CY1118394T1 - Δισκια που περιεχουν τριϋδρικη υδροχλωρικη βαρντεναφιλη - Google Patents
Δισκια που περιεχουν τριϋδρικη υδροχλωρικη βαρντεναφιληInfo
- Publication number
- CY1118394T1 CY1118394T1 CY20161101342T CY161101342T CY1118394T1 CY 1118394 T1 CY1118394 T1 CY 1118394T1 CY 20161101342 T CY20161101342 T CY 20161101342T CY 161101342 T CY161101342 T CY 161101342T CY 1118394 T1 CY1118394 T1 CY 1118394T1
- Authority
- CY
- Cyprus
- Prior art keywords
- vardenafil
- hydrochloride
- tablets containing
- containing tridentate
- production
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/53—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with three nitrogens as the only ring hetero atoms, e.g. chlorazanil, melamine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2806—Coating materials
- A61K9/2833—Organic macromolecular compounds
- A61K9/286—Polysaccharides, e.g. gums; Cyclodextrin
- A61K9/2866—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2095—Tabletting processes; Dosage units made by direct compression of powders or specially processed granules, by eliminating solvents, by melt-extrusion, by injection molding, by 3D printing
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/28—Dragees; Coated pills or tablets, e.g. with film or compression coating
- A61K9/2893—Tablet coating processes
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Endocrinology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Reproductive Health (AREA)
- Gynecology & Obstetrics (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Abstract
Η εφεύρεση αναφέρεται σε μία μέθοδο για την παρασκευή φαρμακευτικών μέσων που περιέχουν υδροχλωρική βαρντεναφίλη, κατ' ουσίαν ως τριϋδρικό άλας σε στερεή μορφή, και σε φαρμακευτικά μέσα τα οποία μπορούν να ληφθούν, σύμφωνα με την μέθοδο αυτή.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10232113A DE10232113A1 (de) | 2002-07-16 | 2002-07-16 | Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel |
EP03763695A EP1523303B1 (de) | 2002-07-16 | 2003-07-03 | Vardenafil hydrochlorid trihydrat enthaltende arzneimittel und deren herstellungsverfahren |
Publications (1)
Publication Number | Publication Date |
---|---|
CY1118394T1 true CY1118394T1 (el) | 2017-06-28 |
Family
ID=29796385
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20121100233T CY1112460T1 (el) | 2002-07-16 | 2012-03-08 | Φαρμακευτικα μεσα που περιεχουν τριϋδρικη υδροχλωρικη βαρντεναφιλη και διεργασιες για την παρασκευη αυτων |
CY20161101342T CY1118394T1 (el) | 2002-07-16 | 2016-12-23 | Δισκια που περιεχουν τριϋδρικη υδροχλωρικη βαρντεναφιλη |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CY20121100233T CY1112460T1 (el) | 2002-07-16 | 2012-03-08 | Φαρμακευτικα μεσα που περιεχουν τριϋδρικη υδροχλωρικη βαρντεναφιλη και διεργασιες για την παρασκευη αυτων |
Country Status (32)
Country | Link |
---|---|
US (2) | US8273876B2 (el) |
EP (2) | EP1523303B1 (el) |
JP (2) | JP5173113B2 (el) |
KR (2) | KR20100137572A (el) |
CN (2) | CN1681481B (el) |
AT (1) | ATE538777T1 (el) |
AU (1) | AU2003249942B2 (el) |
BR (1) | BRPI0305559B8 (el) |
CA (2) | CA2805600C (el) |
CU (1) | CU23473B7 (el) |
CY (2) | CY1112460T1 (el) |
DE (1) | DE10232113A1 (el) |
DK (2) | DK2272505T3 (el) |
EC (1) | ECSP055541A (el) |
ES (2) | ES2609593T3 (el) |
HK (1) | HK1084019A1 (el) |
