CN1371270A - Cosmetic method - Google Patents

Abstract

According to the present invention there is provided a cosmetic method comprising: (i) applying to the skin a composition comprising: (a) at least one quaternary ammonium agent; and (b) humectant; (ii) rinsing the skin. The methods of the present invention give good skin care benefits, such as good moisturisation, good hydration, good skin feel, good skin softness and/or good skin smoothness, with low levels of negatives such as greasiness, stickiness or tack.

Description

Beauty method

Technical field

The present invention relates to beauty method.Particularly, the present invention relates to nursing skin, the beauty method of moist effect (moisturisation), hydration, dermal sensation, skin softness and/or the skin smoothness that provides.

Background of invention

Skin is by the several layers cellularity, and these cells cover and protect the keratin and the collagen fiber albumen of the skeleton that constitutes skin texture.The outermost layer of these cellular layers is called horny layer, and the known 25nm albumen bundle that is centered on by the thick cellular layer of 8nm constitutes.The general penetrable cuticle layer of anion surfactant and organic solvent, and destroy the integrity of skin through degreasing (promptly removing the lipid in the horny layer).Thisly will produce harsh feeling, thereby finally can make surfactant or solvent and keratin interact, produce stimulation skin surface topology structural damage effect.

Recognize that at present maintenance horny layer suitable moisture gradient from inside to outside is extremely important to its function.These moisture are considered to cuticular plasticizer (plasticizer) sometimes, its most ex vivos.If humidity is low excessively, under at cold climate, the moisture deficit of outer layer of stratum corneum is organized suitable plasticising thereby can not make, and skin can be peeled and be produced scratchiness.When in the horny layer during moisture deficit, percutaneous permeability also can reduce to a certain extent.On the other hand, the outside excess moisture of skin will make horny layer finally absorb its deadweight 3-5 bound water doubly.This can make skin turgor and wrinkling, and causes skin that the permeability of water and other polar molecule is increased to about 2-3 doubly.

Therefore, need a kind of method, this method can be ignored the deleterious interaction that skin may run in washing, work and amusement, still helps horny layer to keep its optimal isolation and water retention property.

In the past, the method for nursing skin often is to adopt the compositions that comprises one or more " skin beneficiating ingredient (skinbenefit agents) ".These skin beneficiating ingredients are normally water miscible.It is for example, a kind of that to provide highly the approach of the effect of moistening to skin be to introduce polyalcohols material which can retain moisture such as glycerol in compositions.But the high and skin composition that therefore has a height moistness of polyhydric alcohol content has sticky because of on being applied to skin the time or adhesion is felt, thereby makes consumer feel bad.Seem the amount of skin beneficiating ingredient and provide to skin between the effect of compositions of beneficial effect to exist direct relation.But in fact the content of skin beneficiating ingredient is high more, and the danger that produces associated unfavorable effect is also just high more.The method of alleviating this problem is to use water rinse skin.But rinsing skin will be washed skin beneficiating ingredient off again, especially when skin beneficiating ingredient when being water miscible.

Known quaternary ammonium composition (quaternary ammonium agents) also can be used in the cosmetic composition.Referring to for example WO-A-99/27904, WO-A-96/32089 and EP-A-789,076.And US-A-5 also discloses skin care compositions and methods in 804,205, and it it is said and the moist effect of height can be provided and can not stay " adhesion " or " sticky " residue.Contain the nonirritating hydrophobic microsphere that 2 quaternary ammonium compound, wetting agent and mean diameters with alkyl of 16-22 carbon atom are lower than 50 μ m in the compositions.It is said that hydrophobic polymerizing microballoons has reduced and wetting agent content high relevant " cohesiveness " significantly.US-A-5 also discloses the method that adopts such compositions nursing skin in 804,205.But quaternary ammonium composition commonly used normally is difficult for biodegradable, therefore harmful to environment in the prior art.

Be surprised to find that the compositions nursing skin that comprises with containing at least a quaternary ammonium composition and wetting agent at present, beauty method with water rinse can provide useful skin effect then, as good moist effect, hydration, dermal sensation, skin softness and skin smoothness, and unfavorable effect such as greasy, sticky property or cohesiveness are low.

Although do not wish to be subjected to the restriction of any theory, believe that in the inventive method compositions for use quaternary ammonium composition of the present invention can make wetting agent form vesicle, and impels them to be deposited on the skin.Can make like this wetting agent smooth, be applied on the skin equably, and cohesiveness/sticky property/greasy is minimum.Believe that rinse step can make the sticky or oily unnecessary wetting agent of dermal sensation further reduce described unfavorable effect by eccysis.The method regular meeting that comprises rinse step in the prior art is the eccysis beneficiating ingredient too much.And adopt method of the present invention, and believe that the quaternary ammonium composition can reduce the loss of beneficiating ingredient, help to alleviate common unfavorable effect simultaneously.Even contain the wetting agent of high percentage composition in the inventive method in the compositions for use, for example during 30% weight, low unfavorable effect is only arranged also.And, believe that also the quaternary ammonium composition helps to reduce scattering and disappearing of wetting agent on the skin that causes because of the water in environmental factors such as the rinse step or with the friction or the friction in the cleaning process of medicated clothing.In addition, believe that the quaternary ammonium composition itself has the skin protection beneficial effect, as good moist effect, good skin sense, good skin softness.

Summary of the invention

The invention provides beauty method, this method comprises:

(i) on skin, use the compositions that (apply) comprises following compositions:

(a) at least a quaternary ammonium composition;

(b) wetting agent;

(ii) rinsing skin.

Method of the present invention has been brought good skin care benefits, and as good moist effect, good hydration, good skin sense, good skin softness and/or good skin smoothness, and detrimental effect such as greasy feeling, sticky sense or cohesiveness are low.

Detailed Description Of The Invention

Method of the present invention is included in and uses the compositions that contains at least a quaternary ammonium composition and wetting agent, rinsing skin then on the skin.Beauty method

Method of the present invention is included in and uses the compositions that comprises at least a quaternary ammonium composition and wetting agent, rinsing skin then on the skin.The compositions that is used for the inventive method will be explained in more detail hereinafter.

The skin nursing effect that method of the present invention can provide, as good moist effect, good hydration, good skin usability, good skin softness and/or good skin smoothness, and unfavorable effect such as greasy, sticky property or cohesiveness are low.Especially, method of the present invention has been brought good moist effect and hydration benefit to skin, but can not make dermal sensation greasy.Method of the present invention need comprise following steps:

(i) on skin, use the compositions that comprises following compositions:

(a) at least a quaternary ammonium composition; With

(b) wetting agent;

(ii) rinsing skin.

Step (i) can be implemented on moist skin or dry skin.For obtain giving prominence to moisten and/or the hydration effect, preferred steps (i) is implemented on dry skin.Therefore, the inventive method preferred aspect comprises:

(i) on dry skin, use the compositions that contains at least a quaternary ammonium composition and wetting agent;

(ii) rinsing skin.

Another preferred aspect of the present invention is included in the said method, and compositions is used for moist skin in addition.Therefore, preferable methods comprises:

(i) compositions that will contain at least a quaternary ammonium composition and wetting agent is applied on the dry skin;

(ii) at the following rinsing skin of shower (shower);

(iii) reuse described compositions; And

(iv) rinsing once more.

Most damages to human body skin are to be repeated repeatedly to be exposed in the compositions that contains surfactant by skin in cleaning process to produce.Have now found that this damage can be by method alleviation of the present invention.Therefore another preferred aspect of the inventive method comprises:

(i) adopt the compositions that contains surfactant to clean skin;

(ii) rinsing skin;

The compositions that (iii) will contain at least a quaternary ammonium composition and wetting agent is used for moist skin;

(iv) rinsing skin.

Find also now that method of the present invention is particularly useful when the part of method of the present invention being introduced as the cleaning procedure of routine.Therefore another preferred aspect of the inventive method comprises:

(i) application comprises following compositions on skin:

(a) at least a quaternary ammonium compound;

(b) wetting agent; With

(ii) rinsing skin;

(iii) repeating step (i) and (ii) in 48 hours.

Also find now method of the present invention is being introduced when shaving the part of program method particularly suitable of the present invention as routine.Therefore, the preferred aspect of another of the inventive method comprises:

(i) shave (shave) skin;

(ii) randomly, rinsing skin;

(iii) on skin, use and comprise following compositions:

(a) at least a quaternary ammonium compound;

(b) wetting agent; With

(iv) rinsing skin.

Method of the present invention can also be used for alleviating because of skin be exposed to damage that ultraviolet radiation causes, in swimming or similarly contact the damage that causes in the water exercise with water or contact the skin injury that causes during in bathing with water.Compositions

Preferably, compositions for use contains vesicle (vesicle) in the inventive method, comprises quaternary ammonium composition and wetting agent in this vesicle.Term used herein " vesicle " is meant and is arranged as one or more bilayers sealing, that be generally spherical form that described bilayer comprises quaternary ammonium composition hereinafter described.Comprise quaternary ammonium composition and wetting agent in the preferred described vesicle.In compositions for use of the present invention, vesicle is preferred to be spherical substantially.The vesicle that exists in the compositions in the present invention can detect by microscopic analysis (adopting Nikon Eclipse E800 microscope to amplify 60 times polarized light microscopy method).

The number average size of the vesicle among preferred the present invention is 0.01 μ m-30 μ m, more preferably 0.1 μ m-15 μ m.

Compositions for use is forms such as cream frost, emulsion (lotion), gel in preferred the inventive method.Be preferred for compositions in the inventive method at the continuous oil-in-water emulsion of one or more oil phases of aqueous phase, each oil phase contains single oily components or is the mixture of the oily components of miscible or homogenizing form, but described different oil phase contains the material that differs from one another or the combination of each material.

Compositions for use contains and is less than 10% in preferred the inventive method, preferably is less than 5%, more preferably less than 3%, and the more preferably anion surfactant of 0% (weight) also.

