CO6731129A2 - Proceso para la preparación de 4-amino-5-flúor-3-halo-6-(susbtituido)picolinatos - Google Patents

Proceso para la preparación de 4-amino-5-flúor-3-halo-6-(susbtituido)picolinatos

Info

Publication number
CO6731129A2
CO6731129A2 CO13175761A CO13175761A CO6731129A2 CO 6731129 A2 CO6731129 A2 CO 6731129A2 CO 13175761 A CO13175761 A CO 13175761A CO 13175761 A CO13175761 A CO 13175761A CO 6731129 A2 CO6731129 A2 CO 6731129A2
Authority
CO
Colombia
Prior art keywords
fluorine
picolinates
halo
amino
substituted
Prior art date
Application number
CO13175761A
Other languages
English (en)
Inventor
Yuanming Zhu
Gregory T Whiteker
James M Renga
Kim E Arndt
Gary Alan Roth
David E Podhorez
Scott P West
Original Assignee
Dow Agrosciences Llc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Agrosciences Llc filed Critical Dow Agrosciences Llc
Publication of CO6731129A2 publication Critical patent/CO6731129A2/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/81—Amides; Imides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/803—Processes of preparation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pyridine Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Abstract

Los 4-amino-5-flúor-3-halo-6- (substituido) picolinatos son convenientemente preparados desde 4,5,6-tricloropicolinonitrilo mediante una serie de pasos que involucran al intercambio de flúor, la aminación, el intercambio de halógeno, la halogenación, la hidrólisis de nitrilo, la esterificación, y el acoplamiento de un metal de transición asistido.
CO13175761A 2011-01-25 2013-07-25 Proceso para la preparación de 4-amino-5-flúor-3-halo-6-(susbtituido)picolinatos CO6731129A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US201161435936P 2011-01-25 2011-01-25

Publications (1)

Publication Number Publication Date
CO6731129A2 true CO6731129A2 (es) 2013-08-15

Family

ID=46544650

Family Applications (1)

Application Number Title Priority Date Filing Date
CO13175761A CO6731129A2 (es) 2011-01-25 2013-07-25 Proceso para la preparación de 4-amino-5-flúor-3-halo-6-(susbtituido)picolinatos

Country Status (20)

Country Link
US (2) US8754231B2 (es)
EP (1) EP2667712B1 (es)
JP (1) JP5781171B2 (es)
KR (2) KR101537880B1 (es)
CN (1) CN103458689B (es)
AR (1) AR085020A1 (es)
AU (1) AU2012209281B2 (es)
BR (2) BR112013018945A2 (es)
CA (1) CA2825468C (es)
CO (1) CO6731129A2 (es)
HK (1) HK1188684A1 (es)
IL (1) IL227647B (es)
MX (1) MX338962B (es)
PL (1) PL2667712T3 (es)
RU (1) RU2542985C1 (es)
SG (1) SG192101A1 (es)
TW (1) TWI537252B (es)
UA (1) UA109806C2 (es)
WO (1) WO2012103045A1 (es)
ZA (1) ZA201305582B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN103763923B (zh) * 2011-06-30 2016-08-17 陶氏益农公司 3-烷氧基-4-氨基-6-(取代的)吡啶甲酸酯、3-硫代烷基-4-氨基-6-(取代的)吡啶甲酸酯和3-氨基-4-氨基-6-(取代的)吡啶甲酸酯以及它们作为除草剂的用途
AR092355A1 (es) 2012-07-24 2015-04-15 Dow Agrosciences Llc Fluoruros de fluoropicolinoilo y procesos para su preparacion
AR091856A1 (es) 2012-07-24 2015-03-04 Dow Agrosciences Llc Proceso para la preparacion de 4-amino-5-fluor-3-halo-6-(substituido) picolinatos
JP6239003B2 (ja) * 2012-12-13 2017-11-29 ダウ アグロサイエンシィズ エルエルシー ４−アミノ−５−フルオロ−３−クロロ−６−（置換）ピコリネートの調製方法
TW201609652A (zh) 2013-11-12 2016-03-16 陶氏農業科學公司 用於氟化化合物之過程（三）
TW201609651A (zh) 2013-11-12 2016-03-16 陶氏農業科學公司 用於氟化化合物之過程（一）
BR102014028164A2 (pt) * 2013-11-12 2015-09-08 Dow Agrosciences Llc processo para fluoração de compostos
TWI726900B (zh) 2015-08-04 2021-05-11 美商陶氏農業科學公司 用於氟化化合物之過程
KR102384531B1 (ko) * 2016-07-07 2022-04-08 코르테바 애그리사이언스 엘엘씨 4-알콕시-3-(아실 또는 알킬)옥시피콜린아미드의 제조 방법
KR102627532B1 (ko) * 2018-02-02 2024-01-19 칸토 덴카 코교 가부시키가이샤 수소 및 불소 및/또는 염소를 함유한 부타디엔 골격을 갖는 화합물의 제조 방법
EP3853205A1 (en) 2018-09-19 2021-07-28 Corteva Agriscience LLC Preparation of halogen analogs of picloram
EP4121414A1 (en) 2020-03-18 2023-01-25 Corteva Agriscience LLC Improved synthesis of 4-amino-6-(heterocyclic)picolinates
US20230174490A1 (en) 2020-03-18 2023-06-08 Corteva Agriscience Llc Improved synthesis of 6-aryl-4-aminopicolinates