HR (3) | HRP20050143B1 (el) |
HU (1) | HUE032362T2 (el) |
IL (2) | IL166162A (el) |
LT (1) | LT2272505T (el) |
MA (1) | MA27320A1 (el) |
MX (1) | MXPA05000554A (el) |
NO (2) | NO335434B1 (el) |
NZ (1) | NZ537698A (el) |
PH (1) | PH12012501171A1 (el) |
PL (1) | PL223341B1 (el) |
PT (2) | PT1523303E (el) |
RU (1) | RU2349306C2 (el) |
SI (2) | SI2272505T1 (el) |
UA (1) | UA85542C2 (el) |
WO (1) | WO2004006894A1 (el) |
ZA (1) | ZA200500268B (el) |
Families Citing this family (24)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP2295436A1 (de) * | 1997-11-12 | 2011-03-16 | Bayer Schering Pharma AG | 2-Phenyl-substituierte Imidazotriazinone als Phosphodiesterase V Inhibitoren |
CA2449163C (en) * | 2001-05-09 | 2010-07-13 | Bayer Healthcare Ag | New use of 2-phenyl-substituted imidazotriazinones |
DE10232113A1 (de) | 2002-07-16 | 2004-01-29 | Bayer Ag | Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel |
DE102004023069A1 (de) * | 2004-05-11 | 2005-12-08 | Bayer Healthcare Ag | Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil |
DE102005001989A1 (de) * | 2005-01-15 | 2006-07-20 | Bayer Healthcare Ag | Intravenöse Formulierungen von PDE-Inhibitoren |
DE102005009241A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit kontrollierter Bioverfügbarkeit |
DE102005009240A1 (de) * | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften |
MX2008000087A (es) * | 2005-06-23 | 2008-03-18 | Schering Corp | Formulaciones orales rapidamente absorbentes de inhibidores de la fosfodiesterasa 5. |
WO2007010337A2 (de) * | 2005-07-15 | 2007-01-25 | Proxomed Medizintechnik Gmbh | Verwendung von phosphodiesterase typ 5-hemmern für die prävention und behandlung von adipositas, sowie abgabesysteme für dieselben |
KR20080056250A (ko) * | 2005-09-29 | 2008-06-20 | 바이엘 헬스케어 아게 | 비뇨기 장애의 치료를 위한 pde 억제제 및 이들의 조합 |
US7977478B2 (en) * | 2006-03-13 | 2011-07-12 | Dr. Reddy's Laboratories Limited | Polymorphic forms of vardenafil |
DE102007027067A1 (de) * | 2007-06-12 | 2008-12-18 | Ratiopharm Gmbh | Verfahren zur Herstellung eines Arzneimittels enthaltend Vardenafil Hydrochlorid Trihydrat |
CN101711153A (zh) * | 2007-06-13 | 2010-05-19 | 拜耳先灵制药股份公司 | 用于治疗听觉损伤的pde抑制剂 |
DE102007034741A1 (de) * | 2007-07-25 | 2009-01-29 | Siemens Ag | Elektrische Maschine mit Öffnungen im Lagerschildunterteil |
PL390079A1 (pl) | 2009-12-30 | 2011-07-04 | Zakłady Farmaceutyczne POLPHARMA Spółka Akcyjna | Sposób otrzymywania wardenafilu i jego izolacji jako soli z kwasem cytrynowym oraz krystaliczna postać tej soli |
CZ2011767A3 (cs) | 2011-11-24 | 2013-06-05 | Zentiva, K.S. | Zpusob prípravy a izolace solí vardenafilu s kyselinami |
CN103372014B (zh) * | 2012-04-26 | 2015-10-21 | 齐鲁制药有限公司 | 一种能快速溶出、稳定的盐酸伐地那非口服固体制剂及其制备方法 |
CZ307091B6 (cs) | 2012-09-14 | 2018-01-10 | Zentiva, K.S. | Stabilní farmaceutický přípravek obsahující Vardenafil hydrochlorid |
EP3043793B1 (en) * | 2013-11-19 | 2021-01-06 | Siga Technologies Inc. | Rehydration of micronized tecovirimat monohydrate |
US20160317542A1 (en) | 2013-12-09 | 2016-11-03 | Respira Therapeutics, Inc. | Pde5 inhibitor powder formulations and methods relating thereto |
PL223869B1 (pl) | 2013-12-16 | 2016-11-30 | Starogardzkie Zakłady Farm Polpharma Spółka Akcyjna | Sposób otrzymywania wardenafilu i jego soli |