Compositions of the present invention preferably is mixed with viscosity and is at least about 1, and 000mPa.s preferably is about 1,000 to about 300,000mPa.s, be more preferably 2,500 to about 250,000mPa.s, particularly be about 5,000 to about 200, (26.8 ℃ of 000mPa.s, net phase, Brookfield DV-II+ spindle CP52/CP41) product.The quaternary ammonium composition

Compositions among the present invention must contain at least a quaternary ammonium composition.Be applicable to that any quaternary ammonium composition in the cosmetic composition all can be used for the present invention.Term used herein " quaternary ammonium composition " is meant the chemical compound with quaternary nitrogen atoms or the mixture of chemical compound, and wherein quaternary nitrogen atoms is replaced by one or more, preferred two parts that contain 6 or 6 above carbon atoms.Be preferred for quaternary ammonium composition of the present invention and be being easy to biodegradable.Term used herein " is easy to " to be meant the test according to OECD307 biodegradable, and at least 60% chemical compound is mineralising in 28 days.Be preferred for quaternary ammonium composition of the present invention and be selected from those that quaternary nitrogen replaced by two parts, wherein each part comprise more than 10 or 10, preferred carbon atom more than 12 or 12.Highly preferredly be used for quaternary ammonium composition of the present invention and be selected from and can form those of vesicle at polar solvent, it can detect by microscopic analysis (adopting NikonEclipse E800 microscope to amplify 60 times polarized light microscopy detection).

Contain at least 0.01% (weight) in the preferred compositions of the present invention, more preferably at least 0.1% (weight), more preferably at least 1.5% (weight) also, the further more preferably quaternary ammonium composition of at least 3% (weight).

Being preferred for quaternary ammonium composition of the present invention is selected from:

(a) quaternary ammonium compound shown in the general formula (I):

R wherein ₁And R ₂Be C independently ₁-C ₄Alkyl or C ₁-C ₄Hydroxyalkyl or hydrogen.R ₃And R ₄Be to have about 8 alkyl or alkenyls independently to about 22 carbon atoms.X ^-Be the become salt anionic compatible with other adjuvant composition with quaternary ammonium compound.

The preferred quaternary ammonium compound of this apoplexy due to endogenous wind is the wherein R with general formula (I) ₁And R ₂Be methyl or ethoxy and R ₃And R ₄Be the amine that comprises the seasonization of the straight or branched alkyl of at least 11 carbon atoms, preferred at least 15 carbon atoms or alkenyl.

(b) general formula (II) or (III) shown in quaternary ammonium compound:

Each R wherein ₅The unit is independently from each other the C of hydrogen, side chain or straight chain ₁-C ₆Alkyl, side chain or straight chain C ₁-C ₆Hydroxyalkyl and their mixture, preferably methyl and ethoxy; Each R ₆The unit is straight or branched C independently of one another ₁₁-C ₂₂Alkyl, straight or branched C ₁₁-C ₂₂Alkenyl, and their mixture; X ^-Be can be compatible with the adjuvant composition with the skin care active composition anion; M is 1-4, is preferably 2; N is 1-4, is preferably 2, and Q is selected from following carbonyl unit:

R wherein ₇Be hydrogen, C ₁-C ₄Alkyl, C ₁-C ₄Hydroxyalkyl, and their mixture.

In the example of above-mentioned quaternary ammonium compound, unit-QR ₆Containing generally is the fatty acyl group unit of being derived and being obtained by the triglyceride source.The triglyceride source is preferably derived from Adeps Bovis seu Bubali, partially hydrogenated Adeps Bovis seu Bubali, Adeps Sus domestica, partially hydrogenated Adeps Sus domestica, vegetable oil and/or partially hydrogenated vegetable oil, as low erucic acid rapeseed oil, safflower oil, Oleum Arachidis hypogaeae semen, rapeseed oil, sunflower oil, Semen Maydis oil, soybean oil, tall oil, Testa oryzae wet goods, and these oily mixture.

Counter ion counterionsl gegenions X in the above-claimed cpd ^-Can be any compatible anion, the anion of strong acid preferably, for example chloride ion, bromide ion, methylsulfate, ethyl sulphate, sulfate radical, nitrate anion etc. are more preferably chloride ion or methylsulfate.Anion also can but less double charge, the X in this case of preferably having ^-Represent half of group.

The preferred quaternary ammonium compound of the present invention is diester and/or diamides quaternary ammonium (DEQA) chemical compound, and diester and diamides are shown in general formula (II), and wherein carbonyl Q is selected from:

Adeps Bovis seu Bubali, low erucic acid rapeseed oil and Petiolus Trachycarpi oil are convenient and the economic unitary source of fatty acyl group, are suitable in the present invention as R ₆The unit.

Counter ion counterionsl gegenions X ^-Can be chloride ion, bromide ion, methylsulfate, formate, sulfate radical, nitrate anion and their mixture.In fact anion X ^-Only the counter ion counterionsl gegenions as positively charged quaternary ammonium compound exist.Do not consider within the scope of the invention it is defined as any specific anion.

In the present invention, when regulation is used diester, wherein will comprise monoesters and three esters by the common existence that brings in the preparation process.

(c) general formula (IV) or (V) shown in quaternary ammonium compound:

R wherein ₉Be acyclic aliphatic C ₁₅-C ₂₁Alkyl, and R ₁₀Be C ₁-C ₆Alkyl or alkenyl (alkylene).

These pKa values are no more than about 4 ammonium compounds, when disperseing in aqueous solution, can produce cationic charge on the spot, and condition is that the pH of final composition is no more than about 6.

(d) general formula (VI) or (VII) shown in quaternary ammonium compound:

R wherein ₉And R ₁₀As hereinbefore defined, R ₁₁Be selected from C ₁-C ₄Alkyl and hydroxyalkyl.

Counter ion counterionsl gegenions X ^-Can be chloride ion, bromide ion, methylsulfate, formate, sulfate radical, nitrate anion, and their mixture.In fact anion X ^-Only the counter ion counterionsl gegenions as positively charged quaternary ammonium compound exist.Do not consider in the scope of the invention it is defined as any specific anion.

(e) general formula (VIII) or (IX) shown in quaternary ammonium compound:

Wherein n is 1-6, R ₉Be selected from no cyclic aliphatic C ₁₅-C ₂₁Alkyl, and R ₁₂Be selected from C ₁-C ₄Alkyl and hydroxyalkyl.

It is about 4 that the pKa value of these ammonium compoundss (VIII) is no more than, and can produce cationic charge on the spot when disperseing in aqueous solution, and condition is that the pH of final composition is no more than about 6.

Counter ion counterionsl gegenions X ^-(IX) can be chloride ion, bromide ion, methylsulfate, formate, sulfate radical, nitrate anion, and composition thereof.In fact anion X ^-Only the counter ion counterionsl gegenions as positively charged quaternary ammonium compound exist.Do not plan in the scope of the invention it is defined as any specific anion.

(f) general formula (X), (XI), (XII) or (XIII) shown in quaternary ammonium compound:

R wherein ₅, R ₆, Q, n and X ^-As mentioned general formula (II) and (III) in definition, R ₁₃Be selected from C ₁-C ₆Alkylidene, ethylidene preferably, z is 0-4.

(g) mixture of above-mentioned quaternary ammonium compound.

Be preferred for quaternary ammonium composition among the present invention and be described in above-mentioned (b) part those.Particularly, diester shown in the preferred above-mentioned general formula (II) and/or diamides quaternary ammonium (DEQA) chemical compound.The preferred diester that is used for the present invention is R wherein ₅, R ₆, and X ^-As previously mentioned, and Q be the chemical compound shown in the general formula (II) as follows:

The diamides that is preferred among the present invention is R in the chemical compound shown in the general formula (II) ₅, R ₆And X ^-As previously mentioned, and Q be as follows those:

The example that is applicable to the preferred quaternary ammonium compound of the compositions among the present invention is: N; N-two (canola acyl group-oxygen-ethyl)-N; the N-alkyl dimethyl ammonium chloride; N, N-two (canola acyl group-oxygen-ethyl)-N-methyl, N-(2-ethoxy) methylsulfuric acid ammonium; N; N-two (canola acyl group-oxygen-ethyl)-N-methyl, N-(2-ethoxy) ammonium chloride, and their mixture.Be particularly preferred for the N of being of the present invention, N-two (canola acyl group-oxygen-ethyl)-N-methyl, N-(2-ethoxy) methylsulfuric acid ammonium.

Although the quaternary ammonium compound derived from " canola acyl group (canolyl) " fatty acyl group is preferred; but the example of the quaternary ammonium compound that other is suitable for can be derived from wherein above-mentioned " canola acyl group " by following displaced fatty acyl group: " Adeps Bovis seu Bubali acyl group, cocoyl, palmityl (palmyl), lauroyl, oleoyl, Oleum Ricini acyl group, stearyl, palmityl (palmityl) " substitutes, and these are corresponding to derived from the unitary triglyceride of fatty acyl group source.These alternative fatty acyl group sources can comprise saturated entirely, perhaps preferably to the undersaturated chain of small part.Wetting agent

Second of compositions for use fundamental is wherein to contain wetting agent (humectant) in the inventive method.Term used herein " wetting agent " is meant the material that can make skin have the water conservation effect.Compositions among preferred the present invention comprises at least 1% (weight), more preferably at least 5% (weight), more preferably at least 10% (weight) also, further preferably at least 20% (weight), the especially preferably wetting agent of at least 30% (weight).

