CO5640126A2 - Derivados de aminoalcohol y composiciones farmaceuticas que las contienen - Google Patents
Derivados de aminoalcohol y composiciones farmaceuticas que las contienenInfo
- Publication number
- CO5640126A2 CO5640126A2 CO04065919A CO04065919A CO5640126A2 CO 5640126 A2 CO5640126 A2 CO 5640126A2 CO 04065919 A CO04065919 A CO 04065919A CO 04065919 A CO04065919 A CO 04065919A CO 5640126 A2 CO5640126 A2 CO 5640126A2
- Authority
- CO
- Colombia
- Prior art keywords
- hydrogen
- pharmaceutical compositions
- compositions containing
- alkylene
- lower alkyl
- Prior art date
Links
- 150000001414 amino alcohols Chemical class 0.000 title abstract 2
- 239000008194 pharmaceutical composition Substances 0.000 title 1
- 239000001257 hydrogen Substances 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 125000006832 (C1-C10) alkylene group Chemical group 0.000 abstract 2
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical group N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 2
- 125000000217 alkyl group Chemical group 0.000 abstract 2
- VGGSQFUCUMXWEO-UHFFFAOYSA-N Ethene Chemical compound C=C VGGSQFUCUMXWEO-UHFFFAOYSA-N 0.000 abstract 1
- 239000005977 Ethylene Substances 0.000 abstract 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical group [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 abstract 1
- 150000002148 esters Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical group 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 230000001506 immunosuppresive effect Effects 0.000 abstract 1
- 229910052757 nitrogen Chemical group 0.000 abstract 1
- 239000001301 oxygen Substances 0.000 abstract 1
- 229910052760 oxygen Inorganic materials 0.000 abstract 1
- 150000003007 phosphonic acid derivatives Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000003107 substituted aryl group Chemical group 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/32—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/33—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms with substituted hydrocarbon radicals, directly attached to ring carbon atoms
- C07D207/335—Radicals substituted by nitrogen atoms not forming part of a nitro radical
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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- A—HUMAN NECESSITIES
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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- A—HUMAN NECESSITIES
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/34—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D307/38—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D307/52—Radicals substituted by nitrogen atoms not forming part of a nitro radical
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/14—Radicals substituted by singly bound hetero atoms other than halogen
- C07D333/20—Radicals substituted by singly bound hetero atoms other than halogen by nitrogen atoms
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having one nitrogen atom as the only ring hetero atom
- C07F9/572—Five-membered rings
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/655—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms
- C07F9/65515—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having oxygen atoms, with or without sulfur, selenium, or tellurium atoms, as the only ring hetero atoms the oxygen atom being part of a five-membered ring
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6553—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms
- C07F9/655345—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having sulfur atoms, with or without selenium or tellurium atoms, as the only ring hetero atoms the sulfur atom being part of a five-membered ring
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Cardiology (AREA)
- Biochemistry (AREA)
- Diabetes (AREA)
- Molecular Biology (AREA)
- Hematology (AREA)
- Immunology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pulmonology (AREA)
- Dermatology (AREA)
- Physical Education & Sports Medicine (AREA)
- Psychiatry (AREA)
- Oncology (AREA)
- Urology & Nephrology (AREA)
- Obesity (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Communicable Diseases (AREA)
- Hospice & Palliative Care (AREA)
- Psychology (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Gastroenterology & Hepatology (AREA)
Abstract
1.- Un derivado de aminoalcohol o derivado de ácido fosfónico cada uno con excelente actividad inmunosupresora; una sal farmacológicamente aceptable del mismo o éster farmacológicamente aceptable del mismo; y una composición medicinal que contiene cualquiera de éstos;(en la fórmula, R1 y R2 cada uno representa hidrógeno o un grupo amino-protector; R3 representa hidrógeno o un grupo hidroxi-protector; R4 representa alquilo inferior; n es un entero de 1 a 6; X representa oxígeno o nitrógeno opcionalmente sustituido por alquilo inferior, etc.; Y representa etileno; Z representa alquileno de C1-C10; R5 representa o arilo sustituido; y R6 y R7 cada uno representa hidrógeno; con la condición de que cuando R5 sea hidrógeno, entonces Z represente un alquileno de C1-C10 no lineal de un enlace sencillo].
