CY1115862T1 - Θεραπεια με πιρφενιδονη για ασθενεις με μη φυσιολογικη ηπατικη λειτουργια - Google Patents
Θεραπεια με πιρφενιδονη για ασθενεις με μη φυσιολογικη ηπατικη λειτουργιαInfo
- Publication number
- CY1115862T1 CY1115862T1 CY20141101019T CY141101019T CY1115862T1 CY 1115862 T1 CY1115862 T1 CY 1115862T1 CY 20141101019 T CY20141101019 T CY 20141101019T CY 141101019 T CY141101019 T CY 141101019T CY 1115862 T1 CY1115862 T1 CY 1115862T1
- Authority
- CY
- Cyprus
- Prior art keywords
- pirfenidone
- administration
- patient
- pirphenidone
- adoption
- Prior art date
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- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4412—Non condensed pyridines; Hydrogenated derivatives thereof having oxo groups directly attached to the heterocyclic ring
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- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4418—Non condensed pyridines; Hydrogenated derivatives thereof having a carbocyclic group directly attached to the heterocyclic ring, e.g. cyproheptadine
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Abstract
Προσφέρονται μέθοδοι για τη χορήγηση πιρφενιδόνης σε έναν ασθενή ο οποίος επιδεικνύει μη φυσιολογικούς βιοδείκτες της λειτουργίας του ήπατος ως απάντηση στη χορήγηση πιρφενιδόνης. Οι μέθοδοι περιλαμβάνουν τη χορήγηση σε έναν ασθενή πιρφενιδόνης σε χαμηλότερες δόσεις από ότι η πλήρης δοσολογία στόχος για μια χρονική περίοδο, που ακολουθείται από χορήγηση στον ασθενή πιρφενιδόνης στην πλήρη δοσολογία στόχο. Οι μέθοδοι περιλαμβάνουν επίσης τη χορήγηση πιρφενιδόνης στην πλήρη δοσολογία στόχο χωρίς μείωση και τη χορήγηση μόνιμα μειωμένων δόσεων πιρφενιδόνης.
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US11310708P | 2008-11-10 | 2008-11-10 | |
US12/428,393 US7566729B1 (en) | 2008-11-10 | 2009-04-22 | Modifying pirfenidone treatment for patients with atypical liver function |
US22894309P | 2009-07-27 | 2009-07-27 | |
US12/553,292 US7635707B1 (en) | 2008-11-10 | 2009-09-03 | Pirfenidone treatment for patients with atypical liver function |
EP11001414.9A EP2343070B1 (en) | 2008-11-10 | 2009-11-06 | Pirfenidone treatment for patients with atypical liver function |
Publications (1)
Publication Number | Publication Date |
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CY1115862T1 true CY1115862T1 (el) | 2017-01-25 |
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Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
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CY20111100614T CY1111595T1 (el) | 2008-11-10 | 2011-06-28 | Τροποποιηση της θεραπειας με πιρφενιδονη για ασθενεις με μη φυσιολογικη ηπατικη λειτουργια |
CY20141101019T CY1115862T1 (el) | 2008-11-10 | 2014-12-08 | Θεραπεια με πιρφενιδονη για ασθενεις με μη φυσιολογικη ηπατικη λειτουργια |
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