CN111655229A (zh) | 2017-12-20 | 2020-09-11 | 卡里亚制药控股有限公司 | 包含伐地那非的薄膜制剂、其制备方法及其用途 |
JP7336241B2 (ja) * | 2019-04-02 | 2023-08-31 | 富士化学工業株式会社 | バルデナフィル含有錠剤の製造方法 |
CN110507626B (zh) * | 2019-09-19 | 2020-08-18 | 山东创新药物研发有限公司 | 一种稳定的盐酸伐地那非三水合物药物组合物的制备方法 |
Family Cites Families (115)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US2705715A (en) * | 1952-10-29 | 1955-04-05 | American Cyanamid Co | Purine compounds and methods of preparing the same |
GB790762A (en) | 1953-08-28 | 1958-02-19 | Arthur Poole | A hydrate of lignocaine hydrochloride and process for making it |
CH367510A (de) * | 1957-11-27 | 1963-02-28 | Ciba Geigy | Verfahren zur Herstellung neuer Sulfonamide |
GB1042471A (en) * | 1963-01-16 | 1966-09-14 | Ilford Ltd | Penta-azaindenes, their production and use in photographic emulsions |
GB1051734A (el) * | 1963-01-16 | |||
US3169129A (en) * | 1963-05-10 | 1965-02-09 | American Cyanamid Co | 2-ortho-hydroxy-phenyl-4-(3h)-quinazolinones |
USRE26565E (en) * | 1966-03-02 | 1969-04-29 | Table iii | |
GB1338235A (en) | 1970-12-15 | 1973-11-21 | May & Baker Ltd | Azapurinones |
GB1493685A (en) * | 1970-12-15 | 1977-11-30 | May & Baker Ltd | 8-azapurinones |
BE791025A (fr) * | 1971-11-19 | 1973-05-07 | Allen & Hanburys Ltd | Composes heterocycliques |
GB1457873A (en) | 1973-01-04 | 1976-12-08 | Allen & Hanburys Ltd | Imidazotriazines |
US4052390A (en) * | 1973-06-12 | 1977-10-04 | May & Baker Limited | Azapurinones |
US4060615A (en) * | 1976-02-18 | 1977-11-29 | Mead Johnson & Company | 2-Piperazinyl-6,7-dimethoxyquinazolines |
GB1561345A (en) * | 1976-10-22 | 1980-02-20 | May & Baker Ltd | 8 - azapuring - 6 - ones |
US4159330A (en) * | 1976-11-02 | 1979-06-26 | Carlo Erba S.P.A. | 2-Disubstituted phenyl-3,4-dihydro-4-oxo-quinazoline derivatives and process for their preparation |
GB1584461A (en) | 1977-03-25 | 1981-02-11 | Allen & Hanburys Ltd | Imidazotriazines imidazotriazinones and pharmaceutical compositions containing them |
DK109578A (da) | 1977-03-25 | 1978-09-26 | Allen & Hanburys Ltd | Fremgangsmaade til fremstilling af heterocycliske forbindelser |
US4308384A (en) | 1978-09-18 | 1981-12-29 | Glaxo Group Limited | Production of triazinones |
EP0054132B1 (de) * | 1980-12-12 | 1984-10-10 | Dr. Karl Thomae GmbH | Neue Pyrimidinone, ihre Herstellung und Arzneimittel mit einem Gehalt an diesen Stoffen |
US4431440A (en) * | 1981-02-20 | 1984-02-14 | American Cyanamid Company | Method to alter or control the development and/or the life cycle of various plant species |
JPS60246396A (ja) | 1984-05-22 | 1985-12-06 | Sankyo Co Ltd | 酵素阻害物質ジヒドロデスオキシグリゼオ−ル酸及びその塩類 |
US4666908A (en) * | 1985-04-05 | 1987-05-19 | Warner-Lambert Company | 5-Substituted pyrazolo[4,3-d]pyrimidine-7-ones and methods of use |
CA1303037C (en) | 1987-02-02 | 1992-06-09 | Smith Kline & French Laboratories Limited | Purinone derivatives as bronchodilators vasodilators and anti-allergic agents |
US5254571A (en) * | 1988-04-21 | 1993-10-19 | Smith Kline & French Laboratories Ltd. | Chemical compounds |
ES2058527T3 (es) * | 1988-06-16 | 1994-11-01 | Smith Kline French Lab | Derivados de pirimidina condensados procedimiento y compuestos intermedios para su preparacion y composiciones farmaceuticas que los contienen. |
GB8814352D0 (en) | 1988-06-16 | 1988-07-20 | Smith Kline French Lab | Chemical compounds |