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2002004484 | 2002-01-11 | ||
JP2002004456 | 2002-01-11 |
Publications (1)
Publication Number | Publication Date |
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CO5640126A2 true CO5640126A2 (es) | 2006-05-31 |
Family
ID=26625490
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CO04065919A CO5640126A2 (es) | 2002-01-11 | 2004-07-12 | Derivados de aminoalcohol y composiciones farmaceuticas que las contienen |
Country Status (26)
Country | Link |
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US (5) | US7199150B2 (es) |
EP (1) | EP1471054B1 (es) |
JP (1) | JP4270541B2 (es) |
KR (2) | KR100836547B1 (es) |
CN (1) | CN100406437C (es) |
AT (1) | ATE435202T1 (es) |
AU (1) | AU2003202495B2 (es) |
BR (1) | BR0306811A (es) |
CA (1) | CA2473461C (es) |
CO (1) | CO5640126A2 (es) |
CY (1) | CY1109457T1 (es) |
DE (1) | DE60328161D1 (es) |
DK (1) | DK1471054T3 (es) |
ES (1) | ES2327825T3 (es) |
HK (1) | HK1066532A1 (es) |
IL (1) | IL162874A0 (es) |
MX (1) | MXPA04006709A (es) |
NO (1) | NO329134B1 (es) |
NZ (1) | NZ533994A (es) |
PL (1) | PL211954B1 (es) |
PT (1) | PT1471054E (es) |
RU (1) | RU2330839C2 (es) |
SI (1) | SI1471054T1 (es) |
TW (1) | TWI283574B (es) |
WO (1) | WO2003059880A1 (es) |
ZA (1) | ZA200406333B (es) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BR0306811A (pt) * | 2002-01-11 | 2004-10-26 | Sankyo Co | Composto, éster farmacologicamente aceitável do mesmo, composição farmacêutica e métodos para prevenção ou tratamento de doenças autoimunes, da artrite reumatóide e da rejeição causada pelo transplante de vários órgãos em um mamìfero |
JP4771511B2 (ja) * | 2003-07-08 | 2011-09-14 | 第一三共株式会社 | アミノアルコ−ル誘導体又はホスホン酸誘導体を含有する医薬組成物 |
EP1546110A4 (en) | 2002-07-30 | 2008-03-26 | Univ Virginia | ACTIVE COMPOUNDS IN THE SIGNALING OF SPHINGOSINE 1-PHOSPHATE |
GB0302094D0 (en) | 2003-01-29 | 2003-02-26 | Pharmagene Lab Ltd | EP4 receptor antagonists |
WO2005005383A1 (ja) * | 2003-07-11 | 2005-01-20 | Sankyo Company, Limited | アミノアルコール化合物 |
WO2005030848A1 (en) * | 2003-09-19 | 2005-04-07 | Dow Global Technologies Inc. | Multifunctional monomers and polyarylene compositions therefrom |
GB0324269D0 (en) * | 2003-10-16 | 2003-11-19 | Pharmagene Lab Ltd | EP4 receptor antagonists |
WO2005041899A2 (en) | 2003-11-03 | 2005-05-12 | University Of Virginia Patent Foundation | Orally available sphingosine 1-phosphate receptor agonists and antagonists |
ES2232306B1 (es) * | 2003-11-10 | 2006-08-01 | Almirall Prodesfarma, S.A. | Nuevos derivados de piridazin-3(2h)-ona. |
AU2005215320B2 (en) * | 2004-02-24 | 2008-04-17 | Sankyo Company, Limited | Amino alcohol compound |
EP1772145B1 (en) | 2004-07-16 | 2011-03-23 | Kyorin Pharmaceutical Co., Ltd. | Method of effectively using medicine and method concerning prevention of side effect |
JP4919374B2 (ja) * | 2004-07-29 | 2012-04-18 | 第一三共株式会社 | 免疫抑制剤としての医薬組成物 |
TW200611687A (en) * | 2004-07-29 | 2006-04-16 | Sankyo Co | Pharmaceutical compositions used for immunosuppressant |
JP4792400B2 (ja) * | 2004-10-12 | 2011-10-12 | 杏林製薬株式会社 | 2−アミノ−2−[2−[4−(3−ベンジルオキシフェニルチオ)−2−クロロフェニル]エチル]−1,3−プロパンジオール塩酸塩又はその水和物の製造方法及びその製造中間体 |
JP5024851B2 (ja) * | 2004-10-28 | 2012-09-12 | 第一三共株式会社 | 光学活性4,4−二置換オキサゾリジン誘導体とその製造方法 |
US7547790B2 (en) | 2004-10-28 | 2009-06-16 | Sankyo Company, Limited | Optically active 4,4-di-substituted oxazolidine derivative and method for producing same |
