CN1371271A - Cosmetic composition - Google Patents

Abstract

According to the present invention there is provided a cosmetic composition comprising: (a) at least one readily biodegradable quaternary ammonium agent; and (b) at least 5 %, by weight, of humectant. The compositions of the present invention give good skin care benefits, such as good moisturisation, good hydration, good skin feel, good skin softness and/or good skin smoothness, with low levels of negatives such as greasiness, stickiness or tack. In addition, such compositions are readily degraded once used and are consequently kinder to the environment.

Description

Cosmetic composition

Technical field

The present invention relates to cosmetic composition.The cosmetic composition of moist effect, hydration, dermal sensation, skin softness and/or the skin smoothness effect that can provide is provided particularly.

Background of invention

Skin is by the several layers cellularity, and these cells cover and protect keratin and the collagen fiber albumen that constitutes the skin texture skeleton.The outermost layer of these layers is called horny layer, and the known 25nm albumen bundle that is centered on by the thick layer of 8nm constitutes.The general penetrable cutin tunic of anion surfactant and organic solvent, and destroy the integrity of skin through degreasing (promptly removing the lipid material in the horny layer).Thisly will bring harsh feeling, thereby finally can make surfactant and solvent and keratin take place to interact and produce stimulation skin surface topology structural damage effect.Many people's skin all is exposed among this injury every day.And skin also can be subjected to other factors as being exposed to cold air or wind, mechanical friction, under water etc. and the injury that brings.Therefore, need a kind of mode that can improve or relax this injury.

Past has made such compositions, claims that they can help horny layer to keep its barrier and water retaining function in optimum performance, and needn't consider the deleterious interaction that skin may run in washing, work and amusement.For such compositions, wish that performance that they have is that they have good dermal sensation, water-retaining property, moisten effect (moisturisation), absorbability and/or friction and be coated with the feature into (rub-in).Prior art combinations is attempted by using one or more " skin beneficiating ingredient (skin benefit agent) " to bring these performances.For example, a kind of method of bringing height to moisten effect to skin is to introduce polyalcohols wetting agent material such as glycerol in compositions.But polyhydric alcohol content is high and therefore have the high skin composition that moistens effect and can be felt bad by consumer usually, because such compositions on being applied to skin the time, can being felt and be clamminess.

Seem to have direct relation between the consumption of skin protection beneficiating ingredient and compositions provides the effect from beneficial effect to skin.But in fact the content of skin beneficiating ingredient is high more, and the danger of associated detrimental effect is also just high more.Therefore, up to the present, need the relation between benefit that the high compositions of balance skin beneficiating ingredient content brings and the detrimental effect relevant with this high-load.Therefore, need relevant benefit such as dermal sensation, skin softness and the skin smoothness height that skin beneficiating ingredient content is high and therefore brought, but show relevant detrimental effect such as greasy, cohesiveness or the low compositions of sticky property.

Quaternary ammonium composition (quaternary ammonium agents) also known can be used in the cosmetic composition.For example referring to WO-A-99/27904, WO-A-96/32089 and EP-A-789,076.And US-A-5 discloses in 804,205 and it is said the skin care compositions that highly moistens effect and can not stay " adhesion " or " sticky " residue can be provided.Contain the nonirritating hydrophobic microsphere that quaternary ammonium compound (alkyl with 2 16-22 carbon atoms), wetting agent and mean diameter are lower than 50 μ m in these compositionss.It is said that hydrophobic polymerizing microballoons can obviously reduce and wetting agent content high relevant " cohesiveness ".But routine is used in quaternary ammonium composition of the prior art and is not easy to biodegradation usually, and therefore harmful to environment.

Be surprised to find that now comprising at least a compositions that is easy to the wetting agent of biodegradable quaternary ammonium composition and at least 5% weight has brought associated benefit such as dermal sensation, skin soft feeling and skin smoothness height, but shown that relevant detrimental effect such as greasy, cohesiveness or sticky property are low.

Although do not wish to be subjected to the restriction of any theory, believe that the quaternary ammonium composition among the present invention can form vesicle with wetting agent, and impel them to be deposited on the skin.Make thus and can smooth and equably wetting agent be applied on the skin, and thickness/adhesion/greasy minimum.Even when compositions comprises the wetting agent of high percentage composition, for example during the wetting agent of 30% weight, still has only lower common detrimental effect.And, believe that the quaternary ammonium composition helps to reduce the loss from the skin that emollient brings because of environmental factors such as water or friction.And, believe that the quaternary ammonium composition itself has brought skin effect, as good moist effect, good skin sense, good skin softness.

Summary of the invention

The invention provides cosmetic composition, comprising:

(a) at least aly be easy to biodegradable quaternary ammonium composition; With

(b) wetting agent of at least 5% weight.

Compositions of the present invention has been brought good skin care benefits, and as good skin moisturizing effect, good hydration, good dermal sensation, good skin softness and/or good skin flatness, detrimental effect such as greasy feeling, sticky sense or cohesiveness are low simultaneously.In addition, in case use, such compositions is easy to degraded, and therefore to the environment milder.

Detailed Description Of The Invention

Compositions of the present invention comprises at least a biodegradable quaternary ammonium composition and the wetting agent of being easy to.These compositions will describe in detail hereinafter.

Compositions of the present invention can be used in the purpose of any appropriate.Especially, compositions of the present invention is suitable for being applied topically on the skin.Particularly, these skin care compositions and methods can be forms such as cream frost, emulsion (lotion), gel.Preferred cosmetic composition of the present invention is the oil-in-water emulsion form at one or more oil phases of continuous aqueous phase, each oil phase contains single oily components or is the mixture of the oily components of miscible or homogenizing form, but described different oil phase contains material or these combinations of different materials that differs from one another.

Compositions of the present invention preferably comprises vesicle (vesicle).Preferred described vesicle comprises quaternary ammonium compound and wetting agent.Used in the present invention term " vesicle " be meant be arranged to seal, be generally the one or more bilayers in the spherical form, described bilayer comprises quaternary ammonium composition hereinafter described.

Preferably, compositions of the present invention comprises and is less than 10% (weight), preferably is less than 5% (weight), more preferably less than 3% (weight), the more preferably anion surfactant of 0% (weight).

Compositions of the present invention preferably is mixed with viscosity and is at least about 1,000mPa.s, preferably be about 1,000 to about 300,000mPa.s, be more preferably 2,500 to about 250,000mPa.s, particularly be about 5,000 to about 200, the product of (000mPa.s 26.8 ℃, net phase, Brookfield DV-II+ spindle CP52/CP41).The quaternary ammonium composition

Compositions of the present invention must comprise at least a biodegradable quaternary ammonium composition that is easy to.Be applicable to that any in the cosmetic composition is easy to biodegradable quaternary ammonium composition and all can be used for the present invention.The term that uses among the present invention " quaternary ammonium composition " is meant the chemical compound with quaternary nitrogen atoms or the mixture of chemical compound, and wherein quaternary nitrogen atoms replaces through one or more, preferred two parts that contain 6 or more carbon atoms.The term that uses among the present invention " is easy to biodegradation " and refers to 301 tests according to OECD, and at least 60% chemical compound is mineralising in 28 days.Be preferred for quaternary ammonium composition among the present invention and be selected from those with quaternary nitrogen atoms of being replaced by two parts, wherein each part comprises 10 or more a plurality of, preferred 12 or more a plurality of carbon atom.The quaternary ammonium composition that is particularly preferred among the present invention is selected from those that can form vesicle in polar solvent, and these can detect (the polarizing microscope method is used Nikon Eclipse E800 microscope, the amplification with * 60) by microscopic analysis.

Preferably, compositions of the present invention comprise at least 0.01%, more preferably at least 0.1%, also more preferably at least 1%, the further more preferably quaternary ammonium composition of at least 3% (weight).

Preferably, being used for quaternary ammonium composition of the present invention is selected from:

(a) general formula (I) or (II) shown in quaternary ammonium compound:

Each R wherein ₅The unit is independently from each other hydrogen, side chain or straight chain C ₁-C ₆The C of alkyl, side chain or straight chain ₁-C ₆Hydroxyalkyl and their mixture, preferably methyl and ethoxy; Each R ₆The unit is straight or branched C independently of one another ₁₁-C ₂₂Alkyl, straight or branched C ₁₁-C ₂₂Alkenyl and their mixture; X ^-Be can be compatible with the adjuvant composition with the skin care active composition anion; M is 1-4, is preferably 2; N is 1-4, is preferably 2, and Q is selected from following carbonyl unit:

R wherein ₇Be hydrogen, C ₁-C ₄Alkyl, C ₁-C ₄Hydroxyalkyl, and their mixture.

In the example of above-mentioned quaternary ammonium compound, unit-QR ₆Containing generally is the fatty acyl group unit of being derived and being obtained by the triglyceride source.The triglyceride source is preferably derived from Adeps Bovis seu Bubali, partially hydrogenated Adeps Bovis seu Bubali, Adeps Sus domestica, partially hydrogenated Adeps Sus domestica, vegetable oil and/or partially hydrogenated vegetable oil, as low erucic acid rapeseed oil, safflower oil, Oleum Arachidis hypogaeae semen, rapeseed oil, sunflower oil, Semen Maydis oil, soybean oil, tall oil (tall oil), Testa oryzae wet goods, and these oily mixture.