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3285925A (en) * 1962-03-06 1966-11-15 Dow Chemical Co Amino-trichloropicolinic acid compounds
US3325272A (en) 1965-06-23 1967-06-13 Dow Chemical Co Plant growth control methods and compositions
US3629424A (en) 1967-12-26 1971-12-21 Dow Chemical Co Cyanofluoropyridines and fungicidal compositions and methods for using the same
US3803159A (en) * 1967-12-26 1974-04-09 Dow Chemical Co Fluorine containing cyanopyridines
CN1042333C (zh) * 1992-10-14 1999-03-03 美国氰胺公司 5,6－二取代－3－吡啶甲基卤化铵类化合物及其制备方法
FR2803592A1 (fr) * 2000-01-06 2001-07-13 Aventis Cropscience Sa Nouveaux derives de l'acide 3-hydroxypicolinique, leur procede de preparation et compositions fongicides les contenant.
MXPA02006933A (es) * 2000-01-14 2003-01-28 Dow Agrosciences Llc 4-aminopicolinatos y su uso como herbicidas.
US6297197B1 (en) 2000-01-14 2001-10-02 Dow Agrosciences Llc 4-aminopicolinates and their use as herbicides
AR037228A1 (es) * 2001-07-30 2004-11-03 Dow Agrosciences Llc Compuestos del acido 6-(aril o heteroaril)-4-aminopicolinico, composicion herbicida que los comprende y metodo para controlar vegetacion no deseada
UA82358C2 (uk) * 2003-04-02 2008-04-10 Дау Агросайенсиз Ллс 6-алкіл або алкеніл-4-амінопіколінати гербіцидна композиція, спосіб боротьби з небажаною рослинністю
WO2006062979A1 (en) * 2004-12-06 2006-06-15 E.I. Dupont De Nemours And Company Herbicidal 6-cyclopropyl-substitute 4-aminopicolinic acid derivatives
CN102731381B (zh) 2006-01-13 2016-08-17 美国陶氏益农公司 6-（多取代芳基）-4-氨基吡啶甲酸酯及其作为除草剂的用途
ES2391081T3 (es) * 2007-10-02 2012-11-21 Dow Agrosciences, Llc Ácidos 4-amino-picolínicos sustituidos y su uso como herbicidas
US8252938B2 (en) * 2009-06-08 2012-08-28 Dow Agrosciences, Llc. Process for the preparation of 6-(aryl)-4-aminopicolinates
GB0910766D0 (en) * 2009-06-22 2009-08-05 Syngenta Ltd Chemical compounds

