CY1746A - Antiviral guanine derivatives - Google Patents

Antiviral guanine derivatives

Info

Publication number: CY1746A
Authority: CY; Cyprus
Prior art keywords: guanine derivatives; antiviral; antiviral guanine; derivatives; guanine
Prior art date: 1983-08-18

Application number

CY174694A

Other languages

English (en)

Original Assignee

Beecham Group Plc

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1983-08-18

Filing date

1994-06-03

Publication date

1994-06-03

1983-08-18 Priority claimed from GB838322199A external-priority patent/GB8322199D0/en

1983-09-21 Priority claimed from GB838325271A external-priority patent/GB8325271D0/en

1984-03-30 Priority claimed from GB848408322A external-priority patent/GB8408322D0/en

1994-06-03 Application filed by Beecham Group Plc filed Critical Beecham Group Plc

1994-06-03 Publication of CY1746A publication Critical patent/CY1746A/xx

Links

230000000840 anti-viral effect Effects 0.000 title 1
UYTPUPDQBNUYGX-UHFFFAOYSA-N guanine Chemical class O=C1NC(N)=NC2=C1N=CN2 UYTPUPDQBNUYGX-UHFFFAOYSA-N 0.000 title 1

Classifications

- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C31/00—Saturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
- C07C31/18—Polyhydroxylic acyclic alcohols
- C07C31/22—Trihydroxylic alcohols, e.g. glycerol
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C43/00—Ethers; Compounds having groups, groups or groups
- C07C43/02—Ethers
- C07C43/03—Ethers having all ether-oxygen atoms bound to acyclic carbon atoms
- C07C43/14—Unsaturated ethers
- C07C43/178—Unsaturated ethers containing hydroxy or O-metal groups
- C07C43/1782—Unsaturated ethers containing hydroxy or O-metal groups containing six-membered aromatic rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C69/00—Esters of carboxylic acids; Esters of carbonic or haloformic acids
- C07C69/007—Esters of unsaturated alcohols having the esterified hydroxy group bound to an acyclic carbon atom
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D319/00—Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D319/04—1,3-Dioxanes; Hydrogenated 1,3-dioxanes
- C07D319/06—1,3-Dioxanes; Hydrogenated 1,3-dioxanes not condensed with other rings
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs

Landscapes

Chemical & Material Sciences (AREA)
Organic Chemistry (AREA)
Health & Medical Sciences (AREA)
Life Sciences & Earth Sciences (AREA)
Virology (AREA)
General Health & Medical Sciences (AREA)
Molecular Biology (AREA)
Communicable Diseases (AREA)
Medicinal Chemistry (AREA)
Veterinary Medicine (AREA)
Biochemistry (AREA)
Oncology (AREA)
Chemical Kinetics & Catalysis (AREA)
General Chemical & Material Sciences (AREA)
Public Health (AREA)
Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
Pharmacology & Pharmacy (AREA)
Animal Behavior & Ethology (AREA)
Engineering & Computer Science (AREA)
Biotechnology (AREA)
Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Heterocyclic Compounds That Contain Two Or More Ring Oxygen Atoms (AREA)

CY174694A 1983-08-18 1994-06-03 Antiviral guanine derivatives CY1746A (en)

Applications Claiming Priority (3)

Application Number	Priority Date	Filing Date	Title
GB838322199A GB8322199D0 (en)	1983-08-18	1983-08-18	Pharmaceutical composition
GB838325271A GB8325271D0 (en)	1983-09-21	1983-09-21	Compounds
GB848408322A GB8408322D0 (en)	1984-03-30	1984-03-30	Compounds

Publications (1)

Publication Number	Publication Date
CY1746A true CY1746A (en)	1994-06-03

Family

ID=27262187

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CY174694A CY1746A (en)	1983-08-18	1994-06-03	Antiviral guanine derivatives

Country Status (14)

Country	Link
US (3)	US5075445A (xx)
EP (1)	EP0141927B1 (xx)
JP (2)	JP2519882B2 (xx)
BG (1)	BG61325B2 (xx)
CA (1)	CA1339818C (xx)
CY (1)	CY1746A (xx)
CZ (1)	CZ283182B6 (xx)
DE (1)	DE3485225D1 (xx)
ES (3)	ES8602791A1 (xx)
GR (1)	GR80121B (xx)
HK (1)	HK126093A (xx)
IE (1)	IE58334B1 (xx)
MX (1)	MX160431A (xx)
NZ (1)	NZ209248A (xx)

Families Citing this family (75)