Counter ion counterionsl gegenions X in the above-claimed cpd ^-Can be any compatible anion, the anion of strong acid preferably, for example chloride ion, bromide ion, methylsulfate, ethyl sulphate, sulfate radical, nitrate anion etc. are more preferably chloride ion or methylsulfate.Anion also can but less double charge, the X in this case of preferably having ^-Represent group half.

The preferred quaternary ammonium compound of the present invention is diester and/or diamides quaternary ammonium (DEQA) chemical compound, and diester and diamides have general formula (II), and wherein carbonyl Q is selected from:

Adeps Bovis seu Bubali, low erucic acid rapeseed oil and Petiolus Trachycarpi oil are convenient and the economic unitary source of fatty acyl group, are suitable in the present invention as R ₆The unit.

Counter ion counterionsl gegenions X ^-Can be chloride ion, bromide ion, methylsulfate, formate, sulfate radical, nitrate anion and their mixture.In fact, anion X ^-Only the counter ion counterionsl gegenions as positively charged quaternary ammonium compound exist.Do not consider within the scope of the invention it is defined as any specific anion.

In the present invention, when regulation adopts diester, wherein will comprise common existence by monoesters that brings in the preparation process and three esters.

(b) general formula (III) or (IV) shown in quaternary ammonium compound:

R wherein ₉Be no cyclic aliphatic C ₁₅-C ₂₁Alkyl, R ₁₀Be C ₁-C ₆Alkyl or alkylidene.

These pKa values are no more than about 4 ammonium compounds, when disperseing in aqueous solution, can produce positive charge on the spot, and condition is that the pH of final composition is no more than about 6.

(c) logical formula V or (VI) shown in quaternary ammonium compound:

R wherein ₉And R ₁₀As hereinbefore defined, R ₁₁Be selected from C ₁-C ₄Alkyl and hydroxyalkyl.

Counter ion counterionsl gegenions X ^-Can be chloride ion, bromide ion, methylsulfate, formate, sulfate radical, nitrate anion and their mixture.In fact, anion X ^-Only the counter ion counterionsl gegenions as positively charged quaternary ammonium compound exist.Do not consider within the scope of the present invention it is defined as any specific anion.

(d) general formula (VII) or (VIII) shown in quaternary ammonium compound:

Wherein, n is 1-6, R ₉Be selected from no cyclic aliphatic C ₁₅-C ₂₁Alkyl, R ₁₂Be selected from C ₁-C ₄Alkyl and hydroxyalkyl.

These pKa values are no more than about 4 ammonium compounds, when disperseing in aqueous solution, can produce cationic charge on the spot, and condition is that the pH of final composition is no more than about 6.

Counter ion counterionsl gegenions X ^-Can be chloride ion, bromide ion, methylsulfate, formate, sulfate radical, nitrate anion and their mixture.In fact, anion X ^-Only the counter ion counterionsl gegenions as positively charged quaternary ammonium compound exist.Do not plan in the scope of the invention it is defined as any specific anion.

(e) general formula (IX) or (X) shown in quaternary ammonium compound:

R wherein ₅, R ₆, Q, n and X ^-As above-mentioned general formula (I) with the definition (II), R ₁₃Be selected from C ₁-C ₆Alkylidene, preferably ethylidene.

(f) mixture of above-mentioned quaternary ammonium compound.

The preferred quaternary ammonium composition that is used for the present invention be above-mentioned (b) part described in those.Particularly, preferably above diester shown in the general formula (II) and/or diamides quaternary ammonium (DEQA) chemical compound.The preferred diester that is used for the present invention is R in the chemical compound shown in the general formula (II) ₅, R ₆And X ^-As hereinbefore defined and Q be those that are shown below:

The preferred diamides that is used for the present invention is R in the chemical compound shown in the general formula (II) ₅, R ₆And X ^-As hereinbefore defined and Q be those that are shown below:

The example that is suitable for being used in the preferred quaternary ammonium compound in the present composition is: N; N-two (canola acyl group-oxygen-ethyl)-N; N-alkyl dimethyl ammonium chloride, N; N-two (canola acyl group-oxygen-ethyl)-N-methyl; N-(2-ethoxy) methylsulfuric acid ammonium, N; N-two (canola acyl group-oxygen-ethyl)-N-methyl, N-(2-ethoxy) ammonium chloride and their mixture.Being particularly preferred among the present invention is N, N-two (canola acyl group-oxygen-ethyl)-N-methyl, N-(2-ethoxy) methylsulfuric acid ammonium.

Although preferably derived from the quaternary ammonium compound of " canola acyl group (canolyl) " fatty acyl group; but the example of the quaternary ammonium compound that other is suitable for derived from " canola acyl group " in the above-mentioned example wherein by following displaced fatty acyl group: " Adeps Bovis seu Bubali acyl group, cocoyl, palmityl (palmyl), lauroyl, oleoyl, Oleum Ricini acyl group, stearyl, palmityl (palmityl) " substitutes, and these obtain the unitary triglyceride of fatty acyl group source corresponding to deriving.These alternative fatty acyl group sources can comprise saturated entirely, perhaps preferably to the undersaturated chain of small part.Wetting agent

Second kind of fundamental of the present composition is its wetting agent that comprises at least 5% weight.The present invention plant use term " wetting agent (humectant) ' be meant the material that can bring the benefit that keeps water to skin.Preferably, the present composition comprises at least 7.5% (weight), more preferably at least 10% (weight), more preferably at least 15% (weight) also, the further preferred wetting agent of at least 30% (weight).

Any wetting agent of cosmetic composition that is applicable to all can be used for the present invention.The non-limiting example that is used for suitable wetting agent of the present invention is disclosed in WO 98/22085, WO 98/18444 and WO97/01326.Be preferred for wetting agent of the present invention and be selected from, but be not limited to: aminoacid and derivant thereof such as proline and arginine aspartate, 1; the 3-butanediol, propylene glycol and water and Korean pine platymiscium (codium tomentosum) extract, collagen amino acid or peptide; creatinine, diglycerol, biological polyoses glue-1 (biosaccharide gum-1); glucosamine salt, glucuronate, glutamate, Glu; the polyglycol ether of glycerol (for example glycerin polyoxyethylene ether 20); glycerol, glycerol list propoxylate, glycogen; hexanediol; Mel, with and extract or derivant, hydrogenated starch hydrolysates; the hydrolysis mucopolysaccharide; inositol, keratin aminoacid, urea; LAREX A-200 (deriving from Larex); glycosaminoglycans, methoxyl group PEG-10, methyl gluceth-10 and-20 (all can be available from Amerchol; be positioned at Edison; NJ), methyl glucoside, 3-methyl isophthalic acid; the 3-butanediol; N-acetyl glucosamine salt, (as PEG 15 butanediols, PEG 4 for Polyethylene Glycol and derivant thereof; PEG 5 tetramethylolmethanes; PEG 6, and PEG 8, and PEG 9); tetramethylolmethane; 1,2-pentanediol, PPG-1 glycerin ether; PPG-9; 2-Pyrrolidone-5-carboxylic acid and salt thereof such as glyceryl PCA, sugared isomerate, SEACARE (deriving from Secma); sericin; Silk Amino Acids, acetyl group hyaluronate sodium, hyaluronate sodium; poly (sodium aspartate); polyglutamic acid sodium, sorbitol polyoxyethylene ether (sorbeth) 20, sorbitol polyoxyethylene ether 6; sugar and sugar alcohol and derivant such as glucose; mannose and polyglycereol sorbitol, trehalose, triglycerin; trimethylolpropane; three (methylol) aminomethane salt, yeast extract, and their mixture.

More preferably, be used for wetting agent of the present invention and be selected from: glycerol, urea, butanediol, Polyethylene Glycol and derivant thereof, and their mixture.Also more preferably, being used for wetting agent of the present invention is selected from: glycerol, urea and their mixture, particularly glycerol.Optional member

Compositions of the present invention can comprise various optional components, and these optional members are suitable for making compositions of the present invention to have more pleasant beauty treatment or beautify characteristic, have perhaps brought additional use benefit to compositions.These optional members commonly used are that those of ordinary skills are known.Comprising various used for cosmetic compositions, as at " (international cosmetics dictionary of CTFA and handbook (CTFA InternationalCosmetic Ingredient Dictionary and Handbook, the 7th edition, Wenninger and McEwen compile, (The Cosmetic, Toiletry, and Fragrance Association, Inc., Washington, those that can find D.C., 1997)).Below listed some non-limiting example in these optional members.Emollient

Particularly preferred optional member is emollient (emollient) in the present composition.Slickness and flexibility that emollient is used for lubricated skin, promotes skin, prevention and alleviate xerosis cutis, and/or protection skin.Various suitable emollients are known and can be with in the present invention.The Cosmetics that Sagarin showed has comprised numerous examples that are suitable for use as the material of emollient among the Science and Technology (the 2nd edition, the 1st volume, 32-43 page or leaf (1972)).Preferably, compositions of the present invention comprises greater than 1% (weight), more preferably is at least 5% (weight), also more preferably is at least the emollient of 10% (weight).