JP2008530135A (ja) | 2005-02-14 | 2008-08-07 | ユニバーシティ オブ バージニア パテント ファンデーション | アミノ基およびフェニル基で置換されたシクロアルカンならびに5員の複素環を含むスフィンゴシン=1−リン酸アゴニスト |
TWI418350B (zh) * | 2005-06-24 | 2013-12-11 | Sankyo Co | 含有ppar調節劑之醫藥組成物的用途 |
WO2007043433A1 (ja) * | 2005-10-07 | 2007-04-19 | Kyorin Pharmaceutical Co., Ltd. | 2-アミノ-1,3-プロパンジオール誘導体を有効成分とする肝臓疾患治療剤および肝臓疾患治療方法 |
AU2007209961A1 (en) | 2006-01-27 | 2007-08-09 | University Of Virginia Patent Foundation | Method for treatment of neuropathic pain |
TWI389683B (zh) * | 2006-02-06 | 2013-03-21 | Kyorin Seiyaku Kk | A therapeutic agent for an inflammatory bowel disease or an inflammatory bowel disease treatment using a 2-amino-1,3-propanediol derivative as an active ingredient |
JP2009526073A (ja) | 2006-02-09 | 2009-07-16 | ユニバーシティ オブ バージニア パテント ファンデーション | 二環式スフィンゴシン−1−リン酸受容体アナログ |
TW200815600A (en) | 2006-08-04 | 2008-04-01 | Daiichi Sankyo Co Ltd | An enzyme for phosphorizing a medicine |
TWI396677B (zh) * | 2006-08-08 | 2013-05-21 | Kyorin Seiyaku Kk | An amine alcohol derivative and an immunosuppressive agent for use as an active ingredient |
DK2058317T3 (da) * | 2006-08-08 | 2014-01-06 | Kyorin Seiyaku Kk | Aminophosphorsyreesterderivat og S1P receptormodulator indeholdende samme som aktiv ingrediens |
EP2099741A2 (en) | 2006-11-21 | 2009-09-16 | University Of Virginia Patent Foundation | Hydrindane analogs having sphingosine 1-phosphate receptor agonist activity |
AU2007323557A1 (en) | 2006-11-21 | 2008-05-29 | University Of Virginia Patent Foundation | Benzocycloheptyl analogs having sphingosine 1-phosphate receptor activity |
EP2097397A1 (en) | 2006-11-21 | 2009-09-09 | University Of Virginia Patent Foundation | Tetralin analogs having sphingosine 1-phosphate agonist activity |
TW200906389A (en) | 2007-05-25 | 2009-02-16 | Daiichi Sankyo Co Ltd | Pharmaceutical composition comprising of therapeutic or prophylactic agents for hepatitis |
US8476305B2 (en) | 2008-02-07 | 2013-07-02 | Kyorin Pharmaceutical Co., Ltd. | Therapeutic agent or prophylactic agent for inflammatory bowel disease comprising amino alcohol derivative as active ingredient |
MX339759B (es) * | 2010-07-29 | 2016-06-08 | Fournier Lab Sa | Compuesto para el tratamiento/prevencion de enfermedades inflamatorias oculares. |
FR2963238B1 (fr) * | 2010-07-29 | 2012-12-28 | Fournier Lab Sa | Derives de 15-desoxyspergualine pour le traitement et/ou la prevention des maladies inflammatoires oculaires |
WO2012073991A1 (ja) | 2010-12-02 | 2012-06-07 | 第一三共株式会社 | ピロール誘導体及びその製造方法 |
EP2804605A4 (en) * | 2012-01-20 | 2015-07-08 | Acucela Inc | SUBSTITUTED HETEROCYCLIC COMPOUNDS FOR THE TREATMENT OF DISEASES |
KR20180093177A (ko) | 2017-02-10 | 2018-08-21 | (주)홍익바이오텍 | 죽염과 다공성 광물을 이용한 개껌 제조방법 |
US11034669B2 (en) | 2018-11-30 | 2021-06-15 | Nuvation Bio Inc. | Pyrrole and pyrazole compounds and methods of use thereof |
Family Cites Families (116)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB1134687A (en) | 1966-04-28 | 1968-11-27 | Beecham Group Ltd | Acetylenic compounds |
IL36730A0 (en) | 1970-05-28 | 1971-06-23 | Chemagro Corp | Phosphonamidothioates,their preparation and their use as herbicides and/or plant growth regulators |
DK150068C (da) | 1978-06-02 | 1987-06-29 | Pfizer | Analogifremgangsmaade til fremstilling af aminothiazoler |
FR2460919A1 (fr) | 1979-07-11 | 1981-01-30 | Prod Synthese Ste Indle | Amino-ethers oxydes, leur procede de preparation et leur application en therapeutique |