US5075310A (en) * | 1988-07-01 | 1991-12-24 | Smith Kline & French Laboratories, Ltd. | Pyrimidone derivatives as bronchodilators |
US4923874A (en) * | 1988-07-21 | 1990-05-08 | G. D. Searle & Co. | Use of 8-azapurin-6-one derivatives for control of hypertension |
GB8817651D0 (en) * | 1988-07-25 | 1988-09-01 | Smith Kline French Lab | Chemical compounds |
GB8827988D0 (en) * | 1988-11-30 | 1989-01-05 | Smith Kline French Lab | Chemical compounds |
GB8928346D0 (en) | 1989-12-15 | 1990-02-21 | Smith Kline French Lab | Chemical compounds |
WO1991015194A1 (en) * | 1990-04-11 | 1991-10-17 | The Upjohn Company | Taste masking of ibuprofen by fluid bed coating |
GB9013750D0 (en) | 1990-06-20 | 1990-08-08 | Pfizer Ltd | Therapeutic agents |
US5250534A (en) * | 1990-06-20 | 1993-10-05 | Pfizer Inc. | Pyrazolopyrimidinone antianginal agents |
GB9114760D0 (en) | 1991-07-09 | 1991-08-28 | Pfizer Ltd | Therapeutic agents |
US5316906A (en) * | 1991-08-23 | 1994-05-31 | Molecular Probes, Inc. | Enzymatic analysis using substrates that yield fluorescent precipitates |
GB9119704D0 (en) | 1991-09-14 | 1991-10-30 | Pfizer Ltd | Therapeutic agents |
GB9121028D0 (en) | 1991-10-03 | 1991-11-13 | Pfizer Ltd | Therapeutic agents |
GB9126260D0 (en) | 1991-12-11 | 1992-02-12 | Pfizer Ltd | Therapeutic agents |
US5294612A (en) * | 1992-03-30 | 1994-03-15 | Sterling Winthrop Inc. | 6-heterocyclyl pyrazolo [3,4-d]pyrimidin-4-ones and compositions and method of use thereof |
IL105553A (en) | 1992-05-06 | 1998-01-04 | Janssen Pharmaceutica Inc | Solid dosage forms consisting of a porous network of matrix that releases a substance that dissipates rapidly in water |
US5734053A (en) | 1992-06-26 | 1998-03-31 | Pfizer Inc | Purinone antianginal agents |
GB9213623D0 (en) | 1992-06-26 | 1992-08-12 | Pfizer Ltd | Therapeutic agents |
GB9218322D0 (en) * | 1992-08-28 | 1992-10-14 | Pfizer Ltd | Therapeutic agents |
GB9301192D0 (en) | 1993-06-09 | 1993-06-09 | Trott Francis W | Flower shaped mechanised table |
GB9312210D0 (en) | 1993-06-14 | 1993-07-28 | Smithkline Beecham Plc | Chemical compounds |
GB9315017D0 (en) | 1993-07-20 | 1993-09-01 | Glaxo Lab Sa | Chemical compounds |
WO1995007267A1 (fr) | 1993-09-10 | 1995-03-16 | Eisai Co., Ltd. | Compose de quinazoline |
US6210714B1 (en) * | 1993-11-23 | 2001-04-03 | Euro-Celtique S.A. | Immediate release tablet cores of acetaminophen having sustained-release coating |
JPH07206857A (ja) * | 1993-12-28 | 1995-08-08 | Synthelabo Sa | アルフゾシン塩酸塩の二水和物 |
US6143746A (en) * | 1994-01-21 | 2000-11-07 | Icos Corporation | Tetracyclic cyclic GMP-specific phosphodiesterase inhibitors, process of preparation and use |
US5374053A (en) * | 1994-01-21 | 1994-12-20 | Heidelberger Druckmaschinen Ag | Device for changing the transport position of products |
US5556847A (en) * | 1994-10-27 | 1996-09-17 | Duquesne University Of The Holy Ghost | Methods of effecting memory enhancement mediated by steroid sulfatase inhibitors |
GB9423911D0 (en) | 1994-11-26 | 1995-01-11 | Pfizer Ltd | Therapeutic agents |
CN1080721C (zh) * | 1995-07-03 | 2002-03-13 | 旭化成株式会社 | 1-(5-异喹啉磺酰基)高哌嗪盐酸盐水合物 |
GB9514464D0 (en) | 1995-07-14 | 1995-09-13 | Glaxo Lab Sa | Medicaments |
TW438608B (en) * | 1995-08-02 | 2001-06-07 | Hisamitsu Pharmaceutical Co | A tablet containing anion exchange resin |