Being preferred for emollient of the present invention is selected from:

I) have and contain 7 straight or branched hydrocarbon approximately, as dodecane, squalane, vaseline, cholesterol and their derivant, Parleam, 2-Methylpentadecane and C to about 40 carbon atoms ₇-C ₄₀Isoparaffin (is C ₇-C ₄₀Branched-chain hydrocarbons).

Ii) C ₁-C ₃₀Carboxylic acid and C ₂-C ₃₀The C of dicarboxylic acids ₁-C ₃₀Alcohol ester, for example isononyl isononanoate, isopropyl myristate, propanoic acid myristin, isopropyl stearate, behenic acid docosane ester, di-2-ethylhexyl maleate, diisopropyl adipate and dilinoleic acid diisopropyl ester.

Iii) C ₁-C ₃₀The monoglyceride of carboxylic acid, two glyceride and triglyceride and ethoxylated derivative thereof.The polyethyleneglycol derivative of the glyceride that is suitable for comprises: PEG-20 Semen Armeniacae Amarum glyceride, PEG-60 Semen Armeniacae Amarum glyceride, PEG-11 American Avocado Tree glyceride, PEG-6 suffering/caprin, PEG-8 suffering/caprin, PEG-20 corn glyceride, PEG-60 corn glyceride, PEG-60 Radix Oenotherae erythrosepalae oil glyceride, PEG-7 glyceryl cocos nucifera oil ester, PEG-30 glyceryl cocos nucifera oil ester, PEG-40 glyceryl cocos nucifera oil ester, PEG-78 glyceryl cocos nucifera oil ester, PEG-80 glyceryl cocos nucifera oil ester, PEG-12 glyceryl dioleate, PEG-15 glyceryl isostearate, PEG-20 glyceryl isostearate, PEG-30 glyceryl isostearate, PEG-75 cocoa butter glyceride, PEG-20 hydrogenated palm oil glyceride, PEG-70 Fructus Mangifera Indicae glyceride, PEG-13 ermine YOUGAN grease, PEG-75 sal tree fat glyceride, PEG 10 olive oil glyceride, PEG-12 palm-kernel oil glyceride, PEG-45 palm-kernel oil glyceride, PEG-8 glyceryl laurate and PEG-30 glyceryl laurate.The mixture of the polyethyleneglycol derivative of glyceride also can be used for the present invention.

Iv) C ₁-C ₃₀The alkylidene diol ester of carboxylic acid, for example C ₁-C ₃₀The ethylene glycol ester of carboxylic acid and diester, and propylene glycol monoester and diester, for example diglycol stearate.

V) organopolysiloxane oil.Organopolysiloxane oil can be mixture volatile, nonvolatile or volatility and non-volatile polysiloxanes.Term used herein " nonvolatile " is meant and is liquid under environmental condition, and flash-point (under 1 atmospheric pressure) is more than or equal to those about 100 ℃ polysiloxanes.Term used herein " volatile " is meant all other polysiloxane oil.The organopolysiloxane oil that is suitable for can be selected from the various polysiloxanes of volatility and viscosity leap relative broad range.Preferred non-volatile polysiloxanes.The polysiloxanes that is suitable for is disclosed in United States Patent (USP) 5,069,897 (December was authorized on the 3rd in 1991).Be preferred for organopolysiloxane of the present invention and be selected from polydimethylsiloxane that poly-alkylsiloxane, alkyl replace, dimethiconol, polyoxyethylene alkyl aryl radical siloxane and composition thereof.More preferably being used for of the present invention is poly-alkylsiloxane and ring-type polymethyl siloxane (cyclomethicone).Polydimethylsiloxane preferably in the poly-alkylsiloxane.

Vi) vegetable oil and hydrogenated vegetable oil.The example of vegetable oil and hydrogenated vegetable oil comprises: the partial hydrogenation of the oil in safflower oil, Oleum Ricini, Oleum Cocois, Oleum Gossypii semen, pilchardine, palm-kernel oil, Petiolus Trachycarpi oil, Oleum Arachidis hypogaeae semen, soybean oil, rapeseed oil, Semen Lini oil, Testa oryzae oil, Oleum Pini, Oleum sesami, sunflower oil, above-mentioned source and perhydrogenate form, and their mixture.

Vii) animal oil, for example cod liver oil, lanoline and derivant thereof are as acetylated lanolin and lanolin fatty acid isopropyl ester.Preferred lanolin oil.

The viii) operable C that also has polypropylene glycol ₄-C ₂₀The C of alkyl ether, polypropylene glycol ₁-C ₂₀Carboxylate and two-C ₈-C ₃₀Alkyl ether, example comprise PPG-14 butyl ether, PPG-15 stearyl ether, dicaprylyl ether, dodecyl Octyl Ether and composition thereof.

Ix) polyol carboxylic acid ester.

X) mixture of mentioned component.

The emollient that is preferred among the present invention is selected from: dodecane, squalane, cholesterol and derivant thereof, 2-Methylpentadecane, isononyl isononanoate, vaseline, lanoline and derivant thereof, safflower oil, Oleum Ricini, Oleum Cocois, Oleum Gossypii semen, palm-kernel oil, Petiolus Trachycarpi oil, Oleum Arachidis hypogaeae semen, soybean oil, polyol carboxylic acid ester and their mixture.More preferably be used for emollient of the present invention and be selected from polyol carboxylic acid ester, vaseline and their mixture.

These esters are derived from sugar or polyol moiety and one or more carboxylic moiety.Depend on the sour and sugared of formation, these esters can be the liquid or solid form at ambient temperature.The example of liquid ester comprises: four oleic acid glucose esters, glucose four esters of soya fatty acid (unsaturated), mannose four esters of mixed soya fatty acid, oleic galactose four esters, linoleic arabinose four esters, xylose four linoleates, five oleic acid gala sugar esters, four oleic acid sorbitol esters, sorbitol six esters of unsaturated soya fatty acid, the five oleic acid esters of xylitol, four oleic acid sucrose ester, five oleic acid sucrose ester, six oleic acid sucrose ester, seven oleic acid sucrose ester, eight oleic acid sucrose ester and composition thereof.The example of solid ester comprises: sorbitol six esters, carboxylate moiety wherein are that mol ratio is 1: 2 palm acid ester and an Arachidate; The octaester of Raffinose, carboxylate moiety wherein are that mol ratio is 1: 3 linoleate and a docosane acid esters; Seven esters of maltose, wherein esterification carboxylic moiety are that mol ratio is 3: 4 Oleum Helianthi fatty acid and a lignocerane acid esters; The octaester of sucrose, wherein esterification carboxylic moiety are that mol ratio is 2: 6 oleate and a docosane acid esters; And the octaester of sucrose, wherein esterification carboxylic moiety is that mol ratio is 1: 3: 4 laurate, linoleate and a docosane acid esters.Preferred solid matter is an Olestra, and wherein esterification degree is 7-8, and fatty acid part wherein is C ₁₈Single-and/or two-unsaturated acids and behenic acid, wherein the mol ratio of unsaturated acids and behenic acid is 1: 7-3: 5.Particularly preferred sugar cube polyester is the octaester of sucrose, wherein contains 7 22 carbon fatty acid parts and about 1 oleic acid part in the molecule approximately.Other comprises Oleum Gossypii semen or soya fatty acid sucrose ester.These Esters also are disclosed in United States Patent (USP) 2,831,854; United States Patent (USP) 4,005,196 (Jandacek, on January 25th, 1977 authorized); United States Patent (USP) 4,005,195 (Jandacek, on January 25th, 1977 authorized), United States Patent (USP) 5,306,516 people such as (, on April 26th, 1994 authorized) Letton; United States Patent (USP) 5,306,515 (people such as Letton, on April 26th, 1994 authorized); United States Patent (USP) 5,305,514 (people such as Letton, on April 26th, 1994 authorized); United States Patent (USP) 4,797,300 (people such as Jandacek, on January 10th, 1989 authorized); United States Patent (USP) 3,963,699 (people such as Rizzi, on June 15th, 1976 authorized); United States Patent (USP) 4,518,772 (Volpenhein, on May 21st, 1985 authorized); And United States Patent (USP) 4,517,360 (Volpenhein, on May 21st, 1985 authorized).

Be applicable to that the polynary ester of polyol fatty acid of the present invention can be prepared by the whole bag of tricks known in the art.These methods comprise that the various catalyst of employing carry out ester exchange by polyhydric alcohol and methyl, ethyl or glycerin fatty acid ester; Adopt fat acyl chloride that polyhydric alcohol is carried out acylation; Adopt fatty acid anhydride that polyhydric alcohol is carried out acylation; And known employing fatty acid carries out acylation to polyhydric alcohol.For example can be referring to United States Patent (USP) 2,831,854; United States Patent (USP) 4,005, the content described in 196 (Jandacek, on January 25th, 1977 authorized).