US4363918A (en) | 1979-09-11 | 1982-12-14 | Janssen Pharmaceutica N.V. | Method of preparing 1-alkyl-3-carboxy-1H pyrrole-2-acetic acids |
SE8107537L (sv) | 1980-12-22 | 1982-06-23 | Delalande Sa | Nya derivat av heterocykliska aminoalcoyler, deras framstellningssett och deras terapeutiska anvendning |
US4716155A (en) | 1981-12-24 | 1987-12-29 | E. R. Squibb & Sons, Inc. | Phosphorus containing compounds and hypotensive use thereof |
IT1190793B (it) | 1982-04-27 | 1988-02-24 | Magis Farmaceutici | Composti attivi nel trattamento dell'ulcera e sintomi allergici della pelle |
US4536601A (en) | 1982-09-28 | 1985-08-20 | Dainippon Pharmaceutical Co., Ltd. | Optically active N-substituted phenylalaninols and use thereof |
JPS5988467A (ja) | 1982-11-09 | 1984-05-22 | Yoshitomi Pharmaceut Ind Ltd | フエノキシアミノプロパノ−ル誘導体 |
DK302185A (da) | 1984-07-05 | 1986-01-06 | Rolland Sa A | 2-amino-oxazoliner samt fremgangsmaade til deres fremstilling |
US4634689A (en) * | 1985-10-31 | 1987-01-06 | Schering Corporation | Phosphinylalkanoyl imino acids |
US4667038A (en) | 1985-12-02 | 1987-05-19 | Syntex (U.S.A.) Inc. | Tetrahydroisoquinoline derivatives |
US4792568A (en) | 1986-04-14 | 1988-12-20 | Rorer Pharmaceutical Corporation | Aryl pyrroles as useful antiallergy compounds |
JPS63126897A (ja) | 1986-05-02 | 1988-05-30 | Yoshitomi Pharmaceut Ind Ltd | 免疫抑制因子 |
US5135947A (en) | 1987-04-09 | 1992-08-04 | Eli Lilly And Company | 1-phenyl-3-naphthalenyloxypropanamines and their use as selective serotonin reuptake inhibitors |
GB8712694D0 (en) | 1987-05-29 | 1987-07-01 | Scras | Tetrahydrofurans etc |
IL86740A (en) | 1987-06-30 | 1992-11-15 | Tanabe Seiyaku Co | Thiphene derivatives,their preparation and pharmaceutical compositions containing them |
EP0300688A1 (en) | 1987-07-21 | 1989-01-25 | FISONS plc | Pyrrole derivatives, process for their preparation and pharmaceutical compositions containing them |
CA1334975C (en) | 1987-11-13 | 1995-03-28 | James H. Holms | Furan and pyrrole containing lipoxygenase inhibiting compounds |
US5039706A (en) * | 1987-11-30 | 1991-08-13 | Du Pont Merck Pharmaceutical Company | Antiinflammatory PLA2 inhibitors |
PT89239B (pt) | 1987-12-18 | 1993-07-30 | Glaxo Group Ltd | Processo para a preparacao de drivados de etanolamina |
US4977171A (en) | 1988-06-09 | 1990-12-11 | Yashima Chemical Industrial Co., Ltd. | Oxa- or thia-zoline derivative |
WO1990002727A1 (en) | 1988-09-14 | 1990-03-22 | Yoshitomi Pharmaceutical Industries, Ltd. | Immunosuppressant |
US5266599A (en) | 1989-02-20 | 1993-11-30 | Jouveinal S.A. | Use of (+)-1-[(3,4,5-trimethoxy)-benzyloxymethyl]-1-phenyl-N,N-dimethyl-n-propylamine to increase gastric discharge in a subject |
US5068247A (en) | 1989-07-07 | 1991-11-26 | Yoshitomi Pharmaceutical Industries, Ltd. | 2-aminopentanoic acid compounds and their use as immunosuppressants |
HU212415B (en) | 1989-08-25 | 1996-06-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing new cyclic oxym derivatives and pharmaceutical compositions containing them as active components |
US5234934A (en) | 1989-08-25 | 1993-08-10 | Egis Gyogyszergyar | Aminopropanol derivatives, process for their preparation and pharmaceutical compositions comprising the same |
FR2655043B1 (fr) | 1989-11-24 | 1992-02-07 | Adir | Nouveaux derives du thiophene, leur procede de preparation et les compositions pharmaceutiques les renfermant. |
US5037853A (en) | 1989-12-28 | 1991-08-06 | Abbott Laboratories | Cyclopropyl derivative lipoxygenase inhibitors |
