SV2010003725A - Nueva clase de espiro piperidinas para el tratamiento de enfermedades neurodegenerativas - Google Patents
Nueva clase de espiro piperidinas para el tratamiento de enfermedades neurodegenerativasInfo
- Publication number
- SV2010003725A SV2010003725A SV2010003725A SV2010003725A SV2010003725A SV 2010003725 A SV2010003725 A SV 2010003725A SV 2010003725 A SV2010003725 A SV 2010003725A SV 2010003725 A SV2010003725 A SV 2010003725A SV 2010003725 A SV2010003725 A SV 2010003725A
- Authority
- SV
- El Salvador
- Prior art keywords
- treatment
- espiro
- piperidines
- neurodegenerative diseases
- new class
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/10—Spiro-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Abstract
SE DESVELAN COMPUESTOS Y SALES FARMACÉUTICAMENTE ACEPTABLES DE LOS COMPUESTOS, TENIENDO LOS COMPUESTOS LA ESTRUCTURA DE FORMULA I: (VER FORMULA); COMO SE DEFINE EN LA MEMORIA DESCRIPTIVA. TAMBIÉN SE DESVELAN COMPOSICIONES FARMACÉUTICAS, PROCEDIMIENTOS DE TRATAMIENTO, PROCEDIMIENTOS DE SÍNTESIS E INTERMEDIOS CORRESPONDIENTES
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US5042308P | 2008-05-05 | 2008-05-05 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SV2010003725A true SV2010003725A (es) | 2011-07-05 |
Family
ID=40902870
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SV2010003725A SV2010003725A (es) | 2008-05-05 | 2010-11-05 | Nueva clase de espiro piperidinas para el tratamiento de enfermedades neurodegenerativas |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US20110046160A1 (es) |
| EP (1) | EP2300484B1 (es) |
| JP (1) | JP2011519913A (es) |
| KR (1) | KR20110000749A (es) |
| CN (1) | CN102083841A (es) |
| AP (1) | AP2010005456A0 (es) |
| AT (1) | ATE537178T1 (es) |
| AU (1) | AU2009245322B2 (es) |
| BR (1) | BRPI0912433A2 (es) |
| CA (1) | CA2721786A1 (es) |
| CO (1) | CO6321280A2 (es) |
| CR (1) | CR11759A (es) |
| DO (1) | DOP2010000317A (es) |
| EA (1) | EA201001566A1 (es) |
| EC (1) | ECSP10010597A (es) |
| ES (1) | ES2375913T3 (es) |
| IL (1) | IL208793A0 (es) |
| MA (1) | MA32290B1 (es) |
| MX (1) | MX2010012066A (es) |
| NZ (1) | NZ588589A (es) |
| SV (1) | SV2010003725A (es) |
| WO (1) | WO2009136350A1 (es) |
Families Citing this family (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7763609B2 (en) | 2003-12-15 | 2010-07-27 | Schering Corporation | Heterocyclic aspartyl protease inhibitors |
| UA108363C2 (uk) | 2009-10-08 | 2015-04-27 | Похідні імінотіадіазиндіоксиду як інгібітори bace, композиція на їх основі і їх застосування | |
| CA2795877A1 (en) * | 2010-04-09 | 2011-10-13 | Pfizer Inc. | Novel sultam compounds |
| WO2012138590A1 (en) | 2011-04-07 | 2012-10-11 | Merck Sharp & Dohme Corp. | Pyrrolidine-fused thiadiazine dioxide compounds as bace inhibitors, compositions, and their use |
| US9221839B2 (en) | 2011-04-07 | 2015-12-29 | Merck Sharp & Dohme Corp. | C5-C6 oxacyclic-fused thiadiazine dioxide compounds as BACE inhibitors, compositions, and their use |
| MX2014002113A (es) | 2011-08-22 | 2014-04-25 | Merck Sharp & Dohme | Iminotiazinas sustituidas en 2-espiro y sus mono y bioxidos como inhibidores de enzima de disociacion de proteina precursora amiloide del sitio beta, composiciones, y su uso. |
| EP3233799B1 (en) | 2014-12-19 | 2021-05-19 | The Broad Institute, Inc. | Dopamine d2 receptor ligands |