Particularly preferred material is the material of the poly-oleic acid sucrose ester of INCI called after.Other skin beneficiating ingredient

Can adopt other skin beneficiating ingredient in the present composition.The example that can be used for other skin beneficiating ingredient of the present composition comprises:

(a) element-vitamine compound

Can contain element-vitamine compound, its precursor and derivant thereof in the present composition.These element-vitamine compounds can be native forms, also can be synthesized forms.The element-vitamine compound that is suitable for comprises: vitamin A (for example, beta-carotene, tretinoin, retinol, retinal analog derivative (retinoids), retinyl palmitate, propanoic acid retinol ester etc.), vitamin B (for example, nicotinic acid, nicotiamide, riboflavin, pantothenic acid etc.), vitamin C (for example, ascorbic acid etc.), vitamin D (for example, ergosterol, ergocalciferol, cholecalciferol etc.), vitamin E (for example, tocopherol acetate etc.) and vitamin K (for example, phytonadione, menadione, phthiocol etc.) chemical compound.The element-vitamine compound that is preferred in the present composition is a vitamin B ₃Chemical compound.Vitamin B ₃Chemical compound is specially adapted to regulate skin, and related content is disclosed among the WO-A-97/39733.If the use element-vitamine compound then preferably comprises about 0.01% (weight) to about 50% (weight) in the present composition, more preferably from about 0.1% (weight) also is more preferably the vitamin B of 0.5% (weight) to about 5% (weight) to about 10% (weight) ₃Chemical compound.

Be used for term " vitamin B of the present invention ₃Chemical compound " be meant chemical compound with following formula:

Wherein R is-CONH ₂(being nicotiamide) ,-COOH (being nicotinic acid) or-CH ₂OH (being cigarette base alcohol (nicotinyl alcohol)); Its derivant; And the salt of above-claimed cpd.

Said vitamin B ₃The example of the derivant of chemical compound comprises: nicotinate comprises the non-distensibility of blood vessel ester of nicotinic acid; Cigarette base alcohol ester, nicotinic acid N-oxide and the nicotinoyl amine n-oxide of cigarette base aminoacid, carboxylic acid.

Suitable vitamins B ₃Examples for compounds is well known in the art, and can buy from a plurality of sources, for example the Sigma chemical company (St.Louis, MO); ICN Biomedicines, Inc. (Irvin, CA) and the Aldrich chemical company (Milwaukee, WI).

Element-vitamine compound can be substantially adds with the form of pure product, or adds to separate the form that obtains extract by natural origin (for example plant) through suitable physics and/or chemical method.

(b) crease-resistant and anti-atrophoderma active component

Can be used for crease-resistant (anti-winkle) in the present composition and the example of anti-atrophoderma (anti-skinatrophy) active component includes, but are not limited to: lactic acid and derivant thereof; Tretinoin and derivant thereof (for example cis with trans); Retinol; Retinyl ester; Nicotiamide; Salicylic acid and derivant thereof; The D of sulfur-bearing and L aminoacid and derivant and salt, particularly N-acetyl derivative, wherein preferred examples is N-acetyl group-L-cysteine; Thio-alcohol, for example, ethyl mercaptan; Hydroxy acid; Phytic acid; Thioctic acid; Lysophosphatidic acid, and decorticating agent (skin peel agent) (for example, phenols etc.).

(c) antimicrobial and antifungal activity composition

Can be used for the antimicrobial of the present composition and the example of antifungal activity composition comprises: Beta-lactam medicine, quinolones, ciprofloxacin, norfloxacin, tetracycline, erythromycin, amikacin, 2,4,4 '-three chloro-2 '-hydroxy diphenyl ether, 3,4,4 '-three chloro-carbanilides, phenyl phenol, phenoxypropanol, the phenoxy group isopropyl alcohol, doxycycline, capreomycin, chlohexidine, chlortetracycline, oxytetracycline, clindamycin, ethambutol, esomedina, metronidazole, penta oxygen benzene carbon amidine, gentamycin, kanamycin, lincomycin (lineomycin), methacycline, hexamethylenamine, minocycline (minocycline), neomycin, netilmicin, paromomycin, streptomycin, tobramycin, miconazole, quadracycline, erythromycin, erythromycin zinc, erythromycin propionate lauryl sulfate, erythromycin stearate, amikacin sulfate, doxycycline hydrochloride, capreomycin sulfate Capastat sulfate, chlorhexidine gluconate, chlorhexidine dihydrochloride, chlortetracycline hydrochloride, tetramycin hydrochloride, clindamycin hydrochloride, ebutol, the hydrochloric acid metronidazole, hydrochloric acid penta oxygen benzene carbon amidine, gentamycin sulfate, kanamycin sulfate, lincomycin hydrochloride (lineomycin), methacycline hydrochloride, methenamine hippu, mandelamine, minocycline hydrochloride, polygynax, netilmicin sulfate, paromomycin sulfate, streptomycin sulfate, tobramycin sulfate, the hydrochloric acid miconazole, amantadine hydrochloride (amanfadine hydrochloride), PK-Merz (Merz) (amanfadine sulfate), Octopirox, chlorxylone, nystatin, tolnaftate (tolnaftate), pyrithione zinc and clotrimazole.

(d) sunscreen actives composition

Can also comprise the sunscreen actives composition in the compositions of the present invention.Various sunscreen are all in the present invention available.These sunscreen include organic compounds and salt and inorganic particulate material.Although without wishing to be bound by theory, believe that sunscreen can prevent to be subjected to ultraviolet radiation by one or more following mechanism protection skins, comprising: absorption, scattering and reflect UV radiation.The non-limiting example of these sunscreen is disclosed in: United States Patent (USP) 5,087,445 (people such as Haffey, on February 11st, 1992 authorized); United States Patent (USP) 5,073,372 (people such as Turner, December was authorized on the 17th in 1991); United States Patent (USP) 5,073,371 (people such as Turner, December was authorized on the 17th in 1991); United States Patent (USP) 5,160,731 (people such as Sabatelli, on November 3rd, 1992 authorized); United States Patent (USP) 5,138,089 (Sabatelli, on August 11st, 1992 authorized); United States Patent (USP) 5,041,282 (Sabatelli, on August 20th, 1991 authorized); United States Patent (USP) 4,999,186 (people such as Sabatelli, on March 12nd, 1991 authorized); United States Patent (USP) 4,937,370 (Sabatelli, authorize June 26 nineteen ninety); And people such as Segarin is in the described content of " cosmetic science and technology " (Cosmetics Science and Technology, the VIII chapter is below 189 pages).Wherein, preferred sunscreen is selected from: p-methoxycinnamic acid 2-Octyl Nitrite; ethylhexyl salicylate; octocrylene; the hydroxyl methoxy benzophenone; N; N-dimethylaminobenzoic acid 2-Octyl Nitrite; para-amino benzoic acid; 2-phenyl-benzimidazole-5-sulfonic acid; salicylic acid ester in the high Meng; the p-methoxycinnamic acid diethanolamine; 4; 4 '-methoxyl group-tert-butyl group dibenzoyl methane; 4-isopropyl diphenyl formyl methane; 3-(4-methyl benzal) Camphora; the 3-benzylidene camphor; 4-N; N-dimethylaminobenzoic acid and 2; the ester of 4-dihydroxy benzophenone; 4-N; the ester of N-dimethylaminobenzoic acid and 2-hydroxyl-4-(2-hydroxyl-oxethyl) benzophenone; 4-N; the ester of N-dimethylaminobenzoic acid and 4-hydroxy benzophenone acyl group methane; 4-N; the ester of N-dimethylaminobenzoic acid and 4-(2-hydroxyl-oxethyl) dibenzoyl methane; 4-N; N-two (2-ethylhexyl)-amino benzoic Acid and 2; the ester of 4-dihydroxy benzophenone; 4-N; the ester of N-two (2-ethylhexyl) amino benzoic Acid and 2-hydroxyl-4-(2-hydroxyl-oxethyl) benzophenone; 4-N; the ester of N-two (2-ethylhexyl) amino benzoic Acid and 4-hydroxy benzophenone acyl group methane; 4-N; the ester of N-two (2-ethylhexyl) amino benzoic Acid and 4-(2-hydroxyl-oxethyl) dibenzoyl methane; 4-N; N-(2-ethylhexyl) methylamino benzoic acid and 2; the ester of 4-dihydroxy benzophenone; 4-N; the ester of N-(2-ethylhexyl) methylamino benzoic acid and 2-hydroxyl-4-(2-hydroxyl-oxethyl) benzophenone; 4-N; the ester of N-(2-ethylhexyl) methylamino benzoic acid and 4-hydroxy benzophenone acyl group methane; 4-N, the ester of N-(2-ethylhexyl) methylamino benzoic acid and 4-(2-hydroxyl-oxethyl) dibenzoyl methane; titanium dioxide; zinc oxide; ferrum oxide and composition thereof.

The sunscreen that more preferably is used for the present composition is selected from: N; N-dimethyl-para-amino benzoic acid 2-Octyl Nitrite; p-methoxycinnamic acid 2-Octyl Nitrite; octocrylene; ethylhexyl salicylate; salicylic acid ester in the high Meng; para-amino benzoic acid; the hydroxyl methoxy benzophenone; 2-Phenylbenzimidazole-5-sulfonic acid; the p-methoxycinnamic acid diethanolamine; 4; 4 '-methoxyl group-tert-butyl group dibenzoyl methane; 4-isopropyl diphenyl formoxyl methane; 3-(4-methyl benzal) Camphora; the 3-benzylidene camphor; 4-N, the ester of N-(2-ethylhexyl) methylamino benzoic acid and 4-(2-hydroxyl-oxethyl) dibenzoyl methane; titanium dioxide; zinc oxide; ferrum oxide and composition thereof.

