CY1107545T1 - Μεθοδοι για την προκληση θανατου καρκινικων κυτταρων και υποχωρησης του ογκου - Google Patents

Μεθοδοι για την προκληση θανατου καρκινικων κυτταρων και υποχωρησης του ογκου

Info

Publication number
CY1107545T1
CY1107545T1 CY20071100296T CY071100296T CY1107545T1 CY 1107545 T1 CY1107545 T1 CY 1107545T1 CY 20071100296 T CY20071100296 T CY 20071100296T CY 071100296 T CY071100296 T CY 071100296T CY 1107545 T1 CY1107545 T1 CY 1107545T1
Authority
CY
Cyprus
Prior art keywords
methods
cancer cells
tumor cell
causing death
cancer
Prior art date
Application number
CY20071100296T
Other languages
English (en)
Inventor
Walter R Bishop
Diana L Brassard
Tattanahalli L Nagabhushan
Original Assignee
Schering Corporation
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corporation filed Critical Schering Corporation
Publication of CY1107545T1 publication Critical patent/CY1107545T1/el

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/445—Non condensed piperidines, e.g. piperocaine
    • A61K31/4523—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems
    • A61K31/4545—Non condensed piperidines, e.g. piperocaine containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring hetero atom, e.g. pipamperone, anabasine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A61P35/02—Antineoplastic agents specific for leukemia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

Παρέχονται μέθοδοι για τη θεραπεία του καρκίνου, οι οποίες περιλαμβάνουν τη χορήγηση (1) ενός αναστολέα τρανφεράσης φαρνεσυλπρωτεΐνης εν συνδυασμώ με (2) ένα επιπλέον αναστολέα οδού σηματοδότησης Ras για να προκληθεί ο θάνατος των καρκινικών κυττάρων και η υποχώρηση του όγκου.
CY20071100296T 1999-04-09 2007-03-01 Μεθοδοι για την προκληση θανατου καρκινικων κυτταρων και υποχωρησης του ογκου CY1107545T1 (el)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US09/289,255 US6316462B1 (en) 1999-04-09 1999-04-09 Methods of inducing cancer cell death and tumor regression
EP00921765A EP1165078B1 (en) 1999-04-09 2000-04-06 Methods of inducing cancer cell death and tumor regression

Publications (1)

Publication Number Publication Date
CY1107545T1 true CY1107545T1 (el) 2013-03-13

Family

ID=23110723

Family Applications (1)

Application Number Title Priority Date Filing Date
CY20071100296T CY1107545T1 (el) 1999-04-09 2007-03-01 Μεθοδοι για την προκληση θανατου καρκινικων κυτταρων και υποχωρησης του ογκου

Country Status (24)

Country Link
US (1) US6316462B1 (el)
EP (1) EP1165078B1 (el)
JP (1) JP2003529540A (el)
CN (1) CN100421661C (el)
AR (1) AR023400A1 (el)
AT (1) ATE347360T1 (el)
AU (1) AU783177B2 (el)
BR (1) BR0009670A (el)
CA (1) CA2364675A1 (el)
CY (1) CY1107545T1 (el)
DE (1) DE60032226T2 (el)
DK (1) DK1165078T3 (el)
ES (1) ES2275505T3 (el)
HK (1) HK1038512B (el)
HU (1) HUP0200773A3 (el)
MX (1) MXPA01010211A (el)
MY (1) MY120841A (el)
NO (1) NO329133B1 (el)
NZ (1) NZ514628A (el)
PE (1) PE20010025A1 (el)
PT (1) PT1165078E (el)
TW (1) TWI255184B (el)
WO (1) WO2000061145A1 (el)
ZA (1) ZA200108258B (el)

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EP1165078B1 (en) 2006-12-06
AU4204100A (en) 2000-11-14
MY120841A (en) 2005-11-30
BR0009670A (pt) 2002-01-15
WO2000061145A1 (en) 2000-10-19
JP2003529540A (ja) 2003-10-07
CN100421661C (zh) 2008-10-01
DK1165078T3 (da) 2007-04-16
DE60032226T2 (de) 2007-10-11
TWI255184B (en) 2006-05-21
NO329133B1 (no) 2010-08-30
EP1165078A1 (en) 2002-01-02
CA2364675A1 (en) 2000-10-19
NO20014897D0 (no) 2001-10-08
US6316462B1 (en) 2001-11-13
NZ514628A (en) 2004-01-30
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PT1165078E (pt) 2007-02-28
ES2275505T3 (es) 2007-06-16
ATE347360T1 (de) 2006-12-15
HUP0200773A2 (hu) 2002-07-29
CN1364084A (zh) 2002-08-14
NO20014897L (no) 2001-12-10
AU783177B2 (en) 2005-09-29
DE60032226D1 (de) 2007-01-18
AR023400A1 (es) 2002-09-04
HK1038512A1 (en) 2002-03-22
HUP0200773A3 (en) 2003-04-28
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