* Cited by examiner, † Cited by third party
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DE3485225D1 (de) *	1983-08-18	1991-12-05	Beecham Group Plc	Antivirale guanin-derivate.
US5684153A (en)	1984-08-16	1997-11-04	Beecham Group Plc	Process for the preparation of purine derivatives
IL73682A (en) *	1983-12-20	1991-08-16	Medivir Ab	Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation
EP0152316B1 (en) *	1984-01-26	1989-07-26	Merck & Co. Inc.	Substituted butyl guanines and their utilization in antiviral compositions
DE3582399D1 (de) *	1984-09-20	1991-05-08	Beecham Group Plc	Purin-derivate und ihre pharmazeutische verwendung.
GB8507606D0 (en)	1985-03-23	1985-05-01	Beecham Group Plc	Process
EP0216459B1 (en) *	1985-07-27	1990-05-16	Beecham Group Plc	9-substituted guanine monohydrates
GB8628826D0 (en) *	1986-12-02	1987-01-07	Beecham Group Plc	Pharmaceutical products
US5175288A (en) *	1987-08-01	1992-12-29	Beecham Group P.L.C.	Process for preparing purine derivatives and intermediates thereof
EP0302644B1 (en) *	1987-08-01	1997-01-29	Beecham Group Plc	Purine compounds and their preparation
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US6683084B1 (en)	1993-11-12	2004-01-27	Novartis International Pharmaceutical Ltd.	Use of 2-amino purine derivatives for the treatment and prophylaxis of human herpes virus 6 infections
GB9323404D0 (en) *	1993-11-12	1994-01-05	Smithkline Beecham Plc	Pharmaceuticals
GB9323403D0 (en) *	1993-11-12	1994-01-05	Smithkline Beecham Plc	Pharmaceuticals
GB9402161D0 (en) *	1994-02-04	1994-03-30	Wellcome Found	Chloropyrimidine intermediates
GB9407698D0 (en) *	1994-04-19	1994-06-15	Smithkline Beecham Plc	Pharmaceuticals
US5525606A (en) *	1994-08-01	1996-06-11	The United States Of America As Represented By The Department Of Health And Human Services	Substituted 06-benzylguanines and 6(4)-benzyloxypyrimidines
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CA2249598A1 (en) *	1996-03-26	1997-10-02	Paul Joseph Gilligan	Aryloxy- and arylthio-fused pyridines and pyrimidines and derivatives
GB9615253D0 (en) *	1996-07-20	1996-09-04	Smithkline Beecham Plc	Pharmaceuticals
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KR19980028023A (ko) *	1996-10-19	1998-07-15	김준웅	Ο-아실-ο-아미노산 9-(4-하이드록시-3-하이드록시메틸부트-1-일구아닌 에스테르 유도체
US6060458A (en) *	1998-02-13	2000-05-09	The United States Of America As Represented By The Department Of Health And Human Services	Oligodeoxyribonucleotides comprising O6 -benzylguanine and their use
GB9807116D0 (en) *	1998-04-02	1998-06-03	Smithkline Beecham Plc	Novel process
CN1666742A (zh) *	1998-11-02	2005-09-14	三角药物公司	对乙型肝炎病毒的联合治疗
US6407077B1 (en)	1998-11-05	2002-06-18	Emory University	β-L nucleosides for the treatment of HIV infection
US6107303A (en) *	1999-03-15	2000-08-22	Demarco; Charlene C.	Treatment of Epstein Barr infection
AUPQ806700A0 (en) *	2000-06-08	2000-07-06	Commonwealth Scientific And Industrial Research Organisation	Antiviral agents
CN102911166B (zh)	2001-03-01	2016-08-17	基利得科学公司	顺-ftc的多晶型物及其它晶型
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AU2006230269A1 (en)	2005-03-30	2006-10-05	Novartis Ag	Penciclovir or famciclovir for the treatment of recurrent genital herpes with a one-day application
GB2426247A (en) *	2005-05-20	2006-11-22	Arrow Int Ltd	Methods of preparing purine derivatives such as famciclovir
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JP2013527145A (ja)	2010-03-31	2013-06-27	ギリード・ファーマセット・エルエルシー	リン含有活性化剤の立体選択的合成
AU2013257951A1 (en)	2012-05-11	2015-01-22	Akron Molecules Ag	Use of compounds for the treatment of pain
US10342372B2 (en)	2012-07-27	2019-07-09	Anthony C. Farris	Combination bracket and garment hanger system and assembly mountable to an overhead trim piece associated with a doorway such as for rotatably supporting a garment during steam cleaning
US9474400B2 (en)	2012-07-27	2016-10-25	Anthony C. Farris	Combination bracket and garment hanger system and assembly mountable to an overhead trim piece associated with a doorway such as for rotatably supporting a garment during steam cleaning
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US4689129A (en) *	1985-07-16	1987-08-25	The Dow Chemical Company	Process for the preparation of submicron-sized titanium diboride
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1984
- 1984-08-10 DE DE8484109539T patent/DE3485225D1/de not_active Expired - Lifetime
- 1984-08-10 EP EP84109539A patent/EP0141927B1/en not_active Expired - Lifetime
- 1984-08-16 MX MX6893A patent/MX160431A/es unknown
- 1984-08-16 IE IE212384A patent/IE58334B1/en not_active IP Right Cessation
- 1984-08-16 CA CA000461212A patent/CA1339818C/en not_active Expired - Lifetime
- 1984-08-16 NZ NZ209248A patent/NZ209248A/en unknown
- 1984-08-16 GR GR80121A patent/GR80121B/el unknown
- 1984-08-17 ES ES535283A patent/ES8602791A1/es not_active Expired
- 1984-08-17 JP JP59171381A patent/JP2519882B2/ja not_active Expired - Lifetime
1985
- 1985-05-16 ES ES543214A patent/ES8603888A1/es not_active Expired
- 1985-05-16 ES ES543213A patent/ES8603887A1/es not_active Expired
1987
- 1987-08-12 US US07/085,216 patent/US5075445A/en not_active Expired - Lifetime
1991
- 1991-12-19 CZ CS913914A patent/CZ283182B6/cs unknown
1993
- 1993-09-08 JP JP5246065A patent/JP2543822B2/ja not_active Expired - Lifetime
- 1993-11-10 BG BG98210A patent/BG61325B2/bg unknown
- 1993-11-11 HK HK1260/93A patent/HK126093A/xx not_active IP Right Cessation
1994
- 1994-06-03 CY CY174694A patent/CY1746A/xx unknown
- 1994-09-23 US US08/311,291 patent/US6579981B1/en not_active Expired - Lifetime
- 1994-12-15 US US08/357,363 patent/US6573378B1/en not_active Expired - Fee Related