The definite consumption of the sunscreen that can use depends on selected sunscreen and the sun protection factor that will reach, and (Sun Protection Factor SPF) is worth and different.SPF is normally used, is used to weigh the photoprotection that sunscreen prevents to produce skin erythema.Referring to Federal Register, 43 volumes, No. 166,38206-38269 page or leaf, on August 25th, 1978.Thickening agent

The present composition preferably contains thickening agent.The various thickening agents that are applicable to cosmetic composition all can be used for the present invention.Preferred thickening is selected from non-ionic water-soluble polymer, aliphatic alcohol and composition thereof.The non-ionic polymers that is suitable for comprises such water-soluble polymer, as cellulose ether (for example hydroxy butyl methyl cellulose, hydroxypropyl cellulose, hydroxypropyl emthylcellulose, ethylhydroxyethylcellulose, hydrophobically modified hydroxyethyl-cellulose and hydroxyethyl-cellulose), poly-(oxygen ethylene), polyvinyl alcohol, polyvinyl pyrrolidone, hydroxypropyl guar gum, amylose (amulose), ethoxy amylose (amylose), starch and starch derivatives.The aliphatic alcohol that is suitable for is higher molecular weight, the nonvolatile primary alconol with following general formula:

RCH ₂OH

Wherein R is C _8-20Alkyl.They can be made by natural oil or fat, by with fatty acid-the COOH carboxyl reduction becomes the hydroxyl-functional base to obtain.The aliphatic alcohol that perhaps, can prepare identical or similar structures by conventional method known in the art.Suitable aliphatic alcohol comprises: tadenan, C ₉-C ₁₁Alcohol, C ₁₂-C ₁₃Alcohol, C ₁₂-C ₁₅Alcohol, C ₁₂-C ₁₄Alcohol, C ₁₄-C ₁₅Alcohol, capryl alcohol, spermaceti/stearyl alcohol, cocoanut oil alcohol, decanol, different spermol, isooctadecanol, lauryl alcohol, oleyl alcohol, palm kernel alcohol, stearyl alcohol, spermol, tallow alcohol, tridecyl alcohol or myristyl alcohol, but be not to be only limited to these.Polar solvent

Can also comprise polar solvent in the compositions of the present invention.Any polar solvent that is suitable for being used in the cosmetic composition all can be with in the present invention.But this polar solvent must have enough polarity to impel the vesicle that forms among the present invention.The polar solvent that is preferred in the present composition is a water.

Preferably contain 10%-90% in the compositions of the present invention, 20%-80% more preferably, the also polar solvent of 30%-60% (weight) more preferably.Other optional member

Can contain various other optional components in the present composition.These annexing ingredients should be pharmaceutically useful.By functional classification, be applicable to that the non-limiting example of the composition in the present composition comprises: grinding agent, absorbent, anti-acne active ingredient, anticaking agent, dandruff removing agent, antiperspirant, antioxidant, the antiviral activity composition, artificial suntan and promoter, bio-additive, bleach, bleach-activating, brightening agent, synergist, buffer agent, chelating agen, chemical addition agent, coloring agent, the beauty treatment composition, cleaning agent, the used for cosmetic astringent, the used for cosmetic antibacterial, modifier, deodorizer, the decortication active component, depilatory, medicinal astringent, dyestuff, transfection agents, enzyme, the external application analgesic agent, foaming agent, correctives, film former, perfume composition, anthelmintic, antifungus agent, on-steroidal anti-inflammatory activity composition, opacifier, oxidation dye, oxidant, the deinsectization composition, pH regulator agent such as citric acid, the pH buffer agent, active constituents of medicine, plasticizer, antiseptic, free radical scavenger, skin or hair or fingernail bleach, skin or hair or fingernail conditioner, skin or hair or fingernail penetration enhancer, stabilizing agent, surfactant, surface amendment, Reducing agent, the temperature inhibitor, viscosity modifier and heating agent are as the heating zeolite.Also can be used for of the present invention is to beautify component (aesthetic components) as coloring agent, essential oil, skin healing agent.Other optional material that is applicable to this comprises: pigment.The pigment that is applicable to the present composition can be organic and/or inorganic constituents.In term pigment scope, also comprise less colored or the low gloss material, as the delustring finishing agent, and light scattering agent.The example of the pigment that is suitable for has ferrum oxide, acyl glutamic acid ferrum oxide, titanium dioxide, ultramarine, D﹠amp; C dyestuff, alkermes and composition thereof.Compound method

Preferred compositions of the present invention prepares in the mode that quaternary ammonium compound can form vesicle.Also contain wetting agent in the preferred described vesicle.Preferably, also comprise emollient in the described vesicle.For guaranteeing the optimum performance characteristic, the preferred present composition is prepared by following steps:

(i) under the temperature that is higher than the quaternary ammonium congruent melting point with all or part of quaternary ammonium composition and wetting agent, water solublity skin care activity composition (if comprising), preferably also have polar solvent to mix mutually;

(ii) randomly, this mixture of vigorous stirring;

(iii) in another independent container, prepare Emulsion as follows: be higher than under the temperature of quaternary ammonium compound fusing point and mix with containing the oil phase of emollient, relevant thickening agent (is under the oil-soluble situation at described thickening agent) and remaining quaternary ammonium composition.Prepare water separately.Water, relevant thickening agent (is under the water miscible situation at described thickening agent) are heated to the temperature identical with oil phase with other water soluble ingredient.

(iv), under stirring condition, water is combined with oil phase then the temperature of the oil phase of Emulsion and water balance roughly.

(v) when preparation Emulsion, the mixture of making in the step (i) is under agitation added in the above-mentioned Emulsion.Using method

Cosmetic composition of the present invention can nursing skin usual manner use.With the compositions of effective dose, be generally about 0.1 gram to about 50 grams, preferred about 1 gram to about 20 grams are applied to wet or do, on the preferred wet skin.The application of compositions generally includes compositions rubbed on skin and smears, and normally carries out with hands and finger.Then compositions is stayed on the skin, perhaps, preferably rinsed from skin.

Therefore, the preferable methods of nursing skin comprises the following steps:

(a) cosmetic composition with effective dose is applied on the skin,

(b) rinsing skin.

Preferred aspect of the present invention relates to said method, be included in be applied to compositions on the moist skin before, compositions is applied on the dry skin.Therefore, preferable methods comprises

(i) cosmetic composition with effective dose is applied on the dry skin;

(ii) at the following rinsing skin of shower (shower);

(iii) reuse described compositions; And

(iv) rinsing once more.

Most damages to human body skin be by skin in cleaning process repeat repeatedly to be exposed to the compositions that contains surfactant in and produce.Have now found that can the application of the invention compositions alleviate this damage.Therefore another method for optimizing comprises:

(i) adopt the compositions that contains surfactant to clean skin;

(ii) rinsing skin;

(iii) compositions of the present invention is used for moist skin;

(iv) rinsing skin.

Now also find compositions of the present invention when introducing the part of the conventional cleaning procedure of conduct, particularly suitable.Therefore another method for optimizing comprises:

(i) application comprises following compositions on skin:

(a) at least a quaternary ammonium compound;

(b) wetting agent; With

(ii) rinsing skin;

(iii) repeating step (i) and (ii) in 48 hours.

Compositions of the present invention can also be used for alleviating because of skin be exposed to damage that ultraviolet radiation causes, in swimming or similarly contact the damage that causes in the water exercise with water or contact the skin injury that causes during in bathing with water.

Embodiment

Following examples are used to further specify the embodiment preferred in the scope of the invention.The embodiment that provides only is used for illustrative purposes, rather than limitation of the invention, because can carry out multiple variation to the present invention under the situation that does not deviate from the spirit or scope of the present invention.Unless otherwise indicated, all the components is all with the weight percent meter of active component.

Embodiment	??1	??2	??3	??4	??5	??6	??7	??8	??9	??10	??11	??12	??13
																% (weight)
Quaternary ammonium composition (seeing note)	??3	??3	??3	??3	??3	??3	??3	??3	??3	??3	??3	??3	??3	??A
															Glycerol	??32	??32	??32	??32	??32	??32	??32	??-	??-	??-	??-	??-	??-	??A
Urea	??-	??-	??-	??-	??-	??-	??-	??22	??22	??22	??22	??22	??22	??A
															Vaseline	??-	??-	??10	??-	??12	??15	??-	??-	??-	??10	??-	??12	??15	??B
Lanoline 1	??-	??-	??-	??7.5	??5	??-	??15	??-	??-	???-	??10	??10	??-	??B
															The Coronet lanoline 1	??-	??-	??-	??-	??-	??-	??5	??-	??-	???-	??-	??-	??-	??B
Super sterol ester 1	??-	??-	??-	??-	??-	??-	??5	??-	??-	???-	??-	??-	??-	??B
															Sefa cotton oil acid esters	??21	??21	??12	??12	??-	??-	??-	??21	??21	??12	??12	??-	??-	??B
Polydimethylsiloxane 10 centistokes	??-	??0.5	??0.5	??0.5	??-	??0.5	??0.5	??0.5	??-	???-	??-	??0.5	??0.5	??B
															Polydimethylsiloxane 1000 centistokes	??-	??1.0	??1.0	??1.0	??-	??1.0	??1.0	??1.0	??-	???-	??-	??1.0	??1.0	??B
The ring-type polymethyl siloxane	??-	??2.5	??2.5	??2.5	??-	??2.5	??2.5	??2.5	??-	???-	??-	??2.5	??2.5	??B
															Florasun?PEG-10 2	??-	??2	??-	??2	??-	??3	??-	??1	??-	???-	??3	??-	??-	??B
Methyl parahydroxybenzoate	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??A
															Propyl p-hydroxybenzoate	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??B
The EDTA disodium	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??A
															Sodium benzoate	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??B
Nicotiamide	??5	??5	??3	??-	??5	??5	??5	??3	??5	???-	??-	??5	??5	??A
															Pantothenylol	??3	??3	??1	??-	??3	??3	??3	??1	??3	???-	??-	??3	??3	??A
Tocopherol acetate	??2	??2	??0.5	??-	??2	??2	??2	??0.5	??2	??-	??-	??2	??2	??B

