CY1117881T1 - Στερεες φαρμακευτικες συνθεσεις που περιλαμβανουν παραγωγα βιοπτερινης και χρησεις αυτων των συνθεσεων - Google Patents
Στερεες φαρμακευτικες συνθεσεις που περιλαμβανουν παραγωγα βιοπτερινης και χρησεις αυτων των συνθεσεωνInfo
- Publication number
- CY1117881T1 CY1117881T1 CY20161100768T CY161100768T CY1117881T1 CY 1117881 T1 CY1117881 T1 CY 1117881T1 CY 20161100768 T CY20161100768 T CY 20161100768T CY 161100768 T CY161100768 T CY 161100768T CY 1117881 T1 CY1117881 T1 CY 1117881T1
- Authority
- CY
- Cyprus
- Prior art keywords
- solid pharmaceutical
- pharmaceutical compositions
- compositions
- biopterine
- producers
- Prior art date
Links
- 239000008194 pharmaceutical composition Substances 0.000 title abstract 4
- 239000007787 solid Substances 0.000 title abstract 4
- 239000000203 mixture Substances 0.000 title abstract 2
- LHQIJBMDNUYRAM-AWFVSMACSA-N D-erythro-biopterin Chemical class N1=C(N)NC(=O)C2=NC([C@H](O)[C@H](O)C)=CN=C21 LHQIJBMDNUYRAM-AWFVSMACSA-N 0.000 abstract 1
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 239000004480 active ingredient Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 238000004108 freeze drying Methods 0.000 abstract 1
- 238000001990 intravenous administration Methods 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 235000021317 phosphate Nutrition 0.000 abstract 1
- 150000003013 phosphoric acid derivatives Chemical class 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/4985—Pyrazines or piperazines ortho- or peri-condensed with heterocyclic ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/02—Inorganic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/08—Solutions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/10—Dispersions; Emulsions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/19—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles lyophilised, i.e. freeze-dried, solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2300/00—Mixtures or combinations of active ingredients, wherein at least one active ingredient is fully defined in groups A61K31/00 - A61K41/00
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Dermatology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
Η παρούσα εφεύρεση σχετίζεται με στερεές φαρμακευτικές συνθέσεις που περιλαμβάνουν παράγωγα βιοπτερίνης όπως επίσης και με μεθόδους για λήψη αυτών των στερεών φαρμακευτικών συνθέσεων. Οι συνθέσεις περιέχουν το δραστικό συστατικό και φωσφορικά. Μπορούν να ληφθούν με λυοφιλίωση και να ανασυσταθούν για ενδοφλέβια χορήγηση. Η εφεύρεση επίσης σχετίζεται με τις στερεές φαρμακευτικές συνθέσεις της εφεύρεσης για αντιμετώπιση νόσων.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP14162727.3A EP2926805B1 (en) | 2014-03-31 | 2014-03-31 | Solid pharmaceutical compositions comprising biopterin derivatives and uses of such compositions |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CY1117881T1 true CY1117881T1 (el) | 2018-03-07 |
Family
ID=50389975
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CY20161100768T CY1117881T1 (el) | 2014-03-31 | 2016-08-04 | Στερεες φαρμακευτικες συνθεσεις που περιλαμβανουν παραγωγα βιοπτερινης και χρησεις αυτων των συνθεσεων |
Country Status (29)
| Country | Link |
|---|---|
| US (6) | US9895372B2 (el) |
| EP (2) | EP2926805B1 (el) |
