CN1422655A - Throat lozenge - Google Patents

Throat lozenge Download PDF

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Publication number
CN1422655A
CN1422655A CN 02145514 CN02145514A CN1422655A CN 1422655 A CN1422655 A CN 1422655A CN 02145514 CN02145514 CN 02145514 CN 02145514 A CN02145514 A CN 02145514A CN 1422655 A CN1422655 A CN 1422655A
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China
Prior art keywords
drug
radix
buccal tablet
throat
messenger
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CN 02145514
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Chinese (zh)
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CN1221275C (en
Inventor
赵存梅
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XI'AN GAOKE SHANXI JINFANG PHARMACEUTICAL INDUSTRY Co
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XI'AN GAOKE SHANXI JINFANG PHARMACEUTICAL INDUSTRY Co
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Priority to CN 02145514 priority Critical patent/CN1221275C/en
Publication of CN1422655A publication Critical patent/CN1422655A/en
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Publication of CN1221275C publication Critical patent/CN1221275C/en
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Abstract

The lozenge with health-care functions of curing sore swollen throat, hoarse voice, coughing of phlegm is made from the Chinese medicinal materials of lonicera flower, chrysanthemum flower, dandelion, isatis root as main material and sterculia, oroxylum seed and dahurian angelica root as auxiliary material. Said lozenge possesses good therpaeutic effect, and also can be used as snack food.