Retinyl palmitate	??0.1	??-	??-	??-	??-	??-	??0.05	??-	??-	??0.1	??-	??-	??-	??B
															Parsol?1789 3	??-	??1	??-	??1	??0.5	??-	??0.1	??-	??1	???-	??1	??-	??1	??B
Parsol?MCX 3	??-	??5	??-	??5	??2.5	??-	??0.5	??-	??5	???-	??5	??-	??5	??B
															Citric acid	??1	??0.5	??1	??0.5	??0.5	??1	??0.5	??1	??0.3	??0.75	??1	??1	??1	??A
Salicylic acid	??-	??0.5	??-	??0.5	??0.5	??-	??0.5	??-	??0.7	???-	??-	??-	??-	??A
															Triethanolamine	??0.1	??-	??-	??0.1	??0.1	??-	??-	??-	??0.1	???-	??-	??0.9	??0.5	??C
Sodium hydroxide	??-	??-	??0.1	??0.1	??0.1	??-	??-	??0.1	??-	??0.1	??-	???-	??-	??C
															Polyquaternary ammonium salt-10	??-	??-	??-	??1.0	??-	??-	??0.5	??-	??0.6	???-	??-	???-	??0.5	??B
Polymer KG 30 4	??-	??0.7	??-	??-	??0.7	??-	??-	??-	??-	??0.8	??-	???-	??-	??B
															Spice	??0.5	??0.5	??0.5	??0.5	??0.5	??-	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??E
Spermol	??3	??-	??-	??-	??2.6	??-	??-	??2.2	??-	??2.2	??-	??2.5	??-	??C
															Stearyl alcohol	??2	??-	??-	??-	??1.5	??-	??-	??3.2	??-	??1.1	??-	??1.6	??-	??C
Spermaceti/stearyl alcohol	??-	??-	??4	??-	??0.4	??-	??-	??-	??3.4	???-	??-	??-	??3.4	??C
															Tadenan	??2	??-	??2	??-	??-	??-	??-	??0.6	??-	??0.7	??-	??-	??-	??C
Natrosol?330?Plus	??1	??-	??-	??-	??0.4	??-	??-	??0.7	??0.6	???-	??-	??0.5	??0.25	??C
															Natrosol?250?HHR	??-	??-	??1	??-	??0.3	??-	??-	??-	??-	??1.2	??-	??-	??0.3	??C
Jaguar?HP?105 5	??-	??1.2	??-	??-	??-	??-	??-	??-	??-	???-	??0.8	??-	??-	??D
															Jaguar?C14S 5	??-	??-	??-	??1	??-	??-	??-	??-	??-	???-	??-	??-	??-	??D
Jaguar?C13S 5	??-	??-	??-	??-	??-	??1.2	??-	??-	??-	???-	??-	??-	?-	??D
															Xanthan gum	??-	??-	??-	??-	??-	??-	??2.0	??-	??-	???-	??-	??-	?-	??D
Sodium chloride	??-	??-	??0.1	??-	??-	??-	??0.5	??0.2	??-	??0.3	??-	??-	?-	??A
															Water	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	??A

Embodiment	??14	??15	??16	??17	??18	??19	??20	??21	??22	??23	??24	??25	??26
																% (weight)
Quaternary ammonium composition (seeing note)	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??A
															Glycerol	??32	??32	??32	??32	??32	??32	??32	??-	???-	??-	??-	??-	??-	??A
Urea	??-	??-	??-	??-	??-	??-	??-	??22	??22	??22	??22	??22	??22	??A
															Vaseline	??-	??-	??10	??-	??12	??15	??-	??-	??-	??10	??-	??12	??15	??B

Lanoline	??-	??-	??-	??7.5	??5	??-	??15	??-	??-	??-	??10	??10	??-	??B
															The Coronet lanoline 1	??-	??-	??-	??-	??-	??-	??5	??-	??-	??-	??-	??-	??-	??B
Super sterol ester 1	??-	??-	??-	??-	??-	??-	??5	??-	??-	??-	??-	??-	??-	??B
															Sefa cotton oil acid esters	??21	??21	??12	??12	??-	??-	??-	??21	??21	??12	??12	??-	??-	??B
Polydimethylsiloxane 10 centistokes	??-	??0.5	??0.5	??0.5	??-	??0.5	??0.5	??0.5	??-	??-	??-	??0.5	??0.5	??B
															Polydimethylsiloxane 1000 centistokes	??-	??1.0	??1.0	??1.0	??-	??1.0	??1.0	??1.0	??-	??-	??-	??1.0	??1.0	??B
The ring-type polymethyl siloxane	??-	??2.5	??2.5	??2.5	??-	??2.5	??2.5	??2.5	??-	??-	??-	??2.5	??2.5	??B
															Florasun?PEG-10 2	??-	??2	??-	??2	??-	??3	??-	??1	??-	??-	??3	??-	??-	??B
Methyl parahydroxybenzoate	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??A
															Propyl p-hydroxybenzoate	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??B
The EDTA disodium	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??A
															Sodium benzoate	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??B
Nicotiamide	??5	??5	??3		??5	??5	??5	??3	??5			??5	??5	??A
															Pantothenylol	??3	??3	??1		??3	??3	??3	??1	??3			??3	??3	??A
Tocopherol acetate	??2	??2	??0.5		??2	??2	??2	??0.5	??2			??2	??2	??B
															Retinyl palmitate	??0.1	??-	??-	??-	??-	??-	??0.05	??-	??-	??-	??-	??-	??0.15	??B
Parsol?1789 3	??-	??1	??-	??1	??0.5	??-	??0.1	??-	??1	??-	??1	??-	??1	??B
															Parsol?MCX 3	??-	??5	??-	??5	??2.5	??-	??0.5	??-	??5	??-	??5	??-	??5	??B
Citric acid	??1	??0.5	??1	??0.5	??0.5	??1	??0.5	??1	??0.3	??0.75	??1	??1	??1	??A
															Salicylic acid	??-	??0.5	??-	??0.5	??0.5	??-	??0.5	??-	??0.7	??-	?-	??-	??-	??A
Triethanolamine	??0.1	??-	??-	??0.1	??0.1	??-	??-	??-	??0.1	??-	??-	??0.9	??0.5	??C
															Sodium hydroxide	??-	??-	??0.1	??0.1	??0.1	??-	??-	??0.1	??-	??0.1	??-	??-	??-	??C
Polyquaternary ammonium salt-10	??-		??-	??1.0		??-	??0.5	??-	??0.6	??-	??-	??-	??0.5	??B
															Polymer KG 30 4	??-	??0.7	??-		??0.7	??-		??-	??-	??0.8	??-	??-	??-	??B
Spice	??0.5	??0.5	??0.5	??0.5	??0.5	??-	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??E
															Spermol	??3	??-	??-	??-	??2.6	??-	??-	??2.2	??-	??2.2	??-	??2.5	??-	??C
Stearyl alcohol	??2	??-	??-	??-	??1.5	??-	??-	??3.2	??-	??1.1	??-	??1.6	??-	??C
															Spermaceti/stearyl alcohol	??-	??-	??4	??-	??0.4	??-	??-	??-	??3.4	??-	??-	??-	??3.4	??C
Tadenan	??2	??-	??2	??-	??-	??-	??-	??0.6	??-	??0.7	??-	??-	??-	??C
															Natrosol?330?Plus	??1	??-	??-	??-	??0.4	??-	??-	??0.7	??0.6		??-	??0.5	??0.25	??C

Natrosol?250?HHR	??-	??-	??1	??-	??0.3	??-	???-	??-	??-	????1.2	??-	??-	??0.3	??C
															Jaguar?HP?105 5	??-	??1.2	??-	??-	??-	??-	???-	??-	??-	????-	??0.8	??-	??-	??D
Jaguar?C14S 5	??-	??-	??-	??1	??-	??-	????-	??-	??-	????-	??-	??-	??-	??D
															Jaguar?C13S 5	??-	??-	??-	??-	??-	??1.2	?????-	??-	??-	????-	??-	??-	??-	??D
Xanthan gum	??-	??-	??-	??-	??-	??-	??2.0	??-	??-	????-	??-	??-	??-	??D
															Sodium chloride	??-	??-	??0.1	??-	??-	??-	??0.5	??0.2	??-	????0.3	?-	??-	??-	??A
Water	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	??A