Also Published As

Publication number Publication date
EP2667712A4 (en) 2014-06-04
US8993772B2 (en) 2015-03-31
RU2542985C1 (ru) 2015-02-27
PL2667712T3 (pl) 2017-06-30
SG192101A1 (en) 2013-08-30
BR102012001643A2 (pt) 2014-04-22
HK1188684A1 (zh) 2014-05-16
KR20150013334A (ko) 2015-02-04
MX2013008602A (es) 2013-12-09
ZA201305582B (en) 2014-09-25
IL227647B (en) 2018-10-31
US20120190859A1 (en) 2012-07-26
CA2825468A1 (en) 2012-08-02
RU2013139379A (ru) 2015-03-10
IL227647A0 (en) 2013-09-30
EP2667712B1 (en) 2016-08-31
JP5781171B2 (ja) 2015-09-16
JP2014505073A (ja) 2014-02-27
TWI537252B (zh) 2016-06-11
EP2667712A1 (en) 2013-12-04
TW201309648A (zh) 2013-03-01
KR101537880B1 (ko) 2015-07-17
AR085020A1 (es) 2013-08-07
AU2012209281B2 (en) 2015-06-25
US8754231B2 (en) 2014-06-17
CA2825468C (en) 2016-08-23
CN103458689B (zh) 2015-09-23
UA109806C2 (uk) 2015-10-12
WO2012103045A1 (en) 2012-08-02
CN103458689A (zh) 2013-12-18
BR112013018945A2 (pt) 2017-05-02
KR20130121952A (ko) 2013-11-06
US20140206881A1 (en) 2014-07-24
MX338962B (es) 2016-05-06

Similar Documents

Publication Publication Date Title
CO6731129A2 (es) Proceso para la preparación de 4-amino-5-flúor-3-halo-6-(susbtituido)picolinatos
CO6731130A2 (es) Proceso para la preparación de 4-amino-5-fluoro-3-halo-6-picolinatos(sustituidos)
CO6731125A2 (es) Proceso para la preparación de 4-amino-3-cloro-5-fluoro-6-picolinatos (sustituidos)
CO6731128A2 (es) Proceso para la preparación de 4-amino-3-cloro-5-fluoro-6-picolinatos (sustituidos)
CO6400216A2 (es) Metodo de preparación de un inhibidor de citocromo p450 monooxigenasa, y productos intermedios involucrados
CL2016002262A1 (es) Composiciones y métodos para modular la expresión de ttr y vhb
CL2015000739A1 (es) Compuesto para juntas, ensamble de muro, y métodos y productos relacionados a estos.
BR112013029498A2 (pt) “método para produzir um suíno geneticamente modificado.”
CO2017000049A2 (es) Reactivos y compuestos intermediarios para el proceso para la preparación de ácidos 4-alcoxi hidroxipicolínicos
BR112014017722A8 (pt) Método para definição de parâmetros de conexão de rede e aparelho do mesmo
BR112014026149A2 (pt) método para a preparação de 2,4-ácido dihidroxibutírico (2,4-dhb) e microrganismo.
CL2012002082A1 (es) Proceso para la preparacion de lacosamida, por hidroximetilación; compuestos intermediarios.
JP2011184436A5 (es)
AR085052A1 (es) Metodos para producir un compuesto profarmaco inhibidor de la union al vih e intermediarios
BR112015024859A2 (pt) processo e intermediários para a preparação de pregabalina
BR112013029034A2 (pt) processo de fabricação de uma peça monobloco para uma turbomáquina através de soldagem por difusão
BR112014030033A2 (pt) processo para preparação de dialopiridinas
GT201300078A (es) Proceso para la preparacion de inhibidores de pan-cdk de la formula ( i ), e intermediarios de la preparacion
BR112018014763A2 (pt) processo para a preparação de ácidos 4-alcóxi-3-hidroxipicolínicos
BR112013031445A2 (pt) espessantes associativos à base de (met) acrilato
CL2013003070A1 (es) Sales (2e)-3-carboxiacrilato, fosfatodihidrogeno y 2,6-dioxido-1.2,3,6-tetrahidropirimidina-4-carboxilato de 3-carboxi-n-etil-n,n-dimetilpropan-1-amonio; procedimiento de preparacion; y uso en el tratamiento de enfermedades cardiovasculares.
TH150488A (th) กรรมวิธีสำหรับการเตรียม 4-อะมิโน-3-คลอโร-5-ฟลูออโร-6-(ซับสติติวเตด)พิโคลิเนต
CR20110423A (es) Macrolindo anti-inflamatorio
TH141686A (th) กรรมวิธีสำหรับการเตรียม 4-อะมิโน-5-ฟลูออโร-3-ฮาโล-6-(ซับสติติวเตด)พิโคลิเนต
AR090789A1 (es) Intermediarios y procesos para la preparacion de compuestos