GB9000644D0 (en) | 1990-01-11 | 1990-03-14 | Erba Carlo Spa | New ureido derivatives of poly-4-amino-2-carboxy-1-methyl compounds |
US5723218A (en) | 1990-04-16 | 1998-03-03 | Molecular Probes, Inc. | Dipyrrometheneboron difluoride labeled flourescent microparticles |
US5274113A (en) | 1991-11-01 | 1993-12-28 | Molecular Probes, Inc. | Long wavelength chemically reactive dipyrrometheneboron difluoride dyes and conjugates |
US5433896A (en) | 1994-05-20 | 1995-07-18 | Molecular Probes, Inc. | Dibenzopyrrometheneboron difluoride dyes |
US5326692B1 (en) | 1992-05-13 | 1996-04-30 | Molecular Probes Inc | Fluorescent microparticles with controllable enhanced stokes shift |
US5648270A (en) | 1995-02-06 | 1997-07-15 | Molecular Probes, Inc. | Methods of sensing with fluorescent conjugates of metal-chelating nitrogen heterocycles |
US5501980A (en) | 1994-05-20 | 1996-03-26 | Molecular Probes, Inc. | Benzazolylcoumarin-based ion indicators |
US5260322A (en) | 1990-10-08 | 1993-11-09 | Merck & Co., Inc. | Angiotension II antagonists in the treatment of hyperuricemia |
GB9027055D0 (en) | 1990-12-13 | 1991-02-06 | Sandoz Ltd | Organic compounds |
DK0492497T3 (da) | 1990-12-24 | 1997-01-06 | Hoechst Ag | Fremgangsmåde til acylering af alkoholer med en immobiliseret pseudomonas-lipase |
CA2071621C (en) | 1991-06-19 | 1996-08-06 | Ahihiko Hosoda | Aldehyde derivatives |
NL9101623A (nl) | 1991-09-26 | 1993-04-16 | Dsm Nv | Werkwijze voor de bereiding van een alcohol. |
ES2143993T3 (es) | 1991-12-11 | 2000-06-01 | Yoshitomi Pharmaceutical | Farmaco para tratar una enfermedad autoinmune. |
ATE154800T1 (de) | 1992-08-25 | 1997-07-15 | Searle & Co | N-(alkanoylamino-2-hydroxypropyl)-sulfonamide verwendbar als retrovirale proteaseninhibitoren |
ES2126658T3 (es) | 1992-10-21 | 1999-04-01 | Yoshitomi Pharmaceutical | Compuesto de 2-amino-1,3-propanodiol e inmunosupresor. |
US5288751A (en) | 1992-11-06 | 1994-02-22 | Abbott Laboratories | [(Substituted) phenyalkyl]furylalkynyl-and [substituted) phenyalkyl] thienylalkynyl-N-hydroxyurea inhibitors or leukotriene biosynthesis |
GB9304589D0 (en) | 1993-03-05 | 1993-04-21 | Erba Carlo Spa | Biologically active ureido derivatives useful as antimetastic agents |
GB9306473D0 (en) | 1993-03-29 | 1993-05-19 | Bioglan Lab Ltd | Pharmaceutically useful compounds |
US5837703A (en) | 1993-03-31 | 1998-11-17 | Cell Therapeutics, Inc. | Amino-alcohol substituted cyclic compounds |
US5641783A (en) | 1993-11-12 | 1997-06-24 | Cell Therapeutics, Inc. | Substituted amino alcohol compounds |
JPH06345728A (ja) | 1993-06-11 | 1994-12-20 | Nissan Chem Ind Ltd | N−置換アゾール誘導体の製造方法 |
US5717605A (en) * | 1993-10-14 | 1998-02-10 | Olympus Optical Co., Ltd. | Color classification apparatus |
US5534980A (en) * | 1994-05-31 | 1996-07-09 | Mita Industrial Co., Ltd. | Electrophotographic image forming apparatus having a charge removing means |
PT778263E (pt) * | 1994-08-22 | 2002-06-28 | Mitsubishi Pharma Corp | Composto de benzeno e sua utilizacao farmaceutica |
US5948820A (en) | 1994-08-22 | 1999-09-07 | Yoshitomi Pharmaceutical Industries, Ltd. | Benzene compound and pharmaceutical use thereof |
SI0812588T1 (en) | 1995-12-28 | 2005-02-28 | Mitsubishi Pharma Corporation | Pharmaceutical external preparations for topical administration comprising 2-amino-2-(2-(4-octylphenyl)ethyl)propane-1,3-diol for the treatment of diseases induced from immune disorder |