Embodiment	??27	??28	??29	??30	??31	??32	??33	???34	????35	??36	??37	??38	????39	??40	??41
																		% (weight)
Quaternary ammonium composition (seeing note)	??3	??3	??3	??3	??3	???3	????3	????3	????3	????3	??3	??3	????3	??3	??3	?A
																	Glycerol	??15	??16	??22	??9	??8	???9	??-	????32	????32	????32	??32	??32	????32	??32	??32	?A
Propylene glycol	??-	??16	??-	??-	??-	???5	??12	????-	????-	????-	??-	??-	????-	??-	??-	?A
																	Butanediol	??-	??-	??8	??8	??-	???8	??12	????-	????-	????-	??-	??-	????-	??-	??-	?A
Urea	??-	??-	??-	??12	??-	???2	??9	????-	????-	????-	??-	??-	????-	??-	??-	?B
																	Vaseline	??-	??-	??10	??-	??12	???15	??-	????-	????4	????7.5	??-	??12	????5	??-	??6	?B
Lanoline 1	??-	??-	??-	??7.5	??7.5	???-	??15	????-	????3.5	????-	??3	??-	????-	??-	??-	?B
																	The Coronet lanoline 1	??-	??-	??-	??-	??-	???-	??-	????-	????7	????-	??6.7	??-	????-	??6	??-	?B
Super sterol ester 1	??-	??-	??-	??-	??-	???-	??-	????-	????3.5	????-	??6.5	??-	????3	??6	??3	?B
																	2-Methylpentadecane	??-	??-	??-	??-	??-	???-	??-	????-	????-	????5	??-	??3	????-	??-	??3	?B
Isononyl isononanoate	??-	??-	??-	??-	??-	???-	??-	????-	????-	????3	??-	??5	????-	??-	??-	?B
																	Sefa cotton oil acid esters	??21	??21	??12	??12	??-	???-	??-	????13	????-	????8	??-	??-	????8	??12	??10	?B
Sefa docosane acid esters	??-	??-	??-	??-	??-	???-	??-	????9	????-	????-	??3	??-	????5	??-	??-	?B
																	Polydimethylsiloxane 10 centistokes	??-	??0.5	??0.5	??0.5	??-	??0.5	??0.5	????0.5	????-	????-	??-	??0.5	????0.5	??-	??-	?B
Polydimethylsiloxane 1000 centistokes	??-	??1.0	??1.0	??1.0	??-	??1.0	??1.0	????1.0	????-	????-	??-	??1.0	????1.0	??-	??-	?B
																	The ring-type polymethyl siloxane	??-	??2.5	??2.5	??2.5	??-	??2.5	??2.5	????2.5	????-	????-	??-	??2.5	????2.5	??-	??-	?B
Florasun?PEG-10 2	?-	??2	????-	??2	??-	??3	??-	????1	????-	????-	??3	??-	?????-	??2.5	??-	?B

Methyl parahydroxybenzoate	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	?A
																	Propyl p-hydroxybenzoate	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	?B
The EDTA disodium	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	?A
																	Sodium benzoate	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	?B
Nicotiamide	??3	??5	??5	??-	??-	??5	??5	??5	??3	??3	??-	??5	??5	??5	??3	?A
																	Pantothenylol	??1	??3	??3	??-	??-	??3	??3	??3	??1	??1	??-	??3	??3	??3	??1	?A
Tocopherol acetate	??0.5	??2	??2	??-	??-	??2	??2	??2	??0.5	??0.5	??-	??2	??2	??2	??0.5	?B
																	Retinyl palmitate	??-	??-	??-	??0.1	??-	??0.05	??-	??-	??0.1	??-	??-	??-	??-	??-	??-	?B
Parsol?1789 3	??-	??1	??-	??1	??0.5	??-	??1	??-	??1	??-	??1	??-	??0.1	??1	??-	?B
																	Parsol?MCX 3	??-	??5	??-	??5	??2.5	??-	??5	??-	??5	??-	??5	??-	??0.5	??5	??-	?B
Citric acid	??1	??0.5	??1	??0.5	??0.5	??1	??0.5	??1	??0.3	?0.75	??1	??1	??1	??1	??-	?A
																	Salicylic acid	??-	??0.5	??-	??0.5	??0.5	??-	??0.5	??-	??0.7	??-	??-	??-	??-	??-	??0.5	?A
Triethanolamine	??0.1	??-	??-	??0.1	??0.1	??-	??-	??-	??0.1	??-	??-	??0.9	??0.5	??-	??-	?C
																	Sodium hydroxide	??-	??-	??0.1	??0.1	??0.1	??-	??-	??0.1	??-	??0.1	??-	??-	??-	??-	??0.6	?C
Polyquaternary ammonium salt-10	??-	??-	??-	??1.0	??-	??-	??0.5	??-	??0.6	??-	??-	??-	??0.5	??1.0	??-	?B
																	Polymer KG 30 4	??-	??0.7	??-	??-	??0.7	??-	??-	??-	??-	??0.8	??-	??-	??-	??-	??0.8	?B
Spice	??0.5	??0.5	??0.5	??0.5	??0.5	??-	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	?E
																	Spermol	??3	??-	??-	??-	??2.6	??-	??-	??2.2	??-	??2.2	??-	??2.5	??-	??-	??3.2	?C
Stearyl alcohol	??2	??-	??-	??-	??1.5	??-	??-	??3.2	??-	??1.1	??-	??1.6	??-	??-	??2.6	?C
																	Spermaceti/stearyl alcohol	??-	??-	??4	??-	??0.4	??-	??-	??-	??3.4	??-	??-	??-	??3.4	??-	??-	?C
Tadenan	??2	??-	??2	??-	??-	??-	??-	??0.6	??-	??0.7	??-	??-	??-	??-	??0.2	?C
																	Natrosol?330?Plus	??1	??-	??-	??-	??0.4	??-	??-	??0.7	??0.6	??-	??-	??0.5	??0.25	??-	??0.6	?C
Natroso1?250?HHR	??-	??-	??1	??-	?0.3	??-	??-	??-	??-	??1.2	??-	??-	??0.3	??-	??-	?C
																	JaguarHP?105 5	??-	??1.2	??-	??-	??-	??-	??-	??-	??-	??-	??0.8	??-	??-	??-	??-	?D
Jaguar?C14S 5	??-	??-	??-	??1	??-	??-	??-	??-	??-	??-	??-	??-	??-	??-	??-	?D
																	Jaguar?C13S 5	??-	??-	??-	??-	??-	??1.2	??-	??-	??-	??-	??-	??-	??-	??0.8	??-	?D
Xanthan gum	??-	??-	??-	??-	??-	??-	??3.0	??-	??-	??-	??-	??-	??-	??-	??-	?D
																	Sodium chloride	??-	??-	??0.1	??-	??-	??-	??0.5	??0.2	??-	??0.3	??-	??-	??-	??0.2	??0.1	?A
Water	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	?A

Embodiment	??42	??43	??44	??45	??46	??47	??48	??49	??50	??51	??52	??53	??54	??55	??56
																		% (weight)
Quaternary ammonium composition (seeing note)	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	?A
																	Glycerol	??15	??16	??22	??9	??8	??9	??-	??32	??32	??32	??32	??32	??32	??32	??32	?A
Propylene glycol	??-	??16	??-	??-	??-	??5	??12	??-	??-	??-	??-	??-	??-	??-	??-	?A
																	Butanediol	??-	??-	??8	??8	??-	??8	????12	??-	??-	??-	??-	??-	??-	??-	??-	?A
Urea	??-	??-	??-	??12	??-	??2	??9	??-	??-	??-	??-	??-	??-	??-	??-	?B
																	Vaseline	??-	??-	??10	??-	??12	??15	??-	??-	??4	??7.5	??-	??12	??5	??-	??6	?B
Lanoline 1	???-	??-	??-	??7.5	??7.5	??-	??15	??-	??3.5	??-	??3	??-	??-	??-	??-	?B
																	The Coronet lanoline 1	??-	??-	??-	??-	??-	??-	??-	??-	??7	??-	??6.7	??-	??-	??6	??-	?B
Super sterol ester 1	??-	??-	??-	??-	??-	??-	??-	??-	??3.5	??-	??6.5	??-	??3	??6	??3	?B
																	2-Methylpentadecane	??-	??-	??-	??-	??-	??-	??-	??-	??-	??5	??-	??3	??-	??-	??3	?B
Isononyl isononanoate	??-	??-	??-	??-	??-	??-	??-	??-	??-	??3	??-	??5	??-	??-	??-	?B
																	Sefa cotton oil acid esters	??21	??21	??12	??12	??-	??-	??-	??13	??-	??8	??-	??-	??8	??12	??10	?B
Sefa docosane acid esters	??-	??-	??-	??-	??-	??-	??-	??9	??-	??-	??3	??-	??5	??-	??-	?B
																	Polydimethylsiloxane 10 centistokes	??-	??0.5	??0.5	??0.5	??-	??0.5	??0.5	??0.5	??-	??-	??-	??0.5	??0.5	??-	??-	?B
Polydimethylsiloxane 1000 centistokes	??-	??1.0	??1.0	??1.0	??-	??1.0	??1.0	??1.0	??-	??-	??-	??1.0	??1.0	??-	??-	?B
																	The ring-type polymethyl siloxane	??-	??2.5	??2.5	??2.5	??-	??2.5	??2.5	??2.5	??-	??-	??-	??2.5	??2.5	??-	??-	?B
Florasun?PEG-10 2	??-	??2	??-	??2	??-	??3	???-	??1	??-	??-	??3	??-	??-	??2.5	??-	?B
																	Methyl parahydroxybenzoate	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	?A
Propyl p-hydroxybenzoate	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	?B
																	The EDTA disodium	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	?A
Sodium benzoate	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	?B
																	Nicotiamide	??3	??5	??5	??-	??-	??5	??5	??5	??3	??3	??-	??5	??5	??5	??3	?A
Pantothenylol	??1	??3	??3	??-	??-	??3	??3	??3	??1	??1	??-	??3	??3	??3	??1	?A
																	Tocopherol acetate	0.5	??2	??2	??-	??-	??2	??2	??2	??0.5	??0.5	??-	??2	??2	??2	??0.5	?B