Also Published As

Publication number	Publication date
MX160431A (es)	1990-02-22
JPH06293764A (ja)	1994-10-21
DE3485225D1 (de)	1991-12-05
ES543213A0 (es)	1986-01-01
HK126093A (en)	1993-11-19
US5075445A (en)	1991-12-24
EP0141927A2 (en)	1985-05-22
IE842123L (en)	1985-02-18
IE58334B1 (en)	1993-09-08
JP2519882B2 (ja)	1996-07-31
CZ391491A3 (en)	1993-01-13
NZ209248A (en)	1988-01-08
ES543214A0 (es)	1986-01-01
ES8603887A1 (es)	1986-01-01
EP0141927B1 (en)	1991-10-30
CZ283182B6 (cs)	1998-01-14
GR80121B (en)	1984-12-17
US6573378B1 (en)	2003-06-03
CA1339818C (en)	1998-04-14
ES535283A0 (es)	1985-12-01
JP2543822B2 (ja)	1996-10-16
ES8603888A1 (es)	1986-01-01
ES8602791A1 (es)	1985-12-01
JPS6058982A (ja)	1985-04-05
US6579981B1 (en)	2003-06-17
BG61325B2 (bg)	1997-05-30
EP0141927A3 (en)	1986-03-12

Publication	Publication Date	Title
HK126093A (en)	1993-11-19	Antiviral guanine derivatives
PH23593A (en)	1989-09-11	Difluoronucleosides as antiviral agents
GB8431910D0 (en)	1985-01-30	Derivatives of guanine
GB8320308D0 (en)	1983-09-01	Antiviral combinations
DE3571985D1 (en)	1989-09-07	8-substituted guanine derivatives
PT83201A (en)	1986-09-01	Guanine derivatives
PT81293A (en)	1985-11-01	Purine derivatives
ZA843152B (en)	1984-12-24	Antiviral agents
GB2142025B (en)	1986-11-12	Pyrimidine derivatives
GB8702937D0 (en)	1987-03-18	Purine derivatives
DE3468322D1 (en)	1988-02-11	Antiviral agent
GB2150570B (en)	1987-04-08	Novel antiviral agents
GB2152508B (en)	1986-10-15	Pyrimidine derivatives
ZA857647B (en)	1986-05-28	Purine derivatives
SG114493G (en)	1994-01-21	Antiviral guanine derivatives
ZA866173B (en)	1988-04-27	Guanine derivatives
IE832296L (en)	1984-03-30	Guanine derivatives
IE831447L (en)	1983-12-21	Novel guanine derivatives
PH20944A (en)	1987-06-10	Antiviral guanine derivatives
ZA844744B (en)	1986-02-26	Antiviral agents
ZA848080B (en)	1985-06-26	Purine derivatives
IE812946L (en)	1982-06-22	Guanine derivatives
GB8320309D0 (en)	1983-09-01	Antiviral compounds
IE863242L (en)	1987-06-13	Guanine derivatives
IE862197L (en)	1987-02-16	Guanine derivatives