Any wetting agent that uses in the cosmetic composition is all used in the present invention.The non-limiting example that can be used for wetting agent of the present invention is disclosed in WO 98/22085, WO 98/18444 and WO97/01326.The wetting agent that is preferred for this is selected from, but is not limited to: aminoacid and derivant thereof, as proline and arginine aspartate; 1,3 butylene glycol, propylene glycol and water; and Korean pine platymiscium (codiumtomentosum) extract, collagen amino acid or peptide, kreatinin; diglycerol, biological polyoses glue-1 (biosaccharide-1), glucosamine salt; glucuronate; glutamate, Glu, polyethylene glycol glycerol ether (for example glycerin polyoxyethylene ether 20), glycerol; glycerol list propoxylate; glycogen, hexanediol, Mel and extract thereof or derivant; hydrogenated starch hydrolysates; the hydrolysis mucopolysaccharide, inositol, keratin aminoacid; urea; LAREX A-200 (available from Larex), glycosaminoglycans, methoxyl group PEG-10; methyl gluceth-10 and-20 (all can be available from Amerchol; be positioned at Edison, NJ), methyl glucoside; the 3-methyl isophthalic acid; the 3-butanediol, N-acetyl glucosamine salt, Polyethylene Glycol and derivant thereof are (as PEG 15 butanediols; PEG 4; PEG 5 tetramethylolmethanes, PEG 6, and PEG 8; PEG 9); tetramethylolmethane, 1, the 2-pentanediol; the PPG-1 glycerin ether; PPG-9,2-Pyrrolidone-5-carboxylic acid and salt thereof such as glyceryl pca, sugared isomerate; SEACARE (available from Secma); sericin, Silk Amino Acids, acetyl group hyaluronate sodium; hyaluronate sodium; poly (sodium aspartate), polyglutamic acid sodium, sorbitol polyoxyethylene ether (sorbeth) 20; sorbitol polyoxyethylene ether 6; sugar and sugar alcohol and derivant such as glucose; mannose and polyglycereol sorbitol, trehalose, triglycerin; trimethylolpropane; three (methylol) aminomethane salt, yeast extract, and their mixture.

More preferably, be used for wetting agent of the present invention and be selected from: glycerol, urea, butanediol, Polyethylene Glycol and derivant thereof, and their mixture.Also more preferably, being used for wetting agent of the present invention is selected from: glycerol, urea and their mixture, particularly glycerol.Optional member

Can contain various optional components in the compositions among the present invention, these optional members are suitable for making the present composition to have more pleasant beauty treatment or beautify characteristic, and additional result of use perhaps is provided.These optional members commonly used are that those of ordinary skills are known.Comprising the various compositions that are applicable to cosmetics, as at " international cosmetics dictionary of CTFA and handbook (CTFA InternationalCosmetic Ingredient Dictionary and Handbook, the 7th edition, Wenninger and McEwen compile, (The Cosmetic, Toiletry, and Fragrance Association, Inc., Washington, those that can find D.C., 1997)).Below listed some non-limiting example in these optional members.Polar solvent

Can also contain polar solvent in the compositions of the present invention.Any polar solvent that is suitable for being used in the cosmetic composition all can be with in the present invention.But this polar solvent should have enough polarity, to impel the vesicle that forms among the present invention.The polar solvent that is preferred in the present composition is a water.

Preferably contain 10% to 90% in the compositions of the present invention, more preferably 20% to 80%, the polar solvent of 30% to 60% (weight) more preferably also.Emollient

Compositions camber preferred optional composition among the present invention is emollient (emollient).Slickness and flexibility that emollient is used for lubricated skin, promotes skin, prevention and alleviate xerosis cutis, and/or protection skin.Various suitable emollient are known, and they are all in the present invention available.The Cosmetics that Sagarin showed, Science and Technology has comprised the example of numerous materials that is suitable for use as emollient in (the 2nd edition, the 1st volume, 32-43 page or leaf (1972)).Preferred compositions of the present invention comprises greater than 1%, more preferably is at least 5%, also more preferably is at least the emollient of 10% (weight).

The emollient that preferably is applicable to this is selected from:

I) have and contain 7 straight or branched hydrocarbon approximately, as dodecane, squalane, vaseline, cholesterol and their derivant, Parleam, 2-Methylpentadecane and C to about 40 carbon atoms ₇-C ₄₀Isoparaffin (is C ₇-C ₄₀Branched-chain hydrocarbons).

Ii) C ₁-C ₃₀Carboxylic acid and C ₂-C ₃₀The C of dicarboxylic acids ₁-C ₃₀Alcohol ester, isononyl isononanoate for example, isopropyl myristate, propanoic acid myristin, isopropyl stearate, behenic acid docosane alcohol ester, maleic acid dioctyl ester, diisopropyl adipate and dilinoleic acid diisopropyl ester.

Iii) C ₁-C ₃₀The monoglyceride of carboxylic acid, two glyceride and triglyceride and ethoxylated derivative thereof.The polyethyleneglycol derivative of the glyceride that is suitable for comprises: PEG-20 Semen Armeniacae Amarum glyceride, PEG-60 Semen Armeniacae Amarum glyceride, PEG-11 American Avocado Tree glyceride, PEG-6 suffering/caprin, PEG-8 suffering/caprin, PEG-20 corn glyceride, PEG-60 corn glyceride, PEG-60 Radix Oenotherae erythrosepalae oil glyceride, PEG-7 glyceryl cocos nucifera oil ester, PEG-30 glyceryl cocos nucifera oil ester, PEG-40 glyceryl cocos nucifera oil ester, PEG-78 glyceryl cocos nucifera oil ester oil ester, PEG-80 glyceryl cocos nucifera oil ester, PEG-12 glyceryl dioleate, PEG-15 glyceryl isostearate, PEG-20 glyceryl isostearate, PEG-30 glyceryl isostearate, PEG-75 cocoa butter glyceride, PEG-20 hydrogenated palm oil glyceride, PEG-70 Fructus Mangifera Indicae glyceride, PEG-13 ermine YOUGAN grease, PEG-75 sal tree YOUGAN grease, PEG-10 olive oil glyceride, PEG-12 palm-kernel oil glyceride, PEG-45 palm-kernel oil glyceride, PEG-8 glyceryl laurate and PEG-30 glyceryl laurate.The mixture of the polyethyleneglycol derivative of glyceride also can be used for the present invention.

Iv) C ₁-C ₃₀The alkylidene diol ester of carboxylic acid, for example C ₁-C ₃₀The ethylene glycol ester of carboxylic acid and diester, and propylene glycol monoester and diester, for example diglycol stearate.

V) organopolysiloxane oil.Organopolysiloxane oil can be mixture volatile, nonvolatile or volatility and non-volatile polysiloxanes.Term used herein " nonvolatile " is meant and is liquid under environmental condition, and flash-point (under 1 atmospheric pressure) is more than or equal to those about 100 ℃ polysiloxanes.Term used herein " volatile " is meant all other polysiloxane oil.The organopolysiloxane oil that is suitable for can be selected from the various polysiloxanes of volatility and viscosity leap relative broad range.Preferred non-volatile polysiloxanes.The polysiloxanes that is suitable for is disclosed in United States Patent (USP) 5,069,897 (December was authorized on the 3rd in 1991).Be preferred for organopolysiloxane of the present invention and be selected from polydimethylsiloxane that poly-alkylsiloxane, alkyl replace, dimethiconol, poly-alkaryl siloxanes and composition thereof.More preferably being used for of the present invention is poly-alkylsiloxane and ring-type polymethyl siloxane (cyclomethicone).Polydimethylsiloxane preferably in the poly-alkylsiloxane.

Vi) vegetable oil and hydrogenated vegetable oil.The example of vegetable oil and hydrogenated vegetable oil comprises: the partial hydrogenation of the oil in safflower oil, Oleum Ricini, Oleum Cocois, Oleum Gossypii semen, pilchardine, palm-kernel oil, Petiolus Trachycarpi oil, Oleum Arachidis hypogaeae semen, soybean oil, rapeseed oil, Semen Lini oil, Testa oryzae oil, Oleum Pini, Oleum sesami, sunflower oil, above-mentioned source and perhydrogenate form, and their mixture.

Vii) animal oil, for example cod liver oil, lanoline and derivant thereof are as acetylated lanolin and lanolin fatty acid isopropyl ester.Preferred lanolin oil.

The viii) operable C that also has polypropylene glycol ₄-C ₂₀The C of alkyl ether, polypropylene glycol ₁-C ₂₀Carboxylate and two-C ₈-C ₃₀Alkyl ether, example comprise PPG-14 butyl ether, PPG-15 stearyl ether, dicaprylyl ether, dodecyl Octyl Ether and composition thereof.

Ix) polyol carboxylic acid ester.

X) mixture of mentioned component.

The emollient that is preferred in the present composition is selected from: dodecane, squalane, cholesterol and derivant thereof, 2-Methylpentadecane, isononyl isononanoate, vaseline, lanoline and derivant thereof, safflower oil, Oleum Ricini, Oleum Cocois, Oleum Gossypii semen, palm-kernel oil, Petiolus Trachycarpi oil, Oleum Arachidis hypogaeae semen, soybean oil, polyol carboxylic acid ester and their mixture.More preferably be used for emollient of the present invention and be selected from polyol carboxylic acid ester, vaseline and their mixture.

These esters are derived from sugar or polyol moiety and one or more carboxylic moiety.Depend on the sour and sugared of formation, these esters can be the liquid or solid form at ambient temperature.The example of liquid ester comprises: four oleic acid glucose esters, glucose four esters of soya fatty acid (unsaturated), mannose four esters of mixed soya fatty acid, oleic galactose four esters, linoleic arabinose four esters, xylose four linoleates, five oleic acid gala sugar esters, four oleic acid sorbitol esters, unsaturated soya fatty acid sorbitol six esters, the five oleic acid esters of xylitol, four oleic acid sucrose ester, five oleic acid sucrose ester, six oleic acid sucrose ester, seven oleic acid sucrose ester, eight oleic acid sucrose ester and composition thereof.The example of solid ester comprises: sorbitol six esters, carboxylate moiety wherein are that mol ratio is 1: 2 palm acid ester and an Arachidate; Raffinose octaester, carboxylate moiety wherein are that mol ratio is 1: 3 linoleate and a docosane acid esters; Maltose seven esters, wherein esterification carboxylic moiety are that mol ratio is 3: 4 sunflower oil fatty acid and a lignocerane acid esters; The octaester of sucrose, wherein esterification carboxylic moiety are that mol ratio is 2: 6 oleate and a docosane acid esters; And the octaester of sucrose, wherein esterification carboxylic moiety is that mol ratio is 1: 3: 4 laurate, linoleate and a docosane acid esters.Preferred solid material is an Olestra, and wherein esterification degree is 7-8, and fatty acid part wherein is C ₁₈Single-and/or two-unsaturated acids and behenic acid, wherein the mol ratio of unsaturated acids and behenic acid is 1: 7-3: 5.Particularly preferred sugar cube polyester is the octaester of sucrose, wherein contains 7 22 carbon fatty acid parts and about 1 oleic acid part in the molecule approximately.Other material comprises Oleum Gossypii semen or soya fatty acid sucrose ester.These esters materials also are disclosed in United States Patent (USP) 2,831,854; United States Patent (USP) 4,005,196 (Jandacek, on January 25th, 1977 authorized); United States Patent (USP) 4,005,195 (Jandacek, on January 25th, 1977 authorized), United States Patent (USP) 5,306,516 people such as (, on April 26th, 1994 authorized) Letton; United States Patent (USP) 5,306,515 (people such as Letton, on April 26th, 1994 authorized); United States Patent (USP) 5,305,514 (people such as Letton, on April 26th, 1994 authorized); United States Patent (USP) 4,797,300 (people such as Jandacek, on January 10th, 1989 authorized); United States Patent (USP) 3,963,699 (people such as Rizzi, on June 15th, 1976 authorized); United States Patent (USP) 4,518,772 (Volpenhein, on May 21st, 1985 authorized); And United States Patent (USP) 4,517,360 (Volpenhein, on May 21st, 1985 authorized).

