CN1150927C - Stomatopathy and throat disease treating health care medicine and its production process - Google Patents

Stomatopathy and throat disease treating health care medicine and its production process

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Publication number
CN1150927C
CN1150927C CNB011283467A CN01128346A CN1150927C CN 1150927 C CN1150927 C CN 1150927C CN B011283467 A CNB011283467 A CN B011283467A CN 01128346 A CN01128346 A CN 01128346A CN 1150927 C CN1150927 C CN 1150927C
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weight
medicinal residues
mel
hour
extract
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CN1335174A (en
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吴观秀
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Abstract

The present invention provides a health care medicine for treating oral cavity and throat diseases, and the production method of the health care medicine. The health care medicine comprises the traditional Chinese medicine raw materials of honeysuckle, chrysanthemum, dyers woad root, oldenlandia, balloonflower root, periostracum cicadae, scaly holly root, dandelion, licorice root, etc. The production method of the present invention comprises the steps: the nine kinds of traditional Chinese medicine raw materials excluding honey are washed, pulverized and sieved by 200 meshes to be fabricated into medicinal powder, or the effective components are extracted by an ethanol extraction method and a water extraction method to be fabricated into oral liquid, buccal tablets, tablets, capsule preparations, capsules and pills. The health care medicine can eliminate inflammation caused by every liver pathogenic toxin in a human body, and can treat oral cavity and throat diseases, such as laryngopharyngitis, tonsillitis, ulceratiue stomatitis, gingivitis, upper respiratory tract infection, etc.

Description

A kind of treatment acute and chronic pharyngitis, tonsillitic medicine and production method thereof
Technical field
The present invention relates to a kind of treatment oral cavity and laryngopharyngeal diseases such as pharyngolaryngitis, tonsillitic Chinese medicine and production method thereof.
Background technology
Pharyngolaryngitis, tonsillitis is human commonly encountered diseases, high morbidity, its main cause has multiple, wherein great majority are the intestines and stomach intenseness of heat, retention of heat in the spleen and stomach causes, be embodied in red swelling and pain of throat or fester, the tonsil inflammation is hemorrhage, dry tongue halitosis etc., got gently dysphagia then of these sick patients, heavy then hyperpyrexia is had a headache, routine work and life have been influenced, for these treatment of conditions, doctor trained in Western medicine is mainly taked eliminating inflammation and expelling toxin medicine for oral administration at present, antibiotics, or injection penicillin, erythromycin, the treatment of antibiotic medicine such as cephalo ammonia Bian, the traditional Chinese medical science mainly adopts has heat-clearing and toxic substances removing, the medicine of removing heat from blood lung heat clearing is treated, as Flos Lonicerae, Fructus Forsythiae, Herba Violae, Fructus Canarii, Rhizoma Imperataes etc. have also been sold some in the market and have been treated the Chinese medicine preparation or the buccal tablet of laryngopharyngeal diseasess, as Herba Pileae Scriptae Tabellae, watermelon crystal, JINSANGZIHOUBAO etc., these Chinese medicine preparation have played certain effect to slowing down some throat disease, but great majority only play the effect that palliates a disease, and can not cure the heavier patient of the state of an illness internally quickly, suffer from throat, the oral cavity critically ill patient must rely on heavy dose of antibiotics western medicine, and heavy dose of bacteriophage on human body produces some side effect to a certain extent.
In recent years, public publication is as " Chinese medicine ", and " Chinese herbal medicine " waits the medicine of also reporting many treatments oral cavity and laryngopharyngeal diseases on some magazines, Chinese patent 94112228 discloses with Radix Platycodonis, Radix Glycyrrhizae, Flos Lonicerae, Flos Chrysanthemi, Herba Menthae, FRUCTUS TERMINALIAE IMMATURUS or semen sterculiiae lychnophorae, green tea, Gan Yeju are that the Chinese medicine bag of Main Ingredients and Appearance is made tea, to the treatment pharyngalgia, hoarseness has certain effect; Chinese patent 97111786 also discloses a kind of cleaning throat and moistening larynx eliminating inflammation and expelling toxin beverage, form by Fructus Crataegi, Flos Chrysanthemi, Fructus Lycii, Flos Lonicerae, Fructus Schisandrae Chinensis, Radix Glycyrrhizae and Mel or white sugar, pure water, can heat-clearing and toxic substances removing, cleaning throat and moistening larynx, play certain antiinflammatory, antidotal purpose.
