CO7200259A2 - Nuevos derivados de piridina - Google Patents

Nuevos derivados de piridina

Info

Publication number
CO7200259A2
CO7200259A2 CO15025964A CO15025964A CO7200259A2 CO 7200259 A2 CO7200259 A2 CO 7200259A2 CO 15025964 A CO15025964 A CO 15025964A CO 15025964 A CO15025964 A CO 15025964A CO 7200259 A2 CO7200259 A2 CO 7200259A2
Authority
CO
Colombia
Prior art keywords
pyridine derivatives
new pyridine
new
compound
formula
Prior art date
Application number
CO15025964A
Other languages
English (en)
Inventor
Lilli Anselm
David Banner
Wolfgang Haap
Bernd Kuhn
Thomas Luebbers
Jens-Uwe Peters
Beat Spinnler
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=46851300&utm_source=***_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=CO7200259(A2) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of CO7200259A2 publication Critical patent/CO7200259A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/08—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing alicyclic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
    • A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/4841—Filling excipients; Inactive ingredients
    • A61K9/4858—Organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/12—Drugs for disorders of the urinary system of the kidneys
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/14—Vasoprotectives; Antihaemorrhoidals; Drugs for varicose therapy; Capillary stabilisers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings

Abstract

La invención se refiere a un compuesto de fórmula (I) en el que A, Ay Ra Rse definen tal como en la descripción y en las reivindicaciones. El compuesto de fórmula (I) pueden usarse como un medicamento. 1 2 1 6
CO15025964A 2012-08-21 2015-02-09 Nuevos derivados de piridina CO7200259A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP12181247 2012-08-21

Publications (1)

Publication Number Publication Date
CO7200259A2 true CO7200259A2 (es) 2015-02-27

Family

ID=46851300

Family Applications (1)

Application Number Title Priority Date Filing Date
CO15025964A CO7200259A2 (es) 2012-08-21 2015-02-09 Nuevos derivados de piridina

Country Status (24)

Country Link
US (1) US9409882B2 (es)
EP (1) EP2888244A1 (es)
JP (1) JP2015530997A (es)
KR (1) KR20150044947A (es)
CN (1) CN104583198A (es)
AR (1) AR092172A1 (es)
AU (1) AU2013305102A1 (es)
BR (1) BR112015003217A2 (es)
CA (1) CA2879796A1 (es)
CL (1) CL2015000354A1 (es)
CO (1) CO7200259A2 (es)
CR (1) CR20150073A (es)
EA (1) EA025166B1 (es)
HK (1) HK1206716A1 (es)
IL (1) IL237128A0 (es)
IN (1) IN2015DN00962A (es)
MA (1) MA37893A1 (es)
MX (1) MX2015002026A (es)
PE (1) PE20150995A1 (es)
PH (1) PH12015500262A1 (es)
SG (1) SG11201500900YA (es)
TW (1) TW201412728A (es)
WO (1) WO2014029722A1 (es)
ZA (1) ZA201500625B (es)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR20180111862A (ko) * 2016-02-26 2018-10-11 에프. 호프만-라 로슈 아게 신규 피롤리딘 유도체
MX2019008756A (es) 2017-01-24 2019-09-11 Astellas Pharma Inc Compuesto de prolinamida sustituida por fenildiflurometilo.

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9903610D0 (sv) 1999-10-06 1999-10-06 Astra Ab Novel compounds II
AU2006204159A1 (en) 2005-01-06 2006-07-13 Astrazeneca Ab Novel pyridine compounds
EP1979345B1 (en) 2006-01-24 2009-11-04 Actelion Pharmaceuticals Ltd. Novel pyridine derivatives
US8969386B2 (en) * 2007-05-09 2015-03-03 Vertex Pharmaceuticals Incorporated Modulators of CFTR
CA2706576A1 (en) 2007-11-30 2009-06-04 F. Hoffmann-La Roche Ag Pyridine compounds
ES2389042T3 (es) 2008-03-06 2012-10-22 Actelion Pharmaceuticals Ltd. Compuestos de piridina
SI2421826T1 (sl) 2009-04-20 2014-02-28 F. Hoffmann-La Roche Ag Derivati prolina kot inhibitorji katepsina
US8394834B2 (en) * 2009-08-25 2013-03-12 Hoffman-La Roche Inc. Pyrrolidines as NK3 receptor antagonists
CA2850551A1 (en) 2011-09-30 2013-04-04 Endo Pharmaceuticals Inc. Pyridine derivatives

Also Published As

Publication number Publication date
ZA201500625B (en) 2016-08-31
PH12015500262A1 (en) 2015-03-30
IN2015DN00962A (es) 2015-06-12
AU2013305102A1 (en) 2015-02-12
MX2015002026A (es) 2015-06-05
WO2014029722A1 (en) 2014-02-27
PE20150995A1 (es) 2015-06-29
HK1206716A1 (en) 2016-01-15
EA201590363A1 (ru) 2015-06-30
KR20150044947A (ko) 2015-04-27
EA025166B1 (ru) 2016-11-30
CA2879796A1 (en) 2014-02-27
CN104583198A (zh) 2015-04-29
EP2888244A1 (en) 2015-07-01
JP2015530997A (ja) 2015-10-29
US9409882B2 (en) 2016-08-09
MA37893A1 (fr) 2017-08-31
AR092172A1 (es) 2015-03-25
BR112015003217A2 (pt) 2017-07-04
SG11201500900YA (en) 2015-03-30
CL2015000354A1 (es) 2015-10-23
CR20150073A (es) 2015-03-13
TW201412728A (zh) 2014-04-01
US20150307472A1 (en) 2015-10-29
IL237128A0 (en) 2015-03-31

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