Be applicable to that the polynary ester of polyol fatty acid of the present invention can be prepared by the whole bag of tricks known in the art.These methods comprise that the various catalyst of employing carry out ester exchange by polyhydric alcohol and methyl, ethyl or glycerin fatty acid ester; Adopt fat acyl chloride that polyhydric alcohol is carried out acylation; Adopt fatty acid anhydride that polyhydric alcohol is carried out acylation; And adopt fatty acid that polyhydric alcohol is carried out acylation.For example can be referring to United States Patent (USP) 2,831,854; United States Patent (USP) 4,005, the content described in 196 (Jandacek, on January 25th, 1977 authorized).

Particularly preferred material is the material of the poly-oleic acid sucrose ester of INCI called after.Other skin beneficiating ingredient

Can use other skin beneficiating ingredient in the inventive method compositions for use.The example that can be used for other skin beneficiating ingredient of the present composition comprises: (a) element-vitamine compound

Can contain element-vitamine compound, its precursor and derivant thereof in the present composition.These element-vitamine compounds can be native forms, also can be synthesized forms.The element-vitamine compound that is suitable for comprises: vitamin A (for example, beta-carotene, tretinoin, retinol, retinal compounds (retinoids), retinyl palmitate, propanoic acid retinol ester etc.), vitamin B (for example, nicotinic acid, nicotiamide, riboflavin, pantothenic acid etc.), vitamin C (for example, ascorbic acid etc.), vitamin D (for example, ergosterol, ergocalciferol, cholecalciferol etc.), vitamin E (for example, tocopherol acetate etc.) and vitamin K (for example, phytonadione, menadione, phthiocol etc.) chemical compound.The element-vitamine compound that is preferred in the compositions for use of the present invention is a vitamin B ₃Chemical compound.Vitamin B ₃Chemical compound is specially adapted to regulate skin, and related content is disclosed among the WO-A-97/39733.If use element-vitamine compound, then preferably comprise about 0.01% (weight) in the present composition to about 50% (weight), be more preferably 0.1% (weight) to about 10% (weight), also be more preferably the vitamin B of 0.5% (weight) to about 5% (weight) ₃Chemical compound.

Be used for term " vitamin B of the present invention ₃Chemical compound " be meant the chemical compound that is shown below:

Wherein R is-CONH ₂(being nicotiamide) ,-COOH (being nicotinic acid) or-CH ₂OH (being cigarette base alcohol (nicotinyl alcohol)); And derivant; And the salt of above-claimed cpd.

Said vitamin B ₃The example of the derivant of chemical compound comprises: nicotinate comprises the non-distensibility of blood vessel ester of nicotinic acid; Cigarette base alcohol ester, nicotinic acid N-oxide and the nicotinoyl amine n-oxide of cigarette base aminoacid, carboxylic acid.

Suitable vitamins B ₃Examples for compounds is well known in the art, and can be available from a plurality of sources, for example the Sigma chemical company (St.Louis, MO); ICN Biomedicines, Inc. (Irvin, CA) and the Aldrich chemical company (Milwaukee, WI).

Element-vitamine compound can be substantially adds with the form of pure product, or obtains form of extract and add to be separated through suitable physics and/or chemical method by natural origin (for example plant).(b) crease-resistant and anti-atrophoderma active component

The example that can be used for crease-resistant and anti-atrophoderma (anti-skin atrophy) active component in the present composition comprises: lactic acid and derivant thereof; Tretinoin and derivant thereof (for example cis with trans); Retinol; Retinyl ester; Nicotiamide; Salicylic acid and derivant thereof; The D of sulfur-bearing and L aminoacid and derivant and salt, particularly N-acetyl derivative, its preferred examples are N-acetyl group-L-cysteine; Thio-alcohol, for example, ethyl mercaptan; Hydroxy acid; Phytic acid; Thioctic acid; Lysophosphatidic acid, and decorticating agent (skin peel agent) (for example, phenols etc.), but be not limited only to these.(c) antimicrobial and antifungal activity composition

Can be used for the antimicrobial of the present composition and the example of antifungal activity composition comprises: Beta-lactam medicine, quinolones, ciprofloxacin, norfloxacin, tetracycline, erythromycin, amikacin, 2,4,4 '-three chloro-2 '-hydroxy diphenyl ether, 3,4,4 '-three chloro-carbanilides, phenyl phenol, phenoxypropanol, the phenoxy group isopropyl alcohol, doxycycline, capreomycin, chlohexidine, chlortetracycline, oxytetracycline, clindamycin, ethambutol, esomedina, metronidazole, penta oxygen benzene carbon amidine, gentamycin, kanamycin, lincomycin (lineomycin), methacycline, hexamethylenamine, minocycline (minocycline), neomycin, netilmicin, paromomycin, streptomycin, tobramycin, miconazole, quadracycline, erythromycin, erythromycin zinc, erythromycin propionate lauryl sulfate, erythromycin stearate, amikacin sulfate, doxycycline hydrochloride, capreomycin sulfate Capastat sulfate, chlorhexidine gluconate, chlorhexidine dihydrochloride, chlortetracycline hydrochloride, tetramycin hydrochloride, clindamycin hydrochloride, ebutol, the hydrochloric acid metronidazole, hydrochloric acid penta oxygen benzene carbon amidine, gentamycin sulfate, kanamycin sulfate, lincomycin hydrochloride (lineomycin), methacycline hydrochloride, methenamine hippu, mandelamine, minocycline hydrochloride, polygynax, netilmicin sulfate, paromomycin sulfate, streptomycin sulfate, tobramycin sulfate, the hydrochloric acid miconazole, amantadine hydrochloride (amanfadine hydrochloride), PK-Merz (Merz) (amanfadine sulfate), Octopirox, chlorxylone, nystatin, tolnaftate (tolnaftate), pyrithione zinc and clotrimazole.(d) sunscreen actives composition

Also can contain the sunscreen actives composition in the compositions of the present invention.Various sunscreen all can be used among the present invention.These sunscreen include organic compounds and salt and inorganic particulate material.Although without wishing to be bound by theory, believe that sunscreen can prevent to be subjected to ultraviolet radiation by one or more following mechanism protection skins, comprising: absorption, scattering and reflect UV radiation.The non-limiting example of these sunscreen is disclosed in: United States Patent (USP) 5,087,445 (people such as Haffey, on February 11st, 1992 authorized); United States Patent (USP) 5,073,372 (people such as Turner, December was authorized on the 17th in 1991); United States Patent (USP) 5,073,371 (people such as Turner, December was authorized on the 17th in 1991); United States Patent (USP) 5,160,731 (people such as Sabatelli, on November 3rd, 1992 authorized); United States Patent (USP) 5,138,089 (Sabatelli, on August 11st, 1992 authorized); United States Patent (USP) 5,041,282 (Sabatelli, on August 20th, 1991 authorized); United States Patent (USP) 4,999,186 (people such as Sabatelli, on March 12nd, 1991 authorized); United States Patent (USP) 4,937,370 (Sabatelli, authorize June 26 nineteen ninety); And people such as Segarin is in the described content of " cosmetic science and technology " (Cosmetics Science and Technology, the VIII chapter is below 189 pages).Preferred sunscreen is selected from: p-methoxycinnamic acid 2-Octyl Nitrite; ethylhexyl salicylate; octocrylene; the hydroxyl methoxy benzophenone; N; N-dimethylaminobenzoic acid 2-Octyl Nitrite; para-amino benzoic acid; 2-phenyl-benzimidazole-5-sulfonic acid; salicylic acid ester in the high Meng; the p-methoxycinnamic acid diethanolamine; 4; 4 '-methoxyl group-tert-butyl group dibenzoyl methane; 4-isopropyl diphenyl formyl methane; 3-(4-methyl benzal) Camphora; the 3-benzylidene camphor; 4-N; N-dimethylaminobenzoic acid and 2; the ester of 4-dihydroxy benzophenone; 4-N; the ester of N-dimethylaminobenzoic acid and 2-hydroxyl-4-(2-hydroxyl-oxethyl) benzophenone; 4-N; the ester of N-dimethylaminobenzoic acid and 4-hydroxy benzophenone acyl group methane; 4-N; the ester of N-dimethylaminobenzoic acid and 4-(2-hydroxyl-oxethyl) dibenzoyl methane; 4-N; N-two (2-ethylhexyl)-amino benzoic Acid and 2; the ester of 4-dihydroxy benzophenone; 4-N; the ester of N-two (2-ethylhexyl) amino benzoic Acid and 2-hydroxyl-4-(2-hydroxyl-oxethyl) benzophenone; 4-N; the ester of N-two (2-ethylhexyl) amino benzoic Acid and 4-hydroxy benzophenone acyl group methane; 4-N; the ester of N-two (2-ethylhexyl) amino benzoic Acid and 4-(2-hydroxyl-oxethyl) dibenzoyl methane; 4-N; N-(2-ethylhexyl) methylamino benzoic acid and 2; the ester of 4-dihydroxy benzophenone; 4-N; the ester of N-(2-ethylhexyl) methylamino benzoic acid and 2-hydroxyl-4-(2-hydroxyl-oxethyl) benzophenone; 4-N; the ester of N-(2-ethylhexyl) methylamino benzoic acid and 4-hydroxy benzophenone acyl group methane; 4-N, the ester of N-(2-ethylhexyl) methylamino benzoic acid and 4-(2-hydroxyl-oxethyl) dibenzoyl methane; titanium dioxide; zinc oxide; ferrum oxide and composition thereof.

