CO6321280A2 - Nueva clase espiro piperidinas para el tratamiento de enfermedades neurodegenerativas - Google Patents
Nueva clase espiro piperidinas para el tratamiento de enfermedades neurodegenerativasInfo
- Publication number
- CO6321280A2 CO6321280A2 CO10141834A CO10141834A CO6321280A2 CO 6321280 A2 CO6321280 A2 CO 6321280A2 CO 10141834 A CO10141834 A CO 10141834A CO 10141834 A CO10141834 A CO 10141834A CO 6321280 A2 CO6321280 A2 CO 6321280A2
- Authority
- CO
- Colombia
- Prior art keywords
- treatment
- piperidinas
- espiro
- class
- new
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
Se desvelan compuestos y sales farmacéuticamente aceptables de los compuestos, teniendo los compuestos la estructura de Fórmula Icomo se define en la memoria descriptiva. También se desvelan composiciones farmacéuticas, procedimientos de tratamiento, procedimientos de síntesis e intermedios correspondientes.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US5042308P | 2008-05-05 | 2008-05-05 |
Publications (1)
Publication Number | Publication Date |
---|---|
CO6321280A2 true CO6321280A2 (es) | 2011-09-20 |
Family
ID=40902870
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO10141834A CO6321280A2 (es) | 2008-05-05 | 2010-11-11 | Nueva clase espiro piperidinas para el tratamiento de enfermedades neurodegenerativas |
Country Status (22)
Country | Link |
---|---|
US (1) | US20110046160A1 (es) |
EP (1) | EP2300484B1 (es) |
JP (1) | JP2011519913A (es) |
KR (1) | KR20110000749A (es) |
CN (1) | CN102083841A (es) |
AP (1) | AP2010005456A0 (es) |
AT (1) | ATE537178T1 (es) |
AU (1) | AU2009245322B2 (es) |
BR (1) | BRPI0912433A2 (es) |
CA (1) | CA2721786A1 (es) |
CO (1) | CO6321280A2 (es) |
CR (1) | CR11759A (es) |
DO (1) | DOP2010000317A (es) |
EA (1) | EA201001566A1 (es) |
EC (1) | ECSP10010597A (es) |
ES (1) | ES2375913T3 (es) |
IL (1) | IL208793A0 (es) |
MA (1) | MA32290B1 (es) |
MX (1) | MX2010012066A (es) |
NZ (1) | NZ588589A (es) |
SV (1) | SV2010003725A (es) |
WO (1) | WO2009136350A1 (es) |
Families Citing this family (8)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7763609B2 (en) | 2003-12-15 | 2010-07-27 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
UA108363C2 (uk) | 2009-10-08 | 2015-04-27 | Похідні імінотіадіазиндіоксиду як інгібітори bace, композиція на їх основі і їх застосування | |
CA2795877A1 (en) * | 2010-04-09 | 2011-10-13 | Pfizer Inc. | Novel sultam compounds |
EP2694521B1 (en) | 2011-04-07 | 2015-11-25 | Merck Sharp & Dohme Corp. | Pyrrolidine-fused thiadiazine dioxide compounds as bace inhibitors, compositions, and their use |
EP2694489B1 (en) | 2011-04-07 | 2017-09-06 | Merck Sharp & Dohme Corp. | C5-c6 oxacyclic-fused thiadiazine dioxide compounds as bace inhibitors, compositions, and their use |
WO2013028670A1 (en) | 2011-08-22 | 2013-02-28 | Merck Sharp & Dohme Corp. | 2-spiro-substituted iminothiazines and their mono-and dioxides as bace inhibitors, compositions and their use |
EP3233799B1 (en) | 2014-12-19 | 2021-05-19 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
WO2016100940A1 (en) | 2014-12-19 | 2016-06-23 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE602004031560D1 (de) * | 2004-01-08 | 2011-04-07 | Hoffmann La Roche | Diazaspiropiperidinderivate |