US6686353B1 (en) | 1996-05-20 | 2004-02-03 | Teijin Intellectual Property Center Limited | Diarylalkyl cyclic diamine derivatives as chemokine receptor antagonists |
US6476004B1 (en) | 1996-07-18 | 2002-11-05 | Mitsubishi Pharma Corporation | Pharmaceutical composition |
JPH11209277A (ja) | 1998-01-19 | 1999-08-03 | Yoshitomi Pharmaceut Ind Ltd | 医薬組成物 |
DE69734215T2 (de) | 1996-07-22 | 2006-06-29 | Novo Nordisk A/S | Verbindungen mit Wachstumshormon-freisetzenden Eigenschaften |
US6077954A (en) | 1996-08-01 | 2000-06-20 | Isis Pharmaceuticals, Inc. | Substituted heterocyclic compounds |
WO1998015278A1 (en) | 1996-10-07 | 1998-04-16 | Smithkline Beecham Corporation | Method for stimulating bone formation |
US5891892A (en) | 1996-10-29 | 1999-04-06 | Warner-Lambert Company | Small molecule biaryl compounds as inhibitors of endothelin converting enzyme |
GB9624038D0 (en) | 1996-11-19 | 1997-01-08 | Sandoz Ltd | Organic compounds |
US5732218A (en) * | 1997-01-02 | 1998-03-24 | Lucent Technologies Inc. | Management-data-gathering system for gathering on clients and servers data regarding interactions between the servers, the clients, and users of the clients during real use of a network of clients and servers |
ATE412407T1 (de) | 1997-02-27 | 2008-11-15 | Novartis Ag | Arzneimittel zubereitung enthaltend 2-amino-2-ä2- (4-octylphenyl)ethylüpropane-1,3-diol, ein lecithin und ein saccharid |
EP1319651B1 (en) | 1997-04-04 | 2005-06-29 | Mitsubishi Pharma Corporation | 2-Aminopropane-1,3-diol compound, pharmaceutical use thereof and synthetic intermediates therefor |
WO1999001420A1 (fr) | 1997-07-03 | 1999-01-14 | Taito Co., Ltd. | Procede de preparation de derives d'acide 2-aminomalonique, et intermediaires utilises dans ce procede |
NZ502872A (en) | 1997-08-28 | 2002-10-25 | Novartis Ag | Mevinolin and compaction as LFA-1 antagonists for treating autoimmune diseases |
JPH1180026A (ja) | 1997-09-02 | 1999-03-23 | Yoshitomi Pharmaceut Ind Ltd | 新規免疫抑制剤、その使用方法およびその同定方法 |
NZ504465A (en) | 1997-10-14 | 2001-11-30 | Welfide Corp | 1-Phenylacylamino substituted piperazine derivatives which are 4-substituted by a heteroaryl group |
DE19745904A1 (de) * | 1997-10-17 | 1999-04-22 | Hoechst Ag | Polymerstabilisierte Metallkolloid-Lösungen, Verfahren zu ihrer Herstellung und ihre Verwendung als Katalysatoren für Brennstoffzellen |
DE19817459A1 (de) | 1998-04-20 | 1999-10-21 | Basf Ag | Neue heterozyklische substituierte Amide, Herstellung und Anwendung |
CA2348879A1 (en) | 1998-11-02 | 2000-05-11 | Welfide Corporation | Pyrrolidine compound and pharmaceutical use thereof |
DK1129066T3 (da) | 1998-11-11 | 2005-03-29 | Novartis Ag | Fremstilling af 2-amino-2-[2-(C2-20alkylphenyl)ethyl]propan-1,3-dioler |
AU2164300A (en) | 1998-12-04 | 2000-06-26 | N.V. Organon | Substituted thiazoles for treatment of human diseases involving modulators of p-, l- and e- selectin |
US6525069B1 (en) | 1998-12-18 | 2003-02-25 | Bristol-Myers Squibb Pharma Co. | N-ureidoalkyl-piperidines as modulators of chemokine receptor activity |
KR20010101287A (ko) | 1998-12-18 | 2001-11-14 | 블레어 큐. 퍼거슨 | 케모킨 수용체 활성의 조절자로서 n-우레이도알킬-피페리딘 |
US6178821B1 (en) * | 1999-01-25 | 2001-01-30 | General Electric Company | Vibration sensing device |
NZ514095A (en) | 1999-02-10 | 2001-09-28 | Welfide Corp | Amide compounds and medicinal use thereof |
CN1144779C (zh) | 1999-03-11 | 2004-04-07 | 杭州中美华东制药有限公司 | 制备2-[2-(4-烷基苯基)-乙基]-2-氨基-丙二醇的方法以及其中制得的中间产物 |