The sunscreen that more preferably is used for the present composition is selected from: N; N-dimethyl-para-amino benzoic acid 2-Octyl Nitrite; p-methoxycinnamic acid 2-Octyl Nitrite; octocrylene; ethylhexyl salicylate; salicylic acid ester in the high Meng; para-amino benzoic acid; the hydroxyl methoxy benzophenone; 2-Phenylbenzimidazole-5-sulfonic acid; the p-methoxycinnamic acid diethanolamine; 4; 4 '-methoxyl group-tert-butyl group dibenzoyl methane; 4-isopropyl diphenyl formoxyl methane; 3-(4-methyl benzal) Camphora; the 3-benzylidene camphor; 4-N, the ester of N-(2-ethylhexyl) methylamino benzoic acid and 4-(2-hydroxyl-oxethyl) dibenzoyl methane; titanium dioxide; zinc oxide; ferrum oxide and composition thereof.

The definite consumption of the sunscreen that can use depends on selected sunscreen and the sun protection factor that will reach, and (Sun Protection Factor SPF) is worth and different.SPF often is used to weigh the photoprotection that sunscreen prevents to produce skin erythema.Referring to Federal Register, 43 volumes, No. 166,38206-38269 page or leaf, on August 25th, 1978.Thickening agent

Preferably contain thickening agent in the compositions among the present invention.Any thickening agent that is applicable to cosmetic composition all can be used for the present invention.Preferred thickening is selected from non-ionic water-soluble polymer, aliphatic alcohol and composition thereof.The non-ionic polymers that is suitable for comprises such water-soluble polymer, as cellulose ether (for example hydroxy butyl methyl cellulose, hydroxypropyl cellulose, hydroxypropyl emthylcellulose, ethylhydroxyethylcellulose, hydrophobically modified hydroxyethyl-cellulose and hydroxyethyl-cellulose), poly-(oxygen ethylene), polyvinyl alcohol, polyvinyl pyrrolidone, hydroxypropyl guar gum, amylose (amulose), ethoxy amylose (amylose), starch and starch derivatives.The aliphatic alcohol that is suitable for is the high-molecular weight nonvolatile primary alconol with following general formula:

RCH ₂OH

Wherein R is C _8-20Alkyl.They can be made by natural oil or fat, by with fatty acid-the COOH carboxyl reduction becomes the hydroxyl-functional base to obtain.The aliphatic alcohol that perhaps, can prepare identical or similar structures by conventional method known in the art.Suitable aliphatic alcohol comprises: tadenan, C ₉-C ₁₁Alcohol, C ₁₂-C ₁₃Alcohol, C ₁₂-C ₁₅Alcohol, C ₁₂-C ₁₆Alcohol, C ₁₄-C ₁₅Alcohol, capryl alcohol, spermaceti/stearyl alcohol, Cortex cocois radicis oleyl alcohol, decanol, different spermol, isooctadecanol, lauryl alcohol, oleyl alcohol, palm kernel alcohol, stearyl alcohol, spermol, tallow alcohol, tridecyl alcohol or myristyl alcohol, but be not to be only limited to these.Other optional member

Can contain various other optional components with in the methods of the invention compositions.These annexing ingredients should be pharmaceutically useful.By functional classification, be applicable to that the non-limiting example of the composition in the present composition comprises: abrasive material, absorbent, anti-acne active ingredient, anticaking agent, dandruff removing agent, antiperspirant, antioxidant, the antiviral activity composition, artificial suntan and promoter, bio-additive, bleach, bleach-activating, brightening agent, synergist, buffer agent, chelating agen, chemical addition agent, coloring agent, the beauty treatment composition, cleaning agent, the used for cosmetic astringent, the used for cosmetic antibacterial, modifier, deodorizer, the decortication active component, depilatory, medicinal astringent, dyestuff, transfection agents, enzyme, the external application analgesic agent, foaming agent, correctives, film former, perfume composition, anthelmintic, antifungus agent, on-steroidal anti-inflammatory activity composition, opacifier, oxidation dye, oxidant, the deinsectization composition, pH regulator agent such as citric acid, the pH buffer agent, active constituents of medicine, plasticizer, antiseptic, free radical scavenger, skin or hair or fingernail bleach, skin or hair or fingernail conditioner, skin or hair or fingernail penetration enhancer, stabilizing agent, surfactant, surface amendment, Reducing agent, the temperature inhibitor, viscosity modifier and heating agent are as the heating zeolite.What be applicable to this beautifies component (aesthetic components) as coloring agent, essential oil, skin healing agent.Other optional, materials that is applicable to this comprises: pigment.The pigment that is applicable to the present composition can be organic and/or inorganic constituents.In term pigment scope, also have less colored or the low gloss material, as the delustring finishing agent, and light scattering agent.The example of the pigment that is suitable for has ferrum oxide, acyl glutamic acid ferrum oxide, titanium dioxide, ultramarine, D﹠amp; C dyestuff, alkermes and composition thereof.Compound method

Compositions for use prepares in the mode that quaternary ammonium compound can form vesicle in preferred the inventive method.Also contain wetting agent in the preferred described vesicle.Preferably, also comprise emollient in the described vesicle.For guaranteeing the optimum performance feature, the preferred present composition is prepared by following steps:

(i) under the temperature that is higher than the quaternary ammonium congruent melting point, preferably also have polar solvent mixed mutually all or part of quaternary ammonium composition and wetting agent, water solublity skin care activity composition (if comprising);

(ii) randomly, with this mixture vigorous stirring;

(iii) in another independent container, prepare Emulsion as follows: be higher than under the temperature of quaternary ammonium compound fusing point with contain the oil phase of emollient, relevant thickening agent (if described thickening agent is oil-soluble) becomes phase-splitting to mix with remaining quaternary ammonium.Prepare water separately.Water, relevant thickening agent (if described thickening agent is water miscible) are heated to the temperature identical with oil phase with other water soluble ingredient.

(iv), under stirring condition, water and oil phase are merged then the about balance of temperature of the oil phase and the water of emulsion.

(v) when preparation Emulsion, the mixture of making in the step (i) is under agitation added in the above-mentioned Emulsion.

Embodiment

Following examples are used to further specify the embodiment preferred in the scope of the invention.Listed embodiment only is used to purpose of the present invention is described, is not to be used to limit the present invention, and under the situation that does not deviate from the spirit or scope of the present invention, there is multiple variation pattern in the present invention.Unless otherwise indicated, all the components is all with the weight percent meter of active component.

Embodiment	??1	??2	??3	??4	??5	??6	??7	??8	??9	??10	??11	??12	??13
																% (weight)
Quaternary ammonium composition (seeing note)	??3	??3	??3	??3	??3	??3	??3	??3	??3	??3	??3	??3	??3	??A
															Glycerol	??32	??32	??32	??32	??32	??32	??32	??-	??-	??-	??-	??-	??-	??A
Urea	??-	??-	??-	??-	??-	??-	??-	??22	??22	??22	??22	??22	??22	??A
															Vaseline	??-	??-	??10	??-	??12	??15	??-	??-	??-	??10	??-	??12	??15	??B

Lanoline 1	??-	??-	??-	??7.5	??5	??-	???15	??-	??-	??-	??10	??10	??-	??B
															The Coronet lanoline 1	??-	??-	??-	??-	??-	??-	????5	??-	??-	??-	??-	??-	??-	??B
Super sterol ester 1	??-	??-	??-	??-	??-	??-	????5	??-	??-	??-	??-	??-	??-	??B
															Sefa cotton oil acid esters	??21	??21	??12	??12	??-	??-	????-	??21	??21	??12	??12	??-	??-	??B
Polydimethylsiloxane 10 centistokes	??-	??0.5	??0.5	??0.5	??-	??0.5	??0.5	??0.5	??-	??-	??-	??0.5	??0.5	??B
															Polydimethylsiloxane 1000 centistokes	??-	??1.0	??1.0	??1.0	??-	??1.0	??1.0	??1.0	??-	??-	??-	??1.0	??1.0	??B
The ring-type polymethyl siloxane	??-	??2.5	??2.5	??2.5	??-	??2.5	??2.5	??2.5	??-	??-	??-	??2.5	??2.5	??B
															Florasun?PEG-10 2	??-	??2	??-	??2	??-	??3	??-	??1	??-	??-	??3	??-	??-	??B
Methyl parahydroxybenzoate	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??A
															Propyl p-hydroxybenzoate	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??B
The EDTA disodium	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??A
															Sodium benzoate	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??B
Nicotiamide	??5	??5	??3		??5	??5	??5	??3	??5			??5	??5	??A
															Pantothenylol	??3	??3	??1		??3	??3	??3	??1	??3			??3	??3	??A
Tocopherol acetate	??2	??2	??0.5		??2	??2	??2	??0.5	??2			??2	??2	??B
															Retinyl palmitate	??0.1	??-	??-	??-	??-	??-	??0.05	??-	??-	??0.1	??-	??-	??-	??B
Parsol?1789 3	??-	??1	??-	??1	??0.5	??-	??0.1	??-	??1	??-	??1	??-	??1	??B
															Parsol?MCX 3	??-	??5	??-	??5	??2.5	??-	??0.5	??-	??5	??-	??5	??-	??5	??B
Citric acid	??1	??0.5	??1	??0.5	??0.5	??1	??0.5	??1	??0.3	??0.75	??1	??1	??1	??A
															Salicylic acid	??-	??0.5	??-	??0.5	??0.5	??-	??0.5	??-	??0.7	??-	??-	??-	??-	??A
Triethanolamine	??0.1	??-	??-	??0.1	??0.1	??-	??-	??-	??0.1	??-	??-	??0.9	??0.5	??C
															Sodium hydroxide	??-	??-	??0.1	??0.1	??0.1	??-	??-	??0.1	??-	??0.1	??-	??-	??-	??C
Polyquaternary ammonium salt-10	??-		??-	??1.0		??-	??0.5	??-	??0.6	??-	??-	??-	??0.5	??B
															Polymer KG 30 4	??-	??0.7	??-		??0.7	??-		??-	??-	??0.8	??-	??-	??-	??B
Spice	??0.5	??0.5	??0.5	??0.5	??0.5	??-	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??E
															Spermol	??3	??-	??-	??-	??2.6	??-	??-	??2.2	??-	??2.2	??-	??2.5	??-	??C
Stearyl alcohol	??2	??-	??-	??-	??1.5	??-	??-	??3.2	??-	??1.1	??-	??1.6	??-	??C
															Spermaceti/stearyl alcohol	??-	??-	??4	??-	??0.4	??-	??-	??-	??3.4	??-	??-	??-	??3.4	??C

