CN1337944A - 作为TACE抑制剂的炔β－氨磺酰和次膦酸酰胺异羟肟酸 - Google Patents

作为TACE抑制剂的炔β－氨磺酰和次膦酸酰胺异羟肟酸 Download PDF

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Publication number: CN1337944A
Authority: CN; China
Prior art keywords: carbon atom; phenyl; unit; heteroatoms; heteroaryl
Prior art date: 1999-01-27
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.): Pending

Application number

CN00803031A

Other languages

English (en)

Chinese (zh)

Inventor

J·I·莱文

J·M·陈

A·萨斯科

Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)

Wyeth Holdings LLC

Original Assignee

American Cyanamid Co

Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)

1999-01-27

Filing date

2000-01-27

Publication date

2002-02-27

2000-01-27 Application filed by American Cyanamid Co filed Critical American Cyanamid Co

2002-02-27 Publication of CN1337944A publication Critical patent/CN1337944A/zh

Status Pending legal-status Critical Current

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Classifications

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- C07C311/22—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound oxygen atoms
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- C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
- C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
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- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
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CN00803031A 1999-01-27 2000-01-27 作为TACE抑制剂的炔β－氨磺酰和次膦酸酰胺异羟肟酸 Pending CN1337944A (zh)

Applications Claiming Priority (2)

Application Number	Priority Date	Filing Date	Title
US23908399A	1999-01-27	1999-01-27
US09/239,083		1999-01-27

Publications (1)

Publication Number	Publication Date
CN1337944A true CN1337944A (zh)	2002-02-27

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ID=22900530

Family Applications (1)

Application Number	Title	Priority Date	Filing Date
CN00803031A Pending CN1337944A (zh)	1999-01-27	2000-01-27	作为TACE抑制剂的炔β－氨磺酰和次膦酸酰胺异羟肟酸

Country Status (16)

Country	Link
EP (1)	EP1147078A1 (ja)
JP (1)	JP2002535383A (ja)
KR (1)	KR20010089617A (ja)
CN (1)	CN1337944A (ja)
AR (1)	AR035478A1 (ja)
AU (1)	AU769410B2 (ja)
BR (1)	BR0007754A (ja)
CA (1)	CA2356345A1 (ja)
CZ (1)	CZ20012709A3 (ja)
EA (1)	EA200100808A1 (ja)
HU (1)	HUP0200605A3 (ja)
IL (1)	IL144321A0 (ja)
NO (1)	NO20013639D0 (ja)
NZ (1)	NZ512025A (ja)
WO (1)	WO2000044711A1 (ja)
ZA (1)	ZA200104508B (ja)

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CN102471260A (zh) *	2009-06-30	2012-05-23	盖尔德马研究及发展公司	新型苯磺酰胺化合物、其合成方法及其在药品以及美容用品中的用途

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US7199155B2 (en)	2002-12-23	2007-04-03	Wyeth Holdings Corporation	Acetylenic aryl sulfonate hydroxamic acid TACE and matrix metalloproteinase inhibitors
ATE449760T1 (de)	2004-03-22	2009-12-15	Southern Res Inst	Nichtpeptidinhibitoren von matrixmetalloproteinasen
FR2950057B1 (fr) *	2009-09-17	2011-08-26	Galderma Res & Dev	Nouveaux composes benzene-carboxylamides, leur procede de synthese et leur utilisation en medecine ainsi qu'en cosmetique
BR112021006407A8 (pt)	2018-10-04	2022-12-06	Inst Nat Sante Rech Med	uso de inibidores do egfr para ceratodermas

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US5514716A (en) *	1994-02-25	1996-05-07	Sterling Winthrop, Inc.	Hydroxamic acid and carboxylic acid derivatives, process for their preparation and use thereof
HRP970245B1 (en) *	1996-05-15	2002-06-30	Bayer Ag	Biaryl acetilenes as matrix metalloprotease inhibitors
IL129147A0 (en) *	1996-10-16	2000-02-17	American Cyanamid Co	The preparation and use of ortho-sulfonamide aryl hydroxamic acids as matrix metalloproteinase and tace inhibitors
US5977408A (en) *	1996-10-16	1999-11-02	American Cyanamid Company	Preparation and use of β-sulfonamido hydroxamic acids as matrix metalloproteinase and TACE inhibitors
ES2200335T3 (es) *	1997-10-06	2004-03-01	Wyeth Holdings Corporation	Preparacion y utilizacion de acidos orto-sulfonamido(heteroarilo biciclico)hidroxamicos como inhibidores de las metaloproteinasas matriz y del tace.

