides thereof, e.g. serotonin, melatonin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/14—Prodigestives, e.g. acids, enzymes, appetite stimulants, antidyspeptics, tonics, antiflatulents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/06—Antimigraine agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • A61P25/36—Opioid-abuse
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Addiction (AREA)
  • Pain & Pain Management (AREA)
  • Psychiatry (AREA)
  • Epidemiology (AREA)
  • Cardiology (AREA)
  • Obesity (AREA)
  • Child & Adolescent Psychology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Hospice & Palliative Care (AREA)
  • Otolaryngology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Electroluminescent Light Sources (AREA)
  • Lasers (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Indole Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
CZ20011839A 1998-11-27 1999-11-01 Eletriptan hydrobromid monohydrát, způsoby jeho přípravy a použití, farmaceutická kompozice s jeho obsahem a způsob přípravy bezvodého eletriptan hydrobromidu CZ295472B6 (cs)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GBGB9825988.0A GB9825988D0 (en) 1998-11-27 1998-11-27 Indole derivatives

Publications (2)

Publication Number Publication Date
CZ20011839A3 CZ20011839A3 (cs) 2001-10-17
CZ295472B6 true CZ295472B6 (cs) 2005-08-17

Family

ID=10843140

Family Applications (1)

Application Number Title Priority Date Filing Date
CZ20011839A CZ295472B6 (cs) 1998-11-27 1999-11-01 Eletriptan hydrobromid monohydrát, způsoby jeho přípravy a použití, farmaceutická kompozice s jeho obsahem a způsob přípravy bezvodého eletriptan hydrobromidu

Country Status (53)

Country Link
US (2) US20020013358A1 (fr)
EP (1) EP1135381B1 (fr)
JP (1) JP3777094B2 (fr)
KR (1) KR100413739B1 (fr)
CN (1) CN1131860C (fr)
AP (1) AP2001002149A0 (fr)
AR (1) AR024232A1 (fr)
AT (1) ATE273300T1 (fr)
AU (1) AU754731B2 (fr)
BG (1) BG64706B1 (fr)
BR (1) BR9915692A (fr)
CA (1) CA2352392C (fr)
CO (1) CO5150178A1 (fr)
CR (1) CR6325A (fr)
CU (1) CU23269A3 (fr)
CZ (1) CZ295472B6 (fr)
DE (1) DE69919388T2 (fr)
DK (1) DK1135381T3 (fr)
DZ (1) DZ2948A1 (fr)
EA (1) EA003551B1 (fr)
EE (1) EE04914B1 (fr)
ES (1) ES2224701T3 (fr)
GB (1) GB9825988D0 (fr)
GC (1) GC0000113A (fr)
GE (1) GEP20043183B (fr)
GT (1) GT199900202A (fr)
HK (1) HK1042898B (fr)
HN (1) HN1999000196A (fr)
HR (1) HRP20010398B1 (fr)
HU (1) HUP0105308A3 (fr)
ID (1) ID28802A (fr)
IL (1) IL141663A (fr)
IS (1) IS2238B (fr)
MA (1) MA26708A1 (fr)
MY (1) MY124078A (fr)
NO (1) NO320798B1 (fr)
NZ (1) NZ510055A (fr)
OA (1) OA11671A (fr)
PA (1) PA8485701A1 (fr)
PE (1) PE20001299A1 (fr)
PL (1) PL194503B1 (fr)
PT (1) PT1135381E (fr)
RS (1) RS50002B (fr)
SI (1) SI1135381T1 (fr)
SK (1) SK285774B6 (fr)
SV (1) SV1999000204A (fr)
TN (1) TNSN99221A1 (fr)
TR (1) TR200101493T2 (fr)
TW (1) TWI246512B (fr)
UA (1) UA68402C2 (fr)
UY (2) UY25823A1 (fr)
WO (1) WO2000032589A1 (fr)
ZA (1) ZA200102681B (fr)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB0018968D0 (en) * 2000-08-02 2000-09-20 Pfizer Ltd Particulate composition
EP1615635A1 (fr) 2003-04-11 2006-01-18 Pfizer Limited Combinaison pharmaceutique a base d'eletriptan et de bicarbonate de sodium
US6927296B2 (en) 2003-07-23 2005-08-09 Pfizer Inc. Process
GB0317229D0 (en) * 2003-07-23 2003-08-27 Pfizer Ltd Improved process
EP2093225A1 (fr) 2007-05-01 2009-08-26 Plus Chemicals B.V. Procédé de préparation de la forme ß de l'hydrobromide d'élétriptan crystallin
US20080319205A1 (en) * 2007-05-29 2008-12-25 Roman Bednar Process for preparing 5-bromo-3-[(R)-1-methyl-pyrrolidin-2-ylmethyl]-1H-indole
WO2009077858A2 (fr) * 2007-12-17 2009-06-25 Actavis Group Ptc Ehf Sel semioxalate innovant de l'élétriptan
US20120027816A1 (en) * 2009-02-25 2012-02-02 Actavis Group Ptc Ehf Highly pure eletriptan or a pharmaceutically acceptable salt thereof substantially free of eletriptan n-oxide impurity
WO2010116386A2 (fr) * 2009-04-08 2010-10-14 Biophore India Pharmaceuticals Pvt. Ltd. Nouveau polymorphe de bromhydrate d'életriptan et son procédé de fabrication
WO2011089614A1 (fr) * 2010-01-19 2011-07-28 Sms Pharmaceuticals Limited Procédé de préparation de bromhydrate d'élétriptan ayant une forme α
WO2014063752A1 (fr) 2012-10-26 2014-05-01 Synthon Bv Procédé de production de la forme cristalline alpha du bromhydrure d'élétriptan
CN103893112A (zh) * 2012-12-31 2014-07-02 重庆圣华曦药业股份有限公司 氢溴酸依来曲普坦注射液
CN107954947A (zh) * 2016-10-14 2018-04-24 北京莱瑞森医药科技有限公司 沃替西汀氢溴酸盐晶型c及其制备方法