Description

The throat buccal tablet
Technical field
The invention belongs to a kind of pharmaceutical product, a kind of specifically oral buccal tablet preparation that laryngopharyngeal diseases is had the control health-care effect based on Chinese medicine.
Technical background
Pharyngolaryngitis, laryngopharynx swelling and pain, hoarseness are that commonly encountered diseases is dyed in the impression of human body upper respiratory tract, at first are laryngopharynx swelling and pain when generally catching a cold, as long as the throat symptom can be eliminated, can play the elimination to the source, will prevent that upper respiratory tract infection from developing into General Symptoms.Therefore, prophylactic treatment throat symptom is most important to the treatment of respiratory infection diseases.
At present the pure Chinese medicine buccal tablet of treatment laryngopharyngeal diseases is more, but is medicine preparation, all plays therapeutical effect, lack a kind of can be used as that food commonly used consumes laryngopharyngeal diseases is had the buccal tablet of prevention and health-care effect.
Summary of the invention
The present invention seeks to adopt the integration of edible and medicinal herbs raw material, a kind of food that both can be used as is provided, again can throat buccal tablet simultaneously with health role.
Specifically, a kind of food that both can be used as of the present invention again can throat buccal tablet simultaneously with health role, by monarch drug, ministerial drug, adjuvant drug, messenger drug and flavoring agent by weight compatibility form, its composition is:
Monarch drug is: Flos Lonicerae, Flos Chrysanthemi, Herba Taraxaci, Radix Isatidis;
Ministerial drug is: Semen Sterculiae Lychnophorae, Semen Oroxyli, the Radix Angelicae Dahuricae;
Adjuvant drug can be treated the raw material of Chinese medicine of chronic cough, phlegm dyspnea, laryngopharynx swelling and pain for having out lung qi dispersing gas, nourishing YIN and moistening the lung, the chest stuffiness relieving, the relieving restlessness that clears away heart-fire, pain relieving Dingchuan, the effect of eliminating the phlegm;
Messenger drug is for having and middle emergency, the detoxifcation lung moistening, and coordinating the actions of various ingredients in a prescription, convergence is promoted the production of body fluid, and presses down equal antiallergic, nourishing YIN to lower pathogenic fire, the raw material of Chinese medicine of relieving restlessness detoxicating functions;
Flavoring agent is an amount of.
Adjuvant drug is Radix Platycodonis, Fructus Perillae, Caulis Perillae, Radix Ophiopogonis to consist of good.
Messenger drug consists of good with Fructus Mume, Radix Glycyrrhizae, pears, Radix Scrophulariae.
Flavoring agent is selected crystal sugar and Oleum menthae.
Key of the present invention is that monarch drug and ministerial drug are all chosen medicine food homologous raw materials, and the selection of adjuvant drug, messenger drug and flavoring agent is not very crucial, and the variation of each component content can be in a big way simultaneously.The each component weight portion of recommending is: monarch drug: Flos Lonicerae 120--180, Flos Chrysanthemi 100--140, Herba Taraxaci 160--240, Radix Isatidis 160-240; Ministerial drug: Semen Sterculiae Lychnophorae 120--140, Semen Oroxyli 120--140, Radix Angelicae Dahuricae 120--140; The adjuvant drug total amount is 320--480; The messenger drug total amount is 240--360; Flavoring agent is an amount of.
The adjuvant drug weight portion is: Radix Platycodonis 100--120, Fructus Perillae 90--110, Caulis Perillae 90--110, Radix Ophiopogonis 90--110.
The messenger drug weight portion is: Fructus Mume 90--110, Radix Glycyrrhizae 90-110, pears 90--110, Radix Scrophulariae 90--110.
The representative formula that the present invention recommends is:
Monarch drug: Flos Lonicerae 150, Flos Chrysanthemi 120, Herba Taraxaci 200, Radix Isatidis 200;
Ministerial drug: Semen Sterculiae Lychnophorae 100 Semen Oroxylis 100 Radixs Angelicae Dahuricae 100;
Adjuvant drug: Radix Platycodonis 120, Fructus Perillae 100, Caulis Perillae 100, Radix Ophiopogonis 100;
Messenger drug: Fructus Mume 100, Radix Glycyrrhizae 100, pears 100, Radix Scrophulariae 100;
Flavoring agent: crystal sugar is an amount of, Oleum menthae is an amount of