JP3182685B2 (ja) * | 1995-09-01 | 2001-07-03 | 北陸製薬株式会社 | 水和物結晶及びその製造方法 |
DE19540642A1 (de) | 1995-11-01 | 1997-05-07 | Stief Christian Georg Priv Doz | Verwendung von Inhibitoren der Phosphodiesterase bei der Behandlung von Prostataerkrankungen |
GB9612514D0 (en) | 1996-06-14 | 1996-08-14 | Pfizer Ltd | Novel process |
JP2001501207A (ja) * | 1996-09-24 | 2001-01-30 | イーライ・リリー・アンド・カンパニー | コーティングされた粒子製剤 |
US6548490B1 (en) * | 1997-10-28 | 2003-04-15 | Vivus, Inc. | Transmucosal administration of phosphodiesterase inhibitors for the treatment of erectile dysfunction |
EP2295436A1 (de) * | 1997-11-12 | 2011-03-16 | Bayer Schering Pharma AG | 2-Phenyl-substituierte Imidazotriazinone als Phosphodiesterase V Inhibitoren |
DE19812462A1 (de) | 1998-03-23 | 1999-09-30 | Bayer Ag | 2-[2-Ethoxy-5(4-ethyl-piperazin-1-sulfonyl) -phenyl]-5-methyl-7-prophyl-3H-imidazo[5,1-f][1,2,4]triazin-4-on Dihydrochlorid |
US6221402B1 (en) * | 1997-11-20 | 2001-04-24 | Pfizer Inc. | Rapidly releasing and taste-masking pharmaceutical dosage form |
EP0945134A1 (de) * | 1998-03-27 | 1999-09-29 | Boehringer Ingelheim Pharma KG | Neue galenische Zubereitungsformen von Meloxicam zur oralen Applikation |
GT199900061A (es) | 1998-05-15 | 2000-10-14 | Pfizer | Formulaciones farmaceuticas. |
DE19827640A1 (de) * | 1998-06-20 | 1999-12-23 | Bayer Ag | 7-Alkyl- und Cycloalkyl-substituierte Imidazotriazinone |
WO2000020033A1 (fr) | 1998-10-05 | 2000-04-13 | Eisai Co., Ltd. | Comprimes se delitant immediatement dans la cavite buccale |
FR2785538B1 (fr) | 1998-11-06 | 2004-04-09 | Prographarm Laboratoires | Comprime a delitement rapide perfectionne |
US6552024B1 (en) | 1999-01-21 | 2003-04-22 | Lavipharm Laboratories Inc. | Compositions and methods for mucosal delivery |
AU3574500A (en) | 1999-03-25 | 2000-10-16 | Yuhan Corporation | Rapidly disintegrable tablet for oral administration |
JP2001106674A (ja) * | 1999-05-13 | 2001-04-17 | Nikken Chem Co Ltd | 塩酸イピダクリン水和物の製造方法 |
IL137429A0 (en) | 1999-07-28 | 2001-07-24 | Pfizer Prod Inc | Methods and compsitions for treating diseases and conditions of the eye |
US6284270B1 (en) | 1999-08-04 | 2001-09-04 | Drugtech Corporation | Means for creating a mass having structural integrity |
DE19944161A1 (de) * | 1999-09-15 | 2001-03-22 | Bayer Ag | Neue Kombination zur Behandlung von sexueller Dysfunktion |
US6075028A (en) * | 1999-09-23 | 2000-06-13 | Graham; Richard | Method of treating Tourette's syndrome and related CNS disorders |
CA2323008C (en) * | 1999-10-11 | 2005-07-12 | Pfizer Inc. | Pharmaceutically active compounds |
GB9923968D0 (en) | 1999-10-11 | 1999-12-15 | Pfizer Ltd | Therapeutic agents |
TW200400821A (en) | 1999-11-02 | 2004-01-16 | Pfizer | Pharmaceutical composition (II) useful for treating or preventing pulmonary hypertension in a patient |
KR20020062770A (ko) | 1999-12-24 | 2002-07-29 | 바이엘 악티엔게젤샤프트 | 이미다조 1,3,5 트리아지논 및 그의 용도 |
US6362478B1 (en) * | 2000-02-14 | 2002-03-26 | General Electric Company | Radiation detector signal pulse clipping |
JP2004525857A (ja) * | 2000-04-19 | 2004-08-26 | ジョンズ・ホプキンス・ユニバーシティ | 胃腸疾患の予防および治療のための方法 |
WO2002005820A1 (en) | 2000-07-19 | 2002-01-24 | Lavipharm Laboratories, Inc. | Sildenafil citrate solid dispersions having high water solubility |