The treatment oral cavity of selling on above-mentioned open source literature and the market and the Chinese medicine of laryngopharyngeal diseases or beverage great majority can only take stopgap measures, and can not effect a permanent cure, and particularly can not treat the state of an illness and increase the weight of, and cause headache, heating, the patient of general malaise.
Technology contents
In order to treat oral cavity and laryngopharyngeal diseases better, the inventor is from the prescription of tradition Chinese herbal treatment among the people, through discovery and arrangement, experiment repeatedly, contrast, and by modern detection and treatment means, sum up a kind of to treating the Chinese herbal and crude drugs preparations of common acute and chronic pharyngitis, tonsillitis disease, and make with modern pharmaceutical technology, to medium-height grass treatment oral cavity, laryngopharyngeal diseases provides a kind of new good health care medicine.
Medicine of the present invention is to be made by the raw material of following weight parts:
Flos Lonicerae 10---15
Flos Chrysanthemi 8---10
Radix Isatidis 15---30
Herba Hedyotidis Diffusae 5---10
Radix Platycodonis 5---10
Periostracum Cicadae 3---6
Flos Ilicis Asprellae 15---30
Herba Taraxaci 10---15
Mel 15---20
Radix Glycyrrhizae 3---6
The performance and the effectiveness of above-mentioned each composition of Chinese medicine are as follows:
Flos Lonicerae (having another name called Flos Lonicerae), sweet in flavor and cold in property, effectiveness: heat-clearing and toxic substances removing, card is controlled heating, headache, pharyngalgia, dermexanthesis, dysentery etc. are according to the research of modern Chinese medicine pharmacology.Flos Lonicerae has stronger antibacterial action to dysentery bacterium, Bacillus typhi, cholera bacteria, escherichia coli, bacillus pyocyaneus, staphylococcus aureus, Hemolytic streptococcus, Diplococcus pneumoniae, bordetella pertussis etc., bright product mashes to apply ointment or plaster and can control suppurative wound, carbuncle etc., as with Radix Et Rhizoma Rhei, Fructus Forsythiaes etc. share, and can treat tonsillitis, stomatitis, upper respiratory tract infection.
Radix Isatidis flavor property bitter cold, effectiveness heat clearing away, removing heat from blood, detoxifcation, card control that warm epidemic disease poison, rotten larynx erythema, larynx fraud swell and ache, warm malicious macule, cheek inflammation etc.According to modern pharmacological research, Radix Isatidis all has antibacterial action to Gram-negative and positive bacteria.
Flos Chrysanthemi, nature and flavor sweetness and bitterness is cold, card controls that affection due to external wind and heat, fever and headache, pyretic toxicity pent up, the carbuncle furuncle, according to modern pharmacological research, Flos Chrysanthemi has the effect of Chinese People's Anti-Japanese Military and Political College enterobacteria, Bacillus typhi, Salmonella paratyphi, bacillus pyocyaneus, comma bacillus, staphylococcus aureus and beta hemolytic streptococcus, fungus.
Herba Hedyotidis Diffusae, the cold of property slightly sweet flavor, cures mainly jaundice, pharyngalgia tumor, furuncle carbuncle, gonorrhea, traumatic injury, venom at effectiveness heat-clearing and toxic substances removing, diuresis of blood circulation promoting.
Radix Platycodonis, nature and flavor toil tepor, effectiveness eliminating phlegm and stopping cough, lung qi dispersing evacuation of pus, card is controlled pyretic toxicity and is stopped up swollen, lung abscess, septum pectorale completely pain, cough a lot of phlegm, the dense infections of surgery, and according to modern pharmacological research, the contained Radix Platycodonis soap of Radix Platycodonis can promote the secretion of trachea, truly has the antiinflammatory expectorant effect.