Flos Lonicerae in the prescription, Flos Chrysanthemi, Herba Taraxaci, Radix Isatidis have effects such as antiviral, heat reliving and toxin-eliminating.Can treat fever and cough, pneumonia, pharyngitis, laryngopharynx swelling and pain.Have out Radix Platycodonis, Fructus Perillae, Caulis Perillae, Radix Ophiopogonis that lung qi dispersing gas, nourishing YIN and moistening the lung, the chest stuffiness relieving, removing are tired, pain relieving Dingchuan, effect such as eliminate the phlegm.Can treat chronic cough, phlegm dyspnea, the stagnation of QI are uncomfortable in chest.Pears, crystal sugar, Semen Sterculiae Lychnophorae, Semen Oroxyli, the Radix Angelicae Dahuricae: heat-clearing and toxic substances removing, reducing swelling and alleviating pain, promoting the production of body fluid for nourishing the lung, sore-throat relieving, cough-relieving, Dingchuan, reduce phlegm, the chest stuffiness relieving.Can control phlegm dyspnea cough, laryngopharynx swelling and pain, hoarseness.Fructus Mume: the receipts sword promotes the production of body fluid, antibacterial antiallergic.Control chronic cough, laryngopharynx swelling and pain.Radix Glycyrrhizae: and middle emergency, detoxifcation lung moistening, coordinating the actions of various ingredients in a prescription.The Radix Scrophulariae nourishing YIN to lower pathogenic fire, relieving restlessness detoxifcation, is let out the fire of unrooted at the laryngopharynx swelling and pain that disappears, and controls calentura excessive thirst, laryngopharynx swelling and pain.
More than have heat-clearing and toxic substances removing, anti-bacteria and anti-virus, dispersing the stagnated liver-QI for regulating the stomach, nourishing YIN and moistening the lung, the chest stuffiness relieving behind all medicine compatibilities, eliminate the phlegm, sore-throat relieving, invigorate blood circulation, detumescence, hoarseness have the cleaning therapeutical effect, has the removing heat from the lung and relieving sorethroat protective effect to inhaling the pharynx crowd.
The present invention can be made into multiple dosage form.Wherein tablet manufacturing technology is:
1, extracts;
1. take by weighing Chinese crude drug by above recipe quantity, clean be soaked in water 30 minutes after, decocts three times, respectively 2,2,1h.Merge three times decocting liquid, being evaporated to relative density is 1.25-1.4 (60 ℃);
2. add ethanol to containing 60%, stir, left standstill 48 hours, the filtering precipitation, decompression recycling ethanol is standby to there not being the alcohol flavor;
3. relative density 1.25-1.4 (40 ℃) will be 2. be evaporated to, fluid extract must be extracted
Standby;
2, granulate: with fluid extract: crystal sugar: dextrin is used 18 orders by 1: 2: 1 system soft material
Granulate, in 50-80 ℃ of oven dry, granulate sprays into Oleum menthae and fully stirs evenly.
3, tabletting: fill tabletting promptly by every heavy 0.88-0.93.
The formula material of YANHOU PIAN of the present invention is one, two institutes of Pharmacopoeia of People's Republic of China version in 2000 and records, and major part is the rare Chinese medicine of medicine-food two-purpose, and adds an amount of flavoring agent, ample supply and prompt delivery.Ten multi-flavor medicines are pressed Chinese medicine monarch prescription, use modernization process, adopt nanotechnology, extract the active ingredient fluid extract,, be mixed with granule with other adjuvants again as binding agent, tabletting is made buccal tablet, containing slowly swallowed, and both can be used as leisure food, can play the effect of getting instant result by can be used as health product to pharyngitis, pain, hoarseness, phlegm dyspnea cough.So this product production put on market the back to vast throat patient and inhale pharynx crowd throat cleaning and health care many again new varieties.
Through laboratory test results, think that this product can kill 99.0% Staphylococcus aureus, escherichia coli, Candida albicans.Virulence test result, taking poison property of white mice acute oral LD50>5000mg/kg belong to nontoxic level; To White Rabbit tuerculoderma nonirritant.This product of above presentation of results meets the relevant hygiology index of country, and is safe in utilization.
Description of drawings:
Accompanying drawing is preparation technology's flow chart of the present invention.
The specific embodiment
Embodiment: an optimization formula of the present invention is:
Monarch drug: Flos Lonicerae 150, Flos Chrysanthemi 120, Herba Taraxaci 200, Radix Isatidis 200;
Ministerial drug: Semen Sterculiae Lychnophorae 100 Semen Oroxylis 100 Radixs Angelicae Dahuricae 100;
Adjuvant drug: Radix Platycodonis 120, Fructus Perillae 100, Caulis Perillae 100, Radix Ophiopogonis 100;
Messenger drug: Fructus Mume 100, Radix Glycyrrhizae 100, pears 100, Radix Scrophulariae 100;
Flavoring agent: crystal sugar is an amount of, Oleum menthae is an amount of
Production technology is:
1, extract:
1. take by weighing Chinese crude drug by above recipe quantity, clean be soaked in water 30 minutes after, decocts three times, respectively 2,2,1h.Merge three times decocting liquid, being evaporated to relative density is 1.25-1.4 (60 ℃).
2. add ethanol to containing 60%, stir, left standstill 48 hours, the filtering precipitation, decompression recycling ethanol is standby to there not being the alcohol flavor.
3. relative density 1.25-1.4 (40 ℃) will be 2. be evaporated to, fluid extract must be extracted
Standby.
2, granulate: with fluid extract: crystal sugar: dextrin is by 1: 2: 1 system soft material, with 18
Order is granulated, and in 50-80 ℃ of oven dry, granulate sprays into Oleum menthae and fully stirs evenly.
3, tabletting: fill tabletting promptly by every heavy 0.88-0.93.