AU2001289751A1 (en) | 2000-08-01 | 2002-02-13 | Bayer Aktiengesellschaft | Selective pde 2 inhibitors, used as medicaments for improving cognition |
EP1330250B1 (en) * | 2000-10-30 | 2004-05-12 | Lupin Limited | Rapidly disintegrating sustained release cefuroxime axetil composition |
US20020091129A1 (en) | 2000-11-20 | 2002-07-11 | Mitradev Boolell | Treatment of premature ejaculation |
IN192750B (el) | 2000-12-15 | 2004-05-15 | Ranbaxy Lab Ltd | |
DE10063108A1 (de) | 2000-12-18 | 2002-06-20 | Bayer Ag | Verfahren zur Herstellung von Sulfonamid-substituierten Imidazotriazinonen |
AR032556A1 (es) | 2001-02-08 | 2003-11-12 | Pharmacia Corp | Medicamento de accion inmediata para el tratamiento de la disfuncion sexual |
DE60236850D1 (de) * | 2001-02-15 | 2010-08-12 | Mitsubishi Tanabe Pharma Corp | Tabletten, die in der mundhöhle schnell zerfallen |
FR2823668B1 (fr) | 2001-04-20 | 2004-02-27 | Ethypharm Lab Prod Ethiques | Comprimes effervescents orodispersibles |
CA2449163C (en) * | 2001-05-09 | 2010-07-13 | Bayer Healthcare Ag | New use of 2-phenyl-substituted imidazotriazinones |
ATE333269T1 (de) | 2001-05-10 | 2006-08-15 | Astellas Pharma Inc | In der mundhöhle schnell zerfallende tabletten und prozess zu deren herstellung |
DE20220604U1 (de) | 2001-07-27 | 2004-02-26 | Yamanouchi Pharmaceutical Co., Ltd. | Zusammensetzung, enthaltend feine Partikel zur Langzeitfreisetzung für schnell in der Mundhöhle zerfallende Tabletten |
FR2831820B1 (fr) | 2001-11-05 | 2004-08-20 | Ethypharm Sa | Comprime orodispersible presentant une grande homogeneite et son procede de preparation |
US7118765B2 (en) | 2001-12-17 | 2006-10-10 | Spi Pharma, Inc. | Co-processed carbohydrate system as a quick-dissolve matrix for solid dosage forms |
GB0204771D0 (en) | 2002-02-28 | 2002-04-17 | Phoqus Ltd | Fast disintegrating tablets |
US7939102B2 (en) * | 2002-06-07 | 2011-05-10 | Torrent Pharmaceuticals Ltd. | Controlled release formulation of lamotrigine |
DE10232113A1 (de) | 2002-07-16 | 2004-01-29 | Bayer Ag | Vardenafil Hydrochlorid Trihydrat enthaltende Arzneimittel |
SE0202365D0 (sv) | 2002-08-05 | 2002-08-05 | Pharmacia Ab | New formulation and use thereof |
GB0219516D0 (en) | 2002-08-21 | 2002-10-02 | Phoqus Ltd | Fast dissolving and taste masked oral dosage form comprising sildenafil |
US8263126B2 (en) | 2003-06-06 | 2012-09-11 | Ethypharm | Orally-dispersible multilayer tablet |
DE10325813B4 (de) * | 2003-06-06 | 2007-12-20 | Universitätsklinikum Freiburg | Prophylaxe und/oder Therapie bei der portalen Hypertonie |
US6980922B2 (en) * | 2003-10-09 | 2005-12-27 | Computational Biodynamics, Llc | Computer simulation model for determining damage to the human central nervous system |
JP3841804B2 (ja) | 2003-10-15 | 2006-11-08 | 富士化学工業株式会社 | 口腔内速崩壊性錠剤用の組成物 |
MXPA06012564A (es) | 2004-04-27 | 2007-01-31 | Medicinova Inc | Derivados de acido fenoxialquilcarboxilico en el tratamiento de enfermedades inflamatorias. |
DE102004023069A1 (de) | 2004-05-11 | 2005-12-08 | Bayer Healthcare Ag | Neue Darreichungsformen des PDE 5-Inhibitors Vardenafil |
US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
NZ709754A (en) | 2004-10-21 | 2017-02-24 | Adare Pharmaceuticals Inc | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