| JP (3) | JP6552515B2 (el) |
| KR (1) | KR102374500B1 (el) |
| CN (2) | CN113521017A (el) |
| AU (2) | AU2015239736B2 (el) |
| CA (1) | CA2938267C (el) |
| CL (1) | CL2016002463A1 (el) |
| CY (1) | CY1117881T1 (el) |
| DK (1) | DK2926805T3 (el) |
| ES (1) | ES2586945T3 (el) |
| HK (1) | HK1213195A1 (el) |
| HR (1) | HRP20160802T1 (el) |
| HU (1) | HUE030221T2 (el) |
| IL (1) | IL248090B (el) |
| MX (1) | MX2016012784A (el) |
| MY (1) | MY180844A (el) |
| PE (1) | PE20161253A1 (el) |
| PH (1) | PH12016501519B1 (el) |
| PL (1) | PL2926805T3 (el) |
| PT (1) | PT2926805T (el) |
| RS (1) | RS54973B1 (el) |
| RU (1) | RU2694368C2 (el) |
| SA (1) | SA516371933B1 (el) |
| SG (1) | SG11201606151SA (el) |
| SI (1) | SI2926805T1 (el) |
| SM (1) | SMT201600246B (el) |
| WO (1) | WO2015150294A1 (el) |
| ZA (1) | ZA201605271B (el) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RS54973B1 (sr) | 2014-03-31 | 2016-11-30 | Vasopharm Gmbh | Čvrste farmaceutske kompozicije koje uključuju derivate biopterina i upotreba takvih kompozicija |
| JP2016168783A (ja) * | 2015-03-13 | 2016-09-23 | 株式会社東芝 | 記録装置、記録方法、及び記録媒体 |
| JP2020532535A (ja) * | 2017-09-01 | 2020-11-12 | ピーティーシー セラピューティクス エムピー，インコーポレイテッド | セピアプテリンを含む医薬組成物及びその使用 |
| JP6565103B2 (ja) * | 2017-09-06 | 2019-08-28 | 株式会社昭和冷凍プラント | 香気成分含有水溶液を含む液状製品の製造方法 |
| KR20220070477A (ko) * | 2019-09-25 | 2022-05-31 | 피티씨 테라퓨틱스 엠피, 인크. | 고페닐알라닌혈증 치료 방법 |
| CA3235704A1 (en) | 2021-12-03 | 2023-06-08 | Verinos Operations Gmbh | Methods of treating patients suffering from brain injury and methods of increasing the value of the extended glasgow outcome scale of patients suffering from brain injury |
| TW202406555A (zh) | 2022-05-06 | 2024-02-16 | 德商ｖｅｒｉＮＯＳ運營有限公司 | 治療患有與增加的麩胺酸水平相關的疾病狀況或病症的患者的方法 |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5922713A (en) * | 1997-06-26 | 1999-07-13 | Werner; Ernst | Inhibition of nitric oxide synthase |
| EP0906913B1 (de) | 1997-10-06 | 2001-05-23 | Ernst Werner | Pteridinderivate als NO Synthase-Hemmer |
| US6803046B2 (en) * | 2002-08-16 | 2004-10-12 | Bracco International B.V. | Sincalide formulations |
| WO2005037286A1 (en) * | 2003-03-25 | 2005-04-28 | Vasopharm Biotech Gmbh | Use of pteridine derivatives for the treatment of increased intracranial pressure and secondary ischemia |
| AU2004311544A1 (en) * | 2003-11-17 | 2005-07-21 | Merck & Cie | Crystalline forms of (6R) -L-erythro-tetrahydrobiopterin dihydrochloride |
| DK1757293T3 (da) * | 2004-05-11 | 2012-10-22 | Daiichi Sankyo Co Ltd | Bh4-responsiv hyperphenylalaninæmi-medikamenter |
| SE0401826D0 (sv) | 2004-07-09 | 2004-07-09 | Trimble Ab | Method of preparing a winding for an n-phase motor |
| MX2007005039A (es) * | 2004-11-17 | 2007-06-19 | Biomarin Pharm Inc | Formulacion de tableta estable. |
| EP1669355A1 (en) * | 2004-12-02 | 2006-06-14 | Vasopharm Biotech GmbH | Aminotetrahydropteridines and processes for manufacture thereof |
| DK2139485T3 (da) * | 2007-04-11 | 2013-01-21 | Biomarin Pharm Inc | Fremgangsmåder til admistration af tetrahydrobiopterin, associerede sammensætninger, og fremgangsmåder til måling |
| CN101658067B (zh) | 2007-04-24 | 2012-06-27 | 欧司朗股份有限公司 | 用于点燃和驱动放电灯的电路装置 |
| WO2010017570A2 (de) * | 2008-08-12 | 2010-02-18 | Orpha Swiss Gmbh | Pharmazeutische darreichungsform enthaltend tetrahydrobiopterin |