Claims (10)

1, a kind of food that both can be used as again can throat buccal tablet simultaneously with health role, is formed by monarch drug, ministerial drug, adjuvant drug, messenger drug and flavoring agent compatibility, it is characterized in that:
Monarch drug is: Flos Lonicerae, Flos Chrysanthemi, Herba Taraxaci, Radix Isatidis;
Ministerial drug is: Semen Sterculiae Lychnophorae, Semen Oroxyli, the Radix Angelicae Dahuricae;
Adjuvant drug can be treated the raw material of Chinese medicine of chronic cough, phlegm dyspnea, laryngopharynx swelling and pain for having out lung qi dispersing gas, nourishing YIN and moistening the lung, the chest stuffiness relieving, the relieving restlessness that clears away heart-fire, pain relieving Dingchuan, the effect of eliminating the phlegm;
Messenger drug is for having and middle emergency, the detoxifcation lung moistening, and coordinating the actions of various ingredients in a prescription, convergence is promoted the production of body fluid, and presses down equal antiallergic, nourishing YIN to lower pathogenic fire, the raw material of Chinese medicine of relieving restlessness detoxicating functions;
Flavoring agent is an amount of.
2, throat buccal tablet according to claim 1 is characterized in that adjuvant drug is: Radix Platycodonis, Fructus Perillae, Caulis Perillae, Radix Ophiopogonis.
3, throat buccal tablet according to claim 1 is characterized in that messenger drug is: Fructus Mume, Radix Glycyrrhizae, pears, Radix Scrophulariae.
4, throat buccal tablet according to claim 1 is characterized in that flavoring agent is: crystal sugar and Oleum menthae.
5, throat buccal tablet according to claim 1 is characterized in that the each component weight portion is: monarch drug: Flos Lonicerae 120--180, Flos Chrysanthemi 100--140, Herba Taraxaci 160--240, Radix Isatidis 160--240; Ministerial drug: Semen Sterculiae Lychnophorae 120--140, Semen Oroxyli 120--140, Radix Angelicae Dahuricae 120--140; The adjuvant drug total amount is 320--480; The messenger drug total amount is 240--360; Flavoring agent is an amount of.
6, according to claim 2,5 described throat buccal tablets, it is characterized in that the adjuvant drug weight portion is: Radix Platycodonis 100--120, Fructus Perillae 90--110, Caulis Perillae 90--110, Radix Ophiopogonis 90--110.
7, according to claim 3,5 described throat buccal tablets, it is characterized in that the messenger drug weight portion is: Fructus Mume 90--110, Radix Glycyrrhizae 90--110, pears 90-110, Radix Scrophulariae 90--110.
8, throat buccal tablet according to claim 5 is characterized in that each component weight is divided into:
Monarch drug: Flos Lonicerae 150, Flos Chrysanthemi 120, Herba Taraxaci 200, Radix Isatidis 200; Ministerial drug: Semen Sterculiae Lychnophorae 100, Semen Oroxyli 100, the Radix Angelicae Dahuricae 100; The adjuvant drug total amount is 320--480; The messenger drug total amount is 240--360; Flavoring agent is an amount of.
9, throat buccal tablet according to claim 6 is characterized in that the adjuvant drug weight portion is:
Radix Platycodonis 120, Fructus Perillae 100, Caulis Perillae 100, Radix Ophiopogonis 100.
10, throat buccal tablet according to claim 7 is characterized in that the messenger drug weight portion is: Fructus Mume 100, Radix Glycyrrhizae 100, pears 100, Radix Scrophulariae 100.
CN 02145514 2002-12-04 2002-12-04 Throat lozenge Expired - Fee Related CN1221275C (en)

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Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100350948C (en) * 2004-05-15 2007-11-28 赵存梅 Compound throat sucking-tablet of semen sterculiae scaphigerae and oral tonic thereof
CN103720957A (en) * 2013-12-31 2014-04-16 芜湖乐锐思信息咨询有限公司 Chinese medicinal formula for treating adenoidal hypertrophy and preparation method thereof
CN106615531A (en) * 2016-09-27 2017-05-10 合肥智博生物科技有限公司 Throat-clearing and sore-throat-relieving candies and preparation method thereof
CN110522823A (en) * 2019-09-17 2019-12-03 大连民族大学 A kind of preparation method of pure natural dark green tea lozenge
CN110559366A (en) * 2019-09-17 2019-12-13 大连民族大学 Dark green tea buccal tablet with tooth-protecting and sore-throat-relieving effects

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101912112A (en) * 2010-07-23 2010-12-15 江苏老蚕坊蚕桑生物科技开发有限公司 Method for manufacturing compound mulberry leaf throat moistening and cleaning tablet

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN100350948C (en) * 2004-05-15 2007-11-28 赵存梅 Compound throat sucking-tablet of semen sterculiae scaphigerae and oral tonic thereof
CN103720957A (en) * 2013-12-31 2014-04-16 芜湖乐锐思信息咨询有限公司 Chinese medicinal formula for treating adenoidal hypertrophy and preparation method thereof
CN106615531A (en) * 2016-09-27 2017-05-10 合肥智博生物科技有限公司 Throat-clearing and sore-throat-relieving candies and preparation method thereof
CN110522823A (en) * 2019-09-17 2019-12-03 大连民族大学 A kind of preparation method of pure natural dark green tea lozenge
CN110559366A (en) * 2019-09-17 2019-12-13 大连民族大学 Dark green tea buccal tablet with tooth-protecting and sore-throat-relieving effects

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