2000
- 2000-01-26 AR ARP000100325A patent/AR035478A1/es not_active Application Discontinuation
- 2000-01-27 KR KR1020017009153A patent/KR20010089617A/ko not_active Application Discontinuation
- 2000-01-27 EA EA200100808A patent/EA200100808A1/ru unknown
- 2000-01-27 JP JP2000595968A patent/JP2002535383A/ja active Pending
- 2000-01-27 BR BR0007754-2A patent/BR0007754A/pt not_active IP Right Cessation
- 2000-01-27 NZ NZ512025A patent/NZ512025A/en unknown
- 2000-01-27 WO PCT/US2000/001865 patent/WO2000044711A1/en not_active Application Discontinuation
- 2000-01-27 IL IL14432100A patent/IL144321A0/xx unknown
- 2000-01-27 AU AU26306/00A patent/AU769410B2/en not_active Ceased
- 2000-01-27 CA CA002356345A patent/CA2356345A1/en not_active Abandoned
- 2000-01-27 CZ CZ20012709A patent/CZ20012709A3/cs unknown
- 2000-01-27 CN CN00803031A patent/CN1337944A/zh active Pending
- 2000-01-27 EP EP00904570A patent/EP1147078A1/en not_active Withdrawn
- 2000-01-27 HU HU0200605A patent/HUP0200605A3/hu unknown
2001
- 2001-05-31 ZA ZA200104508A patent/ZA200104508B/xx unknown
- 2001-07-24 NO NO20013639A patent/NO20013639D0/no not_active Application Discontinuation

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number	Priority date	Publication date	Assignee	Title
CN102471260A (zh) *	2009-06-30	2012-05-23	盖尔德马研究及发展公司	新型苯磺酰胺化合物、其合成方法及其在药品以及美容用品中的用途
US8633196B2 (en)	2009-06-30	2014-01-21	Galderma Research & Development	Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics
CN102471260B (zh) *	2009-06-30	2014-10-22	盖尔德马研究及发展公司	苯磺酰胺化合物、其合成方法及其在药品以及美容用品中的用途
US8980897B2 (en)	2009-06-30	2015-03-17	Galderma Research & Development	Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics
US9365529B2 (en)	2009-06-30	2016-06-14	Galderma Research & Devlopment	Benzenesulfonamide compounds, method for synthesizing same, and use thereof in medicine as well as in cosmetics

Also Published As

Publication number	Publication date
NZ512025A (en)	2003-08-29
EP1147078A1 (en)	2001-10-24
NO20013639L (no)	2001-07-24
ZA200104508B (en)	2002-09-02
CZ20012709A3 (cs)	2002-04-17
HUP0200605A3 (en)	2005-05-30
HUP0200605A2 (hu)	2002-07-29
CA2356345A1 (en)	2000-08-03
AR035478A1 (es)	2004-06-02
NO20013639D0 (no)	2001-07-24
AU769410B2 (en)	2004-01-29
EA200100808A1 (ru)	2001-12-24
JP2002535383A (ja)	2002-10-22
KR20010089617A (ko)	2001-10-06
BR0007754A (pt)	2001-11-13
AU2630600A (en)	2000-08-18
IL144321A0 (en)	2002-05-23
WO2000044711A1 (en)	2000-08-03

Legal Events

Date	Code	Title
2002-02-27	C06	Publication
2002-02-27	PB01	Publication
2002-04-03	C10	Entry into substantive examination
2002-04-03	SE01	Entry into force of request for substantive examination
2005-12-14	C02	Deemed withdrawal of patent application after publication (patent law 2001)
2005-12-14	WD01	Invention patent application deemed withdrawn after publication

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