US20060105038A1 (en) | 2004-11-12 | 2006-05-18 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions prepared by coacervation |
EP1817009A2 (en) | 2004-11-24 | 2007-08-15 | Spi Pharma, Inc. | Orally disintegrating compositions |
DE102005009240A1 (de) | 2005-03-01 | 2006-09-07 | Bayer Healthcare Ag | Arzneiformen mit verbesserten pharmakokinetischen Eigenschaften |
MX2008000087A (es) | 2005-06-23 | 2008-03-18 | Schering Corp | Formulaciones orales rapidamente absorbentes de inhibidores de la fosfodiesterasa 5. |
WO2007029376A1 (ja) | 2005-09-02 | 2007-03-15 | Fuji Chemical Industry Co., Ltd. | 口腔内速崩壊性錠剤 |
-
2002
- 2002-07-16 DE DE10232113A patent/DE10232113A1/de not_active Withdrawn
-
2003
- 2003-07-03 CA CA2805600A patent/CA2805600C/en not_active Expired - Lifetime
- 2003-07-03 CN CN038211440A patent/CN1681481B/zh not_active Expired - Lifetime
- 2003-07-03 DK DK10183693.0T patent/DK2272505T3/en active
- 2003-07-03 PL PL374694A patent/PL223341B1/pl unknown
- 2003-07-03 DK DK03763695.8T patent/DK1523303T3/da active
- 2003-07-03 US US10/521,534 patent/US8273876B2/en active Active
- 2003-07-03 CN CN201010289313.5A patent/CN102210689B/zh not_active Expired - Fee Related
- 2003-07-03 PT PT03763695T patent/PT1523303E/pt unknown
- 2003-07-03 CA CA2492747A patent/CA2492747C/en not_active Expired - Lifetime
- 2003-07-03 LT LTEP10183693.0T patent/LT2272505T/lt unknown
- 2003-07-03 KR KR1020107025930A patent/KR20100137572A/ko not_active Application Discontinuation
- 2003-07-03 MX MXPA05000554A patent/MXPA05000554A/es active IP Right Grant
- 2003-07-03 WO PCT/EP2003/007093 patent/WO2004006894A1/de active Application Filing
- 2003-07-03 HU HUE10183693A patent/HUE032362T2/en unknown
- 2003-07-03 AU AU2003249942A patent/AU2003249942B2/en not_active Expired
- 2003-07-03 KR KR1020137031758A patent/KR101552418B1/ko active IP Right Grant
- 2003-07-03 AT AT03763695T patent/ATE538777T1/de active
- 2003-07-03 RU RU2005103820/15A patent/RU2349306C2/ru active
- 2003-07-03 SI SI200332508A patent/SI2272505T1/sl unknown
- 2003-07-03 ES ES10183693.0T patent/ES2609593T3/es not_active Expired - Lifetime
- 2003-07-03 PT PT101836930T patent/PT2272505T/pt unknown
- 2003-07-03 EP EP03763695A patent/EP1523303B1/de not_active Revoked
- 2003-07-03 ES ES03763695T patent/ES2378358T3/es not_active Expired - Lifetime
- 2003-07-03 SI SI200332114T patent/SI1523303T1/sl unknown
- 2003-07-03 BR BRPI0305559A patent/BRPI0305559B8/pt active IP Right Grant
- 2003-07-03 JP JP2004520469A patent/JP5173113B2/ja not_active Expired - Lifetime
- 2003-07-03 EP EP10183693.0A patent/EP2272505B1/de not_active Expired - Lifetime
- 2003-07-03 NZ NZ537698A patent/NZ537698A/en not_active IP Right Cessation
- 2003-07-03 UA UAA200501444A patent/UA85542C2/ru unknown
-
2005
- 2005-01-05 IL IL166162A patent/IL166162A/en active IP Right Grant
- 2005-01-13 CU CU20050009A patent/CU23473B7/es unknown
- 2005-01-13 MA MA28039A patent/MA27320A1/fr unknown
- 2005-01-14 EC EC2005005541A patent/ECSP055541A/es unknown
- 2005-02-02 NO NO20050578A patent/NO335434B1/no not_active IP Right Cessation
- 2005-02-15 HR HRP20050143AA patent/HRP20050143B1/hr not_active IP Right Cessation
-
2006
- 2006-01-12 ZA ZA200500268A patent/ZA200500268B/en unknown
- 2006-04-04 HK HK06104147.8A patent/HK1084019A1/xx not_active IP Right Cessation
-
2012
- 2012-03-08 CY CY20121100233T patent/CY1112460T1/el unknown