JP2006044497A (ja) * | 2004-08-05 | 2006-02-16 | Toyota Motor Corp | 車輪情報処理装置 |
AU2005295814A1 (en) * | 2004-10-13 | 2006-04-27 | Merck & Co., Inc. | Spiropiperidine compounds useful as beta-secretase inhibitors for the treatment of Alzhermer's disease |
ATE550338T1 (de) * | 2005-07-18 | 2012-04-15 | Merck Sharp & Dohme | Spiropiperidininhibitoren von beta-secretase zur behandlung von alzheimer-krankheit |
JP2010502705A (ja) * | 2006-09-07 | 2010-01-28 | メルク エンド カムパニー インコーポレーテッド | アルツハイマー病の治療用としてのスピロピペリジンベータセクレターゼ阻害剤 |
CA2673888A1 (en) * | 2007-01-04 | 2008-07-17 | Merck And Co., Inc. | Bicyclic spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease |
-
2009
- 2009-05-04 US US12/990,739 patent/US20110046160A1/en not_active Abandoned
- 2009-05-04 NZ NZ588589A patent/NZ588589A/en not_active IP Right Cessation
- 2009-05-04 AT AT09742523T patent/ATE537178T1/de active
- 2009-05-04 KR KR1020107024794A patent/KR20110000749A/ko not_active Application Discontinuation
- 2009-05-04 EP EP09742523A patent/EP2300484B1/en active Active
- 2009-05-04 AP AP2010005456A patent/AP2010005456A0/xx unknown
- 2009-05-04 CA CA2721786A patent/CA2721786A1/en not_active Abandoned
- 2009-05-04 ES ES09742523T patent/ES2375913T3/es active Active
- 2009-05-04 CN CN2009801261947A patent/CN102083841A/zh active Pending
- 2009-05-04 EA EA201001566A patent/EA201001566A1/ru unknown
- 2009-05-04 WO PCT/IB2009/051815 patent/WO2009136350A1/en active Application Filing
- 2009-05-04 BR BRPI0912433A patent/BRPI0912433A2/pt not_active Application Discontinuation
- 2009-05-04 JP JP2011508035A patent/JP2011519913A/ja not_active Withdrawn
- 2009-05-04 AU AU2009245322A patent/AU2009245322B2/en not_active Ceased
- 2009-05-04 MX MX2010012066A patent/MX2010012066A/es not_active Application Discontinuation
-
2010
- 2010-10-18 IL IL208793A patent/IL208793A0/en unknown
- 2010-10-21 DO DO2010000317A patent/DOP2010000317A/es unknown
- 2010-10-26 CR CR11759A patent/CR11759A/es not_active Application Discontinuation
- 2010-11-05 MA MA33328A patent/MA32290B1/fr unknown
- 2010-11-05 SV SV2010003725A patent/SV2010003725A/es not_active Application Discontinuation
- 2010-11-09 EC EC2010010597A patent/ECSP10010597A/es unknown
- 2010-11-11 CO CO10141834A patent/CO6321280A2/es not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP2011519913A (ja) | 2011-07-14 |
US20110046160A1 (en) | 2011-02-24 |
DOP2010000317A (es) | 2010-11-15 |
ATE537178T1 (de) | 2011-12-15 |
KR20110000749A (ko) | 2011-01-05 |
AU2009245322A1 (en) | 2009-11-12 |
WO2009136350A1 (en) | 2009-11-12 |
CA2721786A1 (en) | 2009-11-12 |
EP2300484A1 (en) | 2011-03-30 |
AP2010005456A0 (en) | 2010-12-31 |
CR11759A (es) | 2010-11-22 |
EA201001566A1 (ru) | 2011-04-29 |
AU2009245322B2 (en) | 2011-07-14 |
BRPI0912433A2 (pt) | 2015-12-22 |
SV2010003725A (es) | 2011-07-05 |
IL208793A0 (en) | 2010-12-30 |
NZ588589A (en) | 2012-07-27 |
ECSP10010597A (es) | 2010-12-30 |
ES2375913T3 (es) | 2012-03-07 |
CN102083841A (zh) | 2011-06-01 |
MX2010012066A (es) | 2010-12-06 |
EP2300484B1 (en) | 2011-12-14 |
MA32290B1 (fr) | 2011-05-02 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FA | Application withdrawn |