Periostracum Cicadae, nature and flavor are salty do cold, effectiveness loose wind heat clearing away, lung qi dispersing rash, spasmolytic, removing nebula to improve visual acuity, card is controlled the strongly fragrant lung of wind heat, the hoarseness of coughing, have sore throat, the strongly fragrant table of wind heat, rubella, measles, skin itching.
Herba Taraxaci, the property bitter but sweet flavor is cold, and effectiveness heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, disease are controlled hyperactivity of toxic heat, acute mastitis swells and ache, treats poison, carbuncle, conjunctival congestion and swelling pain, according to theory of Chinese medical science research, but Herba Taraxaci heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, Orally taken and externally is all powerful.
Flos Ilicis Asprellae, property mildly bitter flavor, little sweet cold, cure mainly influenza, fever, acute tonsillitis, pharyngolaryngitis, traumatic injury, furuncle carbuncle at effectiveness heat-clearing and toxic substances removing, the dissipating blood stasis of subsiding a swelling.
Radix Glycyrrhizae, sweet flat, the moxibustion of nature and flavor is a tepor, and effectiveness invigorating the spleen and replenishing QI, lung moistening are eliminated the phlegm, heat-clearing and toxic substances removing, coordinating the actions of various ingredients in a prescription, and card is controlled cough and asthma, throat toxic swelling, carbuncle skin infection, fire-toxin and is stopped up and stagnate.
Mel, nature and flavor are sweet flat, the effectiveness invigorating middle warmer pain relieving of moisturizing, detoxify, disease is controlled deficiency of YIN of the spleen and stomach, dryness of the intestine constipation, the dryness of the lung is thanks to cloudy and as harmonizing drug
Above-mentioned ten kinds of Chinese herbal medicine all are heat and toxic materials clearing away medicine, and the anti-various bacteria of most of energy is to laryngopharynx swelling and pain, oral ulcer all has therapeutical effect, can take into account after they are made into comprehensively, produces synergism, curative effect is obvious, and it is applicable to acute and chronic pharyngitis, the enlargement of acute and chronic tonsillitis Dui Jaw submental lymph nodes, oral ulcer, aphtha of the mouth and tongue, red swelling of gingiva, scorching hot dry cough in the larynx is had sore throat, and diseases such as upper respiratory tract infection also have therapeutic effect.
Medicine of the present invention can be made preparations such as medicated powder, concentrated medicament, capsule, tablet, buccal tablet, pill as required, below is production method:
The production method of medicated powder:
In proportion above-mentioned nine kinds of Chinese herbal medicine except Mel are cleaned, pulverizing is also crossed 200 mesh sieves, with paper bag or plastic bag packing, refills box, adds the Mel decoction when ill, perhaps mixes with Folium Camelliae sinensis, is distributed into 1-2 with paper bag and restrains a bag, as the teabag Instant Drinks.
The production method of concentrated medicament:
In proportion above-mentioned nine kinds of Chinese herbal medicine except Mel are cleaned, pulverize and cross 200 mesh sieves, by medicated powder weight, ethanol with 2-3 times of weight 50-90% extracted 1-2 hour in the backflow hermetic container earlier, filter out medicinal residues, obtain alcohol extract, add the water purification of 3-5 times of weight again by medicinal residues weight, boiled 1-2 hour with slow fire, leaching medicinal residues discards, obtain the water extract, merge alcohol extract and water extract, reclaim ethanol with the way of distillation, add Mel again, bottling, sterilization obtain product, this product called after " the celestial spirit of larynx " medicinal liquid.
When lacking refluxing unit and distillation equipment, also can boil 2-3 elimination and shake slag with water purification, merge medicinal liquid, reconcentration to water content is the concentrated medicament of 30-50%, adds Mel again, bottling, sterilization obtain product.
The production method of capsule and tablet:
Method by above-mentioned production concentrated medicament makes alcohol extract and water extract earlier, further concentrates, and adds Mel and filling material, and tabletting or incapsulate obtains product, this product called after " the celestial spirit of larynx " tablet or " the celestial spirit of larynx " capsule.