Tadenan	??2	???-	??2	??-	?-	??-	??-	?0.6	?-	?0.7	?-	??-	?-	??C
															Natrosol?330?Plus	??1	??-	??-	??-	?0.4	??-	??-	?0.7	?0.6	??-	?-	??0.5	?0.25	??C
Natrosol?250?HHR	??-	??-	??1	??-	?0.3	??-	??-	??-	?-	?1.2	?-	??-	?0.3	??C
															Jaguar?HP?105 5	??-	??1.2	??-	??-	?-	??-	??-	??-	?-	??-	?0.8	??-	?-	??D
Jaguar?C14S 5	??-	??-	??-	??1	?-	??-	??-	??-	?-	??-	?-	??-	?-	??D
															Jaguar?C13S 5	??-	??-	??-	??-	?-	??1.2	??-	??-	?-	??-	?-	??-	?-	??D
Xanthan gum	??-	??-	??-	??-	?-	??-	??2.0	??-	?-	??-	?-	??-	?-	??D
															Sodium chloride	??-	??-	??0.1	??-	?-	??-	??0.5	??0.2	?-	??0.3	?-	??-	?-	??A
Water	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	??A

Embodiment	??14	??15	??16	??17	??18	??19	??20	??21	??22	??23	??24	??25	??26
																% (weight)
Quaternary ammonium composition (seeing note)	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??A
															Glycerol	??32	??32	??32	??32	??32	??32	??32	??-	??-	??-	??-	??-	??-	??A
Urea	??-	??-	??-	??-	??-	???-	??-	??22	??22	??22	??22	??22	??22	??A
															Vaseline	??-	??-	??10	??-	??12	??15	??-	??-	??-	??10	??-	??12	??15	??B
Lanoline 1	??-	??-	??-	??7.5	??5	???-	??15	??-	??-	??-	??10	??10	??-	??B
															The Coronet lanoline 1	??-	??-	??-	??-	??-	???-	??5	??-	??-	??-	??-	??-	??-	??B
Super sterol ester 1	??-	??-	??-	??-	??-	???-	??5	??-	??-	??-	??-	??-	??-	??B
															Sefa cotton oil acid esters	??21	??21	??12	??12	??-	???-	???-	??21	??21	??12	??12	??-	??-	??B
Polydimethylsiloxane 10 centistokes	??-	??0.5	??0.5	??0.5	??-	??0.5	??0.5	??0.5	??-	??-	???-	??0.5	??0.5	??B
															Polydimethylsiloxane 1000 centistokes	??-	??1.0	??1.0	??1.0	??-	??1.0	??1.0	??1.0	??-	??-	??-	??1.0	??1.0	??B
Cyclopolymethyl siloxane	??-	??2.5	??2.5	??2.5	??-	??2.5	??2.5	??2.5	??-	??-	??-	??2.5	??2.5	??B
															Florasun?PEG-10 2	??-	??2	??-	??2	??-	??3	???-	??1	??-	??-	??3	???-	??-	??B
Methyl parahydroxybenzoate	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??A
															Propyl p-hydroxybenzoate	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??0.5	??B
The EDTA disodium	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??0.1	??A
															Sodium benzoate	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??0.3	??B

Nicotiamide	??5	??5	??3		??5	??5	??5	??3	??5			??5	??5	??A
															Pantothenylol	??3	??3	??1		??3	??3	??3	??1	??3			??3	??3	??A
Tocopherol acetate	??2	??2	??0.5		??2	??2	??2	??0.5	??2			??2	??2	??B
															Retinyl palmitate	??0.1	??-	??-	??-	??-	??-	??0.05	??-	??-	??-	????-	??-	??0.15	??B
Parsol?1789 3	??-	??1	??-	??1	??0.5	??-	??0.1	??-	??1	??-	????1	??-	??1	??B
															Parsol?MCX 3	??-	??5	??-	??5	??2.5	??-	??0.5	??-	??5	??-	????5	??-	??5	??B
Citric acid	??1	?0.5	??1	??0.5	??0.5	??1	??0.5	??1	??0.3	??0.75	????1	??1	??1	??A
															Salicylic acid	??-	?0.5	??-	??0.5	??0.5	??-	??0.5	??-	??0.7	??-	????-	??-	??-	??A
Triethanolamine	??0.1	??-	??-	??0.1	??0.1	??-	??-	??-	??0.1	??-	????-	??0.9	??0.5	??C
															Sodium hydroxide	??-	??-	??0.1	??0.1	??0.1	??-	??-	??0.1	??-	??0.1	????-	???-	??-	??C
Polyquaternary ammonium salt-10	??-	??-	??-	??1.0	??-	??-	??0.5	??-	??0.6	??-	????-	???-	??0.5	??B
															Polymer KG 30 4	??-	??0.7	??-	??-	??0.7	??-	??-	??-	??-	??0.8	????-	???-	??-	??B
Spice	??0.5	??0.5	??0.5	??0.5	??0.5	??-	??0.5	??0.5	??0.5	??0.5	???0.5	???0.5	??0.5	??E
															Spermol	??3	??-	??-	??-	??2.6	??-	??-	??2.2	??-	??2.2	???-	???2.5	??-	??C
Stearyl alcohol	??2	??-	??-	??-	??1.5	??-	??-	??3.2	??-	??1.1	???-	???1.6	??-	??C
															Spermaceti/stearyl alcohol	??-	??-	??4	??-	??0.4	??-	??-	??-	??3.4	??-	???-	???-	??3.4	??c
Tadenan	??2	??-	??2	??-	??-	??-	??-	??0.6	??-	??0.7	???-	???-	??-	??C
															Natrosol?330?Plus	??1	??-	??-	??-	??0.4	??-	??-	??0.7	??0.6	??-	???-	???0.5	??0.25	??C
Natrosol?250?HHR	??-	??-	??1	??-	??0.3	??-	??-	??-	??-	??1.2	???-	???-	??0.3	??C
															Jaguar?HP?105 5	??-	??1.2	??-	??-	??-	??-	??-	??-	??-	??-	???0.8	???-	??-	??D
Jaguar?C14S 5	??-	??-	??-	??1	??-	??-	??-	??-	??-	??-	???-	???-	??-	??D
															Jaguar?C13S 5	??-	??-	??-	??-	??-	??1.2	??-	??-	??-	??-	???-	???-	??-	??D
Xanthan gum	??-	??-	??-	??-	??-	??-	??2.0	??-	??-	??-	???-	???-	??-	??D
															Sodium chloride	??-	??-	??0.1	??-	??-	??-	??0.5	??0.2	??-	??0.3	???-	???-	??-	??A
Water	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	??A

Embodiment	27	?28	?29	?30	?31	?32	?33	?34	?35	?36	?37	?38	?39	?40	?41
																		% (weight)
Quaternary ammonium composition (seeing note)	??3	??3	??3	??3	??3	??3	??3	??3	??3	??3	??3	??3	??3	??3	??3	A

Glycerol	??15	??16	??22	??9	??8	??9	??-	??32	??32	??32	??32	??32	??32	??32	??32	A
																	Propylene glycol	??-	??16	??-	??-	??-	??5	??12	??-	??-	??-	??-	??-	??-	??-	??-	A
Butanediol	??-	??-	??8	??8	??-	??8	??12	??-	??-	??-	??-	??-	??-	??-	??-	A
																	Urea	??-	??-	??-	??12	??-	??2	??9	??-	??-	??-	??-	??-	??-	??-	??-	B
Vaseline	??-	??-	??10	??-	??12	??15	??-	??-	??4	?7.5	??-	??12	??5	??-	??6	B
																	Lanoline 1	??-	??-	??-	?7.5	?7.5	??-	?15	??-	?3.5	??-	??3	??-	??-	??-	??-	B
The Coronet lanoline 1	??-	??-	??-	??-	??-	??-	??-	??-	??7	??-	?6.7	??-	??-	??6	??-	B
																	Super sterol ester 1	??-	??-	??-	??-	??-	??-	??-	??-	?3.5	??-	?6.5	??-	??3	??6	??3	B
2-Methylpentadecane	??-	??-	??-	??-	??-	??-	??-	??-	??-	??5	??-	??3	??-	??-	??3	B
																	Isononyl isononanoate	??-	??-	??-	??-	??-	??-	??-	??-	??-	??3	??-	??5	??-	??-	??-	B
Sefa cotton oil acid esters	??21	??21	??12	??12	??-	??-	??-	??13	??-	??8	??-	??-	??8	??12	??10	B
																	Sefa docosane acid esters	??-	??-	??-	??-	??-	??-	??-	??9	??-	??-	??3	??-	??5	??-	??-	B
Polydimethylsiloxane 10 centistokes	??-	?0.5	?0.5	?0.5	??-	?0.5	?0.5	?0.5	??-	??-	??-	?0.5	?0.5	??-	??-	B
																	Polydimethylsiloxane 1000 centistokes	??-	?1.0	?1.0	?1.0	??-	?1.0	?1.0	?1.0	??-	??-	??-	?1.0	?1.0	??-	??-	B
Cyclopolymethyl siloxane	??-	?2.5	?2.5	?2.5	??-	?2.5	?2.5	?2.5	??-	??-	??-	?2.5	?2.5	??-	??-	B
																	Florasun?PEG-10 2	??-	?2	??-	?2	??-	?3	?-	??1	??-	??-	??3	??-	??-	?2.5	??-	B
Methyl parahydroxybenzoate	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	A
																	Propyl p-hydroxybenzoate	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	B
The EDTA disodium	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	A
																	Sodium benzoate	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	B
Nicotiamide	?3	?5	?5	??-	??-	??5	??5	??5	??3	??3	??-	??5	??5	??5	??3	A
																	Pantothenylol	?1	?3	?3	??-	??-	??3	??3	??3	??1	??1	??-	??3	??3	??3	??1	A
Tocopherol acetate	?0.5	?2	?2	??-	??-	??2	??2	??2	?0.5	?0.5	??-	??2	??2	??2	?0.5	B
																	Retinyl palmitate	??-	??-	??-	?0.1	??-	?0.05	??-	??-	?0.1	??-	??-	??-	??-	??-	??-	B
Parsol?1789 3	??-	?1	??-	?1	?0.5	??-	??1	??-	??1	??-	??1	??-	?0.1	??1	??-	B
																	Parsol?MCX 3	??-	?5	??-	?5	?2.5	??-	??5	??-	??5	??-	??5	??-	?0.5	??5	??-	B
Citric acid	??1	?0.5	?1	?0.5	?0.5	??1	?0.5	??1	?0.3	?0.75	??1	??1	??1	??1	??-	A
																	Salicylic acid	??-	?0.5	??-	?0.5	?0.5	??-	?0.5	??-	?0.7	??-	??-	??-	??-	??-	?0.5	A