JP4627356B2 (ja) | 1999-06-30 | 2011-02-09 | 松森 昭 | ウイルス性心筋炎の予防または治療薬剤 |
WO2001008685A1 (en) | 1999-07-30 | 2001-02-08 | Vertex Pharmaceuticals Incorporated | Acyclic and cyclic amine derivatives |
US6451830B1 (en) | 1999-09-23 | 2002-09-17 | G.D. Searle & Co. | Use of substituted N,N-disubstituted non-fused heterocyclo amino compounds for inhibiting cholesteryl ester transfer protein activity |
DE19963174A1 (de) * | 1999-12-27 | 2001-07-12 | Gruenenthal Gmbh | Substituierte Pyrrol-Mannichbasen |
ATE286051T1 (de) | 1999-12-31 | 2005-01-15 | Encysive Pharmaceuticals Inc | Sulfonamide und ihre derivate, die die aktivität des endothelins modulieren |
US6803375B1 (en) | 2000-01-06 | 2004-10-12 | The Regents Of The University Of California | Non-peptide inhibition of T-lymphocyte activation and therapies related thereto |
EA006079B1 (ru) | 2000-03-31 | 2005-08-25 | Пфайзер Продактс Инк. | Новые пиперазиновые производные |
US6964676B1 (en) * | 2000-04-14 | 2005-11-15 | Scimed Life Systems, Inc. | Stent securement system |
JP3942897B2 (ja) | 2000-04-28 | 2007-07-11 | エフ.ホフマン−ラ ロシュ アーゲー | p−(スルホニル)アリール及びヘテロアリール |
US6638950B2 (en) | 2000-06-21 | 2003-10-28 | Bristol-Myers Squibb Pharma Company | Piperidine amides as modulators of chemokine receptor activity |
EP1300405B1 (en) * | 2000-07-13 | 2007-04-18 | Sankyo Company, Limited | Amino alcohol derivatives |
JP2002053575A (ja) | 2000-08-09 | 2002-02-19 | Sankyo Co Ltd | アミノアルコ−ル類 |
JP2004507552A (ja) | 2000-08-31 | 2004-03-11 | メルク エンド カムパニー インコーポレーテッド | 免疫調節剤としてのリン酸誘導体 |
DE10049483A1 (de) | 2000-09-29 | 2002-05-02 | Gruenenthal Gmbh | Substituierte 1-Aminobutan-3-ol-Derivate |
DE10048714A1 (de) | 2000-09-30 | 2002-04-11 | Gruenenthal Gmbh | 5-Amino-1-penlen-3-ol-Derivate |
US20040087662A1 (en) | 2001-02-22 | 2004-05-06 | Marc Bigaud | Use of accelerated lymphocyte homing agents for the manufacture of a medicament for the treatment of delayed graft function |
ATE314383T1 (de) * | 2001-03-26 | 2006-01-15 | Novartis Pharma Gmbh | 2-amino-propanol derivate |
JP2002316985A (ja) | 2001-04-20 | 2002-10-31 | Sankyo Co Ltd | ベンゾチオフェン誘導体 |
ES2268044T3 (es) | 2001-05-21 | 2007-03-16 | Injet Digital Aerosols Limited | Composiciones para la administracion de proteinas por la via pulmonar. |
GB0117921D0 (en) | 2001-07-23 | 2001-09-12 | Novartis Ag | Organic compounds |
GB0119172D0 (en) | 2001-08-06 | 2001-09-26 | Melacure Therapeutics Ab | Phenyl pyrrole derivatives |
DE60223699T2 (de) | 2001-09-27 | 2008-10-30 | Kyorin Pharmaceutical Co., Ltd. | Diarylsulfidderivat, dessen additionssalz und immunsuppressivum |
US6963012B2 (en) | 2001-09-27 | 2005-11-08 | Kyorin Pharmaceutical Co., Ltd. | Diaryl ether derivative, addition salt thereof, and immunosuppressant |
GB0125443D0 (en) | 2001-10-23 | 2001-12-12 | Novartis Ag | Organic Compounds |
US7361671B2 (en) | 2001-11-15 | 2008-04-22 | The Institute For Pharmaceutical Discovery, Inc. | Substituted heteroarylalkanoic acids |
BR0214736A (pt) * | 2001-12-06 | 2004-11-23 | Elan Pharm Inc | Composto e seus sais farmaceuticamente aceitáveis, composição farmacêutica e método de tratar seres humanos ou animais que sofrem de doenças ou condições |
BR0306811A (pt) | 2002-01-11 | 2004-10-26 | Sankyo Co | Composto, éster farmacologicamente aceitável do mesmo, composição farmacêutica e métodos para prevenção ou tratamento de doenças autoimunes, da artrite reumatóide e da rejeição causada pelo transplante de vários órgãos em um mamìfero |