The production method of buccal tablet:
In proportion above-mentioned nine kinds of Chinese herbal medicine except Mel are cleaned, pulverize and cross 200 mesh sieves, by medicated powder weight, ethanol with 2-3 times of weight 50-90% extracted 1-2 hour in the backflow hermetic container earlier, filter out medicinal residues, obtain alcohol extract, add the water purification of 3-5 times of weight again by medicinal residues weight, boiled 1-2 hour with slow fire, leaching medicinal residues discards, obtain the water extract, merge alcohol extract and water extract, reclaim ethanol with the way of distillation, add Mel, further concentrate, add Herba Menthae and white sugar again, make buccal tablet.
The production method of pill:
Method by above-mentioned production concentrated medicament makes alcohol extract and water extract earlier, further concentrates, and adds Mel and filling material, makes pill and obtains product, this product called after " the celestial spirit of larynx " pill.
Pharmacological effect: medicine of the present invention can be eliminated the inflammation that the evil poison of each internal organs causes in the human body, more can regulate each internal organs nervous system running balance in the human body, can also health invigorating and improve immunity, have heat-clearing and toxic substances removing, yin nourishing pathogenic fire reducing, depressed liver-energy dispersing and QI regulating, stomach function regulating spleen invigorating, damp eliminating antiinflammatory, sterilization, detumescence, pain relieving, antipruritic, reduce phlegm, effects such as sound producing and blood fat reducing.
The present invention compared with the prior art, substantive distinguishing features that it is outstanding and obvious improvement are beneficial to health, can win victory with unique drug effect of quick-acting specially good effect treating both the principal and the secondary aspects of a disease at the same time, no matter be acute or chronic, can both thoroughly effecting a radical cure of many years ago or recent morbidity, its special advantages is arranged, be subjected to liking and praising of patient deeply.Compare, control throat disease medicine such as tablet more than on the current market, the capsule spray, all kinds such as agent that wet one's whistle, taking stopgap measures can be good, but it is not good enough to effect a permanent cure, just differ widely and moisten celestial spirit, the inflammation that the evil poison of each internal organs causes in the human body is eliminated in the scientific composition treating both the principal and the secondary aspects of a disease at the same time, more can regulate the interior five hollow organs six dirty central nervous system of human body and operate balance, can also health invigorating and raising immunologic function.
Medicine of the present invention can be eliminated the inflammation that the evil poison of each internal organs causes in the human body, can also treat oral disease such as oral ulcer, gingivitis, upper respiratory tract infection.
In addition, what medicine of the present invention adopted all is common Chinese herbal medicine, without any side effects.
Concentrated medicament of the present invention carries out acute toxicity test by the provincial college of traditional Chinese medicine, and concrete grammar and result are as follows:
Summary: the celestial clever herb liquid The acute toxicity tests of larynx shows that give the Kunming mouse gastric infusion for reagent, maximum tolerated dose (MTD) is the 500g crude drug.Press 60kg/ people and calculate, 2 times/day, 50g/ time, promptly be equivalent to 300 times of the clinical consumption per day of people.
Test sample: the celestial medicine liquid of larynx, adopt the celestial medicine liquid of the well-done larynx of 6 bags to be total to 1050ml and be concentrated into 105ml (promptly 10: 1) in water-bath
The animal experiment condition: Kunming mouse, regular grade, male and female half and half, body weight 18-22g is provided by Colleges Of Traditional Chinese Medicine Of Guangxi, the animal quality certification number: No. the 1104th, the moving word of osmanthus doctor.
Test method and result: get 20 of Kunming mouses, each 10 of male and female, fasting is after 12 hours, give for reagent 0.5ml/10g/ time, gastric infusion is every 4 hours times, totally 4 times, total dosage is 500g crude drug/kilogram, observes signs of toxicity and the death condition of animal after the administration.
The result: after the administration in 7 days mice movable normal, no abnormality seens such as animal appearance, behavior, feed, the activity of observation extremity, breathing and defecation, animal hair is bright and clean, after 2 male and 7 female mice self administration of medication are arranged, go out to advise the soft stool in 8 hours, other index is all normal, does not see dead the generation.Male mouse weightening finish 2.95 ± 1.3g after the administration, rate of body weight gain is 15.82%.Female Mus weightening finish 4.40 ± 1.13g, rate of body weight gain is 22.17%.