| CN103458900A (zh) * | 2011-03-01 | 2013-12-18 | 鲁必康研究私人有限公司 | 四氢生物蝶呤的稳定组合物 |
| EP2750664A1 (en) * | 2011-08-30 | 2014-07-09 | Fresenius Kabi USA, LLC | Levothyroxine formulations |
| RS54973B1 (sr) * | 2014-03-31 | 2016-11-30 | Vasopharm Gmbh | Čvrste farmaceutske kompozicije koje uključuju derivate biopterina i upotreba takvih kompozicija |
-
2014
- 2014-03-31 RS RS20160595A patent/RS54973B1/sr unknown
- 2014-03-31 PL PL14162727.3T patent/PL2926805T3/pl unknown
- 2014-03-31 ES ES14162727.3T patent/ES2586945T3/es active Active
- 2014-03-31 SI SI201430042A patent/SI2926805T1/sl unknown
- 2014-03-31 HU HUE14162727A patent/HUE030221T2/en unknown
- 2014-03-31 DK DK14162727.3T patent/DK2926805T3/en active
- 2014-03-31 PT PT141627273T patent/PT2926805T/pt unknown
- 2014-03-31 EP EP14162727.3A patent/EP2926805B1/en active Active
-
2015
- 2015-03-30 JP JP2016556270A patent/JP6552515B2/ja active Active
- 2015-03-30 CA CA2938267A patent/CA2938267C/en active Active
- 2015-03-30 MY MYPI2016702995A patent/MY180844A/en unknown
- 2015-03-30 AU AU2015239736A patent/AU2015239736B2/en active Active
- 2015-03-30 RU RU2016141449A patent/RU2694368C2/ru active
- 2015-03-30 MX MX2016012784A patent/MX2016012784A/es unknown
- 2015-03-30 CN CN202110640860.1A patent/CN113521017A/zh active Pending
- 2015-03-30 WO PCT/EP2015/056824 patent/WO2015150294A1/en active Application Filing
- 2015-03-30 US US14/913,665 patent/US9895372B2/en active Active
- 2015-03-30 KR KR1020167025896A patent/KR102374500B1/ko active IP Right Grant
- 2015-03-30 CN CN201580017915.6A patent/CN106572976A/zh active Pending
- 2015-03-30 PE PE2016001818A patent/PE20161253A1/es unknown
- 2015-03-30 SG SG11201606151SA patent/SG11201606151SA/en unknown
- 2015-03-30 EP EP15715697.7A patent/EP3125864A1/en not_active Withdrawn
-
2016
- 2016-02-03 HK HK16101231.9A patent/HK1213195A1/zh unknown
- 2016-07-06 HR HRP20160802TT patent/HRP20160802T1/hr unknown
- 2016-07-26 SM SM201600246T patent/SMT201600246B/it unknown
- 2016-07-29 ZA ZA2016/05271A patent/ZA201605271B/en unknown
- 2016-08-01 PH PH12016501519A patent/PH12016501519B1/en unknown
- 2016-08-04 CY CY20161100768T patent/CY1117881T1/el unknown
- 2016-09-27 IL IL24809016A patent/IL248090B/en active IP Right Grant
- 2016-09-27 SA SA516371933A patent/SA516371933B1/ar unknown
- 2016-09-29 CL CL2016002463A patent/CL2016002463A1/es unknown
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2017
- 2017-05-02 US US15/584,890 patent/US10016431B2/en active Active
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2018
- 2018-06-08 US US16/003,374 patent/US10493075B2/en active Active
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2019
- 2019-07-02 JP JP2019123306A patent/JP6879582B2/ja active Active
- 2019-10-21 US US16/659,401 patent/US10925877B2/en active Active
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2020
- 2020-06-12 AU AU2020203880A patent/AU2020203880B2/en active Active
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2021
- 2021-01-20 US US17/153,749 patent/US11717522B2/en active Active
- 2021-04-22 JP JP2021072278A patent/JP7178731B2/ja active Active
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2023
- 2023-07-20 US US18/224,515 patent/US20230355630A1/en active Pending
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