Triethanolamine	?0.1	??-	??-	?0.1	?0.1	??-	???-	?-	?0.1	??-	??-	?0.9	?0.5	??-	??-	C
																	Sodium hydroxide	??-	??-	?0.1	?0.1	?0.1	??-	???-	?0.1	??-	?0.1	??-	??-	??-	??-	?0.6	C
Polyquaternary ammonium salt-10	??-	??-	??-	?1.0	?-	??-	?0.5	??-	?0.6	??-	??-	??-	?0.5	?1.0	??-	B
																	Polymer KG 30 4	??-	?0.7	??-	??-	?0.7	??-	???-	??-	??-	?0.8	??-	??-	??-	??-	?0.8	B
Spice	?0.5	?0.5	?0.5	?0.5	?0.5	??-	?0.5	?0.5	?0.5	?0.5	?0.5	??0.5	?0.5	?0.5	?0.5	E
																	Spermol	??3	??-	??-	??-	?2.6	??-	??-	?2.2	??-	?2.2	??-	??2.5	??-	??-	?3.2	C
Stearyl alcohol	??2	??-	??-	??-	?1.5	???-	??-	?3.2	??-	?1.1	??-	??1.6	??-	??-	?2.6	C
																	Spermaceti/stearyl alcohol	??-	??-	??4	????-	?0.4	??-	??-	??-	?3.4	??-	??-	??-	?3.4	??-	??-	C
Tadenan	??2	??-	??2	????-	??-	??-	??-	?0.6	??-	?0.7	??-	??-	??-	??-	?0.2	C
																	Natrosol?330?Plus	??1	??-	??-	????-	?0.4	??-	??-	?0.7	?0.6	??-	??-	??0.5	?0.25	??-	?0.6	C
Natrosol?250?HHR	??-	??-	??1	????-	?0.3	??-	??-	??-	??-	?1.2	??-	??-	?0.3	??-	??-	C
																	Jaguar?HP?105 5	??-	?1.2	??-	???-	??-	??-	??-	??-	??-	??-	?0.8	??-	??-	??-	??-	D
Jaguar?C14S 5	??-	??-	??-	????1	??-	??-	??-	??-	??-	??-	??-	??-	??-	??-	??-	D
																	Jaguar?C13S 5	??-	?-	??-	????-	??-	1.2	??-	??-	??-	??-	??-	??-	??-	?0.8	??-	D
Xanthan gum	??-	?-	??-	????-	??-	?-	?3.0	??-	??-	??-	??-	??-	??-	??-	??-	D
																	Sodium chloride	??-	?-	0.1	????-	??-	??-	?0.5	?0.2	??-	?0.3	??-	??-	??-	?0.2	?0.1	A
Water	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	A

Embodiment	42	?43	?44	?45	?46	?47	?48	?49	?50	?51	?52	?53	?54	?55	?56
																		% (weight)
Quaternary ammonium composition (seeing note)	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	??8	A
																	Glycerol	??15	??16	??22	??9	??8	??9	??-	??32	??32	??32	??32	??32	??32	??32	??32	A
Propylene glycol	??-	??16		??-	??-	??5	??12	??-	???-	??-	??-	??-	??-	??-	??-	A
																	Butanediol	??-	??-	??8	??8	??-	??8	??12	??-	???-	??-	??-	??-	??-	??-	??-	A
Urea	??-	??-	??-	??12	??-	??2	??9	??-	???-	??-	??-	??-	??-	??-	?-	B
																	Vaseline	??-	??-	??10	??-	??12	??15	??-	??-	??4	?7.5	??-	?12	?5	??-	?6	B
Lanoline 1	??-	??-	??-	??7.5	??7.5	???-	?15	??-	?3.5	??-	??3	??-	??-	??-	?-	B
																	The Coronet lanoline 1	??-	??-	??-	??-	??-	???-	??-	??-	??7	??-	?6.7	??-	??-	??6	??-	B
Super sterol ester 1	??-	??-	??-	??-	??-	???-	??-	??-	?3.5	??-	?6.5	??-	??3	??6	??3	B

2-Methylpentadecane	??-	??-	??-	??-	???-	??-	??-	??-	??-	??5	??-	??3	??-	??-	??3	B
																	Isononyl isononanoate	??-	??-	??-	??-	???-	??-	??-	??-	??-	??3	??-	??5	??-	??-	??-	B
Sefa cotton oil acid esters	??21	??21	??12	??12	???-	??-	??-	??13	??-	??8	??-	??-	??8	??12	??10	B
																	Sefa docosane acid esters	??-	??-	??-	??-	???-	??-	??-	??9	??-	??-	??3	??-	??5	??-	??-	B
Polydimethylsiloxane 10 centistokes	??-	?0.5	?0.5	?0.5	???-	?0.5	?0.5	?0.5	??-	??-	??-	?0.5	?0.5	??-	??-	B
																	Polydimethylsiloxane 1000 centistokes	??-	?1.0	?1.0	?1.0	???-	?1.0	?1.0	?1.0	??-	??-	??-	?1.0	?1.0	??-	??-	B
The ring-type polymethyl siloxane	??-	?2.5	?2.5	?2.5	???-	?2.5	?2.5	?2.5	??-	??-	??-	?2.5	?2.5	??-	??-	B
																	Florasun?PEG-10 2	??-	??2	??-	??2	???-	??3	??-	??1	??-	??-	??3	??-	??-	?2.5	??-	B
Methyl parahydroxybenzoate	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	??0.5	A
																	Propyl p-hydroxybenzoate	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	??0.5	B
The EDTA disodium	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	?0.1	??0.1	A
																	Sodium benzoate	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	?0.3	??0.3	B
Nicotiamide	??3	??5	??5	??-	??-	??5	??5	??5	??3	??3	??-	??5	??5	??5	??3	A
																	Pantothenylol	??1	??3	??3	??-	??-	??3	??3	??3	??1	??1	??-	??3	??3	??3	??1	A
Tocopherol acetate	?0.5	??2	??2	??-	??-	??2	??2	??2	?0.5	?0.5	??-	??2	??2	??2	??0.5	B
																	Retinyl palmitate	??-	??-	??-	?0.1	??-	?0.05	??-	??-	?0.1	??-	??-	??-	??-	??-	??-	B
Parsol?1789 3	??-	??1	??-	??1	?0.5	??-	??1	??-	??1	??-	??1	??-	?0.1	??1	??-	B
																	Parsol?MCX 3	??-	??5	??-	??5	?2.5	??-	??5	??-	??5	??-	??5	??-	?0.5	??5	??-	B
Citric acid	??1	?0.5	??1	?0.5	?0.5	??1	?0.5	??1	?0.3	?0.75	??1	??1	??1	??1	??-	A
																	Salicylic acid	??-	?0.5	??-	?0.5	?0.5	??-	?0.5	??-	?0.7	??-	??-	??-	??-	??-	??0.5	A
Triethanolamine	?0.1	??-	??-	?0.1	?0.1	??-	??-	??-	?0.1	??-	??-	?0.9	?0.5	??-	??-	C
																	Sodium hydroxide	??-	??-	??0.1	?0.1	?0.1	??-	??-	?0.1	??-	?0.1	??-	??-	??-	??-	??0.6	C
Polyquaternary ammonium salt-10	??-	?-	??-	?1.0	??-	??-	?0.5	??-	?0.6	??-	??-	??-	?0.5	?1.0	??-	B
																	Polymer KG 30 4	??-	?0.7	??-	??-	?0.7	??-	??-	??-	??-	?0.8	??-	??-	??-	??-	??0.8	B
Spice	?0.5	?0.5	??0.5	?0.5	?0.5	??-	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	?0.5	??0.5	E
																	Spermol	??3	??-	??-	??-	?2.6	??-	??-	?2.2	??-	?2.2	??-	?2.5	??-	??-	??3.2	C
Stearyl alcohol	??2	??-	??-	??-	?1.5	??-	??-	?3.2	??-	?1.1	??-	?1.6	??-	??-	??2.6	C
																	Spermaceti/stearyl alcohol	??-	??-	??4	??-	?0.4	??-	??-	??-	?3.4	??-	??-	??-	?3.4	??-	??-	C

Tadenan	???2	-	??2	???-	??-	??-	??-	?0.6	?-	?0.7	??-	?-	???-	??-	??0.2	C
																	Natrosol?330?Plus	???1	-	??-	???-	??0.4	??-	??-	?0.7	?0.6	?-	??-	?0.5	??0.25	??-	??0.6	C
Natrosol?250?HHR	???-	-	??1	???-	??0.3	??-	??-	?-	??-	?1.2	??-	?-	??0.3	??-	??-	C
																	Jaguar?HP?105 5	???-	1.2	??-	???-	??-	??-	??-	?-	??-	?-	??0.8	?-	???-	??-	??-	D
Jaguar?C14S 5	???-	-	??-	???1	??-	??-	??-	?-	??-	?-	??-	?-	???-	??-	??-	D
																	Jaguar?C13S 5	???-	-	??-	???-	??-	??1.2	??-	?-	??-	?-	??-	?-	???-	??0.8	??-	D
Xanthan gum	???-	-	??-	???-	??-	??-	??3.0	?-	??-	?-	??-	?-	???-	??-	??-	D
																	Sodium chloride	???-	-	??0.1	???-	??-	??-	??0.5	?0.2	??-	?0.3	??-	?-	???-	??0.2	??0.1	A
Water	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	In right amount	A

1; Derive from Croda

2: derive from Floratech, AZ, USA

3: derive from Hoffman La Roche, NJ, USA

4: derive from Amerchol, NJ, USA

5: derive from Rhodia, NJ, USA note

● embodiment 1,4, and in 7,9,17,20,22,24,28,36,38,47,49,53,56, quaternary ammonium compound is adopted

Be VARISOFT TA100, by Goldschmidt supply, commodity are called Varisoft

TA100。

● embodiment 2,3,5,6,8,10,15,16,18,19,21,23,26,27,31,33,34,35,37,

In 41,45,46,48,50,51,52,54,55, that quaternary ammonium compound adopts is N, N-two (low erucic acids

Colza acyl group-oxygen-ethyl)-and the N-methyl, N-(2-ethoxy) methylsulfuric acid ammonium is by Goldschmidt

Supply, commodity are called Rewoquat V3620.