Conclusion: give mouse stomach administration (ig) with test sample, maximum tolerated dose (MDT) is 500/kg, is limited to the administration capacity of drug level and animal, can't measure LD 50The celestial clever herb liquid toxicity of larynx that shows censorship is low.
The specific embodiment
Embodiment 1
With dried medical material Flos Lonicerae 12 grams, Flos Chrysanthemi 8 grams, Radix Isatidis 25 grams, Herba Hedyotidis Diffusae 8 grams, Radix Platycodonis 5 grams, Periostracum Cicadae 4 grams, Flos Ilicis Asprellae 20 grams, Herba Taraxaci 12 grams, Radix Glycyrrhizae 3 grams were pulverized 200 mesh sieves, ethanol with 2-3 times of weight 50-90% extracted 1-2 hour in the backflow hermetic container earlier, filter out medicinal residues, obtain alcohol extract, add the water purification of 3-5 times of weight again by medicinal residues weight, boiled 1-2 hour with slow fire, leach medicinal residues and discard, obtain the water extract, merge alcohol extract and water extract, reclaim ethanol with the way of distillation, add Mel 16 grams again, bottling, sterilization obtains " the celestial spirit of larynx " medicinal liquid product.
Embodiment 2
With dried medical material Flos Lonicerae 15 grams, Flos Chrysanthemi 9 grams, Radix Isatidis 20 grams, Herba Hedyotidis Diffusae 7 grams, Radix Platycodonis 8 grams, Periostracum Cicadae 5 grams, Flos Ilicis Asprellae 30 grams, Herba Taraxaci 15 grams, Radix Glycyrrhizae 4 grams, pulverized 200 mesh sieves,, refilled box, and added the Mel decoction when ill or take after mixing it with water with paper bag or plastic bag packing.
Embodiment 3
With dried medical material Flos Lonicerae 14 grams, Flos Chrysanthemi 8 grams, Radix Isatidis 28 grams, Herba Hedyotidis Diffusae 10 grams, Radix Platycodonis 6 grams, Periostracum Cicadae 6 grams, Flos Ilicis Asprellae 25 grams, Herba Taraxaci 15 grams, Radix Glycyrrhizae 5 grams, pulverized 200 mesh sieves, the ethanol with 2-3 times of weight 50-90% extracted 1-2 hour in the backflow hermetic container earlier, filtered out medicinal residues, obtain alcohol extract, add the water purification of 3-5 times of weight again by medicinal residues weight, boiled 1-2 hour, leach medicinal residues and discard with slow fire, obtain the water extract, merge alcohol extract and water extract, reclaim ethanol, further concentrate with the way of distillation, add Mel 18 gram and filling materials again, tabletting or incapsulate obtains product, this product called after " the celestial spirit of larynx " tablet or " the celestial spirit of larynx " capsule.
Embodiment 4
With dried medical material Flos Lonicerae 12 grams, Flos Chrysanthemi 9 grams, Radix Isatidis 23 grams, Herba Hedyotidis Diffusae 9 grams, Radix Platycodonis 6 grams, Ticks is sloughed off 5 grams, Flos Ilicis Asprellae 25 grams, Herba Taraxaci 15 grams, Radix Glycyrrhizae 5 grams, pulverized 200 mesh sieves, the ethanol with 2-3 times of weight 50-90% extracted 1-2 hour in the backflow hermetic container earlier, filtered out medicinal residues, obtain alcohol extract, add the water purification of 3-5 times of weight again by medicinal residues weight, boiled 1-2 hour, leach medicinal residues and discard with slow fire, obtain the water extract, merge alcohol extract and water extract, reclaim ethanol, further concentrate with the way of distillation, add Mel 18 grams again, Herba Menthae 1-2 gram, sucrose 100 grams are made buccal tablet.