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3952741A (en) * 1975-01-09 1976-04-27 Bend Research Inc. Controlled release delivery system by an osmotic bursting mechanism
FR2624732B1 (fr) * 1987-12-21 1991-02-15 Synthelabo Formulation pharmaceutique a liberation prolongee
US5474784A (en) * 1990-03-02 1995-12-12 British Technology Group Limited Dispensing device
US5545644A (en) * 1990-10-15 1996-08-13 Pfizer Inc. Indole derivatives
BR9106978A (pt) 1990-10-15 1993-09-28 Pfizer Derivados de indol
US5464633A (en) * 1994-05-24 1995-11-07 Jagotec Ag Pharmaceutical tablets releasing the active substance after a definite period of time
GB9417310D0 (en) * 1994-08-27 1994-10-19 Pfizer Ltd Therapeutic agents
GB9510223D0 (en) * 1995-05-20 1995-07-19 Pfizer Ltd Therapeutic agent
TW448172B (en) * 1996-03-08 2001-08-01 Pharmacia & Upjohn Co Llc Novel hydroxamic acid derivatives useful for the treatment of diseases related to connective tissue degradation
US5998462A (en) * 1996-12-16 1999-12-07 Allelix Biopharmaceuticals Inc. 5-alkyl indole compounds
GB9704498D0 (en) * 1997-03-05 1997-04-23 Glaxo Wellcome Spa Chemical compound
SI0999841T1 (fr) 1997-07-03 2001-12-31 Pfizer

Also Published As

Publication number Publication date
CU23269A3 (es) 2008-04-09
ID28802A (id) 2001-07-05
BG105539A (en) 2001-12-29
EP1135381B1 (fr) 2004-08-11
GC0000113A (en) 2005-06-29
SK285774B6 (sk) 2007-08-02
CN1131860C (zh) 2003-12-24
KR100413739B1 (ko) 2004-01-03
CZ20011839A3 (cs) 2001-10-17
BG64706B1 (bg) 2005-12-30
ES2224701T3 (es) 2005-03-01
AU754731B2 (en) 2002-11-21
UA68402C2 (en) 2004-08-16
YU18801A (sh) 2003-07-07
PL194503B1 (pl) 2007-06-29
CR6325A (fr) 2008-07-02
IS5868A (is) 2001-02-27
HRP20010398B1 (en) 2004-12-31
MY124078A (en) 2006-06-30
ATE273300T1 (de) 2004-08-15
EE04914B1 (et) 2007-10-15
NO20012584D0 (no) 2001-05-25
HK1042898A1 (en) 2002-08-30
SV1999000204A (es) 2000-10-16
EA003551B1 (ru) 2003-06-26
AR024232A1 (es) 2002-09-25
DZ2948A1 (fr) 2004-03-15
PL347928A1 (en) 2002-04-22
CA2352392A1 (fr) 2000-06-08
PT1135381E (pt) 2004-10-29
CO5150178A1 (es) 2002-04-29
PA8485701A1 (es) 2000-09-29
WO2000032589A1 (fr) 2000-06-08
AU6225399A (en) 2000-06-19
OA11671A (en) 2005-01-12
GEP20043183B (en) 2004-02-25
CA2352392C (fr) 2006-01-24
DK1135381T3 (da) 2004-11-15
ZA200102681B (en) 2002-07-02
DE69919388T2 (de) 2005-09-29
TR200101493T2 (tr) 2002-02-21
TNSN99221A1 (fr) 2005-11-10
CN1328554A (zh) 2001-12-26
GB9825988D0 (en) 1999-01-20
KR20010080594A (ko) 2001-08-22
JP3777094B2 (ja) 2006-05-24
HUP0105308A2 (hu) 2002-05-29
IL141663A (en) 2004-05-12
GT199900202A (es) 2001-05-19
BR9915692A (pt) 2001-08-14
DE69919388D1 (de) 2004-09-16
US20050131237A1 (en) 2005-06-16
PE20001299A1 (es) 2000-12-01
UY25823A1 (es) 2001-08-27
JP2002531449A (ja) 2002-09-24
NZ510055A (en) 2004-11-26
TWI246512B (en) 2006-01-01
SK6992001A3 (en) 2002-01-07
AP2001002149A0 (en) 2001-06-30
MA26708A1 (fr) 2004-12-20
HN1999000196A (es) 2005-11-26
EE200100285A (et) 2002-08-15
HUP0105308A3 (en) 2003-01-28
NO20012584L (no) 2001-07-27
UY25825A1 (es) 2000-08-21
RS50002B (sr) 2008-09-29
HK1042898B (zh) 2004-10-08
US7238723B2 (en) 2007-07-03
IS2238B (is) 2007-05-15
IL141663A0 (en) 2002-03-10
EA200100297A1 (ru) 2001-08-27
SI1135381T1 (en) 2004-10-31
US20020013358A1 (en) 2002-01-31
EP1135381A1 (fr) 2001-09-26
NO320798B1 (no) 2006-01-30
HRP20010398A2 (en) 2002-06-30

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MM4A Patent lapsed due to non-payment of fee

Effective date: 20081101