● among the embodiment 11, that quaternary ammonium compound adopts is N, N-two (canola acyl group-oxygen-second

Base)-and the N-methyl, N-(2-ethoxy) methylsulfuric acid ammonium, by the Goldschmidt supply, commodity are by name

Rewoquat?WE18

● among the embodiment 12, that quaternary ammonium compound adopts is N, N-two (canola acyl group-oxygen-second

Base)-and the N-methyl, N-(2-ethoxy) ammonium chloride, by the Goldschmidt supply, exploitation material (WE25)

● among the embodiment 13, that quaternary ammonium compound adopts is two (h-tallow base acylamino-the ethyl) (2-of methyl

Ethoxy) methylsulfuric acid ammonium, by the Goldschmidt supply, commodity are called Varisoft 110.

● among the embodiment 14, what quaternary ammonium compound adopted is methyl two (Adeps Bovis seu Bubali acylamino-ethyl) (2-ethoxy)

The methylsulfuric acid ammonium, by the Goldschmidt supply, commodity are called Varisoft 222.

● among the embodiment 25, what quaternary ammonium compound adopted is methyl isophthalic acid-Adeps Bovis seu Bubali acyl ethyl-2-Adeps Bovis seu Bubali imidazoline,

By the Goldschmidt supply, the exploitation material

● among the embodiment 29, what quaternary ammonium compound adopted is methyl isophthalic acid-Adeps Bovis seu Bubali acylamino-ethyl-2-Adeps Bovis seu Bubali miaow

The azoles quinoline, by the Goldschmidt supply, the exploitation material

● among the embodiment 30, what quaternary ammonium compound adopted is methyl isophthalic acid-Adeps Bovis seu Bubali acyl ethyl-2-Adeps Bovis seu Bubali imidazoline

Methylsulfate, by the Goldschmidt supply,

● among the embodiment 32, what quaternary ammonium compound adopted is methyl isophthalic acid-Adeps Bovis seu Bubali acylamino-ethyl-2-Adeps Bovis seu Bubali miaow

Azoles quinoline Methylsulfate, by the Goldschrnidt supply, commodity are called Varisoft 475, Varisoft

445

● among the embodiment 39, that quaternary ammonium compound adopts is N, N-dimethyl-N-(the canola acyl group-

Oxo-ethyl)-and N-(canola base acylamino-ethyl) amine, supply by Kao

● among the embodiment 40, that quaternary ammonium compound adopts is N, N-dimethyl-N-(the canola acyl group-

Oxygen-ethyl)-and N-(canola base acylamino-ethyl) methylsulfuric acid ammonium, supply by Kao

● among the embodiment 42, that quaternary ammonium compound adopts is N, N '-two (2-Adeps Bovis seu Bubali acyl group oxygen ethyl)-N, and N,

N ', N '-tetramethylene dichloride diammonium is disclosed in United States Patent (USP) 4728337, United States Patent (USP)

4721512, in the United States Patent (USP) 4906413, from Ciba-Geigy company

● among the embodiment 43, that quaternary ammonium compound adopts is N, N '-two (2-canola acyl group oxygen second

Base)-and N, N '-dimethyl-N, N '-(2-ethoxy)-1,6-hexane methylsulfuric acid diammonium is disclosed in

Among patent EP 0503155 A1 and EP 0803498 of Goldschmidt-Witco.

● among the embodiment 44, what quaternary ammonium compound adopted is by fatty acid, two functional groups (or multi-functional base)

Acid and triethanolamine react, then through quaternized dimerization that obtains and oligomeric esters quaternary ammonium compound,

Be disclosed in WO 98/49132 (Kao) and the United States Patent (USP) 5,880,289 (Henkel).Method is used to comprise the embodiment of component C:

1. pre-composition 1: each component under the condition that is higher than selected quaternary ammonium compound conversion temperature in the mixed A group, the quaternary ammonium compound and the water that keep scheduled volume do not add.Violent mixed this pre-composition.

2. pre-composition 2: remaining quaternary ammonium compound and water in each component in B and the C group and the above pre-composition 1 is mixed.Be heated to more than the fusing point of quaternary ammonium compound and oils.

3. pre-composition 1 and 2 is mixed, and be cooled to 40 ℃, stir adding essence.Be used to comprise the embodiment of component D:

1. pre-composition 1: each component under the condition that is higher than selected quaternary ammonium compound conversion temperature in the mixed A group, the water that keeps scheduled volume does not add.Violent mixed this pre-composition.

2. pre-composition 2: under agitation, that remaining water in component in the D group and the above pre-composition 1 is mixed.

With pre-composition 1 and 2 and B and E group in each component mixed.Vigorous stirring.

Embodiment

1. above-mentioned prescription 1-56 can be used for skin, rinsing then, the skin care of fine ground of result.

2. above-mentioned prescription 1-56 can be used for through comprising surfactant cleaning compositions skin.After washing the surfactant base product off, product is directly used on the moist skin.Eccysis compositions then.This trickle skin injury that can cause the product that contains surfactant works the effect of moistening.

3. the part that above-mentioned prescription 1-56 can be used as in the conventional program is applied, and therefore the present composition should be used for moist skin, and answer rinsing skin, and used this product in the same manner in 48 hours.But its skin care as a result makes it avoid containing the damage of the product of surfactant.

4. above-mentioned prescription 1-56 can be used for problematic dry skin position before wet skin.After the short time, wettable skin, and use surfactant washing skin.Use above-mentioned composition, clean then, the result smooth skin zone of can being strengthened thereafter.This " pre-nursing procedure " is effective especially to very dried skin, also can only be used to increase the effect of product.

5. above-mentioned prescription 1-56 can be used for problematic dry skin position before wet skin.After the short time, but rinsing skin.Use above-mentioned composition, clean then, the result smooth skin zone of can being strengthened thereafter.This " pre-nursing procedure " is effective especially to very dried skin, also can only be used to increase the effect of product.

6. above-mentioned prescription 1-56 can be used for moist skin in the program of shaving.Before shaving, product is used on the moist skin, replaced common shaving foam to be applied.Post rinse skin shaves.The result can be in the back skin care of shaving.

7. above-mentioned prescription 1-56 can use in the program of shaving.After shaving, product is applied on the skin, then rinsing skin.The result can make the skin after shaving more smooth and moist.

8. above-mentioned prescription 1-56 can use after swimming.Should rinse water chloride on the skin earlier before the application product.After the application, rinsing skin.Like this can skin care, and reduce the damage of chlorine to skin.

The skin effect that the method for addressing in the foregoing description can provide, as good moist effect, good hydration, good skin usability, good skin softness and/or good skin smoothness, and unfavorable effect such as greasy, sticky property or cohesiveness are low.

Claims (10)

1. the beauty method of nursing skin, this method comprises:

(i) on skin, use the compositions that comprises following compositions:

(a) at least a quaternary ammonium composition;

(b) wetting agent; And

(ii) rinsing skin.

2. the process of claim 1 wherein to comprise greater than 1% (weight) in the described compositions, preferably be at least the quaternary ammonium composition of 2% (weight).

3. claim 1 or 2 method comprise in the wherein said compositions greater than 4% (weight), are preferably greater than 5% (weight), more preferably are at least the wetting agent of 10% (weight).

4. the described method of arbitrary claim during aforesaid right requires comprises vesicle in the wherein said compositions, comprises quaternary ammonium composition and wetting agent in the described vesicle.

5. the described method of arbitrary claim during aforesaid right requires, this method comprises:

(i) on dry skin, use the compositions that comprises following compositions:

(a) at least a quaternary ammonium composition;

(b) wetting agent; And

(ii) rinsing skin.

6. the described method of arbitrary claim during aforesaid right requires, this method comprises:

(i) on dry skin, use the compositions that comprises at least a quaternary ammonium composition and wetting agent;

(ii) rinsing skin under shower;

(iii) use described compositions once more; And

(iv) rinsing once more.

7. the described method of arbitrary claim during aforesaid right requires comprises the wetting agent that is selected from glycerol, urea, butanediol, Polyethylene Glycol and derivant thereof and their mixture in the wherein said compositions.

8. the described method of arbitrary claim during aforesaid right requires, wherein the quaternary ammonium composition be easy to biodegradable.

9. the described method of arbitrary claim during aforesaid right requires, this method comprises:

(i) on skin, use the compositions that comprises following compositions:

(a) at least a quaternary ammonium compound;

(b) wetting agent; With

(ii) rinsing skin;

(iii) repeating step (i) and (ii) in 48 hours.

10. the described method of arbitrary claim during aforesaid right requires, this method comprises:

(i) adopt the cleaning compositions skin that contains surfactant;

(ii) rinsing skin;

The compositions that (iii) will contain at least a quaternary ammonium composition and wetting agent is used for moist skin;

(iv) rinsing skin.