Using method;
Two and one oral liquid, three bottles of oral liquids of every box and 18 buccal tablets.200 milliliters every bottle, buccal tablet 1g/ grain, one bottle of per day for adults clothes, 6 of buccal tablets, infant is obeyed 1/4 bottle every day, 3 of buccal tablets, obey 1/2 bottle 2 every days one full year of life one full year of life to 5,3 of buccal tablets, and obey 3/4 bottle 6 every days one full year of life one full year of life to 10,6 of buccal tablets, obey one bottle above every day of 11 one full year of life, 6 of buccal tablets, as long as obey oral liquid once, buccal tablet 3 every day---6, take before sleeping after the supper, serve on three days, can thoroughly fully recover.
The medicated powder using method; Every box has three bottles of medicated powder, every bottle 40 gram, and one bottle of per day for adults clothes, infant is obeyed 1/3 bottle every day; Obey 1/2 bottle 2 every days one full year of life one full year of life to 5, and obey 1 bottle 6 every days one full year of life one full year of life to 10, serve on three days once a day, can thoroughly fully recover.
The treatment example:
1, thanks * *, man, 30 years old, the workman, people from Zhanjiang City, Guangdong Province requires the inventor's diagnosis and treatment July nineteen ninety-five, symptom is a hoarseness, and is scorching hot in the larynx, itching of the throat dry cough, body temperature 39 degree are acute laryngitis after diagnosing, give medicine of the present invention " the celestial spirit of larynx " medicinal liquid treatment, took medicine after the supper 200 milliliters the same day, and the hoarseness symptom is clearly better, and pronunciation smoothly, scorching hot red and swollen disappearance the in the larynx, body temperature is normal.In order to consolidate curative effect, serve on two days, every day twice, thoroughly recovery from illness.
2, poplar * *, woman, 33 years old, the peasant, Huang Po people from town in Wuchuan City, Guangdong Province is according to telling: the stupid disease of throat, often outbreak repeatedly needs the refrigerant buccal tablet of informal dress, use the antibiotic medicine, spray etc., and often cat fever, headache appears, thirsty, chest pain, symptoms such as inappetence, found itching of the throat dry cough the same day, hoarseness, short breath, the throat redness, swallow pain, antiadoncus is treated the commentaries on classics of not getting better to clinic, the place requires diagnosis and treatment July nineteen ninety-five to the inventor, be diagnosed as chronic laryngopharyngitis, give medicine of the present invention " the celestial spirit of larynx " medicinal liquid treatment, the 200 milliliters of headaches of taking medicine the same day, thirsty, chest pain, symptoms such as itching of the throat dry cough are clearly better, appetite in second day takes a turn for the better, take medicine twice again, tonsil dwindles, and takes medicine three days, it is normal that tonsil recovers, red and swollen all disappearances in the larynx, thoroughly recovery from illness is followed up a case by regular visits to and was not seen recurrence in 5 years, healthy, 15 kilograms of weight increase.
3, Wu * *, woman, 7 years old,, Wuchuan City, Guangdong Province Huang Po people from town, cat fever two days, body temperature 39 degree, the throat congestion and swelling pain is in diagnosis and treatment in July calendar year 2001, take " the celestial spirit of larynx " tablet, every day twice, each two, the cat fever transference cure, body temperature is normal, and throat congestion and swelling pain symptom also all disappears, and has no adverse reaction.

Claims (6)

1, a kind of treatment acute and chronic pharyngitis, tonsillitic medicine is characterized in that it is to be made by the raw material of following weight parts:
Flos Lonicerae 10---15
Flos Chrysanthemi 8---10
Radix Isatidis 15---30
Herba Hedyotidis Diffusae 5---10
Radix Platycodonis 5---10
Periostracum Cicadae 3---6
Flos Ilicis Asprellae 15---30
Herba Taraxaci 10---15
Mel 15---20
Radix Glycyrrhizae 3---6
2, a kind of treatment acute and chronic pharyngitis as claimed in claim 1, tonsillitic medicine production method, it is characterized in that: in proportion above-mentioned nine kinds of Chinese herbal medicine except Mel are cleaned, pulverizing is also crossed 200 mesh sieves, makes medicated powder, perhaps mix, make tea beverage with Folium Camelliae sinensis.