Retinyl palmitate	??-	??-	??-	??-	??-	??-	??-	??-	????0.05	???-	??-	??0.1	??-	??-	??-	??B
																	Parsol?l789 3	??-	??1	??-	??1	??0.5	??-	??1	??-	????1	???-	??1	??-	??0.1	??1	??-	??B
Parsol?MCX 3	??-	??5	??-	??5	??2.5	??-	??5	??-	????5	???-	??5	??-	??0.5	??5	??-	??B
																	Citric acid	??1	??0.5	??1	??0.5	??0.5	??1	??0.5	??1	????0.3	???0.75	??1	??1	??1	??1	??-	??A
Salicylic acid	??-	??0.5	??-	??0.5	??0.5	??-	??0.5	??-	????0.7	???-	??-	??-	??-	??-	??0.5	??A
																	Triethanolamine	??0.1	??-	??-	??0.1	??0.1	??-	??-	??-	????0.1	???-	??-	??0.9	??0.5	??-	??-	??C
Sodium hydroxide	??-	??-	??0.1	??0.1	??0.1	??-	??-	??0.1	????-	???0.1	??-	??-	??-	??-	??0.6	??C
																	Polyquaternary ammonium salt-10	??-	??-	??-	??1.0	??-	??-	??0.5	???-	????0.6	???-	??-	??-	??0.5	??1.0	??-	??B
Polymer KG 30 4	??-	??0.7	??-	??-	??0.7	??-	??-	???-	????-	???0.8	??-	??-	??-	??-	??0.8	??B
																	Spice	??0.5	??0.5	??0.5	??0.5	??0.5	??-	??0.5	??0.5	????0.5	???0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??E
Spermol	??3	??-	??-	??-	??2.6	??-	??-	??2.2	????-	???2.2	??-	??2.5	??-	??-	??3.2	??C
																	Stearyl alcohol	??2	??-	??-	??-	??1.5	??-	??-	??3.2	????-	???1.1	??-	??1.6	??-	??-	??2.6	??C
Spermaceti/stearyl alcohol	??-	??-	??4	??-	??0.4	??-	??-	??-	????3.4	???-	??-	??-	??3.4	??-	??-	??C
																	Tadenan	??2	??-	??2	??-	??-	??-	??-	??0.6	????-	???0.7	??-	??-	??-	??-	??0.2	??C
Natrosol?330?Plus	??1	??-	??-	??-	??0.4	??-	??-	??0.7	????0.6	???-	??-	??0.5	??0.2	??-	??0.6	??C
																	Natrosol?250?HHR	??-	??-	??1	??-	??0.3	??-	??-	??-	????-	???1.2	??-	??-	??0.3	??-	??-	??C
Jaguar?HP?105 5	??-	??1.2	??-	??-	??-	??-	??-	??-	????-	???-	??0.8	??-	??-	??-	??-	??D
																	Jaguar?C14S 5	??-	??-	??-	??1	??-	??-	??-	??-	????-	???-	??-	??-	??-	??-	??-	??D
Jaguar?C13S 5	??-	??-	??-	??-	??-	??1.2	??-	??-	????-	???-	??-	??-	??-	??0.8	??-	??D
																	Xanthan gum	??-	??-	??-	??-	??-	??-	??3.0	??-	????-	???-	??-	??-	??-	??-	??-	??D
Sodium chloride	??-	??-	??0.1	??-	??-	??-	??0.5	??0.2	????-	???0.3	??-	??-	??-	??0.2	??0.1	??A
																	Water	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	??A

1: derive from Croda

2: derive from Floratech, AZ, USA

3: derive from Hoffman La Roche, NJ, USA

4: derive from Amerchol, NJ, USA

5: derive from Rhodi a, NJ, USA note

● embodiment 1,2,3,4,5,6,7,8,9,10,15,16,17,18,19,20,21,22,23,24,25,

26，27，28，31，33，34，35，36，37，38，41，45，47，48，49，50，51，52，53，54，55，

In 56, that quaternary ammonium compound adopts is N, N-two (canola acyl group-oxygen-ethyl)-N-methyl,

N-(2-ethoxy) methylsulfuric acid ammonium, available from Goldschmidt, commodity are called Rewoquat V3620

● embodiment 11,25, and in 29, that quaternary ammonium compound adopts is N, N-two (canola acyl group-oxygen-

Ethyl)-and the N-methyl, N-(2-ethoxy) methylsulfuric acid ammonium, available from Goldschmidt, commodity are by name

Rewoquat?WE18

● embodiment 12,30, and in 32, that quaternary ammonium compound adopts is N, N-two (canola acyl group-oxygen-

Ethyl)-and the N-methyl, N-(2-ethoxy) ammonium chloride, available from Goldschmidt, exploitation material (WE25)

● embodiment 13,39, and in 40,42, what quaternary ammonium compound adopted is two (the h-tallow acylamino-s of methyl

Ethyl) (2-ethoxy) methylsulfuric acid ammonium, available from Goldschmidt, commodity are called Varisoft 110.

● embodiment 14,43, and in 44, that quaternary ammonium compound adopts is two (tallow acylamino-the ethyl) (2-of methyl

Ethoxy) methylsulfuric acid ammonium, available from Goldschmidt, commodity are called Varisoft 222.Method is used to comprise the embodiment of component C:

1. pre-composition 1: each component under the condition that is higher than selected quaternary ammonium compound conversion temperature in the mixed A group, the quaternary ammonium compound and the water that keep scheduled volume do not add.Violent mixed this pre-composition.

2. pre-composition 2: remaining quaternary ammonium compound and water in each component in B and the C group and the above pre-composition 1 is mixed.Be heated to more than the fusing point of quaternary ammonium compound and oils.

3. pre-composition 1 and 2 is mixed, and be cooled to 40 ℃, stir adding essence.Be used to comprise the embodiment of component D:

1. pre-composition 1: each component under the condition that is higher than selected quaternary ammonium compound conversion temperature in the mixed A group, the water that keeps scheduled volume does not add.Violent mixed this pre-composition.

2. pre-composition 2: stir down, and remaining water in each component in the D group and the above pre-composition 1 is mixed.

With pre-composition 1 and 2 and B and E group in each component mixed.Vigorous stirring.

The compositions of the foregoing description provides good skin care benefits, as good moist effect, good hydration, good skin usability, good skin softness and/or good skin flatness, detrimental effect such as greasy, cohesiveness or sticky property are low simultaneously.

Claims (10)

1. cosmetic composition, comprising:

(a) at least aly be easy to biodegradable quaternary ammonium composition; With

(b) wetting agent of at least 5% weight.

2. according to the compositions of claim 1, wherein said compositions comprises the quaternary ammonium composition that is easy to degrade of 0.01%, more preferably at least 1% weight.

3. according to the compositions of claim 1 or 2, wherein said compositions comprises the wetting agent of at least 7.5%, more preferably at least 10% weight.

4. according to the compositions of aforementioned each claim, wherein said wetting agent is selected from glycerol, urea, butanediol, Polyethylene Glycol and derivant thereof, and their mixture.

5. according to the compositions of aforementioned each claim, wherein said compositions comprises vesicle, and wherein said vesicle comprises quaternary ammonium composition and wetting agent.

6. according to the compositions of aforementioned each claim, wherein the quaternary ammonium composition is selected from those that can form vesicle in polar solvent, detects by microscopic analysis.

7. according to the compositions of aforementioned each claim; wherein the quaternary ammonium composition is selected from N; N-two (canola acyl group-oxygen-ethyl)-N; N-alkyl dimethyl ammonium chloride, N; N-two (canola acyl group-oxygen-ethyl)-N-methyl; N-(2-ethoxy) methylsulfuric acid ammonium, N, N-two (canola acyl group-oxygen-ethyl)-N-methyl, N-(2-ethoxy) ammonium chloride and their mixture.

8. according to the compositions of aforementioned each claim, wherein said compositions also comprises emollient.

9. according to the compositions of aforementioned each claim, wherein said compositions comprises and is less than 5%, preferably is less than 3%, the anion surfactant of preferred 0% weight.

10. according to the application of compositions in nursing skin of aforementioned each claim.