| EP3233077A4 (en) | 2014-12-19 | 2018-08-08 | The Broad Institute Inc. | Dopamine d2 receptor ligands |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN100413865C (zh) * | 2004-01-08 | 2008-08-27 | 弗·哈夫曼-拉罗切有限公司 | 二氮杂-螺哌啶衍生物 |
| JP2006044497A (ja) * | 2004-08-05 | 2006-02-16 | Toyota Motor Corp | 車輪情報処理装置 |
| WO2006044497A2 (en) * | 2004-10-13 | 2006-04-27 | Merck & Co., Inc. | Spiropiperidine compounds useful as beta-secretase inhibitors for the treatment of alzhermer’s disease |
| WO2007011810A1 (en) * | 2005-07-18 | 2007-01-25 | Merck & Co., Inc. | Spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease |
| WO2008030412A2 (en) * | 2006-09-07 | 2008-03-13 | Merck & Co., Inc. | Spiropiperidine beta-secretase inhibitors for the treatment of alzheimer's disease |
| AU2007342368A1 (en) * | 2007-01-04 | 2008-07-17 | Merck & Co., Inc. | Bicyclic spiropiperidine beta-secretase inhibitors for the treatment of Alzheimer's disease |
-
2009
- 2009-05-04 WO PCT/IB2009/051815 patent/WO2009136350A1/en active Application Filing
- 2009-05-04 KR KR1020107024794A patent/KR20110000749A/ko not_active Application Discontinuation
- 2009-05-04 AP AP2010005456A patent/AP2010005456A0/xx unknown
- 2009-05-04 CA CA2721786A patent/CA2721786A1/en not_active Abandoned
- 2009-05-04 BR BRPI0912433A patent/BRPI0912433A2/pt not_active Application Discontinuation
- 2009-05-04 JP JP2011508035A patent/JP2011519913A/ja not_active Withdrawn
- 2009-05-04 US US12/990,739 patent/US20110046160A1/en not_active Abandoned
- 2009-05-04 CN CN2009801261947A patent/CN102083841A/zh active Pending
- 2009-05-04 NZ NZ588589A patent/NZ588589A/en not_active IP Right Cessation
- 2009-05-04 ES ES09742523T patent/ES2375913T3/es active Active
- 2009-05-04 AT AT09742523T patent/ATE537178T1/de active
- 2009-05-04 EA EA201001566A patent/EA201001566A1/ru unknown
- 2009-05-04 MX MX2010012066A patent/MX2010012066A/es not_active Application Discontinuation
- 2009-05-04 EP EP09742523A patent/EP2300484B1/en active Active
- 2009-05-04 AU AU2009245322A patent/AU2009245322B2/en not_active Ceased
-
2010
- 2010-10-18 IL IL208793A patent/IL208793A0/en unknown
- 2010-10-21 DO DO2010000317A patent/DOP2010000317A/es unknown
- 2010-10-26 CR CR11759A patent/CR11759A/es not_active Application Discontinuation
- 2010-11-05 MA MA33328A patent/MA32290B1/fr unknown
- 2010-11-05 SV SV2010003725A patent/SV2010003725A/es not_active Application Discontinuation
- 2010-11-09 EC EC2010010597A patent/ECSP10010597A/es unknown
- 2010-11-11 CO CO10141834A patent/CO6321280A2/es not_active Application Discontinuation
Also Published As
| Publication number | Publication date |
|---|---|
| ES2375913T3 (es) | 2012-03-07 |
| KR20110000749A (ko) | 2011-01-05 |
| MA32290B1 (fr) | 2011-05-02 |
| AU2009245322A1 (en) | 2009-11-12 |
| BRPI0912433A2 (pt) | 2015-12-22 |
| EA201001566A1 (ru) | 2011-04-29 |
| JP2011519913A (ja) | 2011-07-14 |
| CA2721786A1 (en) | 2009-11-12 |
| ECSP10010597A (es) | 2010-12-30 |
| DOP2010000317A (es) | 2010-11-15 |
| NZ588589A (en) | 2012-07-27 |
| CN102083841A (zh) | 2011-06-01 |
| MX2010012066A (es) | 2010-12-06 |
| IL208793A0 (en) | 2010-12-30 |
| CR11759A (es) | 2010-11-22 |
| EP2300484A1 (en) | 2011-03-30 |
| AU2009245322B2 (en) | 2011-07-14 |
| CO6321280A2 (es) | 2011-09-20 |
| US20110046160A1 (en) | 2011-02-24 |
| EP2300484B1 (en) | 2011-12-14 |
| AP2010005456A0 (en) | 2010-12-31 |
| ATE537178T1 (de) | 2011-12-15 |
| WO2009136350A1 (en) | 2009-11-12 |
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