3, a kind of treatment acute and chronic pharyngitis as claimed in claim 1, tonsillitic medicine production method, it is characterized in that: in proportion above-mentioned nine kinds of Chinese herbal medicine except Mel are cleaned, pulverize and cross 200 mesh sieves, by medicated powder weight, ethanol with 2-3 times of weight 50-90% extracted 1-2 hour in the backflow hermetic container earlier, filter out medicinal residues, obtain alcohol extract, add the water purification of 3-5 times of weight again by medicinal residues weight, boiled 1-2 hour with slow fire, leach medicinal residues and discard, obtain the water extract, merge alcohol extract and water extract, reclaim ethanol with the way of distillation, add Mel again, bottling, sterilization obtains medicinal liquid.
4, a kind of treatment acute and chronic pharyngitis as claimed in claim 1, tonsillitic medicine production method, it is characterized in that: in proportion above-mentioned nine kinds of Chinese herbal medicine except Mel are cleaned, pulverize and cross 200 mesh sieves, by medicated powder weight, ethanol with 2-3 times of weight 50-90% extracted 1-2 hour in the backflow hermetic container earlier, filtered out medicinal residues, obtained alcohol extract, the water purification that adds 3-5 times of weight again by medicinal residues weight, boiled 1-2 hour with slow fire, leach medicinal residues and discard, obtain the water extract, merge alcohol extract and water extract, reclaim ethanol with the way of distillation, further concentrate, add Mel and filling material again, tabletting or incapsulate obtains product.
5, a kind of treatment acute and chronic pharyngitis as claimed in claim 1, tonsillitic medicine production method, it is characterized in that: in proportion above-mentioned nine kinds of Chinese herbal medicine except Mel are cleaned, pulverize and cross 200 mesh sieves, by medicated powder weight, ethanol with 2-3 times of weight 50-90% extracted 1-2 hour in the backflow hermetic container earlier, filter out medicinal residues, obtain alcohol extract, add the water purification of 3-5 times of weight again by medicinal residues weight, boiled 1-2 hour with slow fire, leach medicinal residues and discard, obtain the water extract, merge alcohol extract and water extract, reclaim ethanol with the way of distillation, further concentrate, add again Mel and and white sugar, make buccal tablet.
6, a kind of treatment acute and chronic pharyngitis as claimed in claim 1, tonsillitic medicine production method, it is characterized in that: in proportion above-mentioned nine kinds of Chinese herbal medicine except Mel are cleaned, pulverize and cross 200 mesh sieves, by medicated powder weight, ethanol with 2-3 times of weight 50-90% extracted 1-2 hour in the backflow hermetic container earlier, filter out medicinal residues, obtain alcohol extract, add the water purification of 3-5 times of weight again by medicinal residues weight, boiled 1-2 hour with slow fire, leach medicinal residues and discard, obtain the water extract, merge alcohol extract and water extract, reclaim ethanol with the way of distillation, further concentrate, add Mel and filling material again, make pill.
CNB011283467A 2001-08-12 2001-08-12 Stomatopathy and throat disease treating health care medicine and its production process Expired - Fee Related CN1150927C (en)

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Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101020009B (en) * 2007-03-05 2010-05-19 广东南台药业有限公司 Medicated teafor clearing away heat of pharynx and larynx
CN101204422B (en) * 2007-12-12 2011-04-13 李亚萍 Chinese traditional medicine preparation for acute tonsillitis
CN101703553A (en) * 2009-11-24 2010-05-12 西南大学 Summer heat-clearing and toxin-resolving product for food and medicine purposes
CN101912112A (en) * 2010-07-23 2010-12-15 江苏老蚕坊蚕桑生物科技开发有限公司 Method for manufacturing compound mulberry leaf throat moistening and cleaning tablet
CN102641416A (en) * 2012-04-19 2012-08-22 王莲芬 Chinese patent medicine for treating toothache disease
CN105267471A (en) * 2014-07-19 2016-01-27 葛以东 Formula for treatment of acute or chronic tonsillitis
CN104958323A (en) * 2015-07-23 2015-10-07 耿佃敖 Ointment for treating sphagitis and preparation method of ointment
CN107854592A (en) * 2017-10-11 2018-03-30 烟台市口腔医院 A kind of preparation method for the film for treating oral ulcer that can quickly eliminate pain

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