- 2012-05-16 HR HRP20120418AA patent/HRP20120418B1/hr not_active IP Right Cessation
- 2012-06-11 PH PH12012501171A patent/PH12012501171A1/en unknown
- 2012-09-24 US US13/625,481 patent/US8841446B2/en not_active Expired - Lifetime
- 2012-10-30 JP JP2012239424A patent/JP2013063982A/ja active Pending
-
2013
- 2013-10-23 HR HRP20131002AA patent/HRP20131002A2/hr not_active Application Discontinuation
-
2014
- 2014-05-11 IL IL232538A patent/IL232538A0/en unknown
- 2014-10-24 NO NO20141272A patent/NO337043B1/no not_active IP Right Cessation
-
2016
- 2016-12-23 CY CY20161101342T patent/CY1118394T1/el unknown
Also Published As
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CY1118394T1 (el) | Δισκια που περιεχουν τριϋδρικη υδροχλωρικη βαρντεναφιλη | |
PT1534237E (pt) | Pastilhas de desintegração oral e processo para a sua obtenção | |
ATE323478T1 (de) | Pharmazeutische pellets enthaltend tamsulosin sowie deren herstellungsverfahren | |
AU2003221270A8 (en) | Nanocomposites: products, process for obtaining them and uses thereof | |
MX270158B (es) | Produccion de un producto de fermentacion. | |
NO20052997D0 (no) | Celluloseprodukt og fremgangsmate for dets produksjon. | |
ZA200409381B (en) | Ring-substituted diphenyl azetidones, method for the production thereof, medicaments containing said compounds, and use thereof | |
ES2171713T3 (es) | Metodo para producir tabletas mediante prensado y tabletas producidas por este metodo. | |
IL152374A0 (en) | A method of fabricating coded particles | |
WO2004014337A3 (en) | A process for the preparation of dispersible tablet of cephalexin | |
WO2004078108A3 (fr) | Comprime de fenofibrate et procede de fabrication | |
DE502004005702D1 (en) | 4-cyclohexyl-2-butanol als riechstoff | |
DE10346841A1 (de) | Vorrichtung zum Einsortieren von Gegenständen, insbesondere von pharmazeutischen Produkten wie Tabletten oder ähnlichem in Näpfe einer Packstoffbahn | |
WO2004008835A3 (en) | Method for treating cereal material with a screw transporter | |
HUP0401417A2 (en) | Pharmaceutical composition having in creased activity for preventing and/or treating gastro-intestinal illnesses and process for its preparation | |
RU2003116221A (ru) | Лекарственное средство и способ профилактического лечения первичной дисменореи | |
AU2003212315A1 (en) | Sourdough-based skin medication and skin care product, and production method | |
FI20020444A (fi) | Menetelmä ohuiden funktionaalisten kuparikalvojen valmistamiseksi elektorolyyttisesti ja menetelmällä valmistettu tuote | |
HUP0501127A2 (en) | Pharmaceutical and food compositions for influencing expression of genes, and process for producing them | |
FR2844218B1 (fr) | Procede de traitement chimique d'un substrat notamment en bois. | |
ITPR20020007A1 (it) | Recipiente predosato di prodotto medicinale e procedimento di realizzazione. | |
ZA200306184B (en) | A new product for the fight against ticks and the process for the production. | |
AU2003298203A1 (en) | Medicaments containing substituted 2,5-diaminomethyl-1h-pyrroles | |
ZA200105202B (en) | Plant care product applicable by spray methods and process for the manufacture of said product. | |
SI1824349T1 (sl) | Proizvodni postopek za izdelavo dietetskega proizvoda - oralnih tablet, ki vsebujejo ÄŤebalji kruh in vitamin C |