CY1115862T1 - Θεραπεια με πιρφενιδονη για ασθενεις με μη φυσιολογικη ηπατικη λειτουργια - Google Patents

Θεραπεια με πιρφενιδονη για ασθενεις με μη φυσιολογικη ηπατικη λειτουργια

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Publication number
CY1115862T1
CY1115862T1 CY20141101019T CY141101019T CY1115862T1 CY 1115862 T1 CY1115862 T1 CY 1115862T1 CY 20141101019 T CY20141101019 T CY 20141101019T CY 141101019 T CY141101019 T CY 141101019T CY 1115862 T1 CY1115862 T1 CY 1115862T1
Authority
CY
Cyprus
Prior art keywords
pirfenidone
administration
patient
pirphenidone
adoption
Prior art date
Application number
CY20141101019T
Other languages
English (en)
Inventor
Williamson Ziegler Bradford
Javier Szwarcberg
Original Assignee
Intermune, Inc.
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=41427890&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CY1115862(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from US12/428,393 external-priority patent/US7566729B1/en
Application filed by Intermune, Inc. filed Critical Intermune, Inc.
Publication of CY1115862T1 publication Critical patent/CY1115862T1/el

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    • A61K31/435Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4412Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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    • A61K31/44Non condensed pyridines; Hydrogenated derivatives thereof
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Abstract

Προσφέρονται μέθοδοι για τη χορήγηση πιρφενιδόνης σε έναν ασθενή ο οποίος επιδεικνύει μη φυσιολογικούς βιοδείκτες της λειτουργίας του ήπατος ως απάντηση στη χορήγηση πιρφενιδόνης. Οι μέθοδοι περιλαμβάνουν τη χορήγηση σε έναν ασθενή πιρφενιδόνης σε χαμηλότερες δόσεις από ότι η πλήρης δοσολογία στόχος για μια χρονική περίοδο, που ακολουθείται από χορήγηση στον ασθενή πιρφενιδόνης στην πλήρη δοσολογία στόχο. Οι μέθοδοι περιλαμβάνουν επίσης τη χορήγηση πιρφενιδόνης στην πλήρη δοσολογία στόχο χωρίς μείωση και τη χορήγηση μόνιμα μειωμένων δόσεων πιρφενιδόνης.
CY20141101019T 2008-11-10 2014-12-08 Θεραπεια με πιρφενιδονη για ασθενεις με μη φυσιολογικη ηπατικη λειτουργια CY1115862T1 (el)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11310708P 2008-11-10 2008-11-10
US12/428,393 US7566729B1 (en) 2008-11-10 2009-04-22 Modifying pirfenidone treatment for patients with atypical liver function
US22894309P 2009-07-27 2009-07-27
US12/553,292 US7635707B1 (en) 2008-11-10 2009-09-03 Pirfenidone treatment for patients with atypical liver function
EP11001414.9A EP2343070B1 (en) 2008-11-10 2009-11-06 Pirfenidone treatment for patients with atypical liver function

Publications (1)

Publication Number Publication Date
CY1115862T1 true CY1115862T1 (el) 2017-01-25

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