JP2003267974A (ja) | 2002-01-11 | 2003-09-25 | Sankyo Co Ltd | アミノアルコ−ル誘導体を含有する医薬組成物 |
US20040058894A1 (en) | 2002-01-18 | 2004-03-25 | Doherty George A. | Selective S1P1/Edg1 receptor agonists |
CA2483594C (en) | 2002-05-16 | 2011-02-15 | Novartis Ag | Use of edg receptor binding agents in cancer |
EP1539674A1 (en) | 2002-09-13 | 2005-06-15 | Novartis AG | Amino-propanol derivatives |
US20060046979A1 (en) | 2002-09-24 | 2006-03-02 | Foster Carolyn A | Organic compounds |
AU2005215320B2 (en) * | 2004-02-24 | 2008-04-17 | Sankyo Company, Limited | Amino alcohol compound |
TW200611687A (en) * | 2004-07-29 | 2006-04-16 | Sankyo Co | Pharmaceutical compositions used for immunosuppressant |
TWI418350B (zh) | 2005-06-24 | 2013-12-11 | Sankyo Co | 含有ppar調節劑之醫藥組成物的用途 |
-
2003
- 2003-01-09 BR BR0306811-0A patent/BR0306811A/pt active Pending
- 2003-01-09 SI SI200331668T patent/SI1471054T1/sl unknown
- 2003-01-09 CN CNB038059258A patent/CN100406437C/zh not_active Expired - Fee Related
- 2003-01-09 DE DE60328161T patent/DE60328161D1/de not_active Expired - Lifetime
- 2003-01-09 KR KR1020047010719A patent/KR100836547B1/ko not_active IP Right Cessation
- 2003-01-09 NZ NZ533994A patent/NZ533994A/xx not_active IP Right Cessation
- 2003-01-09 ES ES03701048T patent/ES2327825T3/es not_active Expired - Lifetime
- 2003-01-09 IL IL16287403A patent/IL162874A0/xx not_active IP Right Cessation
- 2003-01-09 KR KR1020087006865A patent/KR20080035702A/ko not_active Application Discontinuation
- 2003-01-09 RU RU2004121143/04A patent/RU2330839C2/ru not_active IP Right Cessation
- 2003-01-09 AU AU2003202495A patent/AU2003202495B2/en not_active Ceased
- 2003-01-09 WO PCT/JP2003/000136 patent/WO2003059880A1/ja active Application Filing
- 2003-01-09 DK DK03701048T patent/DK1471054T3/da active
- 2003-01-09 AT AT03701048T patent/ATE435202T1/de active
- 2003-01-09 EP EP03701048A patent/EP1471054B1/en not_active Expired - Lifetime
- 2003-01-09 PT PT03701048T patent/PT1471054E/pt unknown
- 2003-01-09 CA CA2473461A patent/CA2473461C/en not_active Expired - Fee Related
- 2003-01-09 MX MXPA04006709A patent/MXPA04006709A/es active IP Right Grant
- 2003-01-09 PL PL370790A patent/PL211954B1/pl unknown
- 2003-01-10 JP JP2003004599A patent/JP4270541B2/ja not_active Expired - Fee Related
- 2003-01-10 TW TW092100460A patent/TWI283574B/zh not_active IP Right Cessation
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2004
- 2004-07-12 CO CO04065919A patent/CO5640126A2/es active IP Right Grant
- 2004-07-12 US US10/889,657 patent/US7199150B2/en not_active Expired - Fee Related
- 2004-08-10 NO NO20043319A patent/NO329134B1/no not_active IP Right Cessation
- 2004-08-10 ZA ZA2004/06333A patent/ZA200406333B/en unknown
- 2004-11-30 HK HK04109418.1A patent/HK1066532A1/xx not_active IP Right Cessation
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2006
- 2006-12-11 US US11/636,776 patent/US20070105933A1/en not_active Abandoned
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2007
- 2007-01-09 US US11/651,205 patent/US7638551B2/en not_active Expired - Fee Related
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2009
- 2009-07-24 US US12/460,884 patent/US8067396B2/en not_active Expired - Fee Related
- 2009-08-12 US US12/583,001 patent/US8101650B2/en not_active Expired - Fee Related
- 2009-09-30 CY CY20091101015T patent